Keywords: MNCs; multinucleated cells; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear factor-κB ligand; M-CSF; macrophage colony stimulating factor; OPG; osteoprotegerin; c-fms; colony-stimulating factor-1 receptor; ERK; extracellul
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Src family kinase tyrosine phosphorylates Toll-like receptor 4 to dissociate MyD88 and Mal/Tirap, suppressing LPS-induced inflammatory responses
Keywords: BMMCs; bone marrow-derived mast cells; Csk; C-terminal Src kinase; IRF; IFN-regulated factor; Mal; myeloid differentiation factor 88 (MyD88)-adapter-like; SFK; Src-family kinase; TIR domain; Toll/IL-1R (TIR) domain; Tirap; toll-interleukin 1 receptor (TIR
Interaction of DJ-1 with Lyn is essential for IgE-mediated stimulation of human mast cells
Keywords: Human mast cells; IgE receptor; Lyn activation; DJ-1; signaling; reactive oxygen species; spleen tyrosine kinase; Csk; C-terminal Src kinase; ERK; Extracellular signal-regulated kinase; HuMC; CD34+-derived human mast cell; JNK; c-Jun N-terminal kinase; LA
Imaging flow cytometry and GST pulldown assays provide new insights into channel catfish leukocyte immune-type receptor-mediated phagocytic pathways
Keywords: Phagocytosis; Immunoregulatory receptors; Intracellular signaling; Actin polymerization machinery; Imaging flow cytometry; Innate immunity; Channel catfish; Leukocyte immune-type receptors; IpLITR; channel catfish leukocyte immune-type receptor; CYT; cyto
Src-family tyrosine kinases and the Ca2Â + signal
Keywords: 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr
Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL
Keywords: ESDN; endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; discoidin CUB and LCCL domain containing 2; CUB; complement C1r/C1s Uegf Bmp1; CrkL; CrkCT10 regulator of kinase Crk-Like; SFK; Src family tyrosine kinase; Cas; Crk-associat
Cutl1: A potential target for cancer therapy
Keywords: CDP; CCAAT displacement protein; HCC; human hepatocellular carcinoma; LETFs; liver-enriched transcription factors; HNF; hepatocyte nuclear factor; Shh; Sonic hedgehog; C/EBPα; CCAAT/enhancer-binding protein; MMTV; mouse mammary tumor virus; PCAF; p300/CR
Quantitative profiling of tyrosine phosphorylation revealed changes in the activity of the T cell receptor signaling pathway upon cisplatin-induced apoptosis
Keywords: 7-AAD; 7-amino-actinomycin D; Atf2; activating transcription factor 2; Csk; C-terminal Src kinase; Erk; extracellular-signal-regulated kinase; FCB; fluorescent cell barcoding; FSC; forward scatter; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IL-2; in
CB1 cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells
Keywords: 2-AG; 2-arachidonoylglycerol; BSA; bovine serum albumin; CB1; CB1 cannabinoid receptor; Csk; C-terminal Src kinase; DAGL; diacylglycerol lipase; DTT; dithiothreitol; ECM; extracellular matrix; ERK1/2; extracellular signal-regulated kinases 1 and 2; EGFR;
Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells
Keywords: SFKs; Src family tyrosine kinases; EGF-R; epidermal growth factor receptor; PDGF-R; platelet-derived growth factor receptor; IGF-1R; insulin-like growth factor-1 receptor; VEGF-R; vascular endothelial growth factor receptor; FGF-R; fibroblast growth facto
Modulation of FcεRI-dependent mast cell response by OX40L via Fyn, PI3K, and RhoA
Keywords: OX40L; Fyn; PI3K; mast cell; degranulation; anaphylaxis; BM; Bone marrow; Cbp; C-terminal Src kinase-binding protein; Csk; C-terminal Src kinase; DNP; Di-nitro-phenyl; MC; Mast cell; MTOC; Microtubule organizing center; NIH; National Institutes of Healt
Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms
Keywords: IpLITRs; Ictalurus punctatus leukocyte immune-type receptors; SH2; Src homology 2; SHP; Src homology 2 domain-containing cytoplasmic phosphatase; Csk; C-terminal Src kinase; ITAM; immune receptor tyrosine-based activation motif; SFK; Src-family protein ty
Cyclic AMP-mediated immune regulation - Overview of mechanisms of action in T cells
Keywords: AC; Adenylyl cyclase; AKAP; A-kinase anchoring protein; AKAP-KL; AKAP-kidney lung; AKB; A-kinase binding domain; AP-1; Activator protein 1; ATF; Activation transcription factor; C; Catalytic (subunit of PKA); CBP; CREB-binding protein; CNG; Cyclic nucleot
Nonreceptor Tyrosine Kinases in Prostate
Keywords: Nonreceptor tyrosine kinase; prostate cancer; Src; FAK; ETK; Abl; v-Abl Abelson murine leukemia viral oncogene homolog; At; androgenindependent; Aid; v-akt murine thymoma viral oncogene homolog 1; AR; androgen receptor; ARG; Abelson-related gene; Bcr; bre
Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases
Keywords: SFK; Src-family protein tyrosine kinases; CSK; C-terminal Src kinase; CHK; CSK-homologous kinase; SH2 and SH3 domains; Src-homology 2 and Src-homology 3 domains; YT; C-terminal tail regulatory tyrosine of SFKs; YA; autophosphorylated tyrosine in the activ
Protein kinase structure and function analysis with chemical tools
Keywords: AANAT; serotonin N-acetyltransferase or arylalkylamine N-acetyltransferase; aPP; avian pancreatic polypeptide; CaMKII; Ca2+/calmodulin kinase II; CAT; chloramphenicol acetyltransferase; CHO; Chinese hamster ovary; Csk; C-terminal Src kinase; Fmoc; fluoren
CSK negatively regulates nerve growth factor induced neural differentiation and augments AKT kinase activity
Keywords: SFKs; Src family kinases; NGF; nerve growth factor; CSK; C-terminal Src kinase; PBD; p21 binding domain; SH2; SRC homology-2 domain; WT-CSK; wild type CSK; KD-CSK; kinase-dead CSK; PC12 cells; CSK; SRC; FYN; YES; NGF; RAS; RAC; AKT; ERK; Neurite outgrowth