A BTB-ZF protein, ZNF131, is required for early B cell development
Keywords: ZNF131; BTB-ZF; pro-B cell; Immunoglobulin gene rearrangement; Proliferation; p21cip1;
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SNAP23 suppresses cervical cancer progression via modulating the cell cycle
Keywords: CC; cervical cancer; IHC; immunohistochemistry; qRT-PCR; quantitive real time polymerase chain reaction; TMAs; tissue microarrays; Cervical cancer; SNAP23; p21cip1; CyclinB1;
p27Kip1 and p21Cip1-independent proliferative inhibition of vascular smooth muscle cells cultured in type-I collagen matrix honeycombs
Keywords: Smooth muscle cell; p27Kip1; p21Cip1; Three-dimensional culture;
Effects of a novel carbocyclic analog of pyrrolo[2,3-d]pyrimidine nucleoside on pleiotropic induction of cell death in prostate cancer cells with different androgen responsiveness
Keywords: Pyrrolo[2,3-d]pyrimidine; Prostate cancer; Apoptosis; Autophagy; p21Cip1; Androgen
PRMT7 Preserves Satellite Cell Regenerative Capacity
Keywords: PRMT7; muscle regeneration; senescence; aging; DNMT3b; p21CIP1; muscle stem cell
BH3-mimetic gossypol-induced autophagic cell death in mutant BRAF melanoma cells with high expression of p21Cip1
Keywords: Gossypol; BRAF inhibitor-resistance; Melanoma; Autophagy; p21Cip1
Immunohistochemical cellular distribution of proteins related to M phase regulation in early proliferative lesions induced by tumor promotion in rat two-stage carcinogenesis models
Keywords: Carcinogen; M phase; p21Cip1; Two-stage carcinogenesis model; Rat
Antitumor properties of substituted (αE)-α-(1H-indol-3-ylmethylene)benzeneacetic acids or amides
Keywords: Prostate cancer; Indoles; Perkin-Oglialoro reaction; Retinoblastoma protein; p21Cip1; DU145 cell line; DFT; VolSurf+;
Progestin drives breast cancer growth by inducing p21CIP1 expression through the assembly of a transcriptional complex among Stat3, progesterone receptor and ErbB-2
Keywords: PR; progesterone receptor; MPA; medroxy progesterone acetate; CdK; cyclin dependent kinase; PREs; progesterone response elements; Stat3; signal transducer and activator of transcription 3; GAS; gamma interferon-activated sequence; siRNAs; small interferen
DACH1 regulates cell cycle progression of myeloid cells through the control of cyclin D, Cdk 4/6 and p21Cip1
Keywords: DACH1; Myeloid leukemia; CCND; p21Cip1; MLL-AF9
CDK2 differentially controls normal cell senescence and cancer cell proliferation upon exposure to reactive oxygen species
Keywords: ROS, reactive oxygen species; CDK, cyclin-dependent kinase; PCNA, proliferating cell nuclear antigen; FACS, fluorescence-activated cell sorter; BrdU, 5-bromo-2′-deoxyuridine; PI, propidium iodideH2O2; CDK2; PCNA; p21Cip1; Senescence; Proliferation
BAG2 is a target of the c-Myc gene and is involved in cellular senescence via the p21CIP1 pathway
Keywords: BAG2; c-Myc; Senescence; SP1; p21CIP1
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and
Conditional ablation of the Notch2 receptor in the ocular lens
Keywords: Notch2; Lens fiber cell differentiation; Lens development; Jag1; p21Cip1
p21Cip1 regulates cell–substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells
Keywords: CDKN1A; p21Cip1; Focal adhesion; Microtubule; HDAC6; Mammary epithelial cells; Breast cancer
A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding
Keywords: Cyclin-dependent kinase; cdk; PSTAIRE; p21Cip1; p27Kip1; cdc28;
Dose-dependent changes in cyclin D1 in response to 4-nitroquinoline 1-oxide-induced DNA damage
Keywords: DNA damage; Cyclin D1; p21CIP1; 4NQO; p53; Retinoblastoma protein
Obovatol from Magnolia obovata inhibits vascular smooth muscle cell proliferation and intimal hyperplasia by inducing p21Cip1
Keywords: Obovatol; Angioplasty; Restenosis; Vascular smooth muscle cell; Carotid arteries; p21Cip1;
JY0691, a newly synthesized obovatol derivative, inhibits cell cycle progression of rat aortic smooth muscle cells through up-regulation of p21cip1
Keywords: Obovatol derivative; Platelet-derived growth factor; Cell cycle arrest; p21cip1; Rat aortic smooth muscle cell
Senescence and immortality in hepatocellular carcinoma
Keywords: Liver cancer; Senescence; Telomeres; DNA damage; p53; p16INK4a; p21Cip1; Retinoblastoma; Cirrhosis; Hepatocytes; Telomerase reverse transcriptase
Role of polyamines in p53-dependent apoptosis of intestinal epithelial cells
Keywords: Camptothecin; ATR; Mdm2; DFMO; p21Cip1; Nutlin-3
Significance of the C-terminal globular domain and the extra tail of the calmodulin-like protein (Pinctada fucata) in subcellular localization and protein-protein interaction
Keywords: Pinctada fucata; Calmodulin; Calmodulin-like protein; p21Cip1; Nucleocytoplasmic trafficking; ERK;
Differential regulation of the cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1 by phosphorylation directed by the cyclin encoded by Murine Herpesvirus 68
Keywords: Herpesvirus; Cyclin; Cyclin-dependent kinase; cdk2; Cell cycle; Phosphorylation; p27Kip1; p21Cip1
T-type Ca2+ channel expression in human esophageal carcinomas: A functional role in proliferation
Keywords: T-type calcium channel; Esophageal cancer; Proliferation; p21CIP1
The role of p21cip1 in adaptation of CHO cells to suspension and protein-free culture
Keywords: p21cip1; Cell cycle; Proliferation; Anchorage-dependent; Apoptosis; Protein free
BMP2 and BMP6 control p57Kip2 expression and cell growth arrest/terminal differentiation in normal primary human epidermal keratinocytes
Keywords: Keratinocytes; BMP; MSX2; p57Kip2; p21Cip1; ÎNp63α; Growth arrest; Differentiation;
Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53
Keywords: ROS, reactive oxygen species; EC, endothelial cells; HMEC1, human dermal microvascular EC; CMEC, coronary microvascular ECNADPH oxidase; Endothelial cells; Cell cycle; p21cip1; p53; Apoptosis; ROS
A cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord
Keywords: Neurogenesis; Stem cells; Proliferation; Neural tube; Differentiation; Progenitor; Cyclin; p57Kip2; p27Kip1; p21Cip1
Structure-activity relationship between carboxylic acids and T cell cycle blockade
Keywords: n-Butyrate; Carboxylic acids; Histone deacetylase; p21cip1;
The vitamin-like dietary supplement para-aminobenzoic acid enhances the antitumor activity of ionizing radiation
Keywords: Para-aminobenzoic acid; P21CIP1; CDC25A; Apoptosis; Tumor growth;
Absence of p21CIP1, p27KIP1 and p57KIP2 methylation in MDS and AML
Keywords: p21CIP1; p27KIP1; p57KIP2; Methylation; MDS; AML; Quantitative real-time PCR;
Retinoic acid modulates the retinoblastoma protein during adipocyte terminal differentiation
Keywords: Adipogenesis; Retinoic acid; Cell cycle; Retinoblastoma protein; p21Cip1;
Benzo[a]pyrene, but Not 2,3,7,8-TCDD, Induces G2/M Cell Cycle Arrest, p21CIP1 and p53 Phosphorylation in Human Choriocarcinoma JEG-3 Cells: A Distinct Signaling Pathway
Keywords: Benzo[a]pyrene (BaP); 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD); Cell cycle arrest; JEG-3 cells; Choriocarcinoma cells; Placenta; Apoptosis; p21CIP1; p53-Phosphorylation; Vitamin E;
A putative human breast stem cell population is enriched for steroid receptor-positive cells
Keywords: E2; estradiol; ERα; estrogen receptorα; PR; progesterone receptor; Msi1; Musashi1; TDLU; terminal duct lobuloalveolar unit; 3H-dT; tritiated thymidine; BrdU; bromodeoxyuridine; SP; side population; DAB; diaminobenzidine; DAPI; 4â²,6-diamidino-2-phenyli