Keywords: AA; arachidonic acid; AKR; aldo-keto reductase; AOS; allene oxide synthase; CX; carbon numbers; COX; cyclooxygenase; cPGES; cytosolic PGE synthase; cPLA2; cytosolic phospholipase A2; CYP; cytochrome P450; DGLA; dihomo-γ-linolenic acid; DP; prostaglandin
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Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression
Keywords: ANOVA; analysis of variance; AA; arachidonic acid; BUN; blood urea nitrogen; COX; cyclooxygenase; EAE; experimental autoimmune encephalomyelitis; IRAK1; interleukin-1 receptor-associated kinase 1; LPS; lipopolysaccharide; LPS-EB; LPS from E. coli O111: B4
Prostaglandin H synthase kinetics in the two-phase aqueous-micellar system
Keywords: PGHS; prostaglandin H synthase; AA; arachidonic acid; COX reaction; cyclooxygenase reaction; POX reaction; peroxidase reaction; KM; Michaelis constant in the Michaelis-Menten equation; Vm; the maximum enzymatic reaction rate in the Michaelis-Menten equati
Reinterpreting the best biomarker of oxidative stress: The 8-iso-prostaglandin F2α/prostaglandin F2α ratio shows complex origins of lipid peroxidation biomarkers in animal models
Keywords: 8-iso-PGF2α; 8-iso-prostaglandin F2α; PGF2α; prostaglandin F2α; PGHS; prostaglandin-endoperoxide synthases, cyclooxygenases; CLP; chemical lipid peroxidation; 8-iso-PGF2α/PGF2α ratio; F2-isoprostanes; Oxidative stress; Inflammation; Biomarkers; Lipi
Synthesis of new 4-phenylpyrimidine-2(1H)-thiones and their potency to inhibit COX-1 and COX-2
Keywords: 4-Phenylpyrimidine-2(1H)-thiones; Inhibition of cyclooxygenases; BCS; biopharmaceutics classification system; CH3OH; methanol; COX; cyclooxy-genase; DMSO; dimethylsulfoxide; EDTA; ethylenediaminetetraacetic acid; EIA; enzyme immuno assay; ELISA; enzyme li
Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation
Keywords: AA; arachidonic acid; ApAP; acetaminophen; CL; cardiolipin; cyt c; cytochrome c; ETC; electron transport chain; HPLC; high performance liquid chromatography; L4CL; tetralinoleoyl cardiolipin; LC-MS; liquid chromatography-mass spectrometry; M4CL; Tetra
Targeted exchange of an expression cassette encoding cyclooxygenase-2 at the Ptgs1 locus
Keywords: COX; cyclooxygenase; PGHS; prostaglandin H synthase; WT; wild type; HM; homozygous knock-in; HT; heterozygous knock-in; Neo; neomycin resistance gene; LPS; lipopolysaccharide; KIF; kifunensine; S-FBP; (S)-flurbiprofen; PMEFs; primary mouse embryo fibrobla
Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages
Keywords: AA; arachidonic acid; ChIP; chromatin immunoprecipitation; COX; cyclooxygenase; Egr-1; early growth response 1; LUC; luciferase; PG; prostaglandin; mPGES-1; microsomal Prostaglandin E synthase 1; cPGES; cytosolic Prostaglandin E synthase; PGHS; Prostaglan
Acetylation of prostaglandin H2 synthases by aspirin is inhibited by redox cycling of the peroxidase
Keywords: PGHS; prostaglandin H2 synthase; PG; prostaglandin; 12-HPETE; 12-hydroperoxyeicosatetraenoic acid; 12-HETE; 12-hydroxyeicosatetraenoic acid; PPHP; 5-phenyl-4-pentenyl hydroperoxide; PPA; 5-phenyl-4-pentenyl alcohol; DMEM; Dulbecco's modified Eagle's mediu
Inherited bleeding disorder due to familial type 2 platelet cyclo-oxygenase deficiency
Keywords: AA; acid arachidonic; ACD; acid-citrate-dextrose; ADP; adenosine 5â²-diphosphate; COX; cyclo-oxygenase; ETP; endogenous thrombin potential; 12-HETE; 12-Hydroxy-5,8,11,14-eicosatetraenoic acid; 12-HHTrE; 12-Hydroxy-5,8,10-heptadecatrienoic acid; PG; pro
Effects of Bovine Somatotropin on Uterine Genes Related to the Prostaglandin Cascade in Lactating Dairy Cows*
Keywords: uterus; gene; bovine somatotropin; receptor; ERα; estrogen receptor alpha; PGHS; prostaglandin endoperoxide synthase; PPAR; peroxisome proliferator-activated receptor; TBS; Tris-buffered saline;
Acetaminophen decreases intracellular glutathione levels and modulates cytokine production in human alveolar macrophages and type II pneumocytes in vitro
Keywords: APAP; acetaminophen; CYP; cytochrome P450; DDTC; diethyldithiocarbamic acid; DMEM; Dulbecco's modified Eagle's medium; DNase; deoxyribonuclease; FBS; fetal bovine serum; GSH; reduced glutathione; PGHS; prostaglandin H synthetase; IL-6; interleukin 6; IL-8
ESR spin trapping of a carbon-centered free radical from agonist-stimulated human platelets
Keywords: AA; arachidonic acid; cPLA2; cytosolic phospholipase A2; AACOCF3; 5,8,11,14-eicosatetraenoic trifluoromethyl ketone; DMPO; 5,5-dimethyl-1 pyrroline N-oxide; ESR; electron spin resonance; HPETE; hydroperoxyeicosatetraenoic acids; PBN; α-phenyl N-tert.-but
On the mechanism of biosynthesis of 19-hydroxyprostaglandins of human seminal fluid and expression of cyclooxygenase-2, PGH 19-hydroxylase (CYP4F8) and microsomal PGE synthase-1 in seminal vesicles and vas deferens
Keywords: Carbaprostacyclin; Co-localization; Hydroxyprostaglandin; Immunohistochemistry; Real-time PCR; Liquid chromatography-mass spectrometry; COX; cyclooxygenase; CYP; cytochrome P450; ER; endoplasmic reticulum; 6,9α-Methylene-PGI2; carbaprostacyclin; 9α,11α
Reaction of haem containing proteins and enzymes with hydroperoxides: The radical view
Keywords: AA; arachidonic acid; apo; prefix for the haem proteins that are forced to lose their haem group; BLC; bovine liver catalase; CcO; cytochrome c oxidase; CcP; cytochrome c peroxidase; CuOOH; cumene hydroperoxide PhC(CH3)2OOH; Cyt c; cytochrome c; DBNBS; 3,