Keywords: پرامانپل; Perampanel; Levetiracetam; Efficacy; Tolerability; Adverse events;
مقالات ISI پرامانپل (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: پرامانپل; AED; antiepileptic drug; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; EIAED; enzyme-inducing antiepileptic drug; IGE; idiopathic generalised epilepsy; ILAE; International League Against Epilepsy; TEAE; treatment-emergent adverse event; Ant
Keywords: پرامانپل; Epilepsy; Antiepileptic drugs; Cognition; Perampanel; Lacosamide; Neuropsychology;
Keywords: پرامانپل; Epilepsy; Perampanel; Children; Adolescent; Efficacy; Tolerability;
Keywords: پرامانپل; AE; adverse event; AED; antiepileptic drug; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CBZ; carbamazepine; CYP; cytochrome P450; EIAED; enzyme-inducing antiepileptic drug; LOCF; last observation carried forward; OC; observed case; PB; ph
Keywords: پرامانپل; Perampanel; Audiogenic seizures; Genetically epilepsy prone rats; Tolerance; AMPA receptor antagonist; Clobazam;
Keywords: پرامانپل; Progressive myoclonic epilepsy; Sialidosis; Perampanel; NEU1 gene;
Keywords: پرامانپل; AED; antiepileptic drug; CBZ; carbamazepine; CLB; clobazam; CZP; clonazepam; ESL; eslicarbazepine acetate; GBP; gabapentin; ILAE; International League Against Epilepsy; LCM; lacosamide; LEV; levetiracetam; LTG; Lamotrigine; Na; sodium; OXC; oxcarbazepine;
Keywords: پرامانپل; Perampanel; Efficacy; Adverse effects; Intellectual disability; Behavior;
Keywords: پرامانپل; AED; anti-epileptic drug; CMZ; carbamazepine; GTK; generalized tonic-clonic seizure; EEG; electroencephalography; IQ; intelligence quotient; LEV; levetiracetam; LTG; lamotrigine; MRI; magnetic resonance imaging; PER; perampanel; PET; positron emission tom
Keywords: پرامانپل; AED; antiepileptic drug; IQR; interquartile range; PER; perampanel; SD; standard deviation; SUDEP; sudden unexplained death in epilepsy; Cox regression analysis; Antiepileptic drugs; Drug resistant; Treatment;
Keywords: پرامانپل; Drug-resistant epilepsy; Cognitive impairment; Perampanel; Psychiatric adverse effects;
Keywords: پرامانپل; Perampanel; Levetiracetam; Topiramate; Epilepsy; Aggression; Hostility;
Keywords: پرامانپل; Epilepsy; Refractory epilepsy; Perampanel; Children;
Keywords: پرامانپل; Lafora disease; Progressive myoclonus epilepsy; Perampanel; Antiepileptic;
Keywords: پرامانپل; Perampanel; Antiepileptic drugs; Efficacy; Focal epilepsy; Side effects;
Keywords: پرامانپل; Perampanel; Efficacy; Safety; Adverse events; Postmarketing;
Keywords: پرامانپل; Epilepsy; Perampanel; Antiepileptic drugs; Learning disability; Psychiatric comorbidity;
Keywords: پرامانپل; Hypoxic myoclonic status; Perampanel
Keywords: پرامانپل; Nonconvulsive status epilepticus; Perampanel; Criteria of efficacy;
Keywords: پرامانپل; AE; adverse event; AED; antiepileptic drug; BMI; body mass index; CP; complex partial seizure; DB; double blind; EMA; European Medicines Agency; FDA; US Food and Drug Administration; ITT; intent to treat; MTD; maximum tolerated dose; PBO; placebo; PER; pe
Keywords: پرامانپل; Refractory status epilepticus; Noncompetitive AMPA receptor antagonist; Glutamate; Perampanel; Seizure;
Keywords: پرامانپل; BID, twice daily; CBZ, carbamazepine; EIAED, enzyme-inducing antiepileptic drug; PER, perampanel; POSs, partial-onset seizures; QD, once dailyDosing; Antiepileptic drugs; Perampanel; Pharmacokinetics; Adherence
Keywords: پرامانپل; Epilepsy; Perampanel; Antiepileptic drug; Responder rate; Tolerability; Efficacy
Perampanel in the treatment of status epilepticus: A systematic review of the literature
Keywords: پرامانپل; Efficacy; Perampanel; Seizures; Status epilepticus; Tolerability;
Cost-effectiveness of perampanel for the treatment of primary generalized tonic-clonic seizures (PGTCS) in epilepsy: A Spanish perspective
Keywords: پرامانپل; Perampanel; Fycompa; Cost-effectiveness; Spain;
Pharmacokinetics and brain uptake study of novel AMPA receptor antagonist perampanel in SD rats using a validated UHPLC-QTOF-MS method
Keywords: پرامانپل; Perampanel; Protein precipitation; Extracted ion chromatography; Brain to plasma ratio; UHPLC-QTOF-MS;
Clinical outcomes of perampanel vs. lacosamide in cohorts of consecutive patients with severely refractory epilepsies - A monocentric retrospective analysis of systematically collected data from the German Kork Epilepsy Center
Keywords: پرامانپل; Perampanel; Lacosamide; Epilepsy; Focal seizures; Clinical practice; Retrospective analysis;
Perampanel in the general population and in people with intellectual disability: Differing responses
Keywords: پرامانپل; Epilepsy; Intellectual disability; UK Ep-ID research Register; Perampanel;
Neuropathic pain attenuating effects of perampanel in an experimental model of chronic constriction injury in rats
Keywords: پرامانپل; Chronic constriction injury; Perampanel; Neuropathic pain; Naloxone;
Preliminary Asian experience of using perampanel in clinical practice
Keywords: پرامانپل; Perampanel; Adverse event; Efficacy; Safety;
Radiosynthesis and preliminary PET evaluation of 18F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors
Keywords: پرامانپل; mGluRs; metabotropic glutamate receptors; iGluRs; ionotropic glutamate receptors; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PET; positron emission tomography; CNS; central nervous system; TEA[18F]; [18F]tetra
Efficacy and tolerability of adjunct perampanel based on number of antiepileptic drugs at baseline and baseline predictors of efficacy: A phase III post-hoc analysis
Keywords: پرامانپل; Antiepileptic drugs; Perampanel; Concomitant; Enzyme-inducing; Efficacy; AED; antiepileptic drug; ANCOVA; analysis of covariance; BMI; body mass index; CI; confidence interval; CNS; central nervous system; SAE; serious adverse event; TEAE; treatment-emerg
Effectiveness and tolerability of perampanel in children and adolescents with refractory epilepsies-An Italian observational multicenter study
Keywords: پرامانپل; Perampanel; Refractory epilepsy; Children; Adolescents; Treatment outcome; Antiepileptic drug;
Pharmacokinetics, exposure-cognition, and exposure-efficacy relationships of perampanel in adolescents with inadequately controlled partial-onset seizures
Keywords: پرامانپل; AED; antiepileptic drug; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; Cav,ss; average steady-state plasma concentration at; CDR; Cognitive Drug Research system; CNS; central nervous system; CL/F; apparent clearance; CYP; cytochrome P450; IIV
ReviewEfficacy and tolerability of brivaracetam compared to lacosamide, eslicarbazepine acetate, and perampanel as adjunctive treatments in uncontrolled focal epilepsy: Results of an indirect comparison meta-analysis of RCTs
Keywords: پرامانپل; Brivaracetam; Eslicarbazepine acetate; Focal epilepsy; Lacosamide; Meta-analysis; Perampanel;
Safety, efficacy and outcome-related factors of perampanel over 12 months in a real-world setting: The FYDATA study
Keywords: پرامانپل; Epilepsy; Perampanel; Real-world; Antiepileptic drug;
Inhibition of calcium-permeable and calcium-impermeable AMPA receptors by perampanel in rat brain neurons
Keywords: پرامانپل; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CP-AMPARs; calcium-permeable AMPA receptors; CI-AMPARs; calcium-impermeable AMPA receptors; AMPA receptors; Anticonvulsants; Perampanel; Inhibition; Mechanisms; Patch clamp;
The effects of AMPA blockade on the spectral profile of human early visual cortex recordings studied with non-invasive MEG
Keywords: پرامانپل; MEG; Visual cortex; Gamma oscillations; AMPA receptors; Perampanel;
Les nouveaux médicaments en neurologie
