The evaluation of potent antitumor activities of shikonin coumarin-carboxylic acid, PMMB232 through HIF-1α-mediated apoptosis
Keywords: phenylmethanesulfonyl fluoride; HIF-1α; hypoxia-inducible factor alpha 1; DMAP; 4 dimethyamino- pyridine; DCC; N, N' dicyclohexylcarbodiimide; DMEM; Dulbecco's modified Eagle's medium; MTT; 3-(4 5-dimethyl-2-thiazolyl)-2 5-diphenyl-2-H-tetrazolium bromide; IC50; Half of maximal i