Keywords: دامنه اتصال دهنده نوکلئوتیدی; AIM2; absent in melanoma-2; ASC; apoptosis-associated speck-like protein containing a CARD; ATP; adenosine triphosphate; CAPS; cryopyrin-associated periodic syndromes; CARD; caspase recruitment domain; DAMP; danger-associated molecular pattern; DNA; deoxy
مقالات ISI دامنه اتصال دهنده نوکلئوتیدی (ترجمه نشده)
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Keywords: دامنه اتصال دهنده نوکلئوتیدی; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; MSD; membrane-spanning domain; NBD; nucleotide-binding domain; FEV1; forced expiratory volume in 1Â s; Cystic fibrosis; CFTR; Potentiator; Corrector; CFTR modulator; Read-thro
Keywords: دامنه اتصال دهنده نوکلئوتیدی; CARD; caspase recruitment domain; CC; coiled coil; DAMP; danger-associated molecular pattern; DD; death domain; DED; death effector domain; NBD; nucleotide-binding domain; NLR; nucleotide binding and oligomerization domain (NOD) leucine-rich repeat (LRR)-
Keywords: دامنه اتصال دهنده نوکلئوتیدی; α-HL; α-hemolysin; AIM2; absent in melanoma; ASC; apoptosis-associated speck-likeprotein containing a CARD; BIR; baculoviral inhibitor of apoptosis repeat; CARD; caspase activation and recruitment domain; Caspase; cysteine aspartic acid-specific proteas
Keywords: دامنه اتصال دهنده نوکلئوتیدی; AAV; Adeno associated virus; ABC; ATP-binding cassette; ACMG; American College Medical Genetics; AH; Ancestral Haplotype; ASL; airway surface liquid; ATP; Adenosine triphosphate; cas; CRISPR associated; CF; Cystic fibrosis; CFTR; Cystic Fibrosis Transmemb
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP-binding cassette; HUGO; Human Genome Organization; MDR; multidrug resistance; TMD; trans-membrane domain; NBD; nucleotide-binding domain; TMHs; transmembrane helices; LTPs; Lipid Transport Proteins; PM; plasma membrane; PtdSer; phosphatidylserine
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; adenosine triphosphate (ATP)-binding cassette; ASO; antisense oligonucleotides; CPT; camptothecin; DBD; drug-binding domain; DDS; drug delivery system; DOX; doxorubicin; EPR; enhanced permeability and retention effect; IC50 dose; a dose that kills 50
Bombyx ortholog of the Drosophila eye color gene brown controls riboflavin transport in Malpighian tubules
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC transporter; Riboflavin; CRISPR/Cas9; Gene knockout; Malpighian tubules; Silkworm; ABC; ATP-binding cassette; ABCG; ABC transporter G family; AP-3; Adaptor Protein-3; BLOC; biogenesis of lysosome-related organelles complex; BLOS2; biogenesis of lysoso
The role of the NLRP3 inflammasome and the activation of IL-1β in the pathogenesis of chronic viral hepatic inflammation
Keywords: دامنه اتصال دهنده نوکلئوتیدی; CHB; chronic hepatitis B; CHC; chronic hepatitis C; NLRP3; NACHT, LRR, and PYD domains-containing protein 3/cryopyrin; LRR; leucine-rich repeat; NACHT; nucleotide-binding and oligomerization domain; NAD; NACHT-associated domain; NBD; nucleotide-binding do
NLRP3: A promising therapeutic target for autoimmune diseases
Keywords: دامنه اتصال دهنده نوکلئوتیدی; NOD; nucleotide-binding domain; ASC; apoptosis-associated speck-like protein; PRRs; sensor- pattern-recognition receptors; NLRP3; nucleotide-binding oligomerization domain and leucine rich repeat pyrin 3 domain; PAMPs; pathogen-associated molecular patter
Structural patterns of the human ABCC4/MRP4 exporter in lipid bilayers rationalize clinically observed polymorphisms
Keywords: دامنه اتصال دهنده نوکلئوتیدی; 6-MP; 6-mercaptopurine; ABC; ATP-binding cassette; ADV; adefovir; AZT; azidothymidine; BLOSUM; blocks substitution matrix; CFTR; cystic fibrosis transmembrane conductance regulator; Chol; cholesterol; cryo-EM; cryo-electronic microscopy; DMAV; dimethylars
Identification of genomic ATP binding cassette (ABC) transporter genes and Cd-responsive ABCs in Brassica napus
