Pigment epithelium-derived factor gene loaded in cRGD-PEG-PEI suppresses colorectal cancer growth by targeting endothelial cells
Keywords: PEDF; PEG-PEI; cRGD; HUVECs; Gene therapy;
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Serum level of pigment epithelium-derived factor is a marker of atherosclerosis in humans
Keywords: PEDF; pigment epithelium-derived factor; EC; endothelial cell; FDG-PET; [18F]-fluorodeoxyglucose-positron emission tomography; IMT; intima-media thickness; BP; blood pressure; LDL-cholesterol; low-density lipoprotein-cholesterol; HDL-cholesterol; high-den
Pigment epithelium-derived factor inhibits advanced glycation end-products-induced cytotoxicity in retinal pericytes
Keywords: PEDF; AGE; Pericytes; Src kinase; Oxidative stress; Apoptosis; Diabetic retinopathyPEDF; AGE; Péricytes; Kinase Src; Stress oxidant; Apoptose; Rétinopathie diabétique
The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization
Keywords: Complement activation; Alternative pathway; Age-related macular degeneration; Choroidal neovascularization; VEGF; PEDF; Mouse model;
PEDF inhibits IL8 production in prostate cancer cells through PEDF receptor/phospholipase A2 and regulation of NFκB and PPARγ
Keywords: Ab; antibody; CRPC; Castration-Resistant Prostate Cancer; HRPC; Hormone-Refractory Prostate Cancer; IL8; interleukin-8; NFκB; Nuclear Factor Kappa-B; PPARγ; Peroxisome Proliferation Activated Receptor gamma; PEDF; Pigment Epithelium-Derived Factor; PEDF
The non-antibiotic properties of tetracyclines: Clinical potential in ophthalmic disease
Keywords: ARMD; age-related macular degeneration; CMT; chemically modified tetracyclines; CNV; choroidal neovascularization; KNV; corneal neovascularization; IL; interleukin; MMP; matrix metalloproteinase; MG; meibomian gland; NO; nitric oxide; PEDF; pigment-epithe
The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization
Keywords: Bone marrow; Stem cells; Angiogenesis; VEGF; PEDF
Pigment Epithelium-Derived Factor Blocks Tumor Extravasation by Suppressing Amoeboid Morphology and Mesenchymal Proteolysis
Keywords: PEDF; pigment epithelium-derived factor; MT1-MMP; membrane type-1 matrix metalloproteinase; PEDF-R; PNPLA2; LR; laminin receptor; AMT; amoeboid-to-mesenchymal transition;
Anti-chondrosarcoma effects of PEDF mediated via molecules important to apoptosis, cell cycling, adhesion and invasion
Keywords: PEDF; Chondrosarcoma; Apoptosis; Cell cycling; Invasion; Migration
Pigment epithelium-derived factor inhibits advanced glycation end product-elicited mesangial cell damage by blocking NF-κB activation
Keywords: AGE; Diabetic nephropathy; Oxidative stress; PEDF
Multiple neurotrophic effects of VEGF on cultured neurons
Keywords: PEDF; Amyloid beta; Apoptosis; Survival; p38 MAP kinase; Bcl-2; Caspase 3
Pigment epithelium-derived factor inhibits advanced glycation end products-induced retinal vascular permeability
Keywords: AGE-BSA; PEDF; Vascular permeability; PI3K/Akt; NADPH; ROS; ZO-1AGE-BSA, advanced glycation end products-bovine serum albumin; PEDF, pigment epithelium-derived factor; DR, diabetic retinopathy; VEGF, vascular endothelial growth factor; PI3K/Akt, phosphoin
Antiangiogenic properties of silver nanoparticles
Keywords: Bovine retinal endothelial cell; Vascular endothelial growth factor; Ag-NPs; PEDF; Angiogenesis
Proteomic analysis of cerebrospinal fluid from patients with idiopathic temporal lobe epilepsy
Keywords: apoE; apolipoprotein E; apoJ; apolipoprotein J; CSF; cerebrospinal fluid; DBP; vitamin D-binding protein; IGKV1-5; immunoglobulin kappa variable light chain 1-5; IGL@; immunoglobulin lambda light chain; LC-ESI-MS/MS; liquid chromatography electros
Low power laser treatment of the retina ameliorates neovascularisation in a transgenic mouse model of retinal neovascularisation
Keywords: photocoagulation; VEGF; oxygen; PEDF; FITC-dextran
Amphiregulin Induces the Alternative Splicing of p73 Into Its Oncogenic Isoform ÎEx2p73 in Human Hepatocellular Tumors
Keywords: Act D; actinomycin D; ADAM; a disintegrin and metalloproteinase; AQP3; aquaporin 3; AR; amphiregulin; ChIP; chromatin immunoprecipitation assay; Cirr; cirrhotic; EGFR; epidermal growth factor receptor; HCC; hepatocellular carcinoma; HL; healthy liver; JNK
