Emodin alleviates lung injury in rats with sepsis
Keywords: P38 MAPK; Sepsis; Lung injury; p38 MAPK; TNF-α; IL-6
مقالات ISI P38 MAPK (ترجمه نشده)
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Inhibitory gene expression of the Cav3.1 T-type calcium channel to improve neuronal injury induced by lidocaine hydrochloride
Keywords: P38 MAPK; Lidocaine hydrochloride (PubChem CID: 6314); Calcium ion (PubChem CID: 271); 2-(4-Amidinophenyl)−6-indolecarbamidine dihydrochloride (PubChem CID: 160166; Propidium iodide (PubChem CID: 104981)Cav3.1; p38 MAPK; Lidocaine hydrochloride; SH-SY5Y cells
Ligustrazine alleviates acute pancreatitis by accelerating acinar cell apoptosis at early phase via the suppression of p38 and Erk MAPK pathways
Keywords: P38 MAPK; Ligustrazine; Acute pancreatitis; Acinar cell; Apoptosis; Erk; p38 MAPK
Synthesized peptides 705–734 from hepatitis C virus E2 glycoprotein induce dendritic cell maturation by activating p38 MAPK signaling
Keywords: P38 MAPK; HCV E2-705-734 peptides; Dendritic cell; Maturation; Immune evasion; p38 MAPK
Anticancer activity of silver nanoparticles from Panax ginseng fresh leaves in human cancer cells
Keywords: P38 MAPK; Panax ginseng; Silver nanoparticles; Apoptosis; Cell migration; p38 MAPK;
CREB regulates TNF-α-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts
Keywords: P38 MAPK; Asthma; cAMP; CREB; GM-CSF; p38 MAPK; GM-CSF; granulocyte-macrophage colony-stimulating factor; BEC; bronchial epithelium cell; ASMC; airway smooth muscle cell; TNF-α; tumor necrosis factor alpha; MAPK; mitogen-activated protein kinase; cAMP; cyclic AMP;
Inhibition of p38 mitogen-activated protein kinase signaling reduces fibrosis and lipid accumulation after rotator cuff repair
Keywords: P38 MAPK; Basic Science Study; In Vivo Animal ModelFatty degeneration; myosteatosis; rotator cuff; fibrosis; atrophy; inflammation; p38 MAPK
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway
Keywords: P38 MAPK; CARMA3; P38 MAPK; NF-кB; Invasion; Migration; Apoptosis;
Research reportLeptomycin B ameliorates vasogenic edema formation induced by status epilepticus via inhibiting p38 MAPK/VEGF pathway
Keywords: P38 MAPK; Epilepsy; Seizure; Leptomycin B; P38 MAPK; VEGF; Piriform cortex;
The “adaptive responses” of low concentrations of HBCD in L02 cells and the underlying molecular mechanisms
Keywords: P38 MAPK; HBCD; PI3K/Akt pathway; AMPK; p38 MAPK; L02 cells;
Anti-hepatitis B virus effect of matrine-type alkaloid and involvement of p38 mitogen-activated protein kinase and tumor necrosis factor receptor-associated factor 6
Keywords: P38 MAPK; HBV; hepatitis B virus; CHB; chronic hepatitis B; NAs; nucleoside and nucleotide analogues; p38 MAPK; p38 mitogen-activated protein kinase; TRAF6; tumor necrosis factor receptor-associated factor 6; ERK; extracellular signal-regulated kinase; HBsAg; hepat
Steroid receptor RNA activator: Biologic function and role in disease
Keywords: P38 MAPK; AF-2; activation function-2; AR; androgen receptor; C/EBPα; ccaat-enhancer-binding protein α; CTCF; CCCTC-binding factor; Ddx5; DEAD box protein 5; ERα; estrogen receptor α; GR; glucocorticoid receptor; Hes1; hairy and enhancer of split-1; HP1γ; hete
MTUS1 silencing promotes E-selectin production through p38 MAPK-dependent CREB ubiquitination in endothelial cells
Keywords: P38 MAPK; MTUS1; Endothelial cells; E-selectin; CREB; p38 MAPK;
PKG-1α mediates GATA4 transcriptional activity
Keywords: P38 MAPK; GATA4; GATA binding protein 4; NPPA; natriuretic peptide A; NPPB; natriuretic peptide B; MHC; myosin heavy chain; ERK; extracellular regulated protein kinases; p38 MAPK; p38 mitogen-activated protein kinases; PKC; protein kinase C; GSK 3β; glycogen synth
Slack sodium-activated potassium channel membrane expression requires p38 mitogen-activated protein kinase phosphorylation
Keywords: P38 MAPK; p38 MAPK; Slack; Phosphorylation; Regulation; DRG neurons; Membrane expression; MAPK; Mitogen-Activated Protein Kinase; DRG; Dorsal Root Ganglion; KNa; Sodium-activated Potassium Channel; INa; Sodium Current; TRPV1; Transient Receptor Potential Cation Cha
Iridoid glycoside from Cornus officinalis ameliorated diabetes mellitus-induced testicular damage in male rats: Involvement of suppression of the AGEs/RAGE/p38 MAPK signaling pathway
Keywords: P38 MAPK; Cornus officinalis; Iridoid glycoside; Diabetic testicular damage; Advanced glycation end-products; P38 MAPK;
Induction of cytokines via NF-κB and p38 MAP kinase signalling pathways associated with the immunomodulation by Lactobacillus plantarum NDC 75017 in vitro and in vivo
Keywords: P38 MAPK; Cytokines; Intestinal epithelium cells; Lactobacillus plantarum; Immunomodulatory effects; NF-κB; p38 MAPK; Interleukin-1beta (PubChem CID: 123871); NF-κB Activation Inhibitor (PubChem CID: 123871); SB 203580 hydrochloride (PubChem CID: 1676044);
Molecular basis and functional significance of Angiotensin II-induced increase in Discoidin Domain Receptor 2 gene expression in cardiac fibroblasts
Keywords: P38 MAPK; Cardiac fibroblasts; Discoidin domain receptor 2; Angiotensin II; NF-κB; p38 MAPK; Collagen type I;
AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway
Keywords: P38 MAPK; AGR2; p53; p38 MAPK; DUSP10; Drug resistance; Breast cancer;
Impact of PAMAM delivery systems on signal transduction pathways in vivo: Modulation of ERK1/2 and p38 MAP kinase signaling in the normal and diabetic kidney
Keywords: P38 MAPK; EGFR; epidermal growth factor receptor; ERK1/2; extracellular-regulated kinase 1/2; p38 MAPK; p38 mitogen-activated protein kinase; PAMAM; polyamidoamine; PF; Polyfect; SF; Superfect; STZ; streptozotocin; PAMAM; Dendrimer delivery system; ERK1/2; p38 MAPK
Cynanchum wilfordii Radix attenuates liver fat accumulation and damage by suppressing hepatic cyclooxygenase-2 and mitogen-activated protein kinase in mice fed with a high-fat and high-fructose diet
Keywords: P38 MAPK; Cynanchum wilfordii; Cyclooxygenase-2; Hepatic inflammation; Nonalcoholic fatty liver disease; p38 MAPK; Nuclear factor κBCOX-2, cyclooxygenase-2; ATHFR, atherogenic diet with fructose; DTT, dithiothreitol; GOT, glutamic oxaloacetic transaminase; GPT, glu
A novel p38 MAPK indentified from Crassostrea hongkongensis and its involvement in host response to immune challenges
Keywords: P38 MAPK; Crassostrea hongkongensis; p38 MAPK; Characterization; Expression profile; Innate immunity;
JNK and p38 mitogen-activated protein kinase pathways contribute to porcine epidemic diarrhea virus infection
Keywords: P38 MAPK; PEDV; p38 MAPK; JNK1/2; Signal transduction; Viral replication
Resveratrol ameliorates benzo(a)pyrene-induced testicular dysfunction and apoptosis: involvement of p38 MAPK/ATF2/iNOS signaling
Keywords: P38 MAPK; AhR; aryl hydrocarbon receptor; ATF2; activating transcription factor 2; BPDE; benzo(a)pyrene-7,8-diol-9,10-epoxide; CYP11A1; cytochrome P450 11A1; CYP1A1; cytochrome P450 1A1; iNOS; inducible nitric oxide synthase; MDA; malondialdehyde; PARP; poly-ADP ri
Vascular and angiogenic activities of CORM-401, an oxidant-sensitive CO-releasing molecule
Keywords: P38 MAPK; Carbon monoxide; Carbon monoxide-releasing molecules; Vascular activity; Angiogenesis; Heme oxygenase-1; p38 MAPK
Inflammatory intracellular pathways activated by electronegative LDL in monocytes
Keywords: P38 MAPK; AP-1; activator protein 1; CREB; cAMP response element-binding; ERK; extracellular signal-regulated kinase; FPLC; fast protein liquid chromatography; IL; interleukin; JNK; c-jun N-terminal kinase; LDL(+); electropositive LDL; LDL(â); electronegative LDL
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation
Keywords: P38 MAPK; ALI; acute lung injury; APCs; antigen-presenting cells; ARE; antioxidant responsive element; Bach1; Broad complex-Tramtrack-Bric-a-brac (BNB) and Cap'n'collar (CNC) homolog 1; BAL; bronchoalveolar lavage; BR; bilirubin-IXα; BV; biliverdin-IXα; BVR;
Melatonin prevents secondary intra-abdominal hypertension in rats possibly through inhibition of the p38 MAPK pathway
Keywords: P38 MAPK; Intra-abdominal hypertension; Melatonin; Tight junction; p38 MAPK; Rats;
Inhibition of p38 mitogen-activated protein kinases attenuates renal interstitial fibrosis in a murine unilateral ureteral occlusion model
Keywords: P38 MAPK; p38 MAPK; Kidney; Interstitial fibrosis; Unilateral ureteral occlusion;
Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury
Keywords: P38 MAPK; Hippocampal neurotoxicity; Cerebral ischemia; Adenosine A1 receptor; AMPAR trafficking; Serine/threonine protein phosphatase; Adenosine-induced persistent synaptic depression; CPA; N6-cyclopentyl adenosine; DPCPX; 8-cyclopentyl-1,3-dipropylxanthine; APSD;
High glucose and hyperglycemic sera from type 2 diabetic patients impair DC differentiation by inducing ROS and activating Wnt/β-catenin and p38 MAPK
Keywords: P38 MAPK; DCs; dendritic cells; DM2; type 2 diabetes; ROS; reactive oxygen species; MAPKs; mitogen-activated protein kinases; PAMPs; pathogen associated molecular patterns; DAMPs; damage associated molecular patterns; TCF/LEF; T-cell factor/lymphoid enhancer factor
Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway
Keywords: P38 MAPK; HSC; hepatic stellate cells; ER; endoplasmic reticulum; BFA; Brefeldin A; IRE1α; inositol-requiring enzyme 1 alpha; ATF6α; activating transcription factor 6α; PERK; PKR-like ER kinase; PBA; phenylbutyric acid; ERK; extracellular-regulated kinase; JNK;
Oxidative stress modulates the cytokine response of differentiated Th17 and Th1 cells
Keywords: P38 MAPK; PB; Plumbagin; IFN-γ; Interferon-Gamma; IL-17; Interleukin-17; ROS; Reactive Oxygen Species; O2.â; Super oxide; H2O2; Hydrogen peroxide; TF; Transcription factor; Th2; T helper 2; Th17; T helper 17; PMA/Ion; Phorbol 12-myristate 13-acetate/Ionomycin; N
Structure-based de novo design and synthesis of aminothiazole-based p38 MAP kinase inhibitors
Keywords: P38 MAPK; De novo design; Kinase; p38 MAPK; Inhibitor; Anti-inflammatory drugs
Inhibition of respiratory syncytial virus replication and virus-induced p38 kinase activity by berberine
Keywords: P38 MAPK; Respiratory syncytial virus; Berberine; Antiviral activity; p38 MAPK
Identification of nuclear factor kappaB (NF-κB) binding motifs in Biomphalaria glabrata
Keywords: P38 MAPK; Biomphalaria glabrata; NF-κB; Electrophoretic mobility shift assays; p38 MAPK; IκB; Innate immunity
Anticancer drug bortezomib increases interleukin-8 expression in human monocytes
Keywords: P38 MAPK; Bortezomib; Interleukin-8; Macrophages; Monocytes; NFκB; p38 MAPK;
Polymethoxylated flavones potentiate the cytolytic activity of NK leukemia cell line KHYG-1 via enhanced expression of granzyme B
