Keywords: HIV; human immunodeficiency virus; SA; South Africa; NOx; oxides of nitrogen; BW; birthweight; Nrf2; nuclear factor (erythroid-derived 2)-like 2; Keap1; kelch-like ECH-associated protein 1; mi-RNA; microRNA; NO; nitrites/nitrates; MDA; malondialdehyde; ER
مقالات ISI (ترجمه نشده)
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Keywords: Carcinogenesis; Chemoprevention; Chemotherapy; Oxidative stress; Nrf2; Phytochemicals; AKT; protein kinase B; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ATF-2; activating transcriptional factor; BBN; N-butyl-N-(4-hydroxybutyl)n
Keywords: A; adenine; A549; adenocarcinomic human alveolar basal epithelial cells; AKR1C3; Aldo_Keto Reductase; BaP; Benzo(a)pyrene; C; cytosine; CI; Confidence interval; CO; carbon monoxide; CXCL 13; motif chemokine ligand 13; CYP1B1; cytochrome P450 1B1; DKK2; Di
Keywords: 8OH-G; 8-hydroxyguanine; CK; Creatine kinase, 2; CS; citrate synthase; DNMT1-3A-3B; DNA methyltransferase 1, 3A, 3B; DRP1; dynamin-related protein 1; p-DRP1; dynamin-phosphorylated related protein 1; ETC; electron transport chain; HO-1; heme oxygenase;
Keywords: Hx; hypoxanthine; 8-oxoG; 8-oxoguanine; DNA damage; Cancer; Hypoxanthine; Inosine; Inflammation; MPG; Mutation; OGG1; Reactive oxygen and nitrogen species; Base excision repair; Site-specific mutagenesis; Deamination damage;
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain-derived neurotrophic factor; COMT; cathecol-O-methyltransferase; CRY2; chryptochrome 2; d; Cohen's d effect size; dex/CRH; dexamethasone/corticotropin releasing hormone; DSM; Diagnos
Keywords: AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se
Keywords: A-bomb; atomic bomb; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; BER; base excision repair; Ca2+; calcium ions; CDKN1A; cyclin-dependent kinase inhibitor 1A; CHO; Chinese hamster ovary; COX-2; cycloox
Keywords: DIQ; 1,5-dihydroxyisoquinoline; 4-AN; 4-amino-1,8-naphthalimide; 6,4PPs; 6,4-photoproducts; 8-oxodG; 8-oxo-2â²-deoxyguanosine; OGG1; 8-oxoguanine glycosylase 1; APE1; AP-endonuclease; ATM; ataxia telangiectasia-mutated gene; BER; base excision repair; BR
Keywords: Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Keywords: AD; Alzheimer's disease; AP site; apurinic/apyrimidinic site; APE1; apurinic/apyrimidinic endonuclease 1; Aβ; amyloid beta; BER; base excision repair; CaMKII; Ca2 +/Calmodulin-Dependent Protein Kinase II; CDK; cyclin-dependent kinase; CREB; cAMP respons
Keywords: AL; ad libitum; BAP; Biomarkers of Aging Program; CR; caloric restriction; EM; Emory-Morse; GSH; glutathione; GSSG; glutathione disulfide; mTOR; mammalian target of rapamycin; NCTR; National Center for Toxicological Research; NIA; National Institute on Ag
Keywords: 8-oxoG; 7,8-dihydro-8-oxoguanine; AECs; airway epithelial cells; AHR; airway hyperresponsiveness; APE1; AP-endonuclease 1; AP sites; apurinic/apyrimidinic site; BER; base excision repair; BALF; bronchoalveolar lavage fluid; CA; comet assay; DSB; double-st
Keywords: γ-H2AX; gamma-H2AX; 8-OH-dG; 8-hydroxyguanosine; ANOVA; analysis of variance; BAL; bronchoalveolar lavage; DSB; DNA double-strand breaks; LDH; lactate dehydrogenase; MNP; microscale and nanoscale particles; NO; nitric oxide; OGG1; 8-oxoguanine DNA glycos
Aging related changes in circulating reactive oxygen species (ROS) and protein carbonyls are indicative of liver oxidative injury
Keywords: Aging; Radical oxygen species (ROS); FRAP; Plasma carbonyls; 8-hydroxy-2â²-deoxyguanosine (8-OHdG); DNA repair enzymes; APE1; OGG1; UNG genes;
DNA methylation: A critical epigenetic mechanism underlying the detrimental effects of airborne particulate matter
Keywords: 5-mC; 5-methylcytosine; ACE; Angiotensin I converting enzyme; APEX; Apurinic/apyrimidinic endodeoxyribonuclease; BC; black carbon; CD40LG; CD40 ligand; EDN1; Endothelin 1; F3; coagulation factor III; Foxp3; Forkhead box protein 3; ICAM-1; Intercellular ad
Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair
Keywords: CDK4/6; cyclin-dependent kinases 4 and 6; CDK2; cyclin-dependent kinase 2; iCDK4/6; inhibitor of CDK4/6; LEE011; inhibitor of CDK4/6, ribociclib, Kisqali; PD0332991; inhibitor of CDK4/6, palbociclib, Imbrance; NU6140; cyclin-dependent kinase 2 (CDK2) inhi
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis
Keywords: mtDNA; Ogg1; Hyperglycemia; Fasting; DNA repair; Gluconeogenesis;
Studying protein-DNA interactions using atomic force microscopy
Keywords: AFM; atomic force microscopy; AGT; O6-alkylguanine DNA alkyltransferase; CPD; cyclobutane pyrimidine dimer; DREEM; dual-resonance-frequency-enhanced electrostatic force microscopy; EM; electron microscopy; EMSA; electrophoretic mobility shift assay; FRET;
OGG1 regulates the level of symmetric dimethylation of histone H4 arginine-3 by interacting with PRMT5
Keywords: OGG1; PRMT5; H4R3me2s; Arginine methylation;
8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions
Keywords: ROS; reactive oxygen species; 8-oxoG; 7, 8-dihydro-8-oxoguanine; OGG1; 8-oxoguanine DNA glycosylase 1; BER; base excision repair; OGG1-BER; OGG1-initiated DNA base excision repair; IIR; innate immune response; TNFα; Tumor necrosis factor alpha; NF-κB; N
An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma
Keywords: ROS; reactive oxygen species; 8-oxodGuo; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; 8-oxoguanine or GO; 8-oxo-7,8-dihydroguanine; OGG1; 8-oxoguanine DNA glycosylase protein; CI; confidence interval; HR; hazard ratio; SNP; single nucleotide polymorphism; ROS;
Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA
Keywords: mtDNA; OGG1; ALKBH7; DNA modification; Metabolism;
Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy
Keywords: ROS; reactive oxygen species; 8-oxoGua; 8-Oxo-7,8-dihydroguanine; UNG; uracil-DNA glycosylase; TET; ten-eleven translocation protein; 5-mCyt; 5-Methylcytosine; 5-hmCyt; 5-Hydroxymethylcytosine; 5-fCyt; 5-formylcytosine; 5-caCyt; 5-Carboxycytosine; BER; ba
The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation
Keywords: ROS; reactive oxygen species; AP; apurinic/apyrimidinic site; THF; 3-hydroxy-2-hydroxymethyltetrahydrofuran or tetrahydrofuran; Ura; uracil; dU; 2â²-deoxyuridine; αdA; α-anomeric 2â²-deoxyadenosine; Hx; hypoxanthine; 8oxoG; 7,8-dihydro-8-oxoguanine; B
Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes
Keywords: Oxidatively generated DNA damage; Base excision repair; OGG1; LSD1/KDM1A; Regulation of transcription;
MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?
Keywords: Reactive oxygen species; 8-oxo-7, 8-dihydroguanine; 8-oxo-dGTP; Base excision repair; OGG1; MUTYH; Carcinogenesis; Neurodegeneration;
Oxidatively generated base modifications in DNA: Not only carcinogenic risk factor but also regulatory mark?
Keywords: Oxidatively generated DNA damage; Base excision repair; OGG1; LSD1; Regulation of transcription;
DNA repair and systemic lupus erythematosus
Keywords: 8-oxoG; 8-hydroxyguanosine; OGG1; 8-oxoguanine DNA glycosylase; ARTD1; ADP-ribosyltransferase diphtheria toxin-like 1; ATM; Ataxia telangiectasia mutated; BER; base excision repair; BMDMs; bone marrow-derived macrophages; CSR; lass switch recombination; C
Chromatin associated mechanisms in base excision repair - nucleosome remodeling and DNA transcription, two key players
Keywords: DNA oxidative damage; Base excision repair; OGG1; 8-oxoG; Transcription coupled repair; Nucleosome; Chromatin; Chromatin remodeling;
8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging
Keywords: 8-oxoG; 7,8-dihydro-8-oxoguanine; 8-oxodG; 7,8-dihydro-8-oxo-2â²-deoxyguanosine; BER; base excision repair; DNA dsbs; double strand breaks; DNA ssbs; single strand breaks; GEF; guanine nucleotide exchange factor; GOrilla; Gene Ontology enrichment analysi
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways
Keywords: D-gal; D-galactose; H2S; Hydrogen Sulfide; ROS; Reactive Oxygen Species; CD; Common Deletion; GSH; Glutathione; SOD; Superoxide Dismutase; DMEM; Dulbecco's Modified Eagle Medium; PI3K; Phosphatidylinositol 3-kinase; CaMKKβ; Ca2+/calmodulin-dependent prot
Methylation analysis of DNA repair genes in Alzheimer's disease
Keywords: DNA methylation; Alzheimer's disease; Epigenetics; DNA repair; OGG1; PARP1 BRCA1; MGMT; MLH1; MRE11A;
Repair of 8-oxo-7,8-dihydroguanine in prokaryotic and eukaryotic cells: Properties and biological roles of the Fpg and OGG1 DNA N-glycosylases
Keywords: Base excision repair; 8-oxoguanine; 8-oxoguanine-DNA glycosylases; Fpg; OGG1; GO repair network; Spontaneous mutations; Therapeutic targets cancer;
Not breathing is not an option: How to deal with oxidative DNA damage
Keywords: OGG1; MUTYH; DNA polymerase β; DNA polymerase λ; DNA polymerase δ; 8-oxo-G; 8-oxoG; DNA polymerase switch; Oxidative stress; Cancer;
Anti-inflammatory effect of strawberry extract against LPS-induced stress in RAW 264.7 macrophages
Keywords: Strawberry; Phenolic compounds; LPS; Inflammation; ROS; Prevention; 2,4 DNP; 2,4-Dinitrophenol; ACYs; anthocyanins; ARE; antioxidant responsive element; CDNB; 1-chloro-2,4-dinitro benzene; DMEM; Dulbecco's Modified Eagle Medium; DPPH; 2,2-DiPhenyl-1-Picry
XPC deficiency is related to APE1 and OGG1 expression and function
Keywords: Oxidative stress; XPC; APE1; OGG1; DNA damage; DNA repair
Potential role of 8-oxoguanine DNA glycosylase 1 as a STAT1 coactivator in endotoxin-induced inflammatory response
Keywords: BER; base excision repair; ChIP; chromatin immunoprecipitation; COX-2; cyclooxygenase-2; EAE; experimental autoimmune encephalomyelitis; faPyG; 2,6-diamino-4-hydroxy-5-formamidopyrimidine; GAS; gamma-interferon activation site; iNOS; inducible nitric oxid
Micronome revealed miR-19a/b as key regulator of SOCS3 during cancer related inflammation of oral squamous cell carcinoma
Keywords: OSCC; Oral Squamous Cell Carcinoma; miRNA; MicroRNA; NGS; Next Generation Sequencing; STRING; Search Tool for Retrieval of Interacting Genes/Proteins; ACTREC; Advanced Centre for Treatment Research and Education in Cancer; HNOCDB; Head Neck Oral Cancer Da
