Keywords: diabetes; heart failure; echocardiography; screening; DCM; diabetic cardiomyopathy; DD; diastolic dysfunction; DM; diabetes mellitus; GLS; global longitudinal strain; HFpEF; heart failure with preserved ejection fraction; O-GlcNAc; β-N-acetylglucosamine;
مقالات ISI (ترجمه نشده)
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Keywords: Diabetes mellitus; Antioxidants; Oxygen free radicals; Nitrative stress; Animal; Human; eNOS; endothelial nitric oxide synthase; NOS3; nitric oxide synthase 3; cNOS; constitutive nitric oxide synthase; nNOS; neuronal nitric oxide synthase; iNOS; induced n
Keywords: GnRH neurons; Kisspeptin neurons; Female puberty; Chromatin modifications; DNA methylation; Transcriptional repression; Transcriptional activation; Epigenetic regulators; microRNAs; Long noncoding RNAs; 5hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosin
Keywords: Glycolysis; Isoenzymes; Cancer; Spliceforms; Anti-glycolytic agents; Bromopyruvate (PubChem CID: 70684); 2-deoxyglucose (PubChem CID: 9062); 3-PO (PubChem CID: 5720233); PGMI-004A (PubChem CID: 66521681); TEP-46 (Chem CID: 44246499); UDP-GlcNAc; uridine d
Keywords: 3-NT; 3-nitrotyrosine; ADMA; asymmetric dimethyl arginine; Akt; protein kinase B; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; BH2; dihydrobiopterin; BH4; tetrahydrobiopterin; BMR; basal metabolic rate; Cav-1; caveolin-1; CCK; cholecysto
O-GlcNAc site-mapping of liver X receptor-α and O-GlcNAc transferase
Keywords: LXRα; O-GlcNAc; OGT; HCD MS; ETD MS;
O-linked N-acetyl-glucosamine deposition in placental proteins varies according to maternal glycemic levels
Keywords: O-GlcNAc; Hyperglycemia; Placental dysfunction;
O-deGlcNAcylation is required for Entamoeba histolytica-induced HepG2 cell death
Keywords: Entamoeba histolytica; O-GlcNAc; Cell death; OGT; OGA;
Functional significance of O-GlcNAc modification in regulating neuronal properties
Keywords: PTM; post-translational modification; OGT; O-GlcNAc transferase; OGA; O-GlcNAcase; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; GalNAc; N-acetylgalactosamine; Gal; galactose; PSD; postsynaptic density; NF
Research paperOGT-related mitochondrial motility is associated with sex differences and exercise effects in depression induced by prenatal exposure to glucocorticoids
Keywords: AKT; serine/threonine-protein kinases; DEX; dexamethasone; FST; forced swim test; GCs; Glucocorticoids; GSK-3β; glycogen synthase kinase-3β; Miro; mitochondrial Rho GTPase; OFT; open field test; O-GlcNAc; O-linked β-N-acetylglucosamine; OGA; O-GlcNAcas
O-Glycosylation with O-linked β-N-acetylglucosamine increases vascular contraction: Possible modulatory role on Interleukin-10 signaling pathway
Keywords: Cytokine; Vascular dysfunction; O-GlcNAc; ERK 1/2;
Post-translational modifications at the ATP-positioning G-loop that regulate protein kinase activity
Keywords: cAbl; abelson murine leukemia virus proto-oncogene; BCR; breakpoint cluster region; CDK; cyclin-dependent kinase; CML; chronic myeloid leukemia; IR; insulin receptor; O-GlcNAc; O-linked β-N-acetyl glucosamine; PKA; protein kinase A; PKC; protein kinase C
O-GlcNAcylation of cardiac Nav1.5 contributes to the development of arrhythmias in diabetic hearts
Keywords: Diabetic mellitus; Arrhythmias; Nav1.5; O-GlcNAc;
O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease
Keywords: 3xTg-AD; triple transgenic mouse model of Alzheimer's disease; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; Asn; asparagine residue; ATP5A; ATP synthase subunit α; Aβ; amyloid-β peptide; AβPP; amyloid-β precursor protein; ER; endo
NRAGE induces β-catenin/Arm O-GlcNAcylation and negatively regulates Wnt signaling
Keywords: NRAGE; Wnt; β-catenin/Arm; O-GlcNAc;
Quantitative analysis of O-GlcNAcylation in combination with isobaric tag labeling and chemoenzymatic enrichment
Keywords: O-GlcNAc; Enrichment; Thiol-alkyne; Thiol-disulfide exchange; iTRAQ;
Measurement of O-GlcNAcylated endothelial nitric oxide synthase by using 2â²,5â²-ADP-Sepharose pull-down assay
Keywords: Endothelial nitric oxide synthase; O-linked N-acetylglucosamine; 2â²,5â²-ADP-Sepharose; Pull-down assay; NO; nitric oxide; eNOS; endothelial NO synthase; O-GlcNAc; O-linked N-acetylglucosamine;
O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein
Keywords: O-GlcNAc; α-Synuclein; Calpain; Proteolysis; Parkinson's disease;
O-GlcNAc modification of Sp1 mediates hyperglycaemia-induced ICAM-1 up-regulation in endothelial cells
Keywords: O-GlcNAc; Sp1; ICAM-1; Hyperglycaemia;
PUGNAc treatment provokes globotetraosylceramide accumulation in human umbilical vein endothelial cells
Keywords: Glycosphingolipid; Globoside; O-GlcNAc; β-hexosaminidase; Sandhoff disease; Vascular endothelial cell;
O-GlcNAc is required for the survival of primed pluripotent stem cells and their reversion to the naïve state
Keywords: Embryonic stem cells; ESC-derived epiblast stem cells; O-GlcNAc; O-GlcNAc transferase; O-GlcNAcase; ESCs; mouse embryonic stem cells; EpiSCs; mouse epiblast stem cells; ESD-EpiSCs; ESC-derived EpiSCs; rESCs; reverted ESCs; O-GlcNAc; O-linked β-N-acetylgl
Glucosamine induces REDD1 to suppress insulin action in retinal Müller cells
Keywords: F6P; fructose 6-phosphate; HBP; Hexosamine Biosynthetic Pathway; GlcN6P; glucosamine-6-phosphate; GFAT; glutamine-fructose-6-phosphate amidotransferase; UDP-GlcNAc; UDP-N-acetylglucosamine; O-GlcNAc; O-GlcNAcylation; GAM; Glucosamine; VEGF; vascular endot
Research ArticleHyper-O-GlcNAcylation of YB-1 affects Ser102 phosphorylation and promotes cell proliferation in hepatocellular carcinoma
Keywords: Hepatocellular carcinoma; YB-1; O-GlcNAc; Ser102 phosphorylation; Cell proliferation;
O-GlcNAcylation is associated with the development and progression of gastric carcinoma
Keywords: HBP; hexosamine biosynthesis pathway; O-GlcNAc; O-linked β-N-acetylglucosamine; UDP-GlcNAc; uridine diphosphate N-acetylglucosamine; OGT; O-GlcNAc-transferase; OGA; O-GlcNAcase; GC; gastric carcinoma; EGC; early gastric carcinoma; AGC; advanced gastric c
ReviewTNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships
Keywords: AMPK; AMP-activated protein kinase; cTnI; cardiac isoform of troponin I; cTnI-ND; N-terminal truncated cardiac troponin I; DA; distal arthrogryposis; fsTnI; fast skeletal muscle isoform of troponin I; Mst1; mammalian sterile 20-like kinase 1; O-GlcNAc; O-
Aβ-affected pathogenic induction of S-nitrosylation of OGT and identification of Cys-NO linkage triplet
Keywords: OGT; SNO-OGT; O-GlcNAc; Hypo-O-GlcNAcylation; Cys-NO linkages; Aβ neurotoxicity
ReviewRoles of O-GlcNAc in chronic diseases of aging
Keywords: O-GlcNAc; Hyperglycemia; Diabetes; Neurodegenerative disease; Cancer; Hexosamine biosynthetic pathway; O-GlcNAc transferase; O-GlcNAcase;
Post-translational modifications of CD36 (SR-B2): Implications for regulation of myocellular fatty acid uptake
Keywords: SR; scavenger receptor; SSO; sulfo-N-succinimidyl oleate; AMPK; AMP-activated kinase; SHR; spontaneously hypertensive rats; O-GlcNAc; O-linked N-acetylglucosamine; PKA; protein kinase A; PKC; protein kinase C; PAT; palmitoyl-transferase; PPT; palmitoyl-pr
Elevated glucose levels impair the WNT/β-catenin pathway via the activation of the hexosamine biosynthesis pathway in endometrial cancer
Keywords: Elevated glucose levels; WNT/β-catenin; O-GlcNAc; Endometrial cancer;
Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism
Keywords: ARE; antioxidant response element; ATP; adenosine triphosphate; 5-hmC; hydroxymethylcytosine; ATG; AuTophaGy related; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; Drp1; dynamin related protein 1; EpRE; electrophile response element; eNOS; endoth
O-linked N-acetylglucosaminylation of Sp1 interferes with Sp1 activation of glycolytic genes
Keywords: Glycolysis; O-GlcNAc; Sp1; Transcription;
