Keywords: MMPs; Matrix metalloproteinases; ECM; extracellular matrix; TSP-2; Thrombospondin-2; FAK; focal adhesion kinase; Akt; protein kinase B; NF-κB; nuclear factor kappa B; Ig; immunoglobulin; DN; dominant negative; shRNA; short hairpin RNA; TCGA; The Cancer G
مقالات ISI (ترجمه نشده)
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Keywords: Equivalent single phase; Gas condensate reservoirs; Production decline type curves; Rate transient analysis; Two-phase production data analysis; BDF; boundary dominated flow; CCE; constant composition expansion; EUR; expected ultimate recovery; GCR; gas c
Keywords: Polymeric nanomedicines; Peptide; Cancer therapy; Therapeutic delivery; AF; aminoflavone; ANG; angiopep-2; BBB; blood brain barrier; BCECs; brain capillary endothelial cells; BP; bortezomib-pinanediol; bPEISS; bioreducible branched polyethylenimine; BPLP;
Keywords: Cardiovascular diseases; inflammation; prenatal inflammatory exposure; maternal immune activation; developmental reprogramming; NF-κB; ACE; Angiotensin-converting enzyme; ACTH; Adrenocorticotropic hormone; Ang II; Angiotensin II; ApoE; Apolipoprotein E;
Keywords: Systemic lupus erythematosus; Lupus nephritis; Podocytes; Lupus mice model; Immunosuppressive drugs; CD2AP; CD2-associated protein; TRPC; transient receptor potential canonical; IL; interleukin; TNFα; tumoral necrosis factor-alpha; IFNγ; interferon-gamm
Keywords: DTC; dithiocarbamates; EGCG; (-)-epigallocatechin-3-gallate; DSF; disulfiram; DEDTC; diethyldithiocarbamate; PDTC; pyrrolidine dithiocarbamate; SOD; superoxide dismutase; MT; metallothionein; ROS; reactive oxygen species; γH2AX; histone H2AX; ALT; alanin
Keywords: ALS; acid-labile subunit; CIS; cytokine-inducible SH2-containing protein; E2; estradiol; ER; endoplasmic reticulum; ERK; extracelular regulated kinase; ESPE; European Society for Pediatric Endocrinology; GH; growth hormone; GHBP; growth hormone binding pr
Keywords: EGF; epidermal growth factor; DPBS; dulbecco's phosphate-buffered saline; DMEM; dulbecco's modified eagle medium; TBST; Tween 20/Tris-buffered saline; TGF-β1; transforming growth factor beta1; MAPK; mitogen-activated protein kinases; ERK; extracellular r
Keywords: Antioxidant activity; Free radical; Inflammation; Oxidative stress; PDTC; UVB irradiation
Keywords: AII; angiotensin II; CNPase; 2â²,3â²-cyclic nucleotide 3â²-phosphodiesterase; Ara-C; cytosine-β-d-arabino-furanoside; DIV; days in vitro; DMT1; divalent metal transporter 1; Fp1; ferroportin 1; IL-1 β; Interleucin 1 β; NAC; N-acetyl-cysteine; PD; Pa
Keywords: 7,8-DHF; 7,8-dihydroxyflavone; Aβ; amyloid beta; AchE; acetylcholine-esterase; ABCA1; ATP-binding cassette transporter 1; APP; amyloid precursor protein; Akt; protein kinase B; ApoE; apolipoprotein E; AAV/Aβ; adeno-associated viral vector carrying Aβ c
Polysaccharide isolated from seeds of Plantago asiatica L. induces maturation of dendritic cells through MAPK and NF-κB pathway
Keywords: CD; cluster of differentiation; DCs; dendritic cells; ERK; extracellular signal regulated kinases; TNF; tumor necrosis factor; IL; interleukin; JNK; c-Jun amino-terminal kinases; MAPK; mitogen-activated protein kinase; NF-κB; nuclear factor κB; PAMPs; p
C-phycocyanin reduces inflammation by inhibiting NF-κB activity through downregulating PDCD5 in lipopolysaccharide-induced RAW 264.7 macrophages
Keywords: C-phycocyanin; Anti-inflammation; Dynamic proteomics; Programmed cell death 5 protein; NF-κB pathway; C-PC; C-phycocyanin; SiLAD; 35S in vivo/vitro labelling analysis for dynamic proteomic; PDCD5; programmed cell death 5 protein; NF-κB; nuclear factor Î
The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells
Keywords: AKT; protein kinase B (or PKB); ATC; anaplastic thyroid carcinoma; BRAF; v-Raf murine sarcoma viral oncogene homolog B (or B-RAF); EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase (or mitogen-activated protein kinase 1);
Rig-I is involved in inflammation through the IPS-1/TRAF6 pathway in astrocytes under chemical hypoxia
Keywords: RIG-I; retinoic acid-inducible gene I; IPS-1; interferon-β promoter stimulator-1; TRAF; TNF receptor-associated factor; PRRs; pattern recognition receptors; TLRs; toll-like receptors; NLRs; NOD-like receptors; RLRs; RIG-like receptors; MDA5; melanoma dif
The role and mechanism of KCa3.1 channels in human monocyte migration induced by palmitic acid
Keywords: BSA; bovine serum albumin; ELISA; enzyme linked immunosorbent assay; FBS; fetal bovine serum; FFAs; free fatty acids; HUVECs; human umbilical vein endothelial cells; MCP-1; monocyte chemoattractant protein-1; NF-κB; nuclear factor-κB; PA; palmitic acid;
The feedback loop of “EMMPRIN/NF-κB” worsens atherosclerotic plaque via suppressing autophagy in macrophage
Keywords: Atherosclerosis; Extracellular matrix metalloproteinase inducer; Macrophage autophagy; Nuclear factor kappa B; Vulnerable plaque; AMPK; Adenosine Monophosphate Activated Protein Kinase; ApoEÂ â/â; Â Apolipoprotein E-deficient; AS; atherosclerosis; CQ;
Inhibitive Effect of Resveratrol on the Inflammation in Cultured Astrocytes and Microglia Induced by Aβ1-42
Keywords: AD; Alzheimer's disease; Aβ; beta-amyloid; APC; antigen-presenting cell; BACE1; β-site APP cleaving enzyme 1; BBB; blood-brain barrier; CCK; cell-counting kit; CD40; cluster of differentiation 40; CNS; central nervous system; DAPI; 4â²,6-diamidino-
Microcystin induction small Maf protein involve in transcriptional regulation of GST from freshwater mussel Cristaria plicata
Keywords: Maf; musculoaponeurotic fibrosarcoma; GST; glutathione S-transferase; ARE; antioxidant response element; EpRE; electrophile response element; CNC; cap “n” collar; bZIP; basic region leucine zipper; Nrf2; nuclear factor erythroid-2p45-related factor 2;
Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF-κB activity
Keywords: Diclofenac; Acute kidney injury; PDTC; Oxidative stress; Cytokine; NF-κB;
Preparation of poly-ammonium/sodium dithiocarbamate for the efficient removal of chelated heavy metal ions from aqueous environments
Keywords: AOP; advanced oxidation process; COD; chemical oxygen demand; CA; citric acid; CA-Cu; citric acid-Cu; CA-Ni; citric acid-Ni; CA-Zn; citric acid-Zn; DTC; dithiocarbamate; DP; degrees of polymerization; EDTA; ethylenediaminetetraacetic acid; EDTA-Cu; ethyle
Curcumin Protects Against Chronic Stress-induced Dysregulation of Neuroplasticity and Depression-like Behaviors via Suppressing IL-1β Pathway in Rats
Keywords: ADF; actin-depolymerizing factor; CIN; chronophin; CNS; central nervous system; CUMS; chronic unpredictable mild stress; ELISA; enzyme-linked immunosorbent assay; LIMKs; LIM-kinases; MDD; major depressive disorder; mPFC; medial prefrontal cortex; PDTC; py
Regulation of CacyBP/SIP expression by NFAT1 transcription factor
Keywords: CacyBP/SIP; calcyclin binding protein/Siah-1 interacting protein; ChIP; chromatin immunoprecipitation; NFAT; nuclear factor of activated T cells; PAGE; polyacrylamide gel electrophoresis; PDTC; pyrrolidine dithiocarbamate; SDS; sodium dodecyl sulfate; Cac
Research paperMesenchymal stem cells derived from multiple myeloma patients protect against chemotherapy through autophagy-dependent activation of NF-κB signaling
Keywords: MM; multiple myeloma; MSCs; mesenchymal stem cells; BM; bone marrow; PDTC; pyrrolidinedithiocarbamate; MSCs; Autophagy; Apoptosis; Drug resistance;
High programmed death 1 expression on T cells in aplastic anemia
Keywords: PD-1; programmed death 1; AA; aplastic anemia; MNCs; mononuclear cells; BMHSCs; bone marrow hematopoietic stem cells; PBMCs; peripheral blood mononuclear cells; FCM; flow cytometry; PDTC; pyrrolidine dithiocarbamate; NF; nuclear factor; Aplastic anemia; P
Maspin inhibits macrophage phagocytosis and enhances inflammatory cytokine production via activation of NF-κB signaling
Keywords: Arg-1; arginase 1; CM; conditioned medium; FITC; fluorescein isothiocyanate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; iNOS; inducible nitric oxide synthase; IFN; interferon; IKK; inhibitor of NF-κB kinase; IκB; inhibitor of NF-κB; LPS; lipopoly
Honokiol, a potential therapeutic agent, induces cell cycle arrest and program cell death in vitro and in vivo in human thyroid cancer cells
Keywords: DTC; differentiated thyroid cancer; PDTC; poorly differentiated thyroid cancer; ATC; anaplastic thyroid cancer; FTC; follicular thyroid carcinoma; PTC; papillary thyroid carcinoma; PI3K; phosphoinositide 3-kinase; NF-κB; nuclear factor kappa B; EGFR; epi
Pyrrolidine dithiocarbamate (PDTC) inhibits inflammatory signaling via expression of regulator of calcineurin activity 1 (RCAN1): Anti-inflammatory mechanism of PDTC through RCAN1 induction
Keywords: PDTC; pyrrolidine dithiocarbamate; RCAN1; regulator of calcineurin 1; NF-κB; nuclear factor-κB; NFAT; nuclear factors of activated T cells; PDTC; Calcineurin; RCAN1; Inflammation;
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages
Keywords: FBS; foetal bovine serum; AuNPs; gold nanoparticles; FITC; fluorescein isothiocyanate; TLR; Toll-like receptor; Akt; protein kinase B; NF-κB; nuclear factor-κB; ERK; extracellular signal-regulated kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-acti
Inhibition of TRAF6-Ubc13 interaction in NFkB inflammatory pathway by analyzing the hotspot amino acid residues and protein-protein interactions using molecular docking simulations
Keywords: PPI; protein-protein interaction; PDTC; Pyrrolidine dithiocarbamate; NFkB; Nuclear Factor kappa B; IkB; Inhibitor of kappa; RING; Really Interesting New Gene; TRAF6; TNF receptor associated factor 6; IL1; Interleukin 1; Ubc13; Ubiquitin conjugating prot
Recent developments on optical and electrochemical sensing of copper(II) ion based on transition metal complexes