Role of XPD in cellular functions: To TFIIH and beyond
Keywords: ANT2; an adenine nucleotide translocase that exchanges mitochondrial ATP with cytosolic ADP; CDK; cyclin dependent kinase; CAK; CDK-activating kinase complex; CIA; cytoplasmic FeS assembly; CIA01/2; cytosolic iron-sulfur assembly component ½; CS; Cockayn
Pathways controlling dNTP pools to maintain genome stability
Keywords: BER; base excision repair; CDA; cytidine deaminase; MMR; mis-match repair; MTH; MutT homologue; MUTYH; MutY homologue; Nudix; nucleoside diphosphate linked to some other moiety, X; NUDT; Nudix-type; OGG1; 8-oxoguanine glycosylase; ROS; reactive oxygen spe
OGG1 is essential in oxidative stress induced DNA demethylation
Keywords: OGG1; 8-Oxoguanine DNA glycosylase-1; 8-oxoG; 8-Oxoguanine; ROS; reactive oxygen species; α-KG; α-Ketoglutarate; MeDIP; methylated DNA immunoprecipitations; 5mC; 5-Methyl cytosine; 5hmC; 5-Hydroxymethyl cytosine; 5fC; 5-Formylcytosine; 5caC; 5-Carboxylc
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Keywords: BER; base excision repair; DFCS; disease-free carotid segments; MI; myocardial infarction; ROS; reactive oxygen species; TDG; thymine DNA glycosylase; OGG1; 8-oxoguanine DNA glycosylase 1; NTH; Nth-like DNA glycosylase 1; SMUG1; single-strand-selective mo
Suppression of human 8-oxoguanine DNA glycosylase (OGG1) augments ultrasound-induced apoptosis in cervical cancer cells
Keywords: OGG1; Ultrasound; Cervical cancer cells; Apoptosis; Reactive oxygen species;
The impact of detoxifying and repair gene polymorphisms and the levels of serum ROS in the susceptibility to multiple sclerosis
Keywords: Multiple sclerosis; GSTs; XRCC1; OGG1; Polymorphism; Reactive oxygen species
Nrf2 promotes survival following exposure to ionizing radiation
Keywords: ARE; antioxidant response element; ARS; acute radiation syndrome; ATM; ataxia telangiectasia mutated; BRCA1; breast cancer type 1 susceptibility protein; ChIP; chromatin immunoprecipitation; CnC; cap 'n׳ collar family of basic leucine zipper transcript
Dynamic regulation of cerebral DNA repair genes by psychological stress
Keywords: HPA-axis; Hypothalamic-pituitary-adrenal axis; ROS; reactive oxygen species; BER; base excision repair; NER; nucleotide excision repair; SSBR; single strand break repair; Ogg1; 8-oxoguanine glycosylase 1; Neil1; endonuclease VIII-like 1; Ung1; uracil DNA
BRCA1: Beyond double-strand break repair
Keywords: BRCA1; Base-excision repair; 8oxoG; 8-oxo-guanine; 8oxodG; 8-hydroxy-2â²-deoxyguanosine; AP; apurinic/apyrimidinic; APE1 (or APE1/REF1); AP-endonuclease (redox effector factor-1); ATR; ataxia telangiectasia and Rad3 related; ATM; ataxia telangiectasia mu
The repair of oxidized purines in the DNA of human lymphocytes requires an activation involving NF-YA-mediated upregulation of OGG1
Keywords: Oxidatively generated DNA damage; Base excision repair; OGG1; NF-YA; Phytohemagglutinin;
Mitochondrial OGG1 protects against PM2.5-induced oxidative DNA damage in BEAS-2B cells
Keywords: OGG1; PM2.5; MMP; ROS; mtDNAcn