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP binding cassette; TMD; transmembrane domain; NBD; nucleotide-binding domain; CPC; Coding Potential Calculator; ANOVA; analysis of variance; MDR; multidrug resistance; TAP; transporters associated with antigen processing; Brassica napus; ABC trans
NOD1 and NOD2: Molecular targets in prevention and treatment of infectious diseases
Keywords: دامنه اتصال دهنده نوکلئوتیدی; AMP; antimicrobial peptide; CARD; caspase activation and recruitment domain; CMV; cytomegalovirus; DC; dendritic cell; ER; endoplasmic reticulum; GlcNAc; N-acetyl-d-glycosamine; GMDP; glucosaminyl muramyl dipeptide (N-acetyl-d-glucosaminyl-N-acetyl-d-mura
Attachment of a 'molecular spring' restores drug-stimulated ATPase activity to P-glycoprotein lacking both Q loop glutamines
Keywords: دامنه اتصال دهنده نوکلئوتیدی; P-glycoprotein; ABC protein; Disulfide cross-linking; Molecular spring; Drug-stimulated ATPase activity; ABC; ATP-binding cassette; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; human embryonic kidney; TM; transmembrane; TMD; transmembrane do
A short cross-linker activates human P-glycoprotein missing a catalytic carboxylate
Keywords: دامنه اتصال دهنده نوکلئوتیدی; 1, 10-Phenanthroline (PubChemSID: 24278); Cyclosporine A (PubChemCID: 5284373); Verapamil hydrochloride (PubChemCID: 62969); Vinblastine (PubChemCID: 241903); n-dodecyl-β-D-maltoside (PubChemCID: 114880); ABC; ATP-binding cassette; P-gp; P-glycoprotein;
Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency
Keywords: دامنه اتصال دهنده نوکلئوتیدی; P-gp; P-glycoprotein; ABC; ATP-binding cassette; MDR; multidrug resistance; NBD; nucleotide-binding domain; TMD; transmembrane domain; IAAP; [125I]iodoarylazidoprazosin; TMRC; tetramethylrosamine chloride; DMEM; Dulbecco's modified Eagle's medium; FBS
Molecular cloning and expression analysis of five heat shock protein 70 (HSP70) family members in Lateolabrax maculatus with Vibrio harveyi infection
Keywords: دامنه اتصال دهنده نوکلئوتیدی; HSP70; Lateolabrax maculatus; Expression pattern; Immune response; Vibrio harveyi; HSP; heat shock protein; HSC; heat shock cognate; HSPa4; heat shock protein 70Â kDa 4-like; HSPa14; heat shock protein 70Â kDa 14-like; PBS; phosphate-buffered saline; RACE
BAG3 Is a Modular, Scaffolding Protein that physically Links Heat Shock Protein 70 (Hsp70) to the Small Heat Shock Proteins
Keywords: دامنه اتصال دهنده نوکلئوتیدی; chaperones; Hsp27; proteostasis; intrinsically disordered proteins; protein folding; sHsps; small heat shock proteins; Hsp; heat shock protein; BAG3; Bcl-2-associated anthanogene-3; NBD; nucleotide-binding domain; ITC; isothermal titration calorimetry; CS
Interaction of E. coli Hsp90 with DnaK Involves the DnaJ Binding Region of DnaK
Keywords: دامنه اتصال دهنده نوکلئوتیدی; Hsp90; 90-kDa heat shock protein; NBD; nucleotide-binding domain; SBD; substrate-binding domain; NEF; nucleotide exchange factor; BLI; bio-layer interferometry; Hsp40; CbpA; HtpG; molecular chaperone; protein remodeling;
Large Rotation of the N-terminal Domain of Hsp90 Is Important for Interaction with Some but Not All Client Proteins
Keywords: دامنه اتصال دهنده نوکلئوتیدی; Hsp90; 90-kDa heat shock protein; NBD; nucleotide-binding domain; MD; middle domain; DD; dimerization domain; BMH; 1,6-bis(maleimido)hexane; HX; hydrogen exchange; BMOE; 1,6-bis(maleimido)ethane; FOA; 5-fluoroorotic acid; GR; glucocorticoid receptor; GFP;
HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum
Keywords: دامنه اتصال دهنده نوکلئوتیدی; aa; amino acid; ATF6; activating transcription factor 6; BIK; BCL2-interacting killer; BiP; binding immunoglobulin protein; CD86; cluster of differentiation 86; CHOP; CCAAT-enhancer-binding protein homologous protein; Derlin-1; degradation in ER protein 1
Thiol-reactive drug substrates of human P-glycoprotein label the same sites to activate ATPase activity in membranes or dodecyl maltoside detergent micelles
Keywords: دامنه اتصال دهنده نوکلئوتیدی; P-glycoprotein drug-binding sites; ABC protein; n-Dodecyl-β-D-maltoside detergent; Tariquidar; Thiol reactive verapamil and rhodamine; ABC; ATP-binding cassette; DM; n-dodecyl-β-D-maltoside; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; hum
Glycolipid substrates for ABC transporters required for the assembly of bacterial cell-envelope and cell-surface glycoconjugates
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC transporter; ATP-binding cassette transporter; CPS; capsular polysaccharide; CBM; carbohydrate-binding module; core OS; core oligosaccharide; ExPEC; extraintestinal pathogenic E. coli; GT; glycosyltransferase; LPS; lipopolysaccharide; lysoPG; lysophos
Comparison of in silico prediction and experimental assessment of ABCB4 variants identified in patients with biliary diseases
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ATP; Adenosine triphosphate; ABC; ATP-binding cassette; ICP; Intrahepatic cholestasis of pregnancy; LPAC; Low phospholipid-associated cholelithiasis; NBD; Nucleotide-binding domain; PFIC3; Progressive familial intrahepatic cholestasis type 3; Cholestasis;
Nucleotide dependence of the dimerization of ATP binding cassette nucleotide binding domains
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC protein; Tryptophan fluorescence; Dimer; Motor domain; ATPase; ABC; ATP-binding cassette; MJ, single-Cys; single-Trp MJ0796 mutant G14C/C53G/C128I/G174W; MJI; hydrolysis deficient MJ mutant E171Q; NBD; nucleotide-binding domain; NBS; nucleotide-bindin
P-glycoprotein ATPase activity requires lipids to activate a switch at the first transmission interface
Keywords: دامنه اتصال دهنده نوکلئوتیدی; P-glycoprotein; ABC protein; Disulfide cross-linking; Switch; Transmission interface; ATPase activity; ABC; ATP-binding cassette; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; human embryonic kidney; TM; transmembrane; TMD; transmembrane doma
Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides
Keywords: دامنه اتصال دهنده نوکلئوتیدی; Heat-shock proteins; Lipid-binding; Liposomes; Membranes; Stress; Hsp70; seventy-kilodalton heat shock protein; NBD; nucleotide-binding domain; SBD; substrate-binding domain; PC; phosphatidylcholine; PI; phosphatidylinositol; PI(3)P; phosphatidylinositol
Role of the salt bridge between glutamate 546 and arginine 907 in preservation of autoinhibited form of Apaf-1
Keywords: دامنه اتصال دهنده نوکلئوتیدی; Apaf-1; apoptotic protease activating factor-1; CARD; caspase recruitment domain; NOD; nucleotide-binding and oligomerization domain; WRD; WD40-repeat domain; NBD; nucleotide-binding domain; HD1; helical domain 1; WHD; winged-helix domain; HD2; helical do
HspA1A, a 70-kDa heat shock protein, differentially interacts with anionic lipids
Keywords: دامنه اتصال دهنده نوکلئوتیدی; Heat-shock proteins; Lipid-binding; Liposomes; Membranes; Stress; Hsp70; seventy-kilodalton heat shock protein; NBD; nucleotide-binding domain; SBD; substrate-binding domain; CL; cardiolipin (1,1â²,2,2â²-tetramyristoyl cardiolipin); SGC; sulfatide (3-O-
ATP binding to two sites is necessary for dimerization of nucleotide-binding domains of ABC proteins
Keywords: دامنه اتصال دهنده نوکلئوتیدی; 8-azido-ATP-biotin; 8-N3ATP-2â²,3â²-biotin-long chain-hydrazide; ABC; ATP-binding cassette; LRET; luminescence (or lanthanide-based) resonance energy transfer; MJ; single-Cys mutant G14C based on MJ-CL; MJ-CL; Cys-less single-Trp mutant MJ0796-C53G-C128
The maltose ABC transporter: Action of membrane lipids on the transporter stability, coupling and ATPase activity
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP binding cassette; NBD; nucleotide-binding domain; TMD; transmembrane domain; DDM; n-dodecyl-β-d-maltoside; MSP; membrane scaffold protein; EM; electron microscopy; F; fraction; DOPC (18:1 (Î9-Cis) PC); 1,2-dioleoyl-sn-glycero-3-phosphocholine;
Inventory and general analysis of the ATP-binding cassette (ABC) gene superfamily in maize (Zea mays L.)
