کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2050335 1074165 2016 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nuclear pore complex assembly through the cell cycle: Regulation and membrane organization
ترجمه فارسی عنوان
مونتاژ پیچیده هسته ای از طریق چرخه سلولی: تنظیم و سازمان غشاء
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
چکیده انگلیسی

In eukaryotes, all macromolecules traffic between the nucleus and the cytoplasm through nuclear pore complexes (NPCs), which are among the largest supramolecular assemblies in cells. Although their composition in yeast and metazoa is well characterized, understanding how NPCs are assembled and form the pore through the double membrane of the nuclear envelope and how both processes are controlled still remains a challenge. Here, we summarize what is known about the biogenesis of NPCs throughout the cell cycle with special focus on the membrane reorganization and the regulation that go along with NPC assembly.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 582, Issue 14, 18 June 2008, Pages 2004–2016
نویسندگان
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