دانلود مقالات ISI درباره P-gp، P-glycoprotein + ترجمه فارسی

عوامل ضد میکرووبولول: کشف جدید مواد مخدر و درمان سرطان

Microtubule-stabilizing agents: New drug discovery and cancer therapy

Keywords: P-gp، P-glycoprotein; Microtubule-stabilizing agent; Paclitaxel; Epothilone; Cancer therapy; Natural productMDA, Microtubule-destabilizing agent; MDR, Multidrug resistance; MSA, Microtubule-stabilizing agent; P-gp, P-glycoprotein; SAR, Structure–activity relationship

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

طراحی، سنتز و ارزیابی بیولوژیکی یک سری جدید از مهار کننده های جذب نورآدرنالین محیطی انتخابی بخش 2

Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors—Part 2

Keywords: P-gp، P-glycoprotein; SUI, stress urinary incontinence; DAT, dopamine transporter; SERT, serotonin transporter; NET, norepinephrine transporter; MDR1, multidrug resistance 1; P-gp, P-glycoprotein; CYP, cytochrome P450; hERG, human ether-a-go-go-related gene K+ channel; CNS, ce

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

حمل کننده های مواد مخدر نقش کلیدی در روند پیچیده مقاومت به ایماتینیب در آزمایشگاهی دارند

Drug transporters play a key role in the complex process of Imatinib resistance in vitro

Keywords: P-gp، P-glycoprotein; BCRP, breast cancer related protein; CML, chronic myeloid leukemia; IMA, Imatinib; P-gP, P-glycoprotein; OCT, organic cation transporter; TKI, tirosine kinase inhibitorCML; Imatinib resistance; Therapeutic interruptions; Membrane drug transporters; P-glyc

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

فعالیت های متقاطع سیتوتوکسیک و چند داروی جدید تغییر رژیم 1،4-دی هیدروپیریدین علیه سلول های سرطانی انسان

Cytotoxic and multidrug resistance reversal activities of novel 1,4-dihydropyridines against human cancer cells

Keywords: P-gp، P-glycoprotein; ABC, ATP-binding cassette; MDR, multidrug resistance; P-gp, P-glycoprotein; DHP, dihydropyridine; CCB, calcium channel blocking; MTT, thiazolyl blue tetrazolium bromide; Rh123, rhodamine 123.1,4-Dihydropyridine (CID 104822); Multidrug resistance; Cytotoxi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

اثر مهاری از وستراتسان بر جذب روده و دفع کلیوی فراستین در موش صحرایی

Inhibitory Effect of Valsartan on the Intestinal Absorption and Renal Excretion of Bestatin in Rats

Keywords: P-gp، P-glycoprotein; pharamcokinetics; drug interaction; intestinal absorption; peptide transporters; renal excretion; organic anion transporters; DDIs, drug-drug interactions; PEPT, H+/peptide transporter; OAT, organic anion transporter; OCT, organic cation transporter; ACEI

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacokinetics and tissue distribution of 5,7-dimethoxyflavone in mice following single dose oral administration

Keywords: P-gp، P-glycoprotein; 5,7-DMF, 5,7-Dimethoxyflavone; PK, pharmacokinetic; LC–MS/MS, Liquid chromatography–tandem mass spectrometry; CYP, Cytochrome P450; P-gp, P-glycoprotein; MRP, multidrug resistance associated-proteins; BCRP, Breast Cancer Resistance Protein; MDR, multidrug

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells

Keywords: P-gp، P-glycoprotein; Pregnane X receptor; SUMOylation; Transcriptional activity; CYP3A4; P-gpSUMO, small ubiquitin-related modifier; PXR, pregnane X receptor; RIF, rifampicin; CYP3A4, cytochrome P450 3A4; P-gp, p-glycoprotein; MDZ, midazolam; 1′-OHMDZ, 1′-Hydroxymidazolam; Rh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Prediction and characterization of P-glycoprotein substrates potentially bound to different sites by emerging chemical pattern and hierarchical cluster analysis

