Keywords: Thyroid; Organoid; p53; NRAS; Thyroid cancer model;
مقالات ISI (ترجمه نشده)
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Keywords: MALDI Imaging; Mass Spectrometry; Molecular Pathology; Pathology Workflow; DNA; desoxyribonuleic acid; EGFR; epidermal growth factor receptor; H&E; hematoxylin and eosin; KRAS; V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; LC; liquid chromatograph
Keywords: ADAM; a disintegrin and metalloproteinase; AKT; protein kinase B; APAF 1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; ATG; autophagy protein; BAK; Bcl 2 homologous antagonist/killer; BAX; Bcl-2 associated -X protein; Bcl-2; B-
Keywords: α-CGRP; alpha-calcitonin gene related peptide; Ang; angiopoietin; AE2; anion exchanger 2; ADP; adenosine diphosphate; ADPKD; autosomal dominant polycystic kidney disease; ATP; adenosine triphosphate; ASBT; sodium-dependent bile acid transporter; AQP; aqu
Keywords: Colorectal cancer; Liquid biopsy; KRAS; NRAS; BRAF;
Keywords: CBD; Central business district; CRE; Community renewable energy; CSA; Commuting satellite account; DR; Demand response; DSM; Demand side management; DSOs; Distribution system operators; EE-IO; Inventories and environmentally extended input-output; EfS; En
Keywords: Melanoma; Next generation sequencing (NGS); BRA; NRAS; Mutation; Variant;
Keywords: BRAF; NRAS; MEK; Kinase inhibitors; Targeted therapy; Melanoma;
Keywords: NRAS; Colorectal carcinoma; Mutation; Metastatic lung tumor; Primary lung carcinoma;
Keywords: Thyroid nodule; Core-needle biopsy; Fine-needle aspiration; Ultrasonography; Cytology; NRAS;
Keywords: 3-AP; 3-aminopyridine-2-carboxaldehyde thiosemicarbazone; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related protein; AMP/ADP/ATP; adenosine mono-, di-, and tri-phosphate; BLM; Bloom syndrome RecQ helicase-like; BRAF; V-raf mu
Keywords: Anaplastic lymphoma kinase (ALK); Driver oncogene; Epidermal growth factor receptor (EGFR); KRAS; Non–small-cell lung cancer; NRAS; Pemetrexed; ROS1
Keywords: Melanoma; Targeted therapy; MAPK signaling; BRAF; MEK; NRAS;
Keywords: BRAF; NRAS; Immunotherapy; Targeted therapy; MITF;
Keywords: PCR; Cancer; Colorectal; NRAS; KRAS; Lung
Keywords: BRAF; diagnosis; KIT; melanoma; molecular testing; NRAS; OncoCarta; pathology; somatic mutations; targeted therapy
Prognostic value of radiologically enlarged lymph nodes in patients with metastatic colorectal cancer: Subgroup findings of the randomized, open-label FIRE-3/AIO KRK0306 trial
Keywords: AJCC; American Joint Committee on Cancer; AP; alkaline phosphatase; BRAF; v-Raf murine sarcoma viral oncogene homolog B; CI; confidence interval; CRC; (colorectal cancer); CT; computed tomography; ECOG; Eastern Cooperative Oncology Group scale of performa
Prevalence and Clinicopathologic Significance of BRAF V600E Mutation in Chinese Multiple Myeloma Patients
Keywords: Hypercalcemia; KRAS; NRAS; Prognosis; Survival;
Non-tumor adjacent tissue of advanced stage from CRC shows activated antioxidant response
Keywords: CRC; colorectal cancer; SIRT3; sirtuin 3; MSI; microsatellite instability; NRAS; neuroblastoma RAS viral oncogene homolog; BRAF; v-raf murine sarcoma viral oncogene homolog B; KRAS; Kirsten rat sarcoma viral oncogene homolog; PI3K; phosphatidylinositide 3
Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK/ERK signalling
Keywords: RAC1; NRAS; MEK; ERK; ER-stress;
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf
NRASQ61R immunohistochemistry detects both NRASQ61R and KRASQ61R mutations in colorectal cancer
Keywords: NRAS; Q61R; colorectal carcinoma; immunohistochemistry;
Original articleMutation analysis of CTNNB1 gene and the ras pathway genes KRAS, NRAS, BRAF, and PIK3CA in eyelid sebaceous carcinomas
Keywords: Eyelid; Sebaceous carcinoma; CTNNB1; NRAS; BRAF; PIK3CA;
The role of RAS mutations in MLL-rearranged leukaemia: A path to intervention?
Keywords: ALL; acute lymphoblastic leukaemia; iALL; infant ALL; MLL; myeloid/lymphoid leukaemia or mixed lineage leukaemia, also known as KMT2A; RAS; rat sarcoma; BCP-ALL; B-cell precursor ALL; EFS; event-free survival; OS; overall survival; WBC; white blood cell c
BRAF, NRAS, KIT, TERT, GNAQ/GNA11 mutation profile analysis of head and neck mucosal melanomas: a study of 42 cases
Keywords: Mucosal melanoma; sinonasal melanoma; oral melanoma; head and neck; mutation; TERT; BRAF; NRAS; KIT; GNAQ/GNA11;
Original contributionAnalysis of KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer
Keywords: Colorectal cancer; Poorly differentiated clusters; KRAS; PIK3CA; NRAS;
8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging
Keywords: 8-oxoG; 7,8-dihydro-8-oxoguanine; 8-oxodG; 7,8-dihydro-8-oxo-2â²-deoxyguanosine; BER; base excision repair; DNA dsbs; double strand breaks; DNA ssbs; single strand breaks; GEF; guanine nucleotide exchange factor; GOrilla; Gene Ontology enrichment analysi
Noise Reduction A Priori Synthetic Over-Sampling for class imbalanced data sets
Keywords: NRAS; SMOTE; OUPS; Class imbalance; Classification;
Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells
Keywords: ASNS; asparagine synthetase; AXL; proto-oncogene tyrosine kinase receptor AXL; BRAF; B-Raf proto-oncogene serine/threonine kinase/v-raf murine sarcoma viral oncogene homolog B; CCL2; chemokine C-C motif ligand 2; CE; coexpression coefficient; CHAC1; ChaC
Targeting mutant NRAS signaling pathways in melanoma
Keywords: Melanoma; NRAS; RAF; PI3K; Ral GEF; Targeted inhibitors;
ReviewSearching for the Chokehold of NRAS Mutant Melanoma
Keywords: ERK; extracellular signal-regulated kinase; GEF; guanine nucleotide exchange factor; HRAS; Harvey-rat-sarcoma homolog; KRAS; Kirsten-rat-sarcoma homolog; MAPK; mitogen-activated protein kinase; NRAS; neuroblastoma rat-sarcoma homolog; RAL; retinaldehyde;
Ki-67, p53, and p16 expression, and G691S RET polymorphism in desmoplastic melanoma (DM): A clinicopathologic analysis of predictors of outcome
Keywords: desmoplastic melanoma; immunohistochemistry; Ki-67; p16; p57; RET polymorphism; BRAF; v-raf murine sarcoma viral oncogene homolog B1; DM; desmoplastic melanoma; KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene; NRAS; neuroblastoma RAS viral (v-r
Sensitivity of plasma BRAFmutant and NRASmutant cell-free DNA assays to detect metastatic melanoma in patients with low RECIST scores and non-RECIST disease progression
Keywords: Melanoma; Circulating tumor DNA (ctDNA); Lactate dehydrogenase (LDH); BRAF; NRAS; Biomarker;
ReviewRAS Mutations as Predictive Biomarkers in Clinical Management of Metastatic Colorectal Cancer
Keywords: Cetuximab; KRAS; mCRC; NRAS; Panitumumab;
Mutation spectra of RAS gene family in colorectal cancer
Keywords: Colorectal cancer; KRAS; NRAS; HRAS; Survival;
Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma
Keywords: Melanoma; CDT2; DTL; Cullin; Ubiquitylation; MLN4924; Pevonedistat; BRAF; NRAS
Phosphoproteomic Analyses of NRAS(G12) and NRAS(Q61) Mutant Melanocytes Reveal Increased CK2α Kinase Levels in NRAS(Q61) Mutant Cells
Keywords: a-loop; activation loop; ERK; extracellular signal-regulated kinase; GO; gene ontology; GTP; guanosine triphosphate; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinase; NRAS; neuroblastoma rat sarcoma viral homolog; PHM; primary human melanocyte
Promoter Methylation of PTEN Is a Significant Prognostic Factor in Melanoma Survival
Keywords: CI; confidence interval; KMC; Korean melanoma cohort; NRAS; neuroblastoma RAS viral oncogene homolog; PTEN; phosphatase and tensin homolog; TCGA-MEL; The Cancer Genome Atlas melanoma; WT; wild-type;
G4 DNA in ras genes and its potential in cancer therapy
Keywords: KRAS; HRAS; NRAS; G-quadruplex; Antigene strategies; Promoter; 5â²-UTR;
Clinical characteristics associated with BRAF, NRAS and KIT mutations in Japanese melanoma patients
Keywords: CSD; chronic sun-induced damage; Melanoma; BRAF; NRAS; KIT; Mitogen-activated protein kinase (MAPK); Japanese;
KRAS, NRAS, BRAF mutations and high counts of poorly differentiated clusters of neoplastic cells in colorectal cancer: observational analysis of 175 cases
Keywords: BRAF; colorectal cancer; KRAS; NRAS; poorly differentiated clusters;
Immunohistochemistry as a potential tool for routine detection of the NRAS Q61R mutation in patients with metastatic melanoma
Keywords: immunohistochemistry; metastatic melanoma; molecular biology; NRAS; Q61R mutation; SP174 clone
Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms
Keywords: BRAF; Vemurafenib; Dabrafenib; Resistance; Acquired; MAPK; NRAS; Splice; MEK1; Meta-analysis
Implementation of a companion diagnostic in the clinical laboratory: The BRAF example in melanoma
Keywords: IVD; in vitro diagnostics; BRAF; V-RAF murine sarcoma viral oncogene homolog B1; SSCP; single-stranded conformation polymorphism analysis; dHPLC; denaturing high performance liquid chromatography; HRMA; high resolution melting analysis; LDTs; Laboratory D
Profiling of Oncogenic Driver Events in Lung Adenocarcinoma Revealed MET Mutation as Independent Prognostic Factor
Keywords: Lung cancer; EGFR; KRAS; ALK; HER2; BRAF; MET; ROS1; RIT1; TTF-1 lung adenocarcinoma; NRAS; Driver mutations; Oncogenic driver mutation; East Asian lung cancer; MET amplification; Targeted therapy; Genetic marker; Biomarker; Molecular classification lung
Optimization of melting analysis with TaqMan probes for detection of KRAS, NRAS, and BRAF mutations
Keywords: Mutation scanning; DNA melting analysis; TaqMan probes; KRAS; NRAS; BRAFDMA, DNA melting analysis; HRMA, high-resolution melting analysis; Tm, melting temperature; PCR, polymerase chain reaction; FFPE, formalin-fixed paraffin-embedded
FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer
Keywords: Cetuximab; FOLFOX4; KRAS; NRAS; OPUS; RAS;
Prevalence of RAS mutations and individual variation patterns among patients with metastatic colorectal cancer: A pooled analysis of randomised controlled trials
Keywords: Panitumumab; mCRC; RAS prevalence; KRAS; NRAS; BRAF;
Dual NRASQ61R and BRAFV600E mutation-specific immunohistochemistry completes molecular screening in melanoma samples in a routine practice
Keywords: Melanoma; BRAF; NRAS; Immunohistochemistry; Molecular analysis
Melanocytic nevi excised during B-Raf proto-oncogene (BRAF) inhibitor therapy: A study of 19 lesions from 10 patients
Keywords: B-Raf proto-oncogene inhibition; CD4; CD8; melanocytic nevi; phosphorylated extracellular signal-regulated kinase; phosphorylated protein kinase B; AKT; protein kinase B; BRAF; B-Raf proto-oncogene; MAPK; mitogen-activated protein kinase; NRAS; neuroblast