Keywords: PD، بیماری پارکینسون; Airway management; Cough; Parkinson disease; Rehabilitation; Respiratory aspirationH&Y, Hoehn and Yahr; PAS, penetration aspiration scale; PD, Parkinson disease; PEFR, peak expiratory flow rate; VFSS, videofluoroscopic swallowing study
مقالات ISI PD، بیماری پارکینسون (ترجمه نشده)
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Keywords: PD، بیماری پارکینسون; AD, Alzheimer’s disease; Aβ, β amyloid; PD, Parkinson disease; l-DOPA, l-dihydroxyphenylalanine; LBs, Lewy bodies; DA, dopamine; APP, amyloid precursor protein; CVD, cardiovascular diseaseNeurological disorders; Alzheimer’s disease; Parkinson disease; Car
Keywords: PD، بیماری پارکینسون; Automobile driving; Multiple sclerosis; Physician; RehabilitationAD, Alzheimer disease; MS, multiple sclerosis; PABAK, prevalence-adjusted and bias-adjusted kappa; PD, Parkinson disease
Keywords: PD، بیماری پارکینسون; Deep brain stimulation; Effect size; Levodopa; Parkinson disease; Prognosis; Subthalamic nucleusη2, Effect size; ADL, Activities of daily living; DBS, Deep brain stimulation; LED, Levodopa-equivalent dose; LD, Levodopa; PD, Parkinson disease; PIGD, Postur
Keywords: PD، بیماری پارکینسون; Accelerometer; Activity tracking; Connected devices; Deep brain stimulation; Monitoring; Movement disorders; Parkinson diseaseDBS, Deep brain stimulation; FOG, Freezing of gait; GPi, Globus Pallidus internus; PD, Parkinson disease; STN, Subthalamic nucleu
Keywords: PD، بیماری پارکینسون; PD, Parkinson disease; QoL, quality of life; MDS-UPDRS, Movement Disorders Society Unified Parkinson Disease Rating Scale; ADLs, activities of daily living; PDQ-39, Parkinson's Disease Questionnaire-39; SF-12, 12-Item Short Form Health Survey; SF-36, 36-I
Keywords: PD، بیماری پارکینسون; Assistive devices; Gait disorders, neurologic; Parkinson disease; Proprioception; Rehabilitation; TouchH&Y, Hoehn and Yahr; PD, Parkinson disease
Keywords: PD، بیماری پارکینسون; Gait; Parkinson disease; RehabilitationCGT, conventional gait training; PD, Parkinson disease; PIGD, postural instability and gait difficulty; PWSTT, partial weight-supported treadmill training; UPDRS, Unified Parkinson Disease Rating Scale
Keywords: PD، بیماری پارکینسون; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; LRRK2, leucine-rich repeat kinase 2; HTRA2, high temperature requirement protein A2; PD, Parkinson disease; PINK1, PTEN-induced putative kinase 1; IMS, intermembrane space; OMM, outer mitochondrial membr
Keywords: PD، بیماری پارکینسون; NMF, non-motor fluctuations; PD, Parkinson disease; MF, motor fluctuations; HFS-STN, high frequency stimulation of the subthalamic nucleus; LEDD, levodopa equivalent daily-dose; PDD, Parkinson's disease dementia; COMT, catechol-O-methyltransferaseNon-moto
Keywords: PD، بیماری پارکینسون; Comorbidity; Parkinson disease; Postural balance; RehabilitationCIRS-G, Cumulative Illness Rating Scale-Geriatric; Mini-BESTest, Mini-Balance Evaluation Systems Test; OHSU, Oregon Health & Science University; PD, Parkinson disease
Keywords: PD، بیماری پارکینسون; AD, Alzheimer Disease; CHB, Chinese Han Beijing; CVD, cardiovascular disease; GWAS, genome-wide association study; MAF, minor allele frequency; OR, odds ratio; PD, Parkinson Disease; PCR, polymerase chain reaction; SNP, single nucleotide polymorphism.Card
Keywords: PD، بیماری پارکینسون; AUROC, area under the receiver operating characteristic curve; HC, healthy control; HY, Hoehn and Yahr; PD, Parkinson disease
Phage M13 for the treatment of Alzheimer and Parkinson disease
Keywords: PD، بیماری پارکینسون; AD, Alzheimer disease; PD, Parkinson disease; G3P, Gene 3 product; CED, Convection-enhanced-deliveryBacteriophage M13; Alzheimer disease; Parkinson disease
The C-terminal α-helices of mammalian Hsc70 play a critical role in the stabilization of α-synuclein binding and inhibition of aggregation
Keywords: PD، بیماری پارکینسون; Alpha synuclein; Hsc70 molecular chaperone; Aggregation; Amyloid fibrilα-syn, alpha synuclein; Hsp70, heat shock protein 70; PD, Parkinson disease; ThT, thioflavine T; DLS, dynamic light scattering; RH, hydrodynamic radius; AFM, atomic force microscopy; P
DJ-1 protects against undernutrition-induced atrophy through inhibition of the MAPK–ubiquitin ligase pathway in myoblasts
Keywords: PD، بیماری پارکینسون; DJ-1−/−, DJ-1-knockout; ERK, extracellular signal-regulated kinase; MAPK, mitogen-activated protein kinase; MuRF-1, muscle-specific RING finger-1; NC, NCBI; Ov-DJ-1, DJ-1-overexpressed cells; Ox-DJ-1, oxidized DJ-1; PD, Parkinson disease; SAPK/JNK, stres
The identification of dysfunctional crosstalk of pathways in Parkinson disease
Keywords: PD، بیماری پارکینسون; PD, Parkinson disease; DEGs, differentially expressed genes; LRRK2, leucine-rich repeat kinase 2; PINK1, PTEN-induced putative kinase 1; PARK, parkin; GBA, glucocerebrosidase; UCHL1, ubiquitin carboxyl-terminal esterase L1; SNCA, alpha-synuclein; GEO, Gen
Psoriasis is associated with an increased risk of parkinsonism: A population-based 5-year follow-up study
Keywords: PD، بیماری پارکینسون; autoimmune disease; cohort study; epidemiology; Parkinson disease; parkinsonism; psoriasisCI, confidence interval; HR, hazard ratio; IL, interleukin; LHID, Longitudinal Health Insurance Database 2000; NHI, National Health Insurance; PD, Parkinson disease
Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity
Keywords: PD، بیماری پارکینسون; α-syn, α-synuclein; PD, Parkinson disease; LBs, Lewy bodies; GD, Gaucher disease; GCase, glucocerebrosidase; WT, wild-type; α-glu A, acid α-glucosidase; N15, α-syn peptide residues 1–15; C23, α-syn peptide residues 118–140; MES, 2-(N-morpholino)ethanesulf
Deep Brain Stimulation in the Treatment of Obsessive-Compulsive Disorder
Keywords: PD، بیماری پارکینسون; DBS; OCD; StereotaxyCBT, Cognitive-behavioral psychotherapy; DBS, Deep brain stimulation; IC, Internal capsule; ITP, Inferior thalamic peduncle; NA, Nucleus accumbens; OCD, Obsessive-compulsive disorder; PD, Parkinson disease; STN, Subthalamic nucleus; VC
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration
Keywords: PD، بیماری پارکینسون; L-DOPA, levodopa; PD, Parkinson disease; COMT, catechol-O-methyltransferase; 3-OMD, 3-O-methyldopa; CNS, central nervous system; H2-DCF-DA, 2′,7′-dichlorofluorescein diacetate; AdoMet, S-adenosyl-L-methionine; ROS, reactive oxygen species; MTT, 3-(4,5-dim
Number of CAG repeats in POLG1 and its association with Parkinson disease in the Norwegian population
Keywords: PD، بیماری پارکینسون; PD, Parkinson disease; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; POLG, polymerase gamma; UPDRS, unified Parkinson disease rating scale; HY, Hoehn and Yahr scale; PIGD, postural instability and gait difficulty; TD, tremor dominantParkinsonism; Po
Thalamic cholinergic innervation is spared in Alzheimer disease compared to parkinsonian disorders
Keywords: PD، بیماری پارکینسون; PPN, pedunculopontine nucleus; LDTC, laterodorsal tegmental complex; PET, positron emission tomography; [11C]PMP, AChE [11C]-methyl-4-piperidinyl propionate; AD, Alzheimer disease; PD, Parkinson disease; PDD, Parkinson disease with dementia; DLB, dementia
Transcranial magnetic brain stimulation: Therapeutic promises and scientific gaps
Keywords: PD، بیماری پارکینسون; DLPFC, Dorsolateral prefrontal cortex; FDA, (US) Food and Drug Administration; LTP, Long term potentiation; MEP, Motor evoked potential; OCD, Obsessive compulsive disorder; PTSD, Posttraumatic stress disorder; PD, Parkinson disease; rTMS, Repetitive trans
Rotenone activates phagocyte NADPH oxidase by binding to its membrane subunit gp91phox
Keywords: PD، بیماری پارکینسون; MPP+, 1-methyl-4-phenylpyridinium ion; WST-1, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium; DPI, diphenyleneiodonium; PD, Parkinson disease; PHOX, phagocyte NADPH oxidase; PMA, phorbol 12-myristate 13-acetate; ROS, reactive oxyg
Oxidatively generated DNA damage after Cu(II) catalysis of dopamine and related catecholamine neurotransmitters and neurotoxins: Role of reactive oxygen species
Keywords: PD، بیماری پارکینسون; AD, Alzheimer disease; PD, Parkinson disease; ROS, reactive oxygen species; nDNA, nuclear DNA; mtDNA, mitochondrial DNA; ST-DNA, salmon testis DNA; SOD, superoxide dismutase; TBP, N-tert-butyl-α-phenylnitrone; TMP, 2,2,6,6-tetramethyl-4-piperidone; PEI, p
Different sub-cellular localization of alpha-synuclein in the C57BL\6J mouse's central nervous system by two novel monoclonal antibodies
Keywords: PD، بیماری پارکینسون; α-Syn, alpha-synuclein; CNS, central nervous system; ChAT, choline acetyltransferase; PB, phosphate-buffered; PBS, phosphate-buffered saline; PBST, phosphate-buffered saline containing 0.3% Triton X-100; PD, Parkinson disease; PFA, paraformaldehyde fixati
Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modifies Kinase and GTP-Binding Activities
Keywords: PD، بیماری پارکینسون; dardarin; PARK8; Parkinson disease; neurodegeneration; serine/threonine kinaseLRRK2, leucine-rich repeat kinase 2; PD, Parkinson disease; GTPase, guanosine triphosphatase; ETD, electron transfer dissociation; CID, collision-induced dissociation; WT, wild
Successful treatment with Yokukansan for behavioral and psychological symptoms of Parkinsonian dementia
Keywords: PD، بیماری پارکینسون; BPSD, Behavioral and psychological symptoms of dementia; PD, Parkinson disease; PDD, Parkinson disease with dementia; NPI, Neuropsychiatric Inventory; AD, Alzheimer disease; DLB, dementia with Lewy bodies; GABA, gamma-aminobutyric acid; UK, United Kingdom
Olfactory loss and nigrostriatal dopaminergic denervation in the elderly
Keywords: PD، بیماری پارکینسون; AASDDa, ge-associated striatal dopaminergic denervation; DAT, dopamine transporter; MMSE, Mini-Mental State Examination; PD, Parkinson disease; AD, Alzheimer disease; PET, positron emission tomography; UPDRS, Unified Parkinson's Disease Rating Scale; UPSI
Responsiveness of motor and nonmotor symptoms of Parkinson disease to dopaminergic therapy
Keywords: PD، بیماری پارکینسون; PD, Parkinson disease; PHQ-15, 15-item Patient Health Questionnaire; WOQ-9, 9-item, Wearing-Off Questionnaire; WOQ-19, 19-question Wearing-Off QuestionnaireDopamine; Dyskinesia; Motor fluctuations; Nonmotor; Somatization; Wearing off
Human PON1, a biomarker of risk of disease and exposure
Keywords: PD، بیماری پارکینسون; CPF, chlorpyrifos; CPO, chlorpyrifos oxon; DZ, diazinon; DZO, diazoxon; PO, paraoxon; PD, Parkinson disease; PON1, paraoxonase 1; PON2, paraoxonase 2; PON3, paraoxonase 3; PCR, polymerase chain reaction; tgHuPON1R192, transgenic human PON1R192; tgHuPON1Q1
Fibroblast growth factor 9 upregulates heme oxygenase-1 and γ-glutamylcysteine synthetase expression to protect neurons from 1-methyl-4-phenylpyridinium toxicity
Keywords: PD، بیماری پارکینسون; GSH, glutathione; ROS, reactive oxygen species; γ-GCSc, γ-glutamylcysteine synthetase catalytic subunit; γ-GCSm, γ-glutamylcysteine synthetase modifier subunit; HO-1, heme oxygenase-1; PD, Parkinson disease; FGF, fibroblast growth factor; MPP+, 1-methyl-4
Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: Modulation by the Nrf2/Trx axis
Keywords: PD، بیماری پارکینسون; ASK1, apoptosis signal-regulating kinase 1; PD, Parkinson disease; PQ, paraquat; JNK, c-Jun N-terminal kinase; PBS, phosphate-buffered saline; siRNA, small interfering RNA; PVDF, polyvinylidene difluoride; HE, hydroethidine; Eth, ethidium; Trx, thioredoxi
Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: Implications for iron-related dopaminergic neuron degeneration
Keywords: PD، بیماری پارکینسون; AM, aminochrome; CV, column volume; DA, dopamine; DFO, deferoxamine; GSH, glutathione; GSSG, glutathione disulfide; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; SN, substantia nigra; PD, Parkinson disease; ROS, reactive oxygen specie
Six-Minute Walk Distance in Persons With Parkinson Disease: A Hierarchical Regression Model
Keywords: PD، بیماری پارکینسون; Gait; Parkinson disease; Rehabilitation; WalkingBBS, Berg Balance Scale; FOGQ, Freezing of Gait Questionnaire; HY, Hoehn and Yahr; ICC, intraclass correlation coefficient; PD, Parkinson disease; TUG, Timed Up & Go; 6MWD, six-minute walk distance; 6MWT, si
Biphasic effect of apomorphine, an anti-parkinsonian drug, on bladder function in rats
Keywords: PD، بیماری پارکینسون; bladder; lower urinary tract; urodynamics; apomorphine; Parkinson disease; dopamineBC, bladder capacity; DCI, decarboxylase inhibitor; MP, maximum bladder contraction pressure; MV, micturition volume; PD, Parkinson disease; PVR, postvoid residual; TP, thr
Cytotoxicity of dopaminochrome in the mesencephalic cell line, MN9D, is dependent upon oxidative stress
Keywords: PD، بیماری پارکینسون; DAC, dopaminochrome; SNpc, substantia nigra pars compacta; PD, Parkinson disease; GSH, reduced glutathione; GSSG, oxidized glutathione; DHE, dihydroethidium; DMEM, Dulbecco's modified Eagle's MediumNeurodegeneration; Parkinson disease; Dopamine; Glutathio
Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies
Keywords: PD، بیماری پارکینسون; PD, Parkinson disease; DLB, dementia with Lewy bodies; mtNOS, mitochondrial nitric oxide synthase; Mn-SOD, Mn-superoxide dismutaseComplex I; mtNOS; Mn-SOD; Cytochrome content; Oxidative damage; Human brain mitochondria; Free radicals
Improvement of Gaze Control After Balance and Eye Movement Training in Patients With Progressive Supranuclear Palsy: A Quasi-Randomized Controlled Trial
Keywords: PD، بیماری پارکینسون; Eye movements; Rehabilitation; Supranuclear palsy, progressive; Reflex, vestibulo-ocularANOVA, analysis of variance; FEF, frontal eye field; PD, Parkinson disease; PSP, progressive supranuclear palsy; RMS, root-mean-square; UPDRS, Unified Parkinson Diseas
Prion protein protects against zinc-mediated cytotoxicity by modifying intracellular exchangeable zinc and inducing metallothionein expression
Keywords: PD، بیماری پارکینسون; AD, Alzheimer disease; Dox, doxycycline; MT, metallothionein; PBS, phosphate buffer saline; PD, Parkinson disease; PrPC, cellular isoform of prion protein; PrPSc, scrapie isoform of prion protein; S.D., standard deviationPrion protein; Zinc ions; Metallot
In inclusion-body myositis muscle fibers Parkinson-associated DJ-1 is increased and oxidized
Keywords: PD، بیماری پارکینسون; Aβ, amyloid-β; AD, Alzheimer disease; DNP, 2,4-dinitrophenyl; DNPH, 2,4-dinitrophenylhydrazine; PD, Parkinson disease; qRT-PCR, quantitative real-time polymerase chain reaction; s-IBM, sporadic inclusion-body myositis; α-syn, α-synucleinDJ-1; Inclusion-bo
Magnesium exerts both preventive and ameliorating effects in an in vitro rat Parkinson disease model involving 1-methyl-4-phenylpyridinium (MPP+) toxicity in dopaminergic neurons
Keywords: PD، بیماری پارکینسون; Mg, magnesium; MPP+, 1-methyl-4-phenylpyridinium; PD, Parkinson disease; TH, tyrosine hydroxylaseMagnesium; 1-methyl-4-phenylpyridinium; Dopaminergic neuron; Ventral mesencephalic–striatal co-culture; Parkinson disease
Insights into the effects of α-synuclein expression and proteasome inhibition on glutathione metabolism through a dynamic in silico model of Parkinson's disease: validation by cell culture data
Keywords: PD، بیماری پارکینسون; PD, Parkinson disease; SN, substantia nigra; α-syn, α-synuclein; CI, mitochondrial complex I; RS, reactive species; ROS, reactive oxygen species; RNS, reactive nitrogen species; GSH, glutathione reduced; GSSG, glutathione oxidized; GCL, γ-glutamyl cystein
Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration
Keywords: PD، بیماری پارکینسون; Aβ, amyloid-beta; AD, Alzheimer's disease; CNS, central nervous system; CSF, cerebral spinal fluid; Foxp3, forkhead transcription factor; MFI, mean flourescence intensity; PD, Parkinson disease; Treg, regulatory T cells.Immune regulation; Alzheimer's dise
One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime
Keywords: PD، بیماری پارکینسون; DA, dopamine; DBH, dopamine β-hydroxylase; CGG, chromaffin granule ghosts; EPR, electron paramagnetic resonance; NA, noradrenaline; PD, Parkinson disease; ROS, reactive oxygen speciesCatecholamines; Semiquinone free radicals; Electron paramagnetic resonan
Restless Legs Syndrome : A Clinical Update
Keywords: PD، بیماری پارکینسون; diagnosis; Parkinson disease; restless legs syndrome; treatmentBRA, benzodiazepine receptor agonist; PD, Parkinson disease; PLMS, periodic limb movements in sleep; RLS, restless legs syndrome; SSRI, serotonin reuptake inhibitor