Keywords: AAS; atomic absorption spectroscopy; AIPE; aggregation-induced phosphorescent emission; bpy; 2,2â²-bipyridine; CT; charge transfer; DFT; density functional theory; DPA; dipicolylamine; EDTA; ethylenediaminetetraacetic acid; EPA; U.S. Environmental Protec
Substance P enhances tissue factor release from granulocyte-macrophage colony-stimulating factor-dependent macrophages via the p22phox/β-arrestin 2/Rho A signaling pathway
Keywords: ELISA; enzyme-linked immunosorbent assay; GM-CSF; granulocyte-macrophage colony-stimulating factor; GRK2; G protein-coupled receptor kinase 2; NK1R; neurokinin 1 receptor; PDTC; pyrrolidinedithiocarbamate; PKC; protein kinase C; Rho A; ras homolog gene fa
Research paperKindlin-2 promotes invasiveness of prostate cancer cells via NF-κB-dependent upregulation of matrix metalloproteinases
Keywords: siRNA; small interfering RNA; (NF)-κB; nuclear factor; MMP-9; metalloproteinase-9; PKD2; protein kinase D2; MMPs; matrix metalloproteinases; DMEM; Dulbecco's modified eagle medium; FBS; fetal bovine serum; PDTC; pyrrolidine dithiocarbamate; RIPA; radioim
MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2
Keywords: OA; osteoarthritis; miR-502-5p; microRNA-502-5p; IL-1β; interleukin -1 beta; TNFα; tumor necrosis factor alpha; TNFR; tumor necrosis factor receptor; TRAF2; TNF receptor-associated factor 2; ECM; extracellular matrix; MMP-13; matrix metalloproteinase-13
Oestrogen exerts anti-inflammation via p38 MAPK/NF-κB cascade in adipocytes
Keywords: LPS; lipopolysaccharides; MCP-1; monocyte chemoattractant protein-1; E2; 17β-estradiol; ERoestrogen; receptor; SB; SB203580; PDTC; pyrrolidine dithiocarbamate; PTX; pertussis toxin; WM; wortmannin; PPT; trisphenol; DPN; 2,3-bis-(4-hydroxyphenyl)-propioni
Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner
Keywords: HIF; Hypoxia-inducible Factor; IL-6; Interleukin 6; IRS1; Insulin Receptor Substrate 1; Jak; Januskinase; mTOR; Mammalian Target of Rapamycin; MEF; Mouse Embryonic Fibroblast; NF-κB; Nuclear Factor kappa B; n.s.; non-significant; MAPK; Mitogen-Activated
Tubular cell phenotype in HIV-associated nephropathy: Role of phospholipid lysophosphatidic acid
Keywords: HRPTC; human renal proximal tubular cells; PL A 1/2; phospholipase A 1/2; LysoPLD; lysophospholipase D; PDTC; pyrrolidine dithiocarbamate; DAG; di-acyl glycerol; CKD; chronic kidney disease; ESRD; end stage renal disease (ESRD); ECM; extracellular matrix;
PKCδ-iPLA2-PGE2-PPARγ signaling cascade mediates TNF-α induced Claudin 1 expression in human lung carcinoma cells
Keywords: CLDN1; claudin 1; TJ; tight junctions; PPARγ; peroxisome proliferator-activated receptor γ; TRAF-2; TNF-associated factor 2; FADD; Fas-associated protein with death domain; sPLA2; secreted phospholipase 2; cPLA2; cytosolic calcium dependent PLA2; iPLA2;
Sirtuin-6 inhibits cardiac fibroblasts differentiation into myofibroblasts via inactivation of nuclear factor κB signaling
Keywords: AAC; abdominal aortic constriction; Ang II; angiotensin II; CCK-8; Cell Counting Kit-8; CF; cardiac fibroblast; DAPI; 4â²,6-diamidino-2-phenylindol; ECM; extracellular matrix; EGFP; enhanced green fluorescent protein; EMSA; electrophoretic mobility shift
Suppression of prolactin signaling by pyrrolidine dithiocarbamate is alleviated by N-acetylcysteine in mammary epithelial cells
Keywords: Mammary epithelial cells; PDTC; Prolactin; Insulin; Signal transduction;
