دانلود مقالات ISI درباره پچ گیر + ترجمه فارسی

A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method

Keywords: پچ گیر; Nefazodone; hERG; Patch clamp; Cardiotoxicity; HEK-293 cells;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Block of GABAA receptor ion channel by penicillin: Electrophysiological and modeling insights toward the mechanism

Keywords: پچ گیر; GABAA receptor; Penicillin; Isolated neurons; Patch clamp; Molecular modeling; Monte-Carlo energy minimization

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

PACAP induces plasticity at autonomic synapses by nAChR-dependent NOS1 activation and AKAP-mediated PKA targeting

Keywords: پچ گیر; Neuropeptide; pituitary adenylate cyclase activating polypeptide; Neuronal nitric oxide synthase; Nicotinic acetylcholine receptor; Alpha-7; Synapse; Synaptic transmission; Synaptic plasticity; Patch clamp; Excitatory postsynaptic current; Stress disorder

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Analysis of G-protein-activated inward rectifying K+ (GIRK) channel currents upon GABAB receptor activation in rat supraoptic neurons

Keywords: پچ گیر; Supraoptic nucleus; GIRK channels; GABAB receptors; Gi/o; Patch clamp; RT-PCR;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

5HT1B receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula

Keywords: پچ گیر; Epithalamus; Serotonin; EPSCs; Patch clamp; Synaptic plasticity4AP, 4-aminopyridine; 5-CT, 5-carboxyamidotryptamine; 5HT, 5-hydroxytryptamine; 8-OH-DPAT, 8-hydroxy-2-(di-n-propylamino)tetralin; AC, adenylyl cyclase; aCSF, artificial cerebrospinal fluid; C

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

CB1 cannabinoid receptor agonist prevents NGF-induced sensitization of TRPV1 in sensory neurons

Keywords: پچ گیر; Cannabinoids; Analgesia; Nociceptor; NGF; TRPV1; Patch clamp;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Donepezil in low micromolar concentrations modulates voltage-gated potassium currents in pyramidal neurons of rat hippocampus

Keywords: پچ گیر; Donepezil; Hippocampus; K+-current; Pyramidal neurons; Patch clamp;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Reduced spike frequency adaptation in Purkinje cells of the vestibulocerebellum

Keywords: پچ گیر; ACSF; artificial cerebrospinal fluid; AP; action potential; CV; coefficient of variation; DCN; deep cerebellar nucleus; fAHP; fast afterhyperpolarization; GFN; gap firing neuron; HFF; high-frequency firing; HSN; head-shaking nystagmus; ISI; interspike int

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibitory effects of levetiracetam on the high-voltage-activated L-type Ca2+ channels in hippocampal CA3 neurons of spontaneously epileptic rat (SER)

Keywords: پچ گیر; Levetiracetam (LEV); Ca2+ current; Spontaneously epileptic rat (SER); Hippocampal CA3 neuron; Patch clamp;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Predicted drug-induced bradycardia related cardio toxicity using a zebrafish in vivo model is highly correlated with results from in vitro tests

Keywords: پچ گیر; Bradycardia; Cardio toxicity; Zebrafish; Patch clamp; Fluorescence polarity; In vivo/in vitro correlation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A history of the role of the hERG channel in cardiac risk assessment

Keywords: پچ گیر; hERG; human ether-a-go-go-related gene; TdP; torsades de pointes; TQT; thorough QT trial; Agonists; Blockers; hERG; Methods; Modeling; Patch clamp; Trafficking;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Beta amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease mice

Keywords: پچ گیر; Alzheimer's disease; Calcium signaling; Beta-amyloid protein; Hippocampus; Transgenic mice; Patch clamp; 2-photon imaging;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Specific functioning of Cav3.2 T-type calcium and TRPV1 channels under different types of STZ-diabetic neuropathy

Keywords: پچ گیر; [Ca2 +]i; cytosolic Ca2 + concentration; DRG; dorsal root ganglia; HMP; holding membrane potential; IB4; isolectin B4; LVA/HVA; low/high voltage activated; NTCN; nonpeptidergic thermal C-type nociceptive (neurons); PCD; peak current density; PDN; periph

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

A critical evaluation of whole cell patch clamp studies on electroporation using the voltage sensitive dye ANNINE-6

Keywords: پچ گیر; BSA, bovine serum albumin; BTP, Bis-Tris propane; BY-2, bright yellow-2; EGTA, ethylene glycol tetraacetic acid; EK +, Nernst potential for K+; SD, standard deviation; VBI-0, Virginia bright Italian-0Electroporation; Patch clamp; Field-induced membrane po

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Atrial reverse remodeling: Restitution of early tachycardia-induced alterations of atrial ion currents after termination of rapid atrial pacing in rabbits

Keywords: پچ گیر; Atrial remodeling; Atrial reverse remodeling; Rapid atrial pacing; Atrial fibrillation; Patch clamp

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Cholinergic modulation of primary afferent glutamatergic transmission in rat medullary dorsal horn neurons

Keywords: پچ گیر; Presynaptic mACh receptors; EPSCs; Medullary dorsal horn; Patch clamp; PainACh, acetylcholine; ACSF, artificial cerebrospinal fluid; AChE, acetylcholinesterase; AF-DX116, 11-[[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Pregnenolone sulfate modulates glycinergic transmission in rat medullary dorsal horn neurons

Keywords: پچ گیر; Pregnenolone sulfate; Presynaptic facilitation; Glycine receptors; Pain; Patch clamp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of pulse magnetic field stimulation on calcium channel current

Keywords: پچ گیر; Pulse magnetic field; Ion channel; Patch clamp

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

A new technique for multiple re-use of planar patch clamp chips

Keywords: پچ گیر; Patch clamp; Planar chips; Electrophysiology;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

A sodium channel myotonia due to a novel SCN4A mutation accompanied by acquired autoimmune myasthenia gravis

Keywords: پچ گیر; Skeletal muscle; Myasthenia gravis; Electrophysiology; Patch clamp; Na channel; NaV1.4;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

A422T mutation in HERG potassium channel retained in ER is rescurable by pharmacologic or molecular chaperones

Keywords: پچ گیر; Potassium channel; HERG; Long QT syndrome; Patch clamp; Protein trafficking

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitory effects of a bisbenzylisoquinline alkaloid dauricine on HERG potassium channels

Keywords: پچ گیر; Dauricine; HEK293 cells; HERG; Patch clamp; Potassium channel; APD prolongation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research Reportl-aspartate effects on single neurons and interactions with glutamate in striatal slice preparation from chicken brain

Keywords: پچ گیر; Avian brain; Striatum; Aspartate; Glutamate; Excitatory amino acid; Patch clamp;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

The effect of ligustrazine on L-type calcium current, calcium transient and contractility in rabbit ventricular myocytes

Keywords: پچ گیر; Ligustrazine; Patch clamp; L-type calcium channel; Myocyte shortening; Calcium transient; Calcium overload;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Adenosine A2a receptor antagonists attenuate striatal adaptations following dopamine depletion

Keywords: پچ گیر; Adenosine; Dopamine; A2a; D2; Cholinergic interneuron; Medium spiny neuron; Striatopallidal; Patch clamp; Two photon laser scanning microscopy; Spine; Parkinson's disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties

Keywords: پچ گیر; ACSF; artificial cerebral spinal fluid; AHP; afterhyperpolarization; AP; action potential; AP5; D-2-amino-5-phosphonovalerate; 4-AP; 4-aminopyridine; AVPNs; airway vagal preganglionic neurons; CbTx; charybdotoxin; cNA; compact portion of the nucleus ambig

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Ca2+ channel currents in dorsal root ganglion neurons of P/Q-type voltage-gated Ca2+ channel mutant mouse, rolling mouse Nagoya

Keywords: پچ گیر; ω-ATX, ω-agatoxin IVA; 4-AP, 4-aminopyridine; ω-CTX, ω-conotoxin GVIA; DRG, dorsal root ganglion; NMDG, N-methyl-d-glucamine; TEA, tetraethylammonium; TTX, tetrodotoxin; VGCC, voltage-gated Ca2+ channelω-Agatoxin IVA; ω-Conotoxin GVIA; Patch clamp; Ba2+ c

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Muscarinic M4 receptors regulate GABAergic transmission in rat tuberomammillary nucleus neurons

Keywords: پچ گیر; Presynaptic M4 receptors; mIPSCs; Tuberomammillary nucleus; Patch clamp; Sleep-wakefulness; TMN; tuberomammillary nucleus; ACh; acetylcholine; mACh; muscarinic acetylcholine; mIPSCs; miniature inhibitory postsynaptic currents; eIPSCs; evoked inhibitory po

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Constant electric field simulations of the membrane potential illustrated with simple systems

Keywords: پچ گیر; Electrostatics; Electrodes; Free energy; Patch clamp;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Escape capture bigeminy: Phenotypic marker of cardiac sodium channel voltage sensor mutation R222Q

Keywords: پچ گیر; Sodium channel; SCN5A; Nav1.5; Mutation; Patch clamp; Voltage clamp; Bigeminy; AF; atrial fibrillation; EP; electrophysiological; WT; wild type;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation

Keywords: پچ گیر; Cardiac arrhythmias; Ion channels; Long QT syndrome; Patch clamp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

High resolution electrophysiological techniques for the study of calcium-activated exocytosis

Keywords: پچ گیر; Exocytosis; Transmitter release; Fusion pore; Patch clamp; Capacitance measurement

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Negative-shift activation, current reduction and resurgent currents induced by β-toxins from Centruroides scorpions in sodium channels

Keywords: پچ گیر; β-Scorpion toxin; Centruroides; Patch clamp; Three-dimensional models; Voltage-gated sodium channel; HPLC; high performance liquid chromatography; HEK; human embryonic kidney; Nav; Na+-channel; TTX; tetrodotoxin; VGSCs; voltage-gated sodium channels;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): The first member of a new κ-KTX subfamily

Keywords: پچ گیر; Scorpion toxin; Voltage-gated potassium channel; Electrophysiology; Patch clamp; cDNA; Heterometrus laoticus

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Promethazine inhibits NMDA-induced currents – New pharmacological aspects of an old drug

Keywords: پچ گیر; Promethazine; Phenothiazine; NMDA receptor; Patch clamp; Sedation; Analgesia; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Electrical synapses between AII amacrine cells in the retina: Function and modulation

Keywords: پچ گیر; Adaptation; Amacrine; Connexin; Electrical coupling; Gap junction; Neuromodulation; Patch clamp; Retina

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Studying mitochondrial Ca2+ uptake - A revisit

Keywords: پچ گیر; Mitochondrial Ca2+ measurements; Mitochondrial Ca2+ uptake; Mitochondrial Ca2+ uniporter; Mitoplasts; Patch clamp; Pericam;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Analysis of IP3 receptors in and out of cells

Keywords: پچ گیر; IP3 receptor; Ca signaling; TIRF microscopy; Patch clamp;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Voltage clamp methods for the study of membrane currents and SR Ca2+ release in adult skeletal muscle fibres

Keywords: پچ گیر; Skeletal muscle; Excitation; Contraction; Charge movement; Ca2+ current; Ca2+ transients; Voltage clamp; Patch clamp; Whole-cell configuration

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2012 سفارش ترجمه

Electrophysiological analysis of vulnerability to experimental ischemia in neonatal rat spinal ventral horn neurons

Keywords: پچ گیر; Patch clamp; Spinal cord ischemia; Spinal motoneuron

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Patch clamp analysis of the respiratory chain in Bacillus subtilis

Keywords: پچ گیر; GP; giant protoplast; GV; giant provacuole; EtBr; ethidium bromide; HQNO; 2-heptyl-4-hydroxyquinoline-N-oxide; Patch clamp; Respiratory chain; Bacillus subtilis; Giant protoplast;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

N-butyryl-homoserine lactone, a bacterial quorum-sensing signaling molecule, induces intracellular calcium elevation in Arabidopsis root cells

Keywords: پچ گیر; Arabidopsis thaliana; Calcium ion; N-butyryl-homoserine lactone; Patch clamp; Ca2+ influx;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay

Keywords: پچ گیر; KCNQ; Kv7; Patch clamp; Stable cell line; Thallium flux; 86Rubidium flux; Potassium channel opener; High-throughput screening;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Nonsense-mediated mRNA decay caused by a frameshift mutation in a large kindred of type 2 long QT syndrome

Keywords: پچ گیر; Long QT syndrome; Mutation; Nonsense-mediated mRNA decay; Patch clamp; Potassium channelhERG, human ether-a-go-go-related gene; HPH, hygromycin B phosphotransferase; IKr, rapid component of delayed rectifier potassium current; LQT2, long QT syndrome type

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Is mPTP the gatekeeper for necrosis, apoptosis, or both?

Keywords: پچ گیر; CsA; cyclosporine A; ROS; reactive oxygen species; MPT; mitochondrial permeability transition; MOMP; mitochondrial outer membrane permeabilization; iMACs; inhibitors of MAC; mPTP, mitochondrial permeability transition pore; MAC, mitochondrial apoptosis-in

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of nonsense-mediated mRNA decay by antisense morpholino oligonucleotides restores functional expression of hERG nonsense and frameshift mutations in long-QT syndrome

Keywords: پچ گیر; Nonsense-mediated mRNA decay; Potassium channel; Patch clamp; Morpholino, long-QT syndrome;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Reduced gain of excitation–contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction

Keywords: پچ گیر; Myotubes; Calcium imaging; Patch clamp; Retrograde signal; Orthograde signal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Bilirubin facilitates depolarizing GABA/glycinergic synaptic transmission in the ventral cochlear nucleus of rats

Keywords: پچ گیر; Bilirubin; Excitotoxicity; Calcium; PKA; Reversal potential; Patch clamp;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Multiple effects of allopregnanolone on GABAergic responses in single hippocampal CA3 pyramidal neurons

Keywords: پچ گیر; Neurosteroid; Allopregnanolone; Cl− conductance; GABAA receptors; Hippocampus; Patch clamp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

Keywords: پچ گیر; Cardiotoxicity; hERG; Long QT syndrome; NTP 1408 library; Patch clamp; qHTS; Tetra-n-octylammonium bromide; Thallium influx

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه