Keywords: Hepatocellular carcinoma; ICG; Transporter; MDR3; OATP1B3;
مقالات ISI (ترجمه نشده)
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Keywords: Microcystins; OATP1B1; OATP1B3; Cell culture model; Aggregate; Cyanotoxins;
The N-terminal region of organic anion transporting polypeptide 1B3 (OATP1B3) plays an essential role in regulating its plasma membrane trafficking
Keywords: OATP1B3; organic anion transporting polypeptide 1B3; OATP1B3-WT; organic anion transporting polypeptide 1B3-wildtype; OATP1B3-Î28; organic anion transporting polypeptide 1B3 lacking the N-terminal 28 amino acids; CK-2; casein kinase-II; PKC; protein kina
Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case
Keywords: Cyclosporin (PubChem CID: 122172945); Atazanavir (PubChem CID: 86601659); Nelfinavir (PubChem CID: 122130496); Itraconazole (PubChem CID: 86611782); Amphotericin B (PubChem CID: 122130047); Ciprofloxacin (PubChem CID: 92135222); Clopidogrel (PubChem CID:
Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity
Keywords: BNPP; bis-p-nitrophenyl phosphate; CES; carboxylesterases; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; OATP; organic anion transporting polypeptide; PP; protein phosphatase; PNP; p-nitrophenyl; PNPA; p-nitrophenyl acetate; PVDF; po
Pharmacokinetic effects of curcumin on docetaxel mediated by OATP1B1, OATP1B3 and CYP450s
Keywords: Curcumin; Docetaxel; Pharmacokinetics; OATP1B1; OATP1B3; Human liver microsomes;
The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice
Keywords: ABC; ATP-binding cassette; AUC; area under the concentration-time curve; DDI; drug-drug interactions; E2G; estradiol 17β-d-glucuronide; i.v.; intravenous; OATP; organic anion-transporting polypeptide; TKI; tyrosine kinase inhibitor; UGT1A1; UDP-glucuro
Naringin attenuates the cytotoxicity of hepatotoxin microcystin-LR by the curious mechanisms to OATP1B1- and OATP1B3-expressing cells
Keywords: FCS; fetal calf serum; MC-LR; microcystin-LR; IC50; half maximal inhibitory concentration; Km; Michaelis constant; MEM; minimum essential medium; MTT; 3-(4,5-di-methylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; OATP; organic anion transporting polypept
Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3
Keywords: Hepatotoxicity; Microcystin-LR; OATP1B1; OATP1B3; Okadaic acid; BSP; bromosulfophthalein; DHEAS; dehydroepiandrosterone sulfate; DMF; dose modifying factor; FCS; fetal calf serum; MC-LR; microcystin-LR; IC50; half maximal inhibitory concentration; MEM; mi
Mechanistic study of IR-780 dye as a potential tumor targeting and drug delivery agent
Keywords: IR-780 iodide; Glycolysis; Plasma membrane potential; OATP1B3; Nitrogen mustard;
Consumption of baby kale increased cytochrome P450 1A2 (CYP1A2) activity and influenced bilirubin metabolism in a randomized clinical trial
Keywords: BHNRC; Beltsville Human Nutrition Research Center; CYP1A2; cytochrome P450 family 1 subfamily A member 2; CYP2A6; cytochrome P450 family 2 subfamily A member 6; CV; control vegetables; GST; glutathione S-transferase; GSTA; glutathione S-transferase alpha;
Role of hypoxia inducible factor-1α in the regulation of the cancer-specific variant of organic anion transporting polypeptide 1B3 (OATP1B3), in colon and pancreatic cancer
Keywords: OATP1B3; Splicing variants; Hypoxia; Colon cancer; Pancreatic cancerOATP, organic anion transporting polypeptide; WT, wildtype; HRE, hypoxia response element; HIF-1, hypoxia inducible factor-1; EMSA, electrophoretic mobility shift assay; RT-PCR, reverse t
Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design
Keywords: Metabolic stability; Human liver microsomes; Human hepatocytes; Intrinsic clearance; Hepatic transporters; Drug discovery; ADME; Absorption, distribution, metabolism, and excretion; AO; Aldehyde oxidase; BCRP; Breast cancer resistance protein; CYP; Cytoch
Fluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3
Keywords: Transporter; Transport; Fluorescence; OATP1B1; OATP1B3
Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2
Keywords: Boswellic acids; Permeability; P-glycoprotein; OATP1B3; MRP2; Caco-2; Absorption;
Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes
Keywords: Antineoplastic drugs; Fluorescent substrate; Imaging; OATP1B3; Rapid screening