کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10971725 1106516 2012 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms
چکیده انگلیسی
► IpLITRs encoding cytoplasmic ITIMs are potent inhibitors of lymphocyte cytotoxicity. ► IpLITR-mediated inhibition is mediated by a SHP-1-dependent and -independent mechanism. ► The SHP-1-independent inhibitory mechanism is also ITIM-independent and may involve binding of the C-terminal Src kinase. ► Teleosts contain an array of inhibitory signaling mediators and their intracellular targets similar to those found in mammals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental & Comparative Immunology - Volume 37, Issue 1, May 2012, Pages 151-163
نویسندگان
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