Keywords: پرامانپل; antiépileptique; neurologie; pérampanel; sclérose en plaques; tafamidis; tériflunomide; transthyrétineantiepileptic; multiple sclerosis; neurology; perampanel; tafamidis; teriflunomide; transthyretin
Efficacy and safety of perampanel in the subgroup of elderly patients included in the phase III epilepsy clinical trials
Keywords: پرامانپل; Adverse effects; Antiepileptic drugs; Efficacy; Elderly; Perampanel; AE; adverse event; AED; antiepileptic drug; LOCF; last observation carried forward; MedDRA; Medical Dictionary for Regulatory Activities; PER; perampanel; PK; pharmacokinetic; SAE; serio
High-performance liquid chromatography-tandem mass spectrometry method for the determination of perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist in human plasma
Keywords: پرامانپل; AED; anti-epileptic drugs; AMPA; α-amin-3-hydroxyl-5methyl-4isoxazolepropionic acid; AUC; area under the plasma concentration-time curve; AUC0-inf; AUC extrapolated to infinity; AUC0-last; AUC to the last time points; AUMC; area under the first mom
Analysis of pooled phase III trials of adjunctive perampanel for epilepsy: Impact of mechanism of action and pharmacokinetics on clinical outcomes
Keywords: پرامانپل; AE; adverse event; AED; antiepileptic drug; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; CYP; cytochrome P450; EIAED; enzyme-inducing antiepileptic drug; SCB; sodium channel blocker; TEAE; treatment-emergent adverse event; Perampanel; Par
Perampanel in the treatment of partial seizures: Time to onset and duration of most common adverse events from pooled Phase III and extension studies
Keywords: پرامانپل; AED; antiepileptic drug; DB; double blind; MedDRA; Medical Dictionary for Regulatory Activities; MTD; maximum tolerated dose; OLE; open-label extension; PBO; placebo; PER; perampanel; TEAE; treatment-emergent adverse event; Antiepileptic drugs; Epilepsy;
The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy
Keywords: پرامانپل; Glutamate receptors; Epileptogenesis; Perampanel; Ketamine; NMDA receptors; AED; antiepileptic drug; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ED50; effective dose for 50% seizure suppression; EEG; electroencephalogram; HPD; hippocampal
Absence of Liver Toxicity in Perampanel-Treated Subjects: Pooled results from partial seizure phase III perampanel clinical studies
Keywords: پرامانپل; Antiepileptic drugs; Epilepsy; Hepatic; Liver; Partial seizures; Perampanel; AE; adverse event; AED; antiepileptic drug; ALT; alanine aminotransferase; AST; aspartate aminotransferase; GGT; gamma-glutamyl transferase; NCI-CTC; National Cancer Institute Co
Efficacy and safety of perampanel in adolescent patients with drug-resistant partial seizures in three double-blind, placebo-controlled, phase III randomized clinical studies and a combined extension study
Keywords: پرامانپل; Adolescent; Antiepileptic drugs; Epilepsy; Perampanel; Post hoc analysis; AE; adverse event; AED; antiepileptic drug; ANCOVA; analysis of covariance; BMI; body mass index; CP; complex partial seizure; ECG; electrocardiogram; EU; European Union; ITT; inten
Clinical experience with perampanel: Focus on psychiatric adverse effects
Keywords: پرامانپل; Perampanel; Suicidality; Epilepsy;
Neuropharmacology and analgesiaReversal of novelty-induced hippocampal c-Fos expression in GluA1 subunit-deficient mice by chronic treatment targeting glutamatergic transmission
Keywords: پرامانپل; Lithium carbonate (PubChem CID: 11125); Sodium valproate (PubChem CID: 16760703); Topiramate (PubChem CID: 5284627); Lamotrigine (PubChem CID: 3878); Perampanel (PubChem CID: 9924495); Hyperactivity; Anti-mania drugs; Perampanel; GluA1 subunit knockout; M
One step synthesis of 1,5-diaryl pyridin-2(1H)-ones from 2-aryl vinamidinium salts and N-aryl cyanoacetamides
Keywords: پرامانپل; N-Aryl pyridin-2(1H)-one; Perampanel; Copper-catalyzed; Chan-Lam coupling; Ullmann reaction; Vinamidinium salt;