Keywords: P-gp، P-glycoprotein; P-gp, P-glycoprotein; ABC, ATP-binding cassette; MDR, multidrug resistance; EP, emerging pattern; ECP, emerging chemical pattern; ECPG, emerging chemical pattern group; TM, transmembrane; TMD, transmembrane domain; NBD, nucleotide-binding domain; SBS, sub

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Supersaturation induced by Itraconazole/Soluplus® micelles provided high GI absorption in vivo

Keywords: P-gp، P-glycoprotein; Solid dispersion; Itraconazole tablets; Hot melt extrusion; Supersaturation; Micelles; BioavailabilityITZ, Itraconazole; HME, Hot melt extrusion; P-gp, P-glycoprotein; DSC, differential scanning calorimetry; CMC, critical micelle concentration; GPC, Gel P

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2

Keywords: P-gp، P-glycoprotein; ABC transporters; ABCC2 inhibitors; Indolylmethylenebenzofuranone; Aurones; Drug interactionsABCC2, second member of the C subfamily of the ABC pumps; DDI, drug-drug interactions; P-gp, P-glycoprotein; MRP, multidrug resistance protein; BCRP, breast cance

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines

Keywords: P-gp، P-glycoprotein; ALDH1A1, Aldehyde dehydrogenase 1A1; P-gp, P-glycoprotein; BCRP, breast cancer resistance protein; ATRA, all-trans retinoic acid; DEAB, diethylaminobenzoaldehyde; PAC, paclitaxel; TOP, topotecan; CIS, cisplatin; DOX, doxorubicin; MDR, multiple drug resist

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

P-glycoprotein Mediates Ceritinib Resistance in Anaplastic Lymphoma Kinase-rearranged Non-small Cell Lung Cancer

Keywords: P-gp، P-glycoprotein; ALK, anaplastic lymphoma kinase; TKI, tyrosine kinase inhibitor; P-gp, P-glycoprotein; ROS1, v-ros avian ur2 sarcoma virus oncogene homolog 1; PFS, progression-free survival; ORR, overall response rate; EGFR, epidermal growth factor receptor; BBB, blood–b

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Selenate specifically sensitizes drug-resistant cancer cells by increasing apoptosis via G2 phase cell cycle arrest without P-GP inhibition

Keywords: P-gp، P-glycoprotein; VIC, Vincristine; VER, Verapamil; P-gp, p-glycoprotein; DMSO, Dimethylsulfoxide; FACS, Fluorescence-activated cell sorting; FBS, Fetal bovine serum; TCA, Trichloroacetic a

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Association of ABCB1/MDR1 polymorphisms in patients with glucocorticoid-induced osteonecrosis of the femoral head: Evidence for a meta-analysis

Keywords: P-gp، P-glycoprotein; GC-induced ONFH, glucocorticoid-induced osteonecrosis of the femoral head; P-gp, P-glycoprotein; SNPs, single nucleotide polymorphisms; OR, odds ratio; CI, confidence interval.Glucocorticoid; Osteonecrosis; ATP-binding cassette sub-family B; Polymorphism;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

TPGS-chitosome as an effective oral delivery system for improving the bioavailability of Coenzyme Q10

Keywords: P-gp، P-glycoprotein; CoQ10, Coenzyme Q10; chitosome, chitosan coated liposome; TPGS, d-alpha-tocopheryl polyethylene glycol 1000 succinate; TPGS-chitosome, chitosan and TPGS coated liposome; GI, gastrointestinal; P-gp, P-glycoprotein; MLV, multilamellar vesicles; UPLC, ultra

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice

Keywords: P-gp، P-glycoprotein; Acetaminophen; ABC transporters; Brain; Nrf2ALT, alanine aminotransferase; P-gp, P-glycoprotein; APAP, acetaminophen; R123, Rhodamine 123; Mrp, multidrug resistance-associated protein; ANOVA, analysis of variance; Ho-1, heme oxygenase; Keap1, Kelch-like E