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP-binding cassette; ORF; open reading frame; TM; transmembrane domains; NBD; nucleotide-binding domain; PGP; P-glycoprotein; qRT-PCR; quantitative real-time PCR; MDRs; multidrug resistance proteins; PDRs; pleiotropic drug resistance proteins; MRPs;
Reversal of multidrug resistance by the inhibition of ATP-binding cassette pumps employing “Generally Recognized As Safe” (GRAS) nanopharmaceuticals: A review
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP-binding cassette superfamily; ART; Antiretroviral therapy; AUC; Area-Under-the-Curve; BCS; Biopharmaceutic Classification System; BCRP; Breast cancer resistance protein; CD; Cyclodextrins; CFR; Code of Federal Regulations; CMC; Critical Micellar
The histidin-loop is essential for transport activity of human MDR3. A novel mutation of MDR3 in a patient with progressive familial intrahepatic cholestasis type 3
Keywords: دامنه اتصال دهنده نوکلئوتیدی; MDR3; multi drug resistance protein 3; PFIC; progressive familial intrahepatic cholestasis; GGT; gamma-glutamyltransferase; WBC; white blood cell Count; HAV; HBV, and HCV, Hepatitis A, B and C; TSH; thyroid stimulating hormon; BSEP; bile salt export pump;
Structural architecture and interplay of the nucleotide- and erythrocyte binding domain of the reticulocyte binding protein Py235 from Plasmodium yoelii
Keywords: دامنه اتصال دهنده نوکلئوتیدی; Malaria; Erythrocyte invasion; Merozoite; Nucleotide-binding domain; Erythrocyte binding domain;
The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP-binding cassette; CTD; C-terminal domain; EMSA; Electrophoretic mobility shift assay; NBD; Nucleotide-binding domain; Uup; ABC ATPase; REG subfamily; NMR; Coiled coil; Non specific DNA binding;
Identification of an amino acid residue in ATP-binding cassette transport G1 critical for mediating cholesterol efflux
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP-binding cassette transporter; RCT; reverse cholesterol transport; NBD; nucleotide-binding domain; MSD; membrane-spanning domain; TM; transmembrane; apoA-I; apolipoprotein A-I; FBS; fetal bovine serum; HEK; human embryonic kidney; SDS-PAGE; sodium
Peroxisomal ABC transporters: Structure, function and role in disease
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABCD; ATP-binding cassette protein subfamily D; AMN; adrenomyeloneuropathy; CCALD; child cerebral ALD; CNS; central nervous system; DHCA; dihydroxycholestanoic acid; DHA; docosahexaenoic acid; GFP; green fluorescent protein; iPS; induced pluripotent stem;
Cloning and functional expression of novel cholesterol transporters ABCG1 and ABCG4 in gonadotropin-releasing hormone neurons of the tilapia
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABCG transporters; teleost; GnRH; lipid; cholesterol; ABC; ATP-binding cassette; AP; adapter primer; apoE; apolipoprotein E; AUAP; abridged universal amplification primer; BSA; bovine serum albumin; Cb; Cerebellum; cDNA; complementary DNA; dNTP; deoxyribo
Toward understanding the mechanism of action of the yeast multidrug resistance transporter Pdr5p: A molecular modeling study
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC transporter; Homology modeling; Membrane protein; Nucleotide-binding domain; Transmembrane domain; Substrate specificityABC, ATP-binding cassette; ECL, extracellular loop; ICL, intracellular loop; LIPS, lipid-facing surface; MDR, multidrug resistance;
Hsp70-1 from Plasmodium falciparum: Protein stability, domain analysis and chaperone activity
Keywords: دامنه اتصال دهنده نوکلئوتیدی; CD; circular dichroism; GdmCl; guanidium chloride; G6PDH; Glucose-6-phosphate dehydrogenase; NBD; nucleotide-binding domain; P-Ctr; substrate-binding domain with C-terminal; Pfhsp70-1; Plasmodium falciparum heat shock protein 70-1; SBD; substrate-binding
On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP binding cassette; ÎpH; transmembrane chemical proton gradient; Îp; proton motive force; MD; membrane domain; NBD; nucleotide-binding domain; TNP-ATP; 2â²-(or-3â²)-O-(trinitrophenyl)-adenosine 5â²-triphosphate; Wt; wildtype; ABC transporter;
Multidrug resistance protein 1 is not associated to detergent-resistant membranes
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC; ATP-binding cassette; AMP; adenosine monophosphate; ATP; adenosine triphosphate; CFTR; cystic fibrosis transmembrane conductance regulator; CRAC; cholesterol recognition/interaction amino acid consensus; DRM; detergent-resistant membrane; HEK; human
Overexpression, purification and characterization of a hexahistidine-tagged recombinant extended nucleotide-binding domain 1 (NBD1) of the Cryptosporidium parvum CpABC3 for rational drug design
Keywords: دامنه اتصال دهنده نوکلئوتیدی; H6-NBD1; hexahistidine-tagged NBD1; HECAMEG; 6-0-[(N-heptylcarbamoyl)methyl]-α-d-glucopyranoside; IPTG; isopropyl-1-thio-β-d-galactopyranoside; Pgp; P-glycoprotein; NBD; nucleotide-binding domain; TMD; transmembrane domain; TNP-ATP; 2â²,3â²-O-(2,4,6-t
Molecular insights into the mechanism of ATP-hydrolysis by the NBD of the ABC-transporter HlyB
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC, ATP-binding cassette; Hly, haemolysin; NBD, nucleotide-binding domain; SAC, substrate-assisted catalysis; TMD, transmembrane domainABC-transporters; Dimerization; Nucleotide-binding domain; Substrate-assisted catalysis; Crystal structures
The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC, ATP-binding cassette; CFTR, cystic fibrosis transmembrane regulator; NBD, nucleotide-binding domain; Pgp, P-glycoprotein; TM, Transmembrane domainABC transporter; ATP hydrolysis; Nucleotide-binding domain; Homology modeling; Multidrug resistance; Seq
In silico modelling of the interaction of flavonoids with human P-glycoprotein nucleotide-binding domain
Keywords: دامنه اتصال دهنده نوکلئوتیدی; Homology modelling; ABCB1; Nucleotide-binding domain; FlavonoidABC, ATP binding cassette; CFTR, cystic fibrosis transmembrane regulator; HIV, human immunodeficiency virus; MDR, multi-drug resistance; NBD, nucleotide-binding domain; PDB, protein databank;
A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K+ channels
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ATP-sensitive K+ channel; Kir6.2; Sulfonylurea receptor; ABC protein; Nucleotide-binding domain; Nicorandil; K+ channel opener;
Wilson's Disease
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ATP7B; copper transporting P-type ATPase; MBS; metal-binding sites; N-domain; nucleotide-binding domain; WD; Wilson's disease;
MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (β-d-glucuronate)
Keywords: دامنه اتصال دهنده نوکلئوتیدی; ABC transporter; ATP-binding cassette transporter; ACNU; 3-[(4-amino-2-methyl-5-pyrimidinyl) methyl]-1-(2-chloroethyl)-1-nitrosourea; ADM; adriamycin; AG-A; agosterol A; azidoAG-A; [125I] 11-azidophenyl agosterol A; AZT; azidothymidine; BSO; buthionine su