Diabetic Macular Edema: Pathogenesis and Treatment
Keywords: AGEs; angiotensin II; blood retinal barrier; clinically significant macular edema; diabetic macular edema; intravitreal steroid injection; laser photocoagulation; leukostasis; micropulse sub-threshold laser; OCT; PEDF; PKC; RAGE; retinal thickness analyze
Increased serum pigment epithelium-derived factor levels in type 1 diabetic patients with diabetic retinopathy
Keywords: PEDF; Type 1 diabetes; Retinopathy;
Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL)
Keywords: PEDF; ATGL; Adiposome; Triglyceride; Liver
Decreased expression of pigment epithelium derived factor (PEDF), an inhibitor of angiogenesis, in placentas of unexplained stillbirths
Keywords: stillbirth; angiogenesis; placenta; PEDF
Promoter polymorphisms of the pigment epithelium-derived factor gene are associated with diabetic retinopathy
Keywords: DR; diabetic retinopathy; PDR; proliferative diabetic retinopathy; DME; diabetic macular edema; VEGF; vascular endothelial growth factor; PEDF; pigment epithelium-derived factor; SNP; single nucleotide polymorphism; NPDR; non-proliferative diabetic retino
Chitosan microparticles encapsulating PEDF plasmid demonstrate efficacy in an orthotopic metastatic model of osteosarcoma
Keywords: Chitosan; Microparticle; PEDF; Cancer; Gene delivery
Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson's disease
Keywords: Parkinson's disease; PEDF; VEGF; MPTP
Retinal and choroidal microangiopathies: Therapeutic opportunities
Keywords: Angiogenesis; Vascularization; IGF-1; IGF-1R; VEGF; VEGFR-1; VEGFR-2; SDF-1; γ-secretase; Delta-like ligand 4; PEDF; IGFBP-3; Protein kinase CK2; Endothelial progenitor cell; Hematopoietic stem cell; Proliferative retinopathy; CD34; CD14; CD133; Hypoxia;
Pigment epithelium-derived factor inhibits oxidative stress-induced cell death by activation of extracellular signal-regulated kinases in cultured retinal pigment epithelial cells
Keywords: PEDF; Oxidative stress; RPE; ARPE-19; ERK1/2
Pigment epithelium-derived factor protects retinal pigment epithelium from oxidant-mediated barrier dysfunction
Keywords: PEDF; RPE; H2O2; HSP27; p38; Actin; Occludin; N-cadherin
Vitreous and aqueous concentrations of proangiogenic, antiangiogenic factors and other cytokines in diabetic retinopathy patients with macular edema: Implications for structural differences in macular profiles
Keywords: VEGF; HGF; PEDF; growth factors; vitreous; aqueous; diabetic macular oedema; OCT
Contribution of VEGF and PEDF to choroidal angiogenesis: A need for balanced expressions
Keywords: VEGF; PEDF; Angiogenesis; CNV; PCV
Proteomic analysis of vitreous from diabetic macular edema
Keywords: proteomics; vitreous; diabetes; macular edema; PEDF; ApoA; Trip-11;
Expression of angiogenesis factors in human umbilical vein endothelial cells and their regulation by PEDF
Keywords: Angiogenesis; PEDF; VEGF; Thrombospondin-1; FGF-2; HUVECs; VEGF receptors; VEGF-R3; VEGF-C;
Pigment epithelium-derived factor induces pro-survival genes through cyclic AMP-responsive element binding protein and nuclear factor kappa B activation in rat cultured cerebellar granule cells: Implication for its neuroprotective effect
Keywords: pigment epithelium-derived factor; PEDF; pro-survival genes; neuronal apoptosis; transcription factors; signal transduction pathway; ALLN; N-acetyl-Leu-Leu-norleucinal; BSA; bovine serum albumin; CGCs; cerebellar granule cells; CRE; cyclic AMP-response el
Pigment epithelium-derived factor (PEDF)-induced apoptosis and inhibition of vascular endothelial growth factor (VEGF) expression in MG63 human osteosarcoma cells
Keywords: PEDF; Osteosarcoma; Apoptosis; Angiogenesis; VEGF
PEDF and the serpins: Phylogeny, sequence conservation, and functional domains
Keywords: PEDF; Serpins; Bioinformatics tools; Protein alignment; Reactive center loop; Peptides; Structure-function relationships; Heparin binding; Nuclear localization signal; Glycosylation;
Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
Keywords: A2E; N-retinyl-N-retinylidene ethanolamine; AA; arachidonic acid; AAV; adeno-associated virus; ABCR; ATP-binding cassette transporter retina; AIF; apoptosis inducing factor; AMD; age-related macular degeneration; AP-1; activator protein-1; AP24; Mr 24; 00