Keywords: بیمار; Urticaria; Biomarkers; CRP; IL-6; MPV; D-dimer; F1+2; Biologics; Omalizumab; ASCENT-I; ASCENT-II; GLACIAL; IL-1 antagonists; TNF-α inhibitors; Intravenous immunoglobulin; Rituximab; Ligelizumab; Quilizumab; ASST; Autologous serum skin test; ATA; Antithyr
مقالات ISI بیمار (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: بیمار; SYK; Spleen Tyrosine Kinase; Lead optimisation; Inhibitor; Skin penetration; Dermal;
Keywords: بیمار; AD; Alzheimer's disease; FTDP-17; frontotemporal dementia with parkinsonism linked to chromosome 17; GVD; granulovacuolar degeneration; GSK3β; glycogen synthase kinase-3β; NFTs; neurofibrillary tangles; pSyk; spleen tyrosine kinase phosphorylated at t
Keywords: بیمار; Syk; Renal fibrosis; Fibroblast; Macrophage; Immunohistochemistry; UUO
Keywords: بیمار; mammary gland; SYK; proliferation; AKT1;
Keywords: بیمار; Ab; Abelson; CD; Crohn's disease; CML; Chronic myeloid leukemia; DAI; Disease activity index; DC; Dentritic cell; IBD; Inflammatory bowel disease; IL; Interleukin; LGL; Large granular lymphocytosis; MDA; Malondialdehyde; MPO; Myeloperoxidase; NFкβ; Nucl
Keywords: بیمار; CARD; caspase recruitment domain; CLR; C-type lectin receptor; DC; dendritic cells; EAE; experimental autoimmune encephalitis; EAU; experimental autoimmune uveoretinitis; HEL; hen egg lysozyme; IRBP; interphotoreceptor retinal binding protein; MR; macroph
Keywords: بیمار; AC; adenylyl cyclase; AKT; protein kinase B; AMPK; AMP-activated protein kinase; AnR; androgen receptor; ARF6; ADP ribosylation factor 6; CaMK; Ca2+-calmodulin dependent kinase; CaMKK; CaMK kinase; cAMP; cyclic adenosine 3â²,5â²-monophosphate; CDK5; cyc
Keywords: بیمار; SCD; sickle cell disease; WT; wild type; CFSE; carboxyfluorescein succinimidyl ester; Prx2; peroxiredoxin 2; HSP; heat shock protein; MP; microparticle; NAC; N-acetylcysteine; HMC; hemichrome; PLB; phosphate lysis buffer; NEM; N-ethylmaleimide; FACS; fluo
Keywords: بیمار; ACE; angiotensin I converting enzyme; AGT; angiotensinogen; APOE; apolipoprotein E; APP; amyloid beta (A4) precursor protein; AR; androgen receptor; CADASIL; cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy; CST
Keywords: بیمار; Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange
Keywords: بیمار; Aβ; β-amyloid protein; AD; Alzheimer's disease; AP-1; Activator protein-1; AS; Atherosclerosis; CCl4; Carbon tetrachloride; CFA; Complete Freund's Adjuvant; CIA; Type II collagen-induced arthritis; CMM; Chinese Material Medica; Con A; Concanavalin A; CO
Keywords: بیمار; PAX5; BLIMP1; Phosphorylation; SYK; Plasma cell differentiation
Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression
Keywords: بیمار; Chimeric tyrosine kinases; Fusion genes; ITK; SYK; FER; Oncogenes;
Role of Malt1 protease activity in pathogenesis of inflammatory disorders mediated by FcγR signaling
Keywords: بیمار; BAC; bacteria artificial chromosome; BMDC; bone marrow-derived dendritic cell; CYLD; cylindromatosis; FBS; fetal bovine serum; FITC; fluorescein isothiocyanate; FcγR; Fcγ receptor; FcR; Fc receptor; GM-CSF; Granulocyte macrophage colony-stimulating fact
Furaltadone suppresses IgE-mediated allergic response through the inhibition of Lyn/Syk pathway in mast cells
Keywords: بیمار; Furaltadone; Mast cells; Syk; Allergy; Passive cutaneous anaphylaxis (PCA);
Discovery of novel Syk/PDGFR-α/c-Kit inhibitors as multi-targeting drugs to treat rheumatoid arthritis
Keywords: بیمار; Rheumatoid arthritis; Syk; PDGFR-α; c-Kit; Multi-targeting inhibitors; Dihydrofuropyrimidines;
Alisma canaliculatum ethanol extract suppresses inflammatory responses in LPS-stimulated macrophages, HCl/EtOH-induced gastritis, and DSS-triggered colitis by targeting Src/Syk and TAK1 activities
Keywords: بیمار; Alisma canaliculatum A.Braun & C.D.Bouché; Inflammatory diseases; Src; Syk; TAK1;
Pulsatilla decoction inhibits Candida albicans proliferation and adhesion in a mouse model of vulvovaginal candidiasis via the Dectin-1 signaling pathway
Keywords: بیمار; PD; Pulsatilla decoction; TCM; Traditional Chinese Medicine; VVC; Vulvovaginal candidiasis; HPLC; High performance liquid chromatography; CFU; Colony forming unit; PAS; Periodic acid schiff; H&E; Hematoxylin and eosin; SEM; Scanning electron microscopy; C
An Open-label, Phase II Trial of Entospletinib (GS-9973), a Selective Spleen Tyrosine Kinase Inhibitor, in Diffuse Large B-cell Lymphoma
Keywords: بیمار; B-cell receptor signaling inhibitors; DLBCL; Hematologic malignancies; Monotherapy; Syk;
Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies
Keywords: بیمار; NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o
Role of PTX3 in corneal epithelial innate immunity against Aspergillus fumigatus infection
Keywords: بیمار; PTX3; Aspergillus fumigatus; Cornea; HCECs; Syk; MAPK; IL-1β;
Orthopaedic implant materials drive M1 macrophage polarization in a spleen tyrosine kinase- and mitogen-activated protein kinase-dependent manner
Keywords: بیمار; Osteolysis; Wear particles; Macrophage polarization; Syk; MAPK;
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: بیمار; Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Flavonoids interfere with NLRP3 inflammasome activation
Keywords: بیمار; Flavonoid; NLRP3 inflammasome; Syk; Pyk2; Monosodium urate crystal;
Melatonin therapy for diabetic cardiomyopathy: A mechanism involving Syk-mitochondrial complex I-SERCA pathway
Keywords: بیمار; Melatonin; SERCA; COX-1; Syk; Diabetic cardiomyopathy;
Interaction of DJ-1 with Lyn is essential for IgE-mediated stimulation of human mast cells
Keywords: بیمار; Human mast cells; IgE receptor; Lyn activation; DJ-1; signaling; reactive oxygen species; spleen tyrosine kinase; Csk; C-terminal Src kinase; ERK; Extracellular signal-regulated kinase; HuMC; CD34+-derived human mast cell; JNK; c-Jun N-terminal kinase; LA
Src and Syk contribute to the anti-inflammatory activities of Achyranthes aspera ethanolic extract
Keywords: بیمار; Achyranthes aspera L.; Anti-inflammatory effect; NF-κB; Src; Syk;
SYK protects cardiocytes against anoxia and hypoglycemia-induced injury in ischemic heart failure
Keywords: بیمار; IHD; ischemic heart disease; IHF; ischemic heart failure; SYK; spleen tyrosine kinase; HO-1; heme oxygenase-1; ROS; reactive oxygen species; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; A/H; anoxia/hypoglycemic; TBS; tris-buffere
A novel whey tetrapeptide IPAV reduces interleukin-8 production induced by TNF-α in human intestinal Caco-2 cells
Keywords: بیمار; CaSR; calcium sensing receptor; ESI; electric spray ionization; HPLC; high-performance liquid chromatography; IBD; inflammatory bowel disease; IL; interleukin; ERK; extracellular signal-regulated kinase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; JN
Over expression of proteins that alter the intracellular signaling pathways in the cytoplasm of the liver cells forming Mallory-Denk bodies
Keywords: بیمار; Alcoholic hepatitis; SYK; AKT1; Mallory-Denk bodies;
Imaging flow cytometry and GST pulldown assays provide new insights into channel catfish leukocyte immune-type receptor-mediated phagocytic pathways
Keywords: بیمار; Phagocytosis; Immunoregulatory receptors; Intracellular signaling; Actin polymerization machinery; Imaging flow cytometry; Innate immunity; Channel catfish; Leukocyte immune-type receptors; IpLITR; channel catfish leukocyte immune-type receptor; CYT; cyto
Loss of discoidin domain receptor 1 (DDR1) via CpG methylation during EMT in epithelial ovarian cancer
Keywords: بیمار; DDR1; discoidin domain receptor 1; DDR2; discoidin domain receptor 2; EMT; epithelial-mesenchymal transition; EOC; epithelial ovarian cancer; RT-qPCR; reverse transcription quantitative polymerase chain reaction; ELISA; enzyme-linked immunosorbent assay;
Spleen tyrosine kinase mediates the actions of EPO and GM-CSF and coordinates with TGF-β in erythropoiesis
Keywords: بیمار; Syk; EPO; GM-CSF; Erythropoiesis; TGF-β; Hemoglobin;
Suppression of IgE-mediated mast cell activation and mouse anaphylaxis via inhibition of Syk activation by 8-formyl-7-hydroxy-4-methylcoumarin, 4μ8C
Keywords: بیمار; 8-Formyl-7-hydroxy-4-methylcoumarin; 4μ8C; Mast cells; Allergy; Anaphylaxis; Lyn; Fyn; BMMC; Bone marrow-derived mast cell; RBL; Rat basophilic leukemia; PCA; Passive cutaneous anaphylaxis; ITAM; Immunoreceptor tyrosine-based activation motif; DNP-BSA; D
Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK)
Keywords: بیمار; SYK; Kinase inhibitor; Kinase selectivity; Structure-based drug discovery; Leukemia; Lymphoma;
Synthesis and optimization of furano[3,2-d]pyrimidines as selective spleen tyrosine kinase (Syk) inhibitors
Keywords: بیمار; Spleen tyrosine kinase; Furano[3,2-d]pyrimidine; Syk; Rheumatoid arthritis; Kinase inhibitor;
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors
Keywords: بیمار; SYK; Spleen Tyrosine Kinase; Selective; Potent; Orally bioavailable; Azanaphthyridine; Lead optimisation; Medicinal chemistry;
E3 ubiquitin ligase CHIP interacts with C-type lectin-like receptor CLEC-2 and promotes its ubiquitin-proteasome degradation
Keywords: بیمار; CLEC-2; C-type lectin-like receptor 2; CHIP; C terminus of Hsc70-interacting protein; PMA; phorbol myristate acetate; CHX; cycloheximide; HEK293T; human emborynic kidney 293T; MS; mass spectrometry; FACS; fluorescence-activated cell sorting; ITAM; immunor
Grouper (Epinephelus coioides) BCR signaling pathway was involved in response against Cryptocaryon irritans infection
Keywords: بیمار; Epinephelus coioides; Cryptocaryon irritans; CD79; LYN; SYK
Cholesterol crystals activate Syk and PI3 kinase in human macrophages and dendritic cells
Keywords: بیمار; Cholesterol crystals; Inflammation; Syk; PI3K; S100 proteins; CHC; cholesterol crystals; Syk; spleen tyrosine kinase; PI3K; phosphoinositide-3 kinase; MMP; matrix metalloprotease; NLRP3; Nod-like receptor related protein 3; DAMPs; damage associated molecu
Syk negatively regulates TLR4-mediated IFNβ and IL-10 production and promotes inflammