Keywords: پانین; Immune Response; Kras; PDAC; Tumorigenesis; ADM; Acinar-ductal metaplasia; AKT; protein kinase B; ERK; extracellular signal-regulated kinase; ESC; embryonic stem cell; GFP; green fluorescent protein; IL; interleukin; IL17R; interleukin 17 receptor; JNK;
مقالات ISI پانین (ترجمه نشده)
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Keywords: پانین; Early Detection; Familial Pancreatic Cancer; IPMN; PanIN-3; CAPS; Cancer of the Pancreas Screening; CT; computed tomography; EUS; endoscopic ultrasonography; FPC; familial pancreatic cancer; HGD; high-grade dysplasia; HR; hazard ratio; HRI; high-risk indi
Keywords: پانین; Pancreatic Cancer; Oncocytic; PanIN; Gastric; Brg1; Brahma Protein-Like 1; IPMN; intraductal papillary mucinous neoplasia; Kras; Kirsten Rat Sarcoma Viral Oncogene Homolog; KrasG12D; LSL-KrasG12D allele; KrasG12D;PtenÎDuct/+; Sox9CreERT2;KrasG12D;Ptenflo
Keywords: پانین; Pancreatic stellate cells; Stroma; Bio-marker; PanIN; Precursor; pIgR; PDAC;
Keywords: پانین; Pancreatic cancer; AFL; IPMN; PanIN;
Keywords: پانین; 5-hydroxytryptamine; Tryptophan Hydroxylase; 5-HT2B; Pancreatic Intraepithelial Neoplasia; 5-HT; serotonin (5-hydroxytryptamine); CT; computed tomography; ECAR; extracellular acid ratio; HTRs; 5-HT receptors; KPC; KrasG12D/+/Trp53R172H/+/Pdx1-Cre; IHC; im
Keywords: پانین; Pancreatic cancer; Disease animal models; Comparative pathology; Molecular imaging; Proliferation; PDAC; pancreatic ductal adenocarcinoma; KC; LSL-KrasG12D/+, Pdx-1-Cre; KPC; LSL-KrasG12D/+, LSL-Trp53R172H/+, Pdx-1-Cre; PanIN; pancreatic intraepithelial n
Keywords: پانین; adenocarcinoma; chronic pancreatitis; grossing; intraoperative consultation; IPMN; neoadjuvant chemotherapy; pancreas; PanIN
Keywords: پانین; Pancreas adenocarcinoma; IPMN; PanIN; CT; MRI;
Keywords: پانین; Pancreatic cancer; Hereditary; Screening; Peutz-Jeghers; BRCA; Lynch syndrome; IPMN; PanIN;
Keywords: پانین; Pancreatic Cancer; Surgery; Adjuvant Therapy; Resectable Transgenic Mice; ADM; acinar-to-ductal metaplasia; CONKO-001; Charité Onkologie-001; EGFP; enhanced green fluorescent protein; EP; electroporation technique; Erk; extracellular signal-regulated k
Keywords: پانین; Chemotherapy; Imaging; Pancreatic cancer; Pathology; Radiotherapy; Targeted therapy; 18FDG-PET; 18F-fluorodeoxyglucose-positron emission tomography; 5FU; 5-fluorouracil; α-SMA; α-smooth muscular actin; AA; amino acid; APA; adapted physical activity; ATP
Keywords: پانین; ARF; alternative reading frame; αSMA; alpha smooth muscle actin; CDK; cyclin-dependent kinase; DDR; DNA damage response; ECM; extracellular matrix; EMT; epithelial mesenchymal transition; FGF; fibroblast growth factor; HDAC; histone deacetylase; HIC1; hy
Keywords: پانین; Pancreatic Cancer; Pathogenesis; Mouse Model; Signal Transduction; ADM; acinar-to-ductal metaplasia; COX; cyclooxygenase; DAPI; 4â²,6-diamidino-2-phenylindole; DCLK1; doublecortin-like kinase 1; EGFR; epidermal growth factor receptor; IF; immunofluoresce
Keywords: پانین; PDAC; Pancreatic ductal adenocarcinoma; CT; computerized tomography; EUS; endoscopic ultrasound; ERCP; endoscopic retrograde cholangiopancreatography; CA; Carbohydrate antigen/cancer antigen; CEA; carcinoembryonic antigen; EGTM; European Group on Tumor Ma
Expression of neuropeptide Y and its receptors Y1 and Y2 in pancreatic intraepithelial neoplasia and invasive pancreatic cancer in a transgenic mouse model and human samples of pancreatic cancer
Keywords: پانین; PanIN; Snail; Pancreatic injury; ADM; PDAC; NPY; Y1; Y2; IPMN;
Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer
Keywords: پانین; 3D Organoids; Pancreas; Adenocarcinoma; Personalized Medicine; 3D; 3-dimensional; GEMMs; genetically engineered mouse models; PanIN; pancreatic intraepithelial neoplasia; PDAC; pancreatic ductal adenocarcinoma; PDX; patient-derived tumor xenografts;
Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth
Keywords: پانین; PDA; pancreatic ductal adenocarcinomas; PanIN; pancreatic epithelial lesions; GFR; growth factor reduced; DOX; doxycycline; 3D; three-dimensional; Usp9x-OV; Usp9x overexpression; DUB; deubiquitinase;
Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer
Keywords: پانین; CCK Receptor; Gene Therapy; Gastrin; Nanotechnology; Orthotopic; CCK; cholecystokinin; Ex/Em; maximal excitation and emission wavelengths; Ga-10; gastrin 10 peptide; mRNA; messenger RNA; MW; molecular weight; N/P; ratio of “amines” of poly (L-lysine)
ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice
Keywords: پانین; Oncogene; Pancreatic Cancer; Transcriptional Regulator; Tumorigenesis; 2D; 2-dimensional; 3D; 3-dimensional; ATP; adenosine triphosphate; IPMN; intraductal papillary mucinous neoplasm; MCN; mucinous cystic neoplasm; PI3K; phosphatidylinositol 3-kinase; Pa
Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy
Keywords: پانین; PTEN; Kras; Cholangiocarcinoma; Pancreatic cancer; ICC; Intrahepatic cholangiocarcinoma; HCC; hepatocellular carcinoma; ECC; extrahepatic bile duct carcinoma; PanIN; premalignant pancreatic intraepithelial neoplasms; PDAC; pancreatic ductal adenocarcinoma
Expression Undercurrents of Sonic Hedgehog in Colorectal and Pancreatic Cancers
Keywords: پانین; Colorectal cancer; CRC; Pancreatic cancer; PC; Sonic hedgehog; SHH; Indian hedgehog; IHH; Desert hedgehog; DHH; Bone morphogenetic protein; BMP; Transforming growth factor; TGFβ; Pancreatic intra epithelial lesions; PanIN; Pancreatic ductal adenocarcinom
IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
Keywords: پانین; BALF; bronchoalveolar lavage fluid; CAC; colitis-associated cancer; CAF; cancer associated fibroblast; ccRCC; clear cell renal cell carcinoma; CLC; cardiotrophin-like cytokine; CML; chronic myeloid leukemia; CNTF; ciliary neurotrophic factor; COPD; chroni
Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo180
Keywords: پانین; Pancreatic cancer; Pancreatic stellate cells; Leading cells; Extracellular matrix remodeling; Endo180; ECM; extracellular matrix; PSCs; pancreatic stellate cells; PCCs; pancreatic cancer cells; MLC2; myosin light chain 2; αSMA; α-smooth muscle actin; MM
Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice
Keywords: پانین; Gene Regulation; Oncogene; Pancreas; Signal Transduction; ADM; acinar-to-ductal metaplasia; CCND1; cyclin D1; ChIP; chromatin immunoprecipitation; DMSO; dimethyl sulfoxide; IF; immunofluorescence; IHC; immunohistochemical; KLF; Krüppel-like factor; KRAS;
Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy
Keywords: پانین; CAFs; cancer-associated fibroblasts; CIS; carcinoma in situ; CSCs; cancer stem cells; CXCL12; CXC ligand 12; CXCR4; CXC chemokine receptor 4; EMT; epithelial mesenchymal transition; HMGB1; high mobility group box 1; MDSCs; myeloid-derived suppressor cells
Increased Bcl-xL Expression in Pancreatic Neoplasia Promotes Carcinogenesis by Inhibiting Senescence and Apoptosis
Keywords: پانین; Kras; PanINs; Bcl-2 Family Protein; IHC; immunohistochemistry; KO; knockout; P-KrasG12D; Pdx1-Cre LSL-KrasG12D; PanIN; pancreatic intraepithelial neoplasia; PDAC; pancreatic ductal adenocarcinoma; SA-β-gal; senescence-associated β-galactosidase; siRNA
Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis
Keywords: پانین; Pancreas; Cancer; TGFβ; Acinar-to-Ductal Metaplasia; KRASG12D; ADM; acinar-to-ductal metaplasia; AFI; acinar fatty infiltration; EMT; epithelial-to-mesenchymal transition; PanIN; pancreatic intraepithelial neoplasia; PBS; phosphate-buffered saline; PDA;
Using an endoscopic distal cap to collect pancreatic fluid from the ampulla (with video)
Keywords: پانین; ddPCR; droplet-digital PCR; IPMN; intraductal papillary mucinous neoplasm; IQR; interquartile range; PanIN; pancreatic intraepithelial neoplasia;
Current modalities in cancer immunotherapy: Immunomodulatory antibodies, CARs and vaccines
Keywords: پانین; AAH; atypical adenomatous hyperplasia; AK; actinic keratosis; AML; acute myelogenous leukemia; AMM; asymptomatic multiple myeloma; APC; antigen presenting cell; B-ALL; B cell acute lymphocytic leukemia; B-CLL; B cell chronic lymphocytic leukemia; BD; Bowe
Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia
Keywords: پانین; Incipient IPMN; IPMN; PanIN; Meckel diverticulum; KRAS
Facteurs prédisposants de l'adénocarcinome pancréatique : quel est le rôle de l'imagerie ?
Keywords: پانین; Adénocarcinome pancréatique; TIPMP; PanIN; TDM; IRM;
Molecular pathogenesis of pancreatic ductal adenocarcinoma
Keywords: پانین; CDKN2A; driver genes; KRAS; pancreatic ductal adenocarcinoma; PanIN; SMAD4; TP53
Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions
Keywords: پانین; pancreatic cancer; PanIN; Kras; oxidative stress; mitochondria; growth factor signaling
Original ResearchFull Report: Basic and Translational-PancreasYAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling
Keywords: پانین; PanINs; Pancreatic Cancer Progression; Mouse Model; Inflammation; ADM; acinar-to-ductal metaplasia; CMV; cytomegalovirus; ES; embryonic stem cell; HBSS; Hank's balanced salt solution; IL; interleukin; PanIN; pancreatic intraepithelial neoplasia; PBS; ph
Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver
Keywords: پانین; Tissue Inhibitor of Metalloproteinases; Tumor Progression; Signal Transduction; Microenvironment; CP; chronic pancreatitis; HSC; hepatic stellate cell; PanIN; pancreatic intra-epithelial neoplasia; PDAC; pancreatic ductal adenocarcinoma; PDGF-B; platelet-
ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer
Keywords: پانین; EMT; Pancreas; Cancer; Gene Regulation; 3D; 3-dimensional; ECAD; E-cadherin; ECM; extracellular matrix; EMT; epithelialâmesenchymal transition; HA; hyaluronic acid; Has2; hyaluronan synthase 2; KC; Pdx1-Cre;LSL-KrasG12D; KPfC; Pdx1-Cre;LSL-KrasG12D;Trp5
SOX9: a useful marker for pancreatic ductal lineage of pancreatic neoplasms
Keywords: پانین; SOX9; Centroacinar cells; Pancreatic ductal adenocarcinoma; PanIN; IPMN; MCN; SCA; ACC; PET; SPN;
DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer
Keywords: پانین; PanIN; Kras; Notch; Acetylated TubulinAcTub, acetylated α-tubulin; ADM, acinar-to-ductal metaplasia; Dclk1, doublecortin and Ca2+/calmodulin-dependent kinase-like 1; FACS, fluorescence-activated cell sorting; GFP, green fluorescent protein; mPanIN, murine
PI3K Regulation of RAC1 Is Required for KRAS-Induced Pancreatic Tumorigenesis in Mice
Keywords: پانین; Pancreatic Cancer; Signal Transduction; Cytoskeleton; Oncogene; ADM; acinar-to-ductal metaplasia; DAPI; 4â²,6-diamidino-2-phenylindole; EGFR; epidermal growth factor receptor; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GEF; guanine nucleotide excha
MAPK Signaling Is Required for Dedifferentiation of Acinar Cells and Development of Pancreatic Intraepithelial Neoplasia in Mice
Keywords: پانین; Pancreatic Cancer; Signal Transduction; Mouse Models; Acinar Differentiation; ADM; acinar-ductal metaplasia; ERK1/2; extracellular signal-regulated kinase1/2; iKras*; inducible-KrasG12D (p48Cre,TetO-KrasG12D,Rosa26rtTa-IRES-EGFP); KC; p48Cre,LSL-KrasG12D;
Original ResearchFull Report: Basic and Translational-PancreasFascin Is Regulated by Slug, Promotes Progression of Pancreatic Cancer in Mice, and Is Associated With Patient Outcomes
Keywords: پانین; Pancreas; Tumor Progression; Actin Cytoskeleton; EMT; EMT; epithelial to mesenchymal transition; FKPC; fascin-deficient KRasG12D p53R172H Pdx1-Cre; KPC; KRasG12D p53R172H Pdx1-Cre; MC; mesothelial cell; PanIN; pancreatic intraepithelial neoplasia; PDAC; p
Down-regulation of MicroRNA-494 via Loss of SMAD4 Increases FOXM1 and β-Catenin Signaling in Pancreatic Ductal Adenocarcinoma Cells
Keywords: پانین; Pancreatic Cancer; Gene Regulation; Signal Transduction; Tumor Progression; FOXM1; Forkhead box M1; LMD; laser-assisted microdissection; miRNA; microRNA; mRNA; messenger RNA; PanIN; pancreatic intraepithelial neoplasia; PCR; polymerase chain reaction; PDA
Trisomy of the Dscr1 gene suppresses early progression of pancreatic intraepithelial neoplasia driven by oncogenic Kras
Keywords: پانین; Dscr1; Down syndrome critical region-1; NFAT; nuclear factor of activated T-cells; PanIN; pancreatic intraepithelial neoplasia; PDA; pancreatic ductal adenocarcinoma; Dyrk1a; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; CK-19; cytoke
The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models
Keywords: پانین; PanIN; pancreatic intraepithelial neoplasia; PDAC; pancreatic ductal adenocarcinoma; PPP2R2A; protein phosphatase 2, regulatory subunit B, alpha; Kras; Tp53; PPP2R2A; PanIN; Pancreatic cancer;
Original ResearchFull Report: Basic and Translational-PancreasGenetic Alterations Associated With Progression From Pancreatic Intraepithelial Neoplasia to Invasive Pancreatic Tumor
Keywords: پانین; Pancreas; Tumorigenesis; LCM; Whole-Genome Amplification; AAF; alternate allele frequency; ATM; ataxia telangiectasia mutated; LCM; laser capture microdissection; P; pancreatic intraepithelial neoplasia alone; PanIN; pancreatic intraepithelial neoplasia;
Stem cells & pancreatic cancer
Keywords: پانین; Pancreatic adenocarcinoma; Cancer stem cells; CD133; CD44; Metastasis; Immunotherapy; ALDH; aldehyde dehydrogenase; CSC; cancer stem cell; EMT; epithelial mesenchymal transition; EpCAM; epithelial cell adhesion molecule; PanIN; pancreatic intraepithelial
Pancreatic ductal adenocarcinomas with multiple large cystic structures: A clinicopathologic and immunohistochemical study of seven cases
Keywords: پانین; Pancreas; Cyst; Multiple large cysts; Ductal adenocarcinoma; PanIN
Technologies for Imaging the Normal and Diseased Pancreas
Keywords: پانین; Pancreatitis, Chronic; Cholangiopancreatography, Endoscopic Retrograde; Ultrasonography; Pancreatic Neoplasms; Early Detection; Cath E; Cathepsin E; C-CPE; Clostridium perfringens enterotoxin; CLE; confocal laser endomicroscopy; ERCP; endoscopic retrograd
Inflammation, Autophagy, and Obesity: Common Features in the Pathogenesis of Pancreatitis and Pancreatic Cancer
Keywords: پانین; Pancreatic Acinar Cell; Cytokines; Neutrophil; Pancreatic Ductal Adenocarcinoma; K-Ras; AMP; adenosine monophosphate; AP; acute pancreatitis; ATG; autophagy related; Cat; cathepsin; CP; chronic pancreatitis; DAMP; damage/danger-associated molecular patter