
Rearrangement of only one human IGHV gene is sufficient to generate a wide repertoire of antigen specific antibody responses in transgenic mice
Keywords: CDR-IMGT; complementarity determining region; FR-IMGT; framework region; IG; immunoglobulin; PBMC; peripheral blood mononuclear cells; Somatic hypermutation; Human IG transgenes; Immunoglobulin; Hybridomas; Monoclonal antibodies;