Keywords: P38 MAPK; Granzyme B; KHYG-1; NK cell; Nobiletin; Polymethoxylated flavone; p38 MAPK;
Methylglyoxal and Advanced Glycation End-Products Promote Cytokines Expression in Peritoneal Mesothelial Cells Via MAPK Signaling
Keywords: P38 MAPK; Mesothelial cells; Methylglyoxal; Advanced glycation end products; p38 MAPK;
Metformin reduces the endotoxin-induced down-regulation of apolipoprotein E gene expression in macrophages
Keywords: P38 MAPK; Metformin; Apolipoprotein E; NF-κB; Macrophages; Multienhancer; LPS; AMPK; adenosine-monophosphate-activated protein kinase; apoE; apolipoprotein E; cAMP; cyclic adenosine monophosphate; CD36; cluster of differentiation 36; Cox2; cyclooxygenase 2; DMEM;
Palmitate promotes autophagy and apoptosis through ROS-dependent JNK and p38 MAPK
Keywords: P38 MAPK; Palmitate; Apoptosis; Autophagy; ROS; JNK; p38 MAPK;
The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders
Keywords: P38 MAPK; BMMCs; bone marrow-derived murine mast cell; ECM; extracellular matrix; eQTLs; expression quantitative trait loci; ERK; extracellular signal-regulated kinases; GATA1; globin transcription factor 1; GATA2; globin transcription factor 2; GI tract; Gastroint
SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment
Keywords: P38 MAPK; 8-Chloro-cyclic AMP; SHC1; AMP-activated protein kinase; p38 MAP kinase; Cancer therapy; 8-Cl-cAMP; 8-Chloro-cyclic AMP; PKA; cyclic AMP-dependent protein kinase; AMPK; AMP-activated protein kinase; p38 MAPK; p38 mitogen-activated protein kinase; SHC1; Sr
Dehydroepiandrosterone-enhanced dual specificity protein phosphatase (DDSP) prevents diet-induced and genetic obesity
Keywords: P38 MAPK; Dehydroepiandrosterone; DHEA-enhanced dual specificity protein phosphatase; Obesity; p38 MAPK; Leptin; DHEA; dehydroepiandrosterone; DDSP; DHEA-enhanced dual specificity protein phosphatase; MAPK; mitogen-activated protein kinase; WAT; white adipose tissu
The role of p38MAPK signal pathway in the neuroprotective mechanism of limb postconditioning against rat cerebral ischemia/reperfusion injury
Keywords: P38 MAPK; Limb ischemic postconditioning; Cerebral ischemia/reperfusion; Stroke; Apoptosis; p38 MAPK; ATF2;
The intrathecal administration of losartan, an AT1 receptor antagonist, produces an antinociceptive effect through the inhibiton of p38 MAPK phosphorylation in the mouse formalin test
Keywords: P38 MAPK; Losartan; Angiotensin II; p38 MAPK; Formalin test; Intrathecal administration; Mice;
Buforin IIb induces endoplasmic reticulum stress-mediated apoptosis in HeLa cells
Keywords: P38 MAPK; Buforin IIb; Anticancer peptide; Apotosis; ER stress; Mitochondrial membrane permeabilization; AMP; antimicrobial peptide; ER; endoplasmic reticulum; SAPK/JNK; stress-activated protein kinase/Jun-amino-terminal kinase; p38 MAPK; p38 mitogen-activated prot
Sigma 1 Receptor antagonist potentiates the anti-cancer effect of p53 by regulating ER stress, ROS production, Bax levels, and caspase-3 activation
Keywords: P38 MAPK; p53; Sigma 1 Receptor; ER stress; Apoptosis; p38 MAPK; ROS
MicroRNA-761 regulates mitochondrial biogenesis in mouse skeletal muscle in response to exercise
Keywords: P38 MAPK; MicroRNA-761; PGC-1α; Mitochondrial biogenesis; p38 MAPK
Inhibitory effects of PPARγ ligands on TGF-β1-induced CTGF expression in cat corneal fibroblasts
Keywords: P38 MAPK; Rosiglitazone; Troglitazone; 15d-PGJ2; JNK; p38 MAPK; ERK; AKT; CTGF; connective tissue growth factor; CCN; cyr61, ctgf, neuroblastoma over-expressed gene; Nov; neuroblastoma over-expressed gene; ECM; extracellular matrix; PRK; photorefractive keratectomy