دانلود مقالات ISI درباره Phosphatidylinositol 3-Kinases + ترجمه فارسی

آسکوربات فارماکولوژیک باعث کاهش مرگ سلول نوروبلاستوما توسط پراکسید هیدروژن می شود و باعث کاهش میزان گلیکولیس سلول سرطانی می شود.

Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis

Keywords: 3-MA; 3-methyladenine; Asc; ascorbate; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BRAF; murine sarcoma viral oncogene homolog B; Cat; catalase; Chk2; checkpoint kinase 2; CQ; chloroquine; Cys-SO3H; cysteine S-sulfate; DHA; dehydroasc

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

شناسایی جهش های قابل اجرا در مزوتلیوما پلورال مزمن

Identification of actionable mutations in malignant pleural mesothelioma

Keywords: Gene amplification; Gene alteration; Mesothelioma; Mutation; Phosphatidylinositol 3-kinases; VHL tumor suppressor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

حفاظت از عصب هورمون های استروئیدی گنادال در آسیب مغزی حاد نیاز به همکاری با آستروگلیا و میکروگلاییا

Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microglia

Keywords: AD; Alzheimer's disease; AQP; aquaporin; ATP; adenosine triphosphate; BBB; blood-brain barrier; BSA; bovine serum albumin; CaMK; Ca2+/calmodulin-dependent protein kinases; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; ER;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway

Keywords: ADSCs; adipose tissue-derived stem cells; ADSC-Exos; ADSC-derived exosomes; bFGF; basic fibroblast growth factor; CM; conditioned medium; Col 1; type I collagen; Col 3; type III collagen; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

AKT activity is elevated in aggressive thyroid neoplasms where it promotes proliferation and invasion

Keywords: Thyroid neoplasms; Phosphatidylinositol 3-kinases; Thyroid cancer, papillary; Thyroid carcinoma, anaplastic; Neoplastic stem cells; MTOR protein, human.;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells

Keywords: Signal transduction; Janus kinase; STAT; Phosphatidylinositol 3-Kinases; Proto-oncogene proteins c-akt; Mammary gland development; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

p55PIK regulates alpha-fetoprotein expression through the NF-κB signaling pathway

Keywords: Alpha-fetoproteins; NF-κB; Phosphatidylinositol 3-kinases; Hepatocellular carcinoma; Promoter regions; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells

Keywords: Polyalthia longifolia; 16-Hydroxycleroda-3,13-dien-15,16-olide; Renal cell carcinoma; Apoptosis; AO/EB; acridine orange and ethidium bromide; Bcl-2; B cell lymphoma 2; ccRCC; clear cell renal cell carcinoma; CD; 16-hydroxycleroda-3,13-dien-15,16-olide; ER

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Cancer TARGETases: DSB repair as a pharmacological target

Keywords: DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel

دانلود رایگان متن کامل مقاله ISI 110 صفحه سال انتشار : 2016 سفارش ترجمه

Exemestane metabolites suppress growth of estrogen receptor-positive breast cancer cells by inducing apoptosis and autophagy: A comparative study with Exemestane

Keywords: Estrogen receptor-positive breast cancer; Aromatase inhibitors; Exemestane metabolites; Apoptosis; Autophagy; Acquired-resistance; AIs; aromatase inhibitors; AO; acridine orange; AVOs; acid vesicular organelles; CCCP; carbonyl cyanide m-chlorophenylhydraz

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Differential regulation of chemotaxis: Role of Gβγ in chemokine receptor-induced cell migration

Keywords: CHO; Chinese hamster ovary; CCL3; Chemokine ligand 3; CCR5; Chemokine receptor 5; DMEM; Dulbecco's modified Eagle's medium; EDTA; Ethylenediaminetetraacetic acid; ERK; Extracellular signal-regulated kinases; FCS; Foetal calf serum; GPCR; G protein coupled

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Plasma membrane Pdia3 and VDR interact to elicit rapid responses to 1α,25(OH)2D3

Keywords: 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; VDR; vitamin D receptor; Pdia3; protein disulfide isomerase family A, member 3; PLA2; phospholipase A2; PLAA; PLA2 activating protein; PGE2; prostaglandin E2; PI3K; phosphatidylinositol 3-kinases; Alpl; alkaline

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases

Keywords: PI3Ks; phosphatidylinositol 3-kinases; PIP3; phosphatidylinositol 3,4,5-triphosphate; QPLD; Quantum-Polarized Ligand Docking; PI3K; Docking; Pharmacophore modeling; Apoptosis; LY294002; GSK2126458;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Ascorbate stimulates endothelial nitric oxide synthase enzyme activity by rapid modulation of its phosphorylation status

Keywords: AMPK; AMP-activated protein kinase; BH4; tetrahydrobiopterin; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric oxide synthase; FBS; fetal bovine serum; HA-tag; hemagglutinin tag; Hepes; 4-(2-hydroxyethyl)-1-pipe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms

Keywords: IpLITRs; Ictalurus punctatus leukocyte immune-type receptors; SH2; Src homology 2; SHP; Src homology 2 domain-containing cytoplasmic phosphatase; Csk; C-terminal Src kinase; ITAM; immune receptor tyrosine-based activation motif; SFK; Src-family protein ty

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Thyroid hormone differentially modulates Warburg phenotype in breast cancer cells

Keywords: T3; triiodothyronine; T4; thyroxine; 2NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diaxol-4-yl)amino]-2-deoxyglucose; DCFDA; 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester; TMRM; tetramethyl rhodamine methyl ester; ROS; reactive

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/Phosphatidylinositol 3-kinase signaling pathway

Keywords: collagen VI; neuroprotection; UV; Akt/PI3K; NeurotoxQ; DAPI; 4′-6-diamidino-2-phenylindole; ECM; extracellular matrix; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; JNK; jun N-terminal kinase; MAP-2; microtubule

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Wortmannin delays transfer of human rhinovirus serotype 2 to late endocytic compartments

Keywords: Picornaviruses; Human rhinoviruses; Minor receptor group; HeLa cells; Wortmannin; Phosphatidylinositol 3-kinases; Endocytosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه