دانلود مقالات ISI درباره p70S6 کیناز + ترجمه فارسی

Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity

Keywords: p70S6 کیناز; Environmental enrichment; Social enrichment; Morris water maze; mGluR; LTP; p70S6 kinase; Homer1c;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway

Keywords: p70S6 کیناز; Agmatine; Akt; HT22; Ketamine; Neuroprotection; p70S6 kinase; PSD95; 4E-BPs; 4E binding proteins; ANOVA; analysis of variance; DMEM; Dulbecco's Modified Eagle Medium; ECT; electroconvulsive therapy; CUS; chronic unpredictable stress; FST; forced swim test

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Flavan 3-ol delays the progression of disuse atrophy induced by hindlimb suspension in mice

Keywords: p70S6 کیناز; EDL; Extensor digitorum longus; FL; Flavan 3-ol; GC; Gastrocnemius; MuRF1; Muscle ring finger-1; p70S6K; p70S6 kinase; PGC-1α; Proliferator-activated receptor gamma coactivator-1 alpha; PI3K; Phosphoinositide 3-kinase; SOL; Soleus; TA; Tibialis anterior;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

p21-activated kinase 4 regulates HIF-1α translation in cancer cells

Keywords: p70S6 کیناز; Pak4; HIF-1α; Hypoxia; Akt; mTOR; 4E-BP1; Pak; p21-activated kinase; HIF; hypoxia-inducible factor; PHD; prolyl hydroxylase domain-containing protein; FBS; fetal bovine serum; HRE; hypoxia response element; PGK-1; phosphoglycerate kinase-1; DFO; desferri

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Sulforaphane inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation

Keywords: p70S6 کیناز; Sulforaphane (PubChem CID: 5350); Dimethyl Sulfoxide (PubChem CID: 679); ARE; antioxidant response element; CREB; cAMP-response element-binding protein; DAB; diaminobenzidine; DMSO; dimethyl sulfoxide; 4E-BP1; eukaryotic translation initiation factor 4E-b

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells

Keywords: p70S6 کیناز; AhR; aryl hydrocarbon receptor; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; CYP; cytochrome P-450; DEP; diesel exhaust particle; DEPe; diesel exhaust particle extract; DMSO; dimethyl sulfoxide; EGR1; early growth response 1; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K

Keywords: p70S6 کیناز; Saquinavir; Saquinavir-NO; Acute lymphoid leukemia; Acute myeloid leukemia; p70S6 kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Environmental enrichment improves learning and memory and long-term potentiation in young adult rats through a mechanism requiring mGluR5 signaling and sustained activation of p70s6k

Keywords: p70S6 کیناز; Young rats; Environmental enrichment; Metabotropic glutamate receptor; Morris water maze; Object recognition; p70s6 kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

p70S6 kinase is a critical node that integrates HER-family and PI3 kinase signaling networks

Keywords: p70S6 کیناز; p70S6K; p70S6 kinase; PI3K; phosphoinositide-3-kinase; RPPA; Reverse Phase Protein Array; mTOR; mammalian target of rapamycin; MAPK; mitogen activated protein kinase; EGFR; epidermal growth factor receptor; NSCLC; non-small cell lung cancer; RTK; receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Iron chelators induce autophagic cell death in multiple myeloma cells

Keywords: p70S6 کیناز; Iron chelation; Deferasirox; Deferoxamine; Multiple myeloma; Autophagy; mTOR; p70S6 kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Jurkat cell proliferation is suppressed by Chlamydia (Chlamydophila) pneumoniae infection accompanied with attenuation of phosphorylation at Thr389 of host cellular p70S6K

Keywords: p70S6 کیناز; PBMC; peripheral blood mononuclear cell; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; LPS; lipopolysaccharide; HBSS; Hank's balanced salt solution; PI3K; mammalian target of rapamycin; mTOR; phosphoinositide 3-kinase; mTORC1; multi-component m

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

α-Terpineol induces fatty liver in mice mediated by the AMP-activated kinase and sterol response element binding protein pathway

Keywords: p70S6 کیناز; α-Terpineol; SREBP; AMPK; mTOR; p70S6 kinase; Fatty liver;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The role of RhoC in ovarian epithelial carcinoma: A marker for carcinogenesis, progression, prognosis, and target therapy

Keywords: p70S6 کیناز; Ovarian carcinoma; RhoC; Aggressive phenotypes; Pathobiological behavior; Prognosis; P70S6 kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

β-Adrenergic system, a backstage manipulator regulating tumour progression and drug target in cancer therapy

Keywords: p70S6 کیناز; FAK; focal adhesion kinase; PKA; protein kinase A; BAD; BCL2-associated death protein; VEGF; vascular endothelial growth factor; PlGF; placenta-derived growth factor; PDGF; platelet-derived growth factor; TGF-β; transforming growth factor β; HIF-1α; hy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Ferulic acid attenuates focal cerebral ischemia-induced decreases in p70S6 kinase and S6 phosphorylation

Keywords: p70S6 کیناز; Ferulic acid; Neuroprotection; mTOR; p70S6 kinase; S6;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Phospholipase D-mTOR signaling is compromised in a rat model of depression

