Pore formation: An ancient yet complex form of attack
Keywords: پرفورین; Pore-forming toxin; Perforin; Cholesterol-dependent cytolysin; Aerolysin; Actinoporin
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Generation and maintenance of Listeria-specific CD8+ T cell responses in perforin-deficient mice chronically infected with LCMV
Keywords: پرفورین; Lymphocytic choriomeningitis virus; Listeria monocytogenes; CD8 T cells; Immunity; Immunodeficiency; Perforin; Memory
Synergistic effects of IL-2, IL-12 and IL-18 on cytolytic activity, perforin expression and IFN-γ production of porcine natural killer cells
Keywords: پرفورین; NK cells; Cytokine stimulation; Swine; Perforin
Rodzinna limfohistiocytoza - seria niefortunnych zdarzeÅ
Keywords: پرفورین; rodzinna limfohistiocytoza; zespóÅ hemofagocytarny; gorÄ
czka o nieustalonej etiologii; perforyna; hepatosplenomegalia; przeszczepienie krwiotwórczych komórek macierzystych; familial haemophagocytic lymphohistiocytosis (FHL); haemophagocytic syndrome;
Healthy lifestyles are associated with higher levels of perforin, granulysin and granzymes A/B-expressing cells in peripheral blood lymphocytes
Keywords: پرفورین; Granulysin; Granzyme; Lifestyle; NK cell; Perforin; T cell
Protection against polyoma virus-induced tumors is perforin-independent
Keywords: پرفورین; Polyoma virus; CD8 T cell; Perforin; Fas; TNF; Tumor; Pathogenesis
Analysis of perforin expression in peripheral blood and lesions in severe and mild psoriasis
Keywords: پرفورین; Apoptosis; Cytotoxic T lymphocytes; Natural killer cells; Perforin; Psoriasis
Granzyme B induction signalling pathway in acute myeloid leukemia cell lines stimulated by Tumor Necrosis Factor alpha and Fas Ligand
Keywords: پرفورین; TNF; Tumor Necrosis Factor; FasL; Fas Ligand; AML; acute myeloid leukemia; GrB; granzyme B; PFN; perforin; TNFR; TNF receptor; ROS; Radical oxygen species; MAPK; Mitogen-activated-protein-kinase; ASK1; Apoptosis-signal-regulating-kinase 1; Trx; Thioredoxi
CSF enrichment of highly differentiated CD8+ T cells in early multiple sclerosis
Keywords: پرفورین; Multiple sclerosis; CD8+ T cells; T cell phenotyping; Cerebrospinal fluid; Perforin; CCR7; CD45RA; Chemokines; Cytokines
Secretory lysosomes and their cargo in T and NK cells
Keywords: پرفورین; Cytotoxic T cells; Natural killer cells; Secretory lysosomes; Vesicles; Granulysin; Granzyme; Perforin; FasL; Immunological synapse; Lysosomal transport
Early pregnancy decidual lymphocytes beside perforin use Fas ligand (FasL) mediated cytotoxicity
Keywords: پرفورین; Cytotoxicity; Decidual lymphocytes; Fas ligand; Perforin; Th1 cytokines
IFNα2b stimulated release of IFNγ differentially regulates T cell and NK cell mediated tumor cell cytotoxicity
Keywords: پرفورین; Cytotoxicity; Head and neck squamous cell carcinoma; IFNα2b; IFNγ; Perforin
In vitro atrazine-exposure inhibits human natural killer cell lytic granule release
Keywords: پرفورین; Atrazine; Natural killer cells; Perforin
In vivo evoked specific cell mediated cytotoxicity in carp (Cyprinus carpio L.) uses mainly a perforin/granzyme-like pathway
Keywords: پرفورین; Carp; Cell mediated cytotoxicity; Perforin; Granzyme
Natural Killer-like T-Cell Lymphoma in a Calf
Keywords: پرفورین; cattle; CD57; lymphoma; NK-like T-cell lymphoma; perforin; tumour
Perforin Down-Regulation and Adhesion Molecules Activation in Pulmonary Sarcoidosis : An Induced Sputum and BAL Study
Keywords: پرفورین; BAL fluid; CD62; CD71; induced sputum; pathophysiology; perforin; sarcoidosis; Tc1/Tc2 profileACE, angiotensin-converting enzyme; BALF, BAL fluid; IFN, interferon; IL, interleukin; IPF, idiopathic pulmonary fibrosis; PMA, phorbol 12-myristate 13-acetate;
CD8+HLA-DR+ T lymphocytes are increased in common variable immunodeficiency patients with impaired memory B-cell differentiation
Keywords: پرفورین; Common variable immunodeficiency; HLA-DR; Perforin; Granzyme B; Cytotoxic lymphocytes
Characterization of a cytotoxic CD57+ T cell subset from patients with pulmonary tuberculosis
Keywords: پرفورین; Mycobacterium tuberculosis immune response; Cytotoxicity; CD8+CD57+ T cells; IFN-γ; TNF-α; Granzyme-A; Perforin
Noninvasive Diagnosis of Cellular and Antibody-Mediated Rejection by Perforin and Granzyme B in Renal Allografts
Keywords: پرفورین; Cellular rejection; Antibody-mediated rejection; Perforin; Granzyme B; Novel statistical analysis
Modulation of cytokines production, granzyme B and perforin in murine CIK cells by Ganoderma lucidum polysaccharides
Keywords: پرفورین; Polysaccharides; Cytokine; Perforin; Granzyme B; Antitumour activity; Immunomodulatory
NKG2D and cytotoxic effector function in tumor immune surveillance
Keywords: پرفورین; Natural killer; Cytotoxicity; NKG2D; Perforin; Cancer
CD8 T cell effector maturation in HIV-1-infected children
Keywords: پرفورین; Human; T cells; CD8; CD4; HIV; Viral infections; AIDS; Pediatric; Perforin; Granzyme
Nonspecific cytotoxic cells of teleosts are armed with multiple granzymes and other components of the granule exocytosis pathway
Keywords: پرفورین; Granzymes; Perforin; Granulysin; Serglycin; Thiobenzyl ester substrates; Nonspecific cytotoxic cells
Perforin mediated apoptosis of cerebral microvascular endothelial cells during experimental cerebral malaria
Keywords: پرفورین; T lymphocytes; Cerebral malaria; Endothelial cells; Neuroimmunology; Apoptosis; Perforin
Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes
Keywords: پرفورین; Perforin; Granzyme B; Cytotoxic T lymphocytes;
Hyperthermia suppresses the cytotoxicity of NK cells via down-regulation of perforin/granzyme B expression
Keywords: پرفورین; Whole body hyperthermia; NK cells; Perforin; Granzyme B; FasL/TRAIL; Infrared box; Rag-2 knockout mouse;
Physiopathologie de la maladie de Still de l'adulte
Keywords: پرفورین; Maladie de Still de l'adulte; Activation macrophagique; Interleukine 18; Cytokine; Perforine; Adult-onset Still's disease; Macrophage activation; Interleukin 18; Cytokin; Perforin;
Dibutyltin exposure decreases granzyme B and perforin in human natural killer cells
Keywords: پرفورین; Dibutyltin; Immunotoxicity; Organotin; Granzyme B; Perforin;
Dimethyl 2,2-dichlorovinyl phosphate (DDVP) markedly decreases the expression of perforin, granzyme A and granulysin in human NK-92CI cell line
Keywords: پرفورین; Dimethyl 2,2-dichlorovinyl phosphate (DDVP, dichlorvos); Flow cytometry; Granzyme A; Granulysin; Immunofluorescence microscope; NK; Perforin;
Combinational IL-2/IL-15 induction does not further enhance IL-15-induced lymphokine-activated killer cell cytotoxicity against human leukemia/lymphoma cells
Keywords: پرفورین; IL-2 and IL-15 combination; Cell-mediated cytotoxicity; NK/LAK activity; Flow cytometric cell-mediated cytotoxicity assay; Leukemia/lymphoma cells; Cytotoxic NK-T cell; Perforin; Granzyme B; Tumor necrosis factor-α; Interferon-γ;
Perforin improves the morphogenesis of mouse placenta disturbed by IL-2 treatment
Keywords: پرفورین; Interleukin-2; Perforin; Trophoblast glycogen cell; Uterine NK cell; gzmB; granzyme B; IL-2Rβ; interleukin-2 receptor β-chain; PKO; perforin knockout; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling; uNK cell; uterine natura
Effector, memory and naïve CD8+ T cells in peripheral blood and pleural effusion from lung adenocarcinoma patients
Keywords: پرفورین; CD8+ T subsets; Lung adenocarcinoma; Pleural effusion; Peripheral blood; Fas; Perforin; Flow cytometry;
Cytokines and cytotoxic pathways in engraftment resistance to purified allogeneic hematopoietic stem cells
Keywords: پرفورین; Cytokines; Perforin; Fas ligand; Stem cell transplantation; Engraftment;
Detection of human perforin by ELISpot and ELISA: Ex vivo identification of virus-specific cells
Keywords: پرفورین; CMV; cytomegalovirus; CTL; cytotoxic T lymphocyte; EBV; Epstein-Barr virus; ELISA; enzyme-linked immunosorbent assay; ELISpot; enzyme-linked immunospot assay; FCS; fetal calf serum; Gr; granzyme; IHC; immunohistochemistry; mAb; monoclonal antibody; NK cel