N-acetylglucosamine modification in the lumen of the endoplasmic reticulum
Keywords: Notch; EOGT; O-GlcNAc; UDP-GlcNAc transporter; α-Dystroglycan; GTDC2;
O-linked β-N-acetylglucosamine modification and its biological functions
Keywords: O-GlcNAc; Posttranslational modification; Epigenetic regulation; Plants;
O-GlcNAc signaling in cancer metabolism and epigenetics
Keywords: O-GlcNAc; Posttranslational modifications; Cancer metabolism; Epigenetics;
O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities
Keywords: O-GlcNAc; Sp3; Sp4; Transcription; Interaction;
Nutrient regulation of transcription and signalling by O-GlcNAcylation
Keywords: O-GlcNAc; O-GlcNAc transferase; O-GlcNAcase; Transcription; Signaling; Diabetes; Glucose toxicity; Nutrient sensing
O-GlcNAc glycosylation of p27kip1 promotes astrocyte migration and functional recovery after spinal cord contusion
Keywords: Spinal cord injury; Astrocytes; p27kip1; O-GlcNAc; Phosphorylation
Euglena in time: Evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry
Keywords: Euglena gracilis; Evolution; Transcriptome; Natural products; Base J; Gene silencing; O-GlcNAc
Site-specific structural characterization of O-glycosylation and identification of phosphorylation sites of recombinant osteopontin
Keywords: OPN; osteopontin; PTM; post-translational modification; O-GlcNAc; O-linked β-N-acetylglucosamine; MALDI-TOF; matrix-assisted laser desorption ionization-time of flight; MS; mass spectrometry; PMF; peptide mass fingerprint; MS/MS; tandem mass spectrometry
Enrichment of O-GlcNAc-modified peptides using novel thiol-alkyne and thiol-disulfide exchange
Keywords: O-GlcNAc; Enrichment; Thiol-alkyne; Thiol-disulfide exchange;
Inhibition of mTOR affects protein stability of OGT
Keywords: O-GlcNAc; OGT; Protein stability; Autophagy; mTOR inhibitor; Proteasomal degradation;
Validation of the reliability of computational O-GlcNAc prediction
Keywords: O-GlcNAc; Prediction program; YinOYang server; dbOGAP database; OGlcNAcScan;
Basal transcription is regulated by lipopolysaccharide and glucosamine via the regulation of DNA binding of RNA polymerase II in RAW264.7 cells
Keywords: Glucosamine; RNAPII; O-GlcNAc
Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy
Keywords: O-GlcNAc; ThiametG; Tau aggregation; Alzheimer's Disease; O-tau(S400) antibody; OGA; rTg4510;
Cell cycle-dependent O-GlcNAc modification of tobacco histones and their interaction with the tobacco lectin
Keywords: Cell cycle; Histone; Nictaba; O-GlcNAc; Protein interaction; Tobacco(Nt-NCAPP1), N. tabacum non-cell-autonomous pathway protein1; (OGA), O-GlcNAcase; (OGT), O-GlcNAc transferase; (O-GlcNAc), O-linked N-acetylglucosamine; (SPY), SPINDLY; (SEC), SECRET AGEN
Development of in vitro model of insulin receptor cleavage induced by high glucose in HepG2 cells
Keywords: ADAM; a disintegrin and metalloprotease; BAPTA-AM; O,Oâ²-Bis [2-aminophenyl] ethyleneglycol-N,N,Nâ²,Nâ²-tetraacetic acid tetraacetoxymethyl ester; DON; deoxynorleucine; ICT-EIA; immune complex transfer enzyme immunoassay; IR; insulin receptor; OGA; β-
Characterization of the specificity of O-GlcNAc reactive antibodies under conditions of starvation and stress
Keywords: CTD110.6; O-GlcNAc; Nutrient deprivation; Specificity; Stress response
OGT and OGA expression in postmenopausal skeletal muscle associates with hormone replacement therapy and muscle cross-sectional area
Keywords: CO; control; CSA; cross-sectional area; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HRT; hormone replacement therapy; OGA; O-GlcNAcase; O-GlcNAc; O-linked N-acetylglucosamine; OGT; O-GlcNAc transferase; PI3K; phosphatidylinositol-3-kinase; PT; power
Requirement of decreased O-GlcNAc glycosylation of Mef2D for its recruitment to the myogenin promoter
Keywords: O-GlcNAc; Glycosylation; Mef2D; Myogenesis; Myogenin;
Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400
Keywords: O-GlcNAc; Tau; Site-specific; Monoclonal antibody; OGA;