Immunomodulatory effect of Ganoderma atrum polysaccharide on CT26 tumor-bearing mice
Keywords: CRBC; Chicken red blood cells; G; Ganoderma; MΦ; peritoneal macrophages; PSG-1; Ganoderma atrum polysaccharide; PDTC; pyrrolidine dithiocarbamate; TLR; Toll-like receptor; Antitumor; Ganoderma atrum polysaccharide (PSG-1); Immunity; Macrophage;
IL-10 modulates serotonin transporter activity and molecular expression in intestinal epithelial cells
Keywords: GI; gastrointestinal; 5-HT; 5-hydroxytryptamine, serotonin; SERT; serotonin transporter; IBS; Irritable Bowel Syndrome; IBD; Inflammatory Bowel Diseases; IL-10; Interleukin-10; IL-10R; Interleukin-10 receptor; IL10RA; Interleukin-10 receptor subunit alpha
Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice
Keywords: Fr1; frontal brain cortex area 1; IL-1β; interleukin 1β; MCAO; middle cerebral arterial occlusion; NF-κB; nuclear transcription factor-κB; PDTC; pyrrolidine dithiocarbamate; SpO2; pulse oximeter oxygen saturation; TUNEL; terminal deoxynucleotidyl tran
The JNK/NFκB pathway is required to activate murine lymphocytes induced by a sulfated polysaccharide from Ecklonia cava
Keywords: CFSE; carboxy fluorescein diacetate succinimidyl ester; Con A; concanavalin A; E. cava; Ecklonia cava; ERK; extracellular signal-regulated kinases; DMSO; dimethylsulfoxide; ELISA; enzyme linked immunosorbent assay; EMSA; electrophoretic mobility shift ass
Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells
Keywords: MOR; mu opioid receptor; JNK; c-Jun NH2-terminal kinase; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated protein/extracellular signal-regulated kinase; NF-κB; nuclear factor-kappaB; DP; distal promoter; PP; proximal promoter; Oct-1; octame
Minimal NF-κB activity in neurons
Keywords: AP5; 2-amino-5-phosphonopentanoate; BDNF; brain-derived neurotrophic factor; BRN; mixed brain cells; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CxN; cortical neurons; DMEM; Dulbecco's modified Eagle's medium; EDTA; ethylenediaminetetraacetic acid; EG
Vitamin D in thyroid tumorigenesis and development
Keywords: 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 25-OHD3; 25-hydroxyvitamin D3; ATC; anaplastic thyroid cancer; CDK; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; CEA; carcinoembryogenic antigen; CT; calcitonin; CYP24A1; 24-hydroxylase; CYP27B
Inhibition on hepatitis B virus in vitro of lectin from Musca domestica pupa via the activation of NF-κB
Keywords: MPL; lectin from Musca domestica pupa; HBV; hepatitis B virus; NF-κB; nuclear factor-κB; HepG2.2.15; human hepatoma G2.2.15; PDTC; pyrrolidine dithiocarbamate; IL-2; interleukin-2; INF-γ; gamma interferon; IκB; nuclear factor-κB inhibitory κB; Lecti
NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells
Keywords: 15-LOX; 15-lipoxygenase; AD; Alzheimer's disease; CFH; complement factor H; HNG; human neuronal-glial; LPS; lipopolysaccharide; miRNA; micro RNA; PDTC; pyrollidine dithiocarbamate; SYN-2; (SYN-II, synapsin-2); TNFα; tumor necrosis factor alpha; TSPAN-12;
Pyrrolidine dithiocarbamate augments Hg2+-mediated induction of macrophage cell death via oxidative stress-induced apoptosis and necrosis signaling pathways
Keywords: HgCl2; PDTC; Apoptosis; Necrosis; Reactive oxygen species; Caspase 3/7