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Decreased expression of nucleophosmin/B23 increases drug sensitivity of adriamycin-resistant Molt-4 leukemia cells through mdr-1 regulation and Akt/mTOR signaling

Keywords: P-gp، P-glycoprotein; NPM/B23, nucleophosmin/B23; ALL, acute lymphoblastic leukemia; MDR, multidrug resistance; P-gp, P-glycoprotein; ADM, adriamycin; DNR, daunorubicin; CTX, cyclophosphamide; VCR, vincristine; VP16, etoposide; IC50, half inhibitory concentration; RNAi, RNA in

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Thioredoxin 1 upregulates FOXO1 transcriptional activity in drug resistance in ovarian cancer cells

Keywords: P-gp، P-glycoprotein; FOXO, forkhead box class O; Trx1, thioredoxin 1; P-gp, P-glycoprotein; PTX, paclitaxel; ROS, reactive oxygen species; DTNB, 5,5′-dithio-bis(2-nitrobenzioic) acid; H2DCF-DA, 2′,7′-dichlorodihydrofluorescein diacetate; HPLC, high performance liquid chromato

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Tissue accumulation and toxicity of isothiazolinone in Ctenopharyngodon idellus (grass carp): Association with P-glycoprotein expression and location within tissues

Keywords: P-gp، P-glycoprotein; C. idellus, Ctenopharyngodon idellus; P-gp, P-glycoprotein; ABC, ATP-binding cassette; LC50, median lethal concentration; HPLC, high performance liquid chromatography; RT-PCR, real-time polymerase chain reaction; MCI, methylchloroisothiazolinone; MCI/MI,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of blood–brain barrier and blood–cerebrospinal fluid barrier permeability of 2-phenoxy-indan-1-one derivatives using in vitro cell models

Keywords: P-gp، P-glycoprotein; PIOs, 2-phenoxy-indan-1-one derivatives; AD, Alzheimer's disease; CNS, central nervous system; BBB, blood–brain barrier; BCSFB, blood–cerebrospinal fluid barrier; MDCK, Madin–Darby canine kidney; P-gp, P-glycoprotein; MDR, multidrug resistance; CP, choroi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

SP600125 overcomes antimitotic drug-resistance in cancer cells by increasing apoptosis with independence of P-gp inhibition

Keywords: P-gp، P-glycoprotein; Jnk, c-Jun N-terminal kinase; S.D., Standard deviation; SP, SP600125; PAC, Paclitaxcel; DOC, Docetaxcel; VIB, Vinblastine; COL, Colchicine; DOX, Doxorubicin; MDR, Multi drug-resistance; P-gp, P-glycoprotein; DMSO, Dimethylsulfoxide; FACS, Fluorescence-act

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Aliskiren toxicity in juvenile rats is determined by ontogenic regulation of intestinal P-glycoprotein expression

Keywords: P-gp، P-glycoprotein; MDR1, multidrug-resistant protein 1; NOAEL, no observable adverse effect level; OATP, organic anion transporting polypeptide; P-gp, P-glycoprotein; PPD, postpartum dayAliskiren; Juvenile rat; Toxicity; Exposure; MDR1; OATP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Kinetic Analysis of Rhodamines Efflux Mediated by the Multidrug Resistance Protein (MRP1)

Keywords: P-gp، P-glycoprotein; MRP1, multidrug resistance associated protein; P-gp, P-glycoprotein; MDR, multidrug resistance; Rh 6G, Rhodamine 6G; TMR, tetramethylrosamine; Rh I, tetramethylrhodamine ethyl ester or rhodamine I; Rh II, tetramethylrhodamine methyl ester or rhodamine II;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative evaluation of two dye probes in the rat everted gut sac model for unambiguous classification of P-gp substrate and inhibitor

Keywords: P-gp، P-glycoprotein; Ab, beta-amyloid; Ab-HiLyte, HiLyte Fluor™ TR-labeled; AD, Alzheimer's disease; BBB, blood–brain barrier; MDR, multidrug resistance; P-gp, P-glycoprotein; Rho, rhodamine 123Beta-amyloid; Rat everted gut sac assay; P-glycoprotein; MC18; MC266; HiLyte Fluor