Keywords: p70S6 کیناز; Depression; Phospholipase D; Choline; Phosphatidic acid; mTOR; p70S6 kinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-cancer properties of glucosamine-hydrochloride in YD-8 human oral cancer cells: Induction of the caspase-dependent apoptosis and down-regulation of HIF-1α

Keywords: p70S6 کیناز; Apaf-1; apoptotic protease activating factor-1; Bcl-2; B cell lymphoma-2; Bcl-xL; B cell lymphoma-extra large; DCFH-DA; 2′,7′-dichlorofluorescein-diacetate; ECL; enzyme-linked chemiluminescence; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dual blockade of phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer

Keywords: p70S6 کیناز; Paclitaxel; PI3K; MAPK; p70S6 Kinase; Colorectal cancerPI3K, phosphatidylinositol 3′-kinase; MAPK, mitogen-activated protein kinase; mTOR, mammalian target of rapamycin; PTEN, phosphatase and tensin homologue; 5-FU, 5-fluoropyrimidine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Changes in growth-related kinases in head, neck and limb muscles with age

Keywords: p70S6 کیناز; Aging; Muscle; Tongue; p70s6 kinase; MAP kinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Dietary fish oil inhibits the early stage of recovery of atrophied soleus muscle in rats via Akt–p70s6k signaling and PGF2α

Keywords: p70S6 کیناز; Dietary fish oil; Muscle recovery; Akt; p70s6 kinase; Prostaglandin F2α; Cyclooxygenase-2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Roles of Ets-1 and p70S6 kinase in chondrogenic and gliogenic specification of mouse mesencephalic neural crest cells

Keywords: p70S6 کیناز; Mesencephalic neural crest cells; Chondrogenesis; Gliogenesis; Fibroblast growth factors; Erk pathway; Akt pathway; Ets-1; p70S6 kinase; Notch signaling; Mouse

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: Potent and selective p70S6 kinase inhibitors

Keywords: p70S6 کیناز; p70S6K; p70S6 Kinase; 1,2,5-Oxadiazole; 3-Aminofurazan

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

TIS21/BTG2/PC3 and cyclin D1 are key determinants of nuclear diacylglycerol kinase-ζ-dependent cell cycle arrest

Keywords: p70S6 کیناز; cdk; cyclin dependent kinase; DG; diacylglycerol; DGK; diacylglycerol kinase; ECL; enhanced chemiluminescence; GSK; glycogen synthase kinase; mTOR; mammalian Target Of Rapamycin; NLS; nuclear localization signal; p70S6K; p70S6 kinase; PA; phosphatidic aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension

Keywords: p70S6 کیناز; Angiogenesis; Vascular endothelial growth factor; Portal pressure; Myosin light chain; P70S6 kinase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Estradiol attenuates the focal cerebral ischemic injury through mTOR/p70S6 kinase signaling pathway

Keywords: p70S6 کیناز; Akt; Estradiol; mTOR; Neuroprotection; p70S6 kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway

Keywords: p70S6 کیناز; Melatonin; mTOR; Neuroprotection; p70S6 kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Aβ overproduction

Keywords: p70S6 کیناز; Aβ; Tau; p70S6 kinase; Alzheimer’s disease

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

TOR signaling is required for amino acid stimulation of early trypsin protein synthesis in the midgut of Aedes aegypti mosquitoes

Keywords: p70S6 کیناز; Rapamycin; RNAi; 4E-BP; p70S6 Kinase; Translational control; Blood meal metabolism

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

Keywords: p70S6 کیناز; HCC; Hepatocellular carcinoma; VEGF; vascular endothelial growth factor; BEV; Bevacizumab; mTOR; mammalian target-of-rapamycin; p70S6K; p70S6 kinase; RPS6; ribosomal S6 protein; 4EBP1; eukaryotic initiation factor 4E-binding protein 1; RAPA; rapamycin; IP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft

Keywords: p70S6 کیناز; HCC; hepatocellular carcinoma; RTKIs; tyrosine kinase inhibitors; MAPK; mitogen activated protein kinase; VEGF; vascular endothelial growth factor; mTOR; mammalian target of rapamycin; p70S6K; p70S6 kinase; 4EBP1; eukaryotic initiation factor 4E-binding p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Phosphorylation events implicating p38 and PI3K mediate tungstate-effects in MIN6 beta cells

Keywords: p70S6 کیناز; PDX-1; pancreatic duodenal homeobox-1; p38; p38 MAP kinase; PI3K; phosphatidylinositol 3-kinase; p70S6K; p70S6 kinase; nSTZ; neonatally streptozotocin; GIIS; glucose-induced insulin secretion; Tungstate; Beta cell; Insulin secretion; Pancreatic duodenal h

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Monitoring Biological Action of Rapamycin in Renal Transplantation

Keywords: p70S6 کیناز; Kidney transplantation; rapamycin; tacrolimus; P70S6 kinase; peripheral-blood mononuclear cells; in vivo assay;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Rapamycin inhibits human renal epithelial cell proliferation: Effect on cyclin D3 mRNA expression and stability

Keywords: p70S6 کیناز; rapamycin; p70S6 kinase; cyclin D; delayed graft function; renal transplantation

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه