Keywords: Fundulus heteroclitus; Oxidative phosphorylation; Benzo [α] pyrene; PCB126; Elizabeth River
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Delayed effects of developmental exposure to low levels of the aryl hydrocarbon receptor agonist 3,3â²,4,4â²,5-pentachlorobiphenyl (PCB126) on adult zebrafish behavior
Keywords: Zebrafish; PCB126; Dioxin; Developmental neurotoxicity; Anxiety; Habituation;
Progression of micronutrient alteration and hepatotoxicity following acute PCB126 exposure
Keywords: Micronutrients; Metals; Homeostasis; PCB126; Time Course; AhR;
Theoretical perspectives on the mechanism and kinetics of the OH radical-initiated gas-phase oxidation of PCB126 in the atmosphere
Keywords: PCB126; OH radicals; Oxidation mechanism; Degradation products; Rate constants
Early life exposure to PCB126 results in delayed mortality and growth impairment in the zebrafish larvae
Keywords: Zebrafish; Early life stages; Delayed effects; Sublethal effects; Growth; PCB126;
Regulation of Ahr signaling by Nrf2 during development: Effects of Nrf2a deficiency on PCB126 embryotoxicity in zebrafish (Danio rerio)
Keywords: Ahr; aryl hydrocarbon receptor; Ahrr; aryl hydrocarbon receptor repressor; ARE; antioxidant response element; Cyp1a; cytochrome P540 1a; DLC; dioxin-like compound; DMSO; dimethyl sulfoxide; dpf; days post fertilization; hpf; hours post fertilization; Keap
Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions
Keywords: AHR; aryl hydrocarbon receptor; Ahr2; aryl hydrocarbon receptor 2; APC; adenomatosis polyposis coli; AZP; 1-azakenpaullone; CKIα; casein kinase Iα; CYP1; cytochrome P450 1; DLCs; dioxin-like compounds; DMSO; dimethyl sulfoxide; dpf; days post-fertilizat
A rapid in vivo zebrafish model to elucidate oxidative stress-mediated PCB126-induced apoptosis and developmental toxicity
Keywords: PCB126; 3,3â²,4,4,5-pentachlorobiphenyl; AhR; aryl hydrocarbon receptor; NAC; N-acetylcysteine; SOD; superoxide dismutase; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling; HPLC; high-performance liquid chromatography; GSH; gl
A simple and reliable in vivo EROD activity measurement in single Fundulus heteroclitus embryo and larva
Keywords: Ethoxyresorufin-O-deethylase; EROD; Fundulus heteroclitus; Embryo; Larva; PCB126
Relative potency of PCB126 to TCDD for sublethal embryotoxicity in the mummichog (Fundulus heteroclitus)
Keywords: Fundulus heteroclitus; PCB126; TEF; EROD; Behavior; PCR;
PCB126 induces apoptosis of chondrocytes via ROS-dependent pathways
Keywords: PCB126; Chondrocyte; Arthritis; Apoptosis; Reactive oxygen species; Nitric oxide; NF-kB;
Estrogen receptor-hijacking by dioxin-like 3,3â²4,4â²,5-pentachlorobiphenyl (PCB126) in salmon hepatocytes involves both receptor activation and receptor protein stability
Keywords: PCB126; AhR; Estrogen receptor; Interactions; Inhibitors;
Effects of polychlorinated biphenyls on liver function and sexual characteristics in Japanese medaka (Oryzias latipes)
Keywords: Japanese medaka; Microarray; Liver; PCB126; KC-400; Demasculinization;
Structural features of cytochrome P450 1A associated with the absence of EROD activity in liver of the loricariid catfish Pterygoplichthys sp.
Keywords: AHR; Aryl hydrocarbon receptor; BNF; Ã-naphthoflavone; CYP1A; Cytochrome P450 1A; DMBA; 7,12-dimethylbenz[α]anthracene; DMSO; Dimethyl sulfoxide; ER; Ethoxyresorufin; EROD; Ethoxyresorufin-O-deethylase; i.p.; intraperitoneally; ITS; internal transcribed
Embryonic exposure to environmentally relevant concentrations of PCB126 affect prey capture ability of Fundulus heteroclitus larvae
Keywords: PCB126; Fish larvae; Fundulus heteroclitus; Behavior; EROD
Characterizing non-constant relative potency
Keywords: CI; confidence interval; ED50; median effective dose; EROD; 7-ethoxyresorufin-O-deethylase; NTP; National Toxicology Program; PCB126; 3,3â²,4,4â²,5-pentachlorobiphenyl; PeCDF; 2,3,4,7,8-pentachlorodibenzofuran; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin;
PCB126 enhanced the genotoxicity of BaP in HepG2 cells by modulating metabolic enzyme and DNA repair activities
Keywords: PCB126; Benzo(a)pyrene; CYP1A1; MN; NER; DNA damage repair
Effects of 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) on vertebral bone mineralization and on thyroxin and vitamin D levels in Sprague–Dawley rats
Keywords: PCB126; Bone mineral density; TEM; FTIR; Vitamin D; Thyroxin
Cytochrome P450 1D1: A novel CYP1A-related gene that is not transcriptionally activated by PCB126 or TCDD
Keywords: Development; CYP1D1; AHR; PCB126; TCDD; Zebrafish; Embryo; Vertebrate toxicology; Oxidative biotransformationAHR, aromatic hydrocarbon receptor; ARNT, aryl hydrocarbon receptor nuclear translocator; Ct, threshold cycle; CYP, cytochrome P450; dpf, days pos
In vivo and in vitro effects of PCB126 and PCB153 on rat testicular androgenesis
Keywords: PCB126; PCB153; Rat Leydig cells; Androgenesis
Alteration of gene expression profiles in the brain of Japanese medaka (Oryzias latipes) exposed to KC-400 or PCB126
Keywords: Japanese medaka; Microarray; Brain; PCB126; KC-400
Neurobehavioral assessment of rats exposed to low doses of PCB126 and methyl mercury during development
Keywords: PCB126; Methyl mercury; Food contaminants; Developmental neurotoxicity; Hyperactivity
CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3â²,4,4â²,5-pentachlorobiphenyl
Keywords: PCBs; polychlorinated biphenyls; PCB126; 3,3â²,4,4â²,5-pentachlorobiphenyl; DMBA; 7,12-dimethylbenz[a]anthracene; PBS; phosphate-buffered saline; PCNA; proliferation cell nuclear antigen; ERestrogen receptor α; E2; 17-beta-estradiol; AhR; aryl hydrocar