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Placental P-glycoprotein is unaffected by timing of antenatal glucocorticoid therapy but reduced in SGA preterm infants

Keywords: P-gp، P-glycoprotein; P glycoprotein; Placenta; Preterm neonate; Antenatal steroids; SGA; Placental glucocorticoid barrierSGA, small for gestational age; AGA, appropriate for gestational age; P-gp, P-glycoprotein; 11βHSD2, 11 beta hydroxysteroid dehydrogenase; CRIB, clinical r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

In vivo effect of Schisandrin B on cytochrome P450 enzyme activity

Keywords: P-gp، P-glycoprotein; Sch A, Schisandrin A; Sch B, Schisandrin B; SchE, Schisandra sphenanthera extract; P-gp, P-glycoprotein; MDR, multidrug resistance; CYP, cytochrome P450; CYP3A, cytochrome P450 3A; CYP3A4, cytochrome P450 3A4; IC50, the half maximal (50%) inhibitory conce

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Influence of CYP3A4, CYP3A5 and MDR-1 polymorphisms on tacrolimus pharmacokinetics and early renal dysfunction in liver transplant recipients

Keywords: P-gp، P-glycoprotein; CYP450, cytochrome P450 enzymes; MDR, multidrug resistance; P-gp, P-glycoprotein; C/D ratio, tacrolimus concentration/dose ratio; ALT, alanine aminotransferase; ALP, alkaline phosphatase; CNI, calcineurin inhibitor; MA, microalbumin; IGU, urine immunoglob

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro characterization of ABC transporters involved in the absorption and distribution of liensinine and its analogs

Keywords: P-gp، P-glycoprotein; MDR1, reverse multidrug resistance 1; P-gp, P-glycoprotein; MRP2, MDR-associated protein 2; GF120918, N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide; CsA, cyclosporin A; Calcein

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Quantification of cabazitaxel, its metabolite docetaxel and the determination of the demethylated metabolites RPR112698 and RPR123142 as docetaxel equivalents in human plasma by liquid chromatography–tandem mass spectrometry

Keywords: P-gp، P-glycoprotein; P-gp, P-glycoprotein; mCRPC, metastasized castration resistant prostate cancer; Cmax, maximum plasma concentration; ACN, acetonitrile; TBME, tert-butyl methyl ether; IS, internal standard; AT-IS, 2′,7-bisacetyltaxol; DOC-IS, docetaxel-d9; ESI, electrospra

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Overcoming multidrug resistance using liposomal epirubicin and antisense oligonucleotides targeting pump and nonpump resistances in vitro and in vivo

Keywords: P-gp، P-glycoprotein; Multidrug resistance; Antisense oligonucleotides; EpirubicinMDR, multidrug resistance; P-gp, P-glycoprotein; MRPs, MDR-associated proteins; ASOs, antisense oligonucleotides; Epi, epirubicin; CT26, mouse colon adenocarcinoma cells; PEGylated, polyethylene

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Contribution of TRPV1 and multidrug resistance proteins in the permeation of capsaicin across different intestinal regions

Keywords: P-gp، P-glycoprotein; TRPV1, transient receptor potential cation channel; BCRP, breast cancer resistance protein; MRP2, multidrug resistance-associated protein 2; P-gp, P-glycoprotein; RR, ruthenium red; Na-Flu, Na-fluoresceinCapsaicin; Intestinal permeability; Regional differ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

In vivo disposition and metabolism of madecassoside, a major bioactive constituent in Centella asiatica (L.) Urb.

Keywords: P-gp، P-glycoprotein; IS, Internal standard; P-gp, P-glycoprotein; MRP2, Multidrug resistance-associated protein; LC-TOF-MS, Liquid chromatography coupled with time-of-flight mass spectrometry; LLOQ, Lower limit of quantification; QC, Quality controlMadecassoside; Tissue distr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Biopharmaceutical classification of poorly soluble drugs with respect to “enabling formulations”

Keywords: P-gp، P-glycoprotein; BCS, Biopharmaceutical Classification Scheme; GI, Gastrointestinal; p-GP, p-Glycoprotein; MRP, multidrug resistance-related protein; BCRP, breast cancer resistant protein; CMC, critical micelle concentration; CsA, cyclosporin A; TEER, transepithelial elec

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters

Keywords: P-gp، P-glycoprotein; MDR, MultiDrug Resistance; ABC, ATP Binding Cassette; P-gp, P-glycoprotein; BCRP, Breast Cancer Resistance Protein; MRP1, MultiDrug Resistance-associated Protein1; Papp, apparent permeability; Calcein-AM, Acetoxymethyl esters of calcein; MDCK, Madin-Darby

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin

Keywords: P-gp، P-glycoprotein; P-gp; Bestatin; Intestinal absorption; Antiproliferative activityDDI, drug–drug interaction; P-gp, P-glycoprotein; PEPT, H+/peptide transporter; OAT, organic anion transporter; OCT, organic cation transporter; MRP2, multidrug resistance-associated protein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein

Keywords: P-gp، P-glycoprotein; HMs, herbal medicines; P-gp, P-glycoprotein; SLE, Schisandra lignans extract; DDI, drug–drug interaction; TBS-T, Tris-buffered saline-Tween 20; AP, apical; BL, basolateral; HBSS, Hank's balanced salt solution; AUC, the area under the concentration–time cu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53

Keywords: P-gp، P-glycoprotein; Colorectal cancer; Ceramide; C6-ceramide; Tamoxifen; P-glycoprotein; p53CRC, colorectal cancer; P-gp, P-glycoprotein; GCS, glucosylceramide synthase; GC, glucosylceramide; PARP, poly ADP ribose polymerase; MMP, mitochondrial membrane permeabilization; FBS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Liquorice, a unique “guide drug” of traditional Chinese medicine: A review of its role in drug interactions

Keywords: P-gp، P-glycoprotein; CYP, cytochrome; DGLL, diammonium glycyrrhizinate lipid ligand; GA, glycyrrhetic acid; GZ, glycyrrhizin; HSYA, hydroxysafflor yellow A; IC50, half maximal inhibitory concentration; P-gp, P-glycoprotein; TCM, traditional Chinese medicineLiquorice; Cytochro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Berberine analogue IMB-Y53 improves glucose-lowering efficacy by averting cellular efflux especially P-glycoprotein efflux

Keywords: P-gp، P-glycoprotein; P-gp, P-glycoprotein; MDR, multidrug resistance; MRP, multidrug resistance-associated protein; BBR, Berberine; LDLR, low-density-lipoprotein receptor; InsR, insulin receptor; AMPK, AMP-activated protein kinase; IMB-Y53, pseudo-berberine; Tet, tetrandrine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

The effect of ABCB1 C3435T polymorphism on pharmacokinetics of tacrolimus in liver transplantation: A meta-analysis

Keywords: P-gp، P-glycoprotein; CI, confidence intervals; P-gp, P-glycoprotein; SNPs, single nucleotide polymorphisms; WMD, weighted mean differencesMeta-analysis; Association; ABCB1 C3435T; Polymorphism; Tacrolimus pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

The elimination of P-glycoprotein over-expressing cancer cells by antimicrobial cationic peptide NK-2: The unique way of multi-drug resistance modulation

Keywords: P-gp، P-glycoprotein; NK-2, NK-lysin derived peptide; NK11, inactive form of NK-2; PS, phosphatidylserine; MDR, multi-drug resistance; P-gp, P-glycoprotein; AMP, antimicrobial peptide; Dex-VER, R+Verapamil; TQ, tariquidar; PI, propidium iodide; MTT, 3-(4,5-dimethyl-2-thizolyl)

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Modulation of efflux proteins by electromagnetic field for delivering azidothymidine and saquinavir into the brain

Keywords: P-gp، P-glycoprotein; AZT, azidothymidine; BBB, blood–brain barrier; EMF, electromagnetic field; HA, human astrocyte; HBMEC, human brain-microvascular endothelial cell; MRP, multidrug resistance-associated protein; P-gp, P-glycoprotein; SAR, specific absorption rate; SQV, saqu

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The associations of IL-18 serum levels and promoter polymorphism with tacrolimus pharmacokinetics and hepatic allograft dysfunction in Chinese liver transplantation recipients

Keywords: P-gp، P-glycoprotein; IL-18, Interleukin 18; CYP450, cytochrome P450 enzymes; MDR, The multidrug resistance; P-gp, P-glycoprotein; TNF-α, tumor necrosis factor-α; C/D ratio, tacrolimus concentration/dose ratio; ALT, alanine aminotransferase; ALP, alkaline phosphatase; CNI, cal

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Meta-analysis of the effect of MDR1 C3435 polymorphism on tacrolimus pharmacokinetics in renal transplant recipients

Keywords: P-gp، P-glycoprotein; ABCB1, ATP binding cassette subfamily B, member 1; CYP3A, cytochrome P450 3A; P-gp, P-glycoprotein; OR, odds ratio; CI, confidence intervalRenal transplantation; Tacrolimus pharmacokinetics; Polymorphism; MDR1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Mixed micelles of PEG2000-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: Enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines

Keywords: P-gp، P-glycoprotein; NSCLC, non-small cell lung cancer; P-gp, P-glycoprotein; vitamin E-TPGS, vitamin E-d-alpha tocopheryl polyethyleneglycol succinate; A549, adenocarcinomic human alveolar basal epithelial cells; NF-κB, nuclear factor kappa-light-chain-enhancer of activated

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

(5R)-5-hydroxytriptolide (LLDT-8), a novel immunosuppressant in clinical trials, exhibits potent antitumor activity via transcription inhibition

Keywords: P-gp، P-glycoprotein; LLDT-8, (5R)-5-hydroxytriptolide); MDR, multidrug-resistance; P-gp, P-glycoprotein; BrU, 5-bromouridine; HSP70, heat-shock protein 70(5R)-5-hydroxytriptolide; Triptolide; Transcription inhibition

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line

Keywords: P-gp، P-glycoprotein; ABC, ATP-binding cassette; AhR, aryl-hydrocarbon receptor; CAR, constitutive androstane receptor; IVM, ivermectin; MLs, macrocyclic lactones; P-gp, P-glycoprotein; PXR, pregnane X receptorIvermectin; Macrocyclic lactones; P-glycoprotein; Mdr1; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

7,3′,4′-Trihydroxyisoflavone modulates multidrug resistance transporters and induces apoptosis via production of reactive oxygen species

Keywords: P-gp، P-glycoprotein; 7,3′,4′-THIF, 7,3′,4′-trihydroxyisoflavone; MDR, multidrug resistance; P-gp, P-glycoprotein; MRPs, MDR-associated proteins; ROS, reactive oxygen species; Epi, epirubicin; HeLa, human cervical cancer cells; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl te

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging inorganic nanomaterials for pancreatic cancer diagnosis and treatment

Keywords: P-gp، P-glycoprotein; MDR, multidrug resistance; P-gp, P-glycoprotein; CSCs, cancer stem cells; SPIONs, super-paramagnetic iron oxide nanoparticles; CNTs, carbon nanotubes; SWNTs, single-walled carbon nanotubes; MWNTs, multi-walled carbon nanotubes; siRNA, small interfering RN

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Relation between 3435C>T multidrug resistance 1 gene polymorphism with high dose methylprednisolone treatment of childhood acute idiopathic thrombocytopenic purpura

Keywords: P-gp، P-glycoprotein; HDMP, High dose methylprednisolone; ITP, Idiopathic thrombocytopenic purpura; MDR-1, Multidrug resistance-1; P-gp, P-glycoprotein; SNPs, Single nucleotide polymorphisms; IVIG, Intravenous immune globulin; R, response; NR, No responseMDR1; Idiopathic throm

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه