Keywords: NO; nitric oxide; SNP; sodium nitroprusside; TNG; nitroglycerine; SHR; spontaneously hypertensive rats; TERPY; [Ru(terpy)(bdq)NO]3+; Eâ; endothelium-denuded; E+; endothelium-intact; 2K; sham-operated rats; 2K-1C; two-kidney one-clip, renal hypertensive
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Keywords: sGC (soluble guanylate cyclase); Nitric oxide; ODQ; Surface plasmon resonance;
Keywords: ALDH; aldehyde dehydrogenase; CB25; 1-{[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]methyl}-1H-indole-2,3-dione; cGMP; 3â²,5â²-cyclic guanosine monophosphate; DEA/NO; 2,2-diethyl-1-nitroso-oxyhydrazine; DMSO; dimethyl sulfoxide; DPI; diphenyleneiodoniu
Keywords: ACh; acetylcholine chloride; PE; phenylephrine; l-NAME; NG-nitro-l-arginine methylester; ODQ; 1H-1,2,4-oxadiazolo-4,3-quinoxalin-1-one; SNP; sodium nitroprusside; DHE; dihydroethidium; NO; nitric oxide; cGMP; cyclic guanosine monophosphate; sGC; soluble g
Keywords: ADP; adenosine 5-diphosphate; ELISA; enzyme-linked immunosorbent assay; HPLC; high-performance liquid chromatography; IBMX; 3-isobutyl-1-methylxanthine; ODQ; 1,2,4-oxadiazolo[4,3-a]quinoxalin-1-one; PBS; phosphate-buffered saline; Cigarette smoke; Moist t
Involvement of the NO/sGC/cGMP/K+ channels pathway in vascular relaxation evoked by two non-quinazoline α1-adrenoceptor antagonists
Keywords: 4-AP; 4-amynopiridine; AC; adenylyl cyclase; BPH; benign prostatic hyperplasia; COX; cyclooxygenase; DAG; diacylglycerol; EDHF; endothelium-derived hyperpolarizing factor; eNOS; endothelial NO synthase; GLI; glibenclamide; HAEC; human aortic endothelial c
Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity
Keywords: Mercaptopyruvate; Hydrogen sulfide; Vasorelaxation; Aorta; 3-Mercaptopyruvate sulfurtransferase knockout mice; 3-MST; 3-mercaptopyruvate sulfurtransferase; CAT; cysteine aspartate aminotransferase; CBS; cystathionine-β-synthase; CSE; cystathionine-γ-lya
Thiocarbonyl-bound metallonitrosyl complexes with visible-light induced DNA cleavage and promising vasodilation activity
Keywords: bpy; 2,2-bipyridine; COSY; homonuclear correlation spectroscopy; cPTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; HMBC; heteronuclear multiple quantum coherence; HMQC; heteronuclear multibond coherence; L-NAME; N-nitro-l-arginine
Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation
Keywords: 3-MST; 3-mercaptopyruvate sulfurtransferase; 3B7NI; 3-bromo-7-nitroindazole; AOAA; aminooxyacetic acid; CBS; cystathionine-β-synthase; CO; carbon monoxide; CSE; cystathionine gamma lyase; eNOS; endothelial nitric oxide synthase; nNOS; neuronal nitric oxi
Endogenous nitric oxide inhibits spinal NMDA receptor activity and pain hypersensitivity induced by nerve injury
Keywords: Synaptic plasticity; Synaptic transmission; Signal transduction; Ion channel; Neuropathic pain; Dorsal horn neurons; NO; nitric oxide; nNOS; neuronal nitric oxide synthase; NMDAR; N-methyl-d-aspartate receptor; ODQ; 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1
Both nitric oxide and nitrite prevent homocysteine-induced endoplasmic reticulum stress and subsequent apoptosis via cGMP-dependent pathway in neuronal cells
Keywords: Nitric oxide; Nitrite; Endoplasmic reticulum stress; Apoptosis; cGMP; Neuronal cells; 7-AAD; 7-aminoactinomycin D; AD; Alzheimer's disease; ATF6; activating transcription factor 6; Br-cGMP; 8-bromo-cyclic cyclic guanosine 3â²,5â²-monophosphate; cGMP; cy
Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice
Keywords: 8-Br-PET-cGMP; 8-Bromo-β-phenyl-1, N2-ethenoguanosine-cGMP; ACSF; artificial cerebrospinal fluid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; cGMP; cyclic guanosine monophosphate; D-AP5; d-(-)-2-amino-5-phosphonopentanoic aci
Heme oxygenase-1 metabolite biliverdin, not iron, inhibits porcine reproductive and respiratory syndrome virus replication
Keywords: PRRSV; porcine reproductive and respiratory syndrome virus; PAM; porcine alveolar macrophage; MARC-145; african green monkey kidney cells; HO-1; heme oxygenase-1; ROS; reactive oxygen species; BV; biliverdin; BR; bilirubin; Hb; hemoglobin; NO; nitric oxid
Peroxiredoxin-2 nitrosylation facilitates cardiomyogenesis of mouse embryonic stem cells via XBP-1s/PI3K pathway
Keywords: ES cell; embryonic stem cell; EB; embryoid body; DHE; Dihydroethidium; DHR; Dihydrorhodamine 123; DTT; Dithiothreitol; GO; Gene Ontology; GSNO; S-nitrosoglutathione; H2O2; hydrogen peroxide; NO; nitric oxide; ODQ; 1H-[1,2,4]oxadiazolo[4,3a]quinoxalin-1-on
The versatile ruthenium(II/III) tetraazamacrocycle complexes and their nitrosyl derivatives
Keywords: acn; acetonitrile; 4-acpy; pyridine-4-acetyl; acv; (acyclovir), 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one); am(m)ine; ammine, amine, and/or tetraazamacrocycle; ampy; 2-aminomethylpyridine; [15]aneN4; 1,4,8,12-tetraazacyclopentadecane;
Nitric oxide-repressed Forkhead factor FoxE1 expression is involved in the inhibition of TSH-induced thyroid peroxidase levels
Keywords: Thyroperoxidase (TPO); Nitric oxide (NO); Thyroid stimulating hormone (TSH); Forkhead box protein E1 (FoxE1); TPO; Thyroperoxidase; TSH; Thyroid Stimulating Hormone; cAMP; Cyclic Adenosine Monophosphate; NF-κB; Nuclear Factor-kappa B; NO; Nitric Oxide; N
Sodium nitrite causes relaxation of the isolated rat aorta: By stimulating both endothelial NO synthase and activating soluble guanylyl cyclase in vascular smooth muscle
Keywords: cGMP; cyclic guanosine monophosphate; cPTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potassium salt; eNOS; endothelial nitric oxide synthase; HUVEC; human umbilical vein endothelial cells; L-NAME; NÏ-nitro-l-arginine methyl este
Des-aspartate angiotensin I (DAA-I) reduces endothelial dysfunction in the aorta of the spontaneously hypertensive rat through inhibition of angiotensin II-induced oxidative stress
Keywords: ACE; angiotensin converting enzyme; AT1R; angiotensin II type 1 receptor; AT2R; angiotensin II type 2 receptor; cGMP; cyclic guanosine monophosphate; DAA-I; Des- aspartate angiotensin I; DAG; diacylgylcerol; EDCF; endothelium-derived contracting factor; E
S-nitrosylation of PDE5 increases its ubiquitin-proteasomal degradation
Keywords: cGMP; cyclic guanosine monophosphate; DETA-NO; diethylenetriamine NONOate; GSNO; S-nitrosoglutathione; KT5823; 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9S,12R-epoxy-1H-diindolo[1,2,3-fg:3â²,2â²,1â²-kl]pyrrolo[3][1,6]benzodiazocine-10-car
Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus
Keywords: Nitric oxide; μ-Opioid receptor; Locus coeruleus; Cyclic guanosine monophosphate; Reactive oxygen species; Slice; Firing; A 350619; 3-[2-[(4-chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride; aCSF; artificial cerebrospinal f
Presynaptic cell type-dependent regulation of GABAergic synaptic transmission by nitric oxide in rat insular cortex
Keywords: ACSF; artificial cerebrospinal fluid; BSA; bovine serum albumin; cGMP; cyclic guanosine monophosphate; CTA; conditioned taste aversion; DAB; 3-3â²-diaminobenzidine; EGTA; ethylene glycol tetraacetic acid; FS; fast-spiking interneuron; GC; guanylyl cyclas
The reaction products of sulfide and S-nitrosoglutathione are potent vasorelaxants
Keywords: ABS; absorbance; AS; Angeli's salt; AUC; area under the curve; cPTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; GSNO; S-nitrosoglutathione; EPR; electron paramagnetic resonance; MGD; N-(dithiocarboxy)-N-methyl-D-glucamine; NAC; N-
Soluble adenylyl cyclase accounts for high basal cCMP and cUMP concentrations in HEK293 and B103 cells
Keywords: cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cNMP; 3â²,5â²-cyclic nucleoside monophosphate; cUMP; uridine 3â²,5â²-cyclic monophosphate; pGC; particulate
Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity
Keywords: cGK(I); cGMP-dependent protein kinase (I); (e)NOS; (endothelial) nitric oxide synthase; l-NAME; NÏ-nitro-l-arginine methyl ester; MMEvc; methylene chloride-methanol (1:1) extract of V. cienkowskii; NA; noradrenaline; NO; nitric oxide; ODQ; 1-H-[1,2,4]-ox
Nitric oxide improves the hemodynamic performance of the hypoxic goldfish (Carassius auratus) heart
Keywords: NOS; nitric oxide synthase; NO; nitric oxide; SV; stroke volume; sGC; soluble guanylyl cyclase; HIF-1α; hypoxia inducible factor α; Hb; hemoglobin; CO; cardiac output; HR; heart rate; SW; stroke work; L-NMMA; NG-monomethyl-L-arginine; GSNO; S-nitrosoglu
Regular ArticlePeroxynitrite may affect clot retraction in human blood through the inhibition of platelet mitochondrial energy production
Keywords: CRR; clot retraction rate; ROTEM; rotational thromboelastometry; CT; clotting time; MCF; maximum clot firmness; PRP; platelet-rich plasma; ODQ; H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one; CCCP; Carbonyl cyanide 3-chlorophenylhydrazone; TMRM; tetramethylrh
Retrograde response in axotomized motoneurons: Nitric oxide as a key player in triggering reversion toward a dedifferentiated phenotype
Keywords: AVVs; Adenoviruses; C3; component 3; CAMs; cell adhesion molecules; cGMP; cyclic guanosine monophosphate; CNS; central nervous system; HMNs; hypoglossal motoneurons; HN; hypoglossal nucleus; LVV; lentiviral; mFR; mean firing rate; MHC-I; major histocompat
Arginase inhibition reduces interleukin-1β-stimulated vascular smooth muscle cell proliferation by increasing nitric oxide synthase-dependent nitric oxide production
Keywords: IL-1β; interleukin-1β; VSMC; vascular smooth muscle cells; iNOS; inducible nitric oxide synthase; cGMP; cyclic guanosine monophosphate; AS; antisense; RT-PCR; reverse transcription polymerase chain reaction; eNOS; endothelial nitric oxide synthase; nNOS
Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity
Keywords: cGMP; cyclic guanosine monophosphate; cGK; cGMP-dependent protein kinase; IPA/NO; isopropylamine NONOate; MCA; middle cerebral artery; ODQ; 1H-[1,2,4]-oxadiazolo[4,3-a]quinoxalin-1-one; PDBu; phorbyl 12,13-dibutyrate; ROS; reactive oxygen species; Rp-8-pC
Peroxynitrite - altered platelet mitochondria-A new link between inflammation and hemostasis
Keywords: CRR; clot retraction rate; ODQ; 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; CCCP; Carbonyl cyanide 3-chlorophenylhydrazone; TMRM; tetramethylrhodamine methyl ester; Clot retraction; Energy metabolism; Fibrinolysis; Mitochondria; Platelets; Peroxynitrite;
The ruthenium NO donor, [Ru(bpy)2(NO)SO3](PF6), inhibits inflammatory pain: Involvement of TRPV1 and cGMP/PKG/ATP-sensitive potassium channel signaling pathway
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; CFA; complete Freund's adjuvant; cGMP; cyclic monophosphate guanosine; GLY; glybenclamide; HTAB; hexadecyltrimethylammonium bromide; KT5823; 2, 3, 9,10, 11, 12-hexahydro-10R-methoxy-2, 9-dime
Mechanisms for cellular NO oxidation and nitrite formation in lung epithelial cells
Keywords: Cp; ceruloplasmin; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IFN-γ; interferon-γ; IL-1β; interleukin-1β; siRNA; small-interfering ribonucleic acid; Hb; hemoglobin; PPD; p-phenylenediamine; SO; su
Angiotensin AT2 receptor activates the cyclic-AMP signaling pathway in eel
Keywords: ATIP; AT2 receptor interacting protein; CRE; cAMP-responsive element; DIG; digoxigenin; GC; guanylyl cyclase; GPCR; G-protein coupled receptor; HEK293; human embryonic kidney cell line 293; KT5823; 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9
Angiotensin (5-8) modulates nociception at the rat periaqueductal gray via the NO-sGC pathway and an endogenous opioid
Keywords: AA; antinociceptive activity; Angs; angiotensins; Ang-R; Ang receptor; ANOVA; analysis of variance; AT; Ang type; ATR; Ang type receptor; DMSO; dimethylsulfoxide; HR; heart rate; MAP; mean arterial pressure; nNOS; neuronal nitric oxide synthase; NO; nitri
Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells
Keywords: AKT; protein kinase B; L-Arg; l-arginine; L-NAME; N-nitro-l-arginine methyl ester; NO; nitric oxide; NMDA; N-methyl-d-aspartate; MK-801; (5R,2S)-(1)5methyl-10,11-dihydro-5H-dibenzo [a,d] cyclohepten-5,10-imine hydrogen maleate; NOS; nitric-oxide synthase;
Spasmolytic effect of curcumin on goat ruminal artery is endothelium independent and by activation of sGC
Keywords: Goat ruminal artery; Curcumin; s-Guanylatecyclase; L-NAME; ODQ; 4-AP
Cell-Specific Deletion of Nitric Oxide-Sensitive Guanylyl Cyclase Reveals a Dual Pathway for Nitrergic Neuromuscular Transmission in the Murine Fundus
Keywords: cGMP; Knockout Mice; Electrical Field Stimulation; Mouse Model; CCh; carbachol; DEA-NO; 2-(N,N-diethylamino)-diazenolate-2-oxide diethylammonium salt; cGMP; guanosine 3â²,5â²-cyclic monophosphate; EFS; electric field stimulation; GCKO; guanylyl cyclase
The nitric oxide pathway participates in lordosis behavior induced by central administration of leptin
Keywords: Leptin; Lordosis behavior; Nitric oxide; Nitric oxide synthase; Cyclic GMP; L-NAME; ODQ; KT5823
Relaxant effects of Artemisia ludoviciana on isolated rat smooth muscle tissues
Keywords: HEAl; hexanic extract from Artemisia ludoviciana; DEAl; dichloromethanic extract from Artemisia ludoviciana; MEAl; methanolic extract from Artemisia ludoviciana; KCl; potassium chloride; ODQ; 1-H-[1,2,4]-oxadiazolo-[4,3a]-quinoxalin-1-one; l-NAME; NÏ-nit
Analysis of responses to glyceryl trinitrate and sodium nitrite in the intact chest rat
Keywords: GTN; glyceryl trinitrate/nitroglycerin; GDN; glyceryl dinitrate; NO; nitric oxide; S-NO; S-nitrosothiol; GSNO; S-nitrosoglutathione; sGC; soluble guanylyl cyclase; ALDH2; mitochondrial aldehyde dehydrogenase; XOR; xanthine oxidoreductase; ODQ; 1H-[1,2,4]-
Endothelial nitric oxide and 15-lipoxygenase-1 metabolites independently mediate relaxation of the rabbit aorta
Keywords: AA; arachidonic acid; 15-LO-1; 15-lipoxygenase-1; THETA; 11,12,15-trihydroxyeicosatrienoic acid; HEETA; 15-hydroxy-11,12-epoxyeicosatrienoic acid; NO; nitric oxide; ACH; acetylcholine; LNA; nitro-l-arginine; LO; lipoxygenase; GC; guanylate cyclase; NDGA;
Endothelium-dependent and independent vasorelaxation induced by an n-butanolic fraction of bark of Scutia buxifolia Reiss (Rhamanaceae)
Keywords: ACh; acetylcholine; AcOEt; ethyl acetate fraction; BKCa; large conductance Ca2+-activated K+ channel; BuOH; butanolic fraction; cGMP; guanosine 3â²,5â²-cyclic monophosphate; DCM; dichloromethane fraction; GLI; glibenclamide; ibTX; iberiotoxin; L-NAME; N
Nitric oxide signaling modulates cholinergic synaptic input to projection neurons in Drosophila antennal lobes
Keywords: Ach; acetylcholine; ALs; antennal lobes; BSA; bovine serum albumin; cGMP; cyclic guanosine monophosphate; CNS; central nervous system; CS; Canton-S; DMSO; dimethyl sulfoxide; EGTA; ethylene glycol tetraacetic acid; EPSPs; excitatory postsynaptic potential
Ethanol induces vascular relaxation via redox-sensitive and nitric oxide-dependent pathways
Keywords: NO; Nitric oxide; eNOS; endothelial NO synthase; nNOS; neuronal NO synthase; ROS; reactive oxygen species; ([Ca2Â +]c); Cytosolic calcium concentration; ADH; alcohol dehydrogenase; ([NO]c); Cytosolic NO concentration; VSMCs; vascular smooth muscle cells;
The phytoestrogen 8-prenylnaringenin inhibits agonist-dependent activation of human platelets
Keywords: 8-PN; 8-prenylnaringenin; BSA; bovine serum, albumin; ERK1/2; extracellular signal-regulated kinase; MAPK; mitogen-activated protein kinase; NO; nitric oxide; ODQ; 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; PKA; protein kinase A; PKG; protein kinase G;
Mechanisms mediating effects of nitric oxide on perifornical lateral hypothalamic neurons
Keywords: aCSF; artificial cerebrospinal fluid; BF; basal forebrain; BIC; bicuculline, a GABAA receptor antagonist; cGMP; cyclic guanosine monophosphate; CPT; 8-cyclopentyl-1,3-dimethylxanthine (an adenosine A1 receptor antagonist); EEG; electroencephalogram; GABA;
Vasorelaxant and antihypertensive effect of Cocos nucifera Linn. endocarp on isolated rat thoracic aorta and DOCA salt-induced hypertensive rats
Keywords: CNE; Cocos nucifera Linn. ethanolic extract; NO; nitric oxide; GC; guanylate cyclase; NE; norepinephrine; PhE; phenylephrine hydrochloride; l-NNA; NG-nitro-l-arginine; ODQ; 1H-[1,2,4]-oxadiazolo-[4,3-A]-quinoxalin-1-one; Ca2+; calcium ion; cAMP; cyclic ad
Evidence for the involvement of neuronal nitric oxide synthase and soluble guanylate cyclase on cognitive functions in rats
Keywords: 3-bromo-7-nitroindazole; ODQ; NO; Guanylate cyclase; Working memory; Reference memory; Emotional learning; Rats
Identification of LY83583 as a specific inhibitor of Candida albicans MPS1 protein kinase
Keywords: LY83583; 6-anilino-5,8-quinolinedione; MBP; myelin basic protein; ODQ; 1H-[1,2,4]oxidiazolo[4,3-a]-quinoxaline-1-one; Protein kinase inhibitor; Monopolar spindle 1; Antifungal agent; Selective toxicity; Docking model; Guanylate cyclase inhibitor;
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one induces cell cycle arrest and apoptosis in HeLa cells by preventing microtubule polymerization
Keywords: ODQ; Tubulin; Microtubule; Cell cycle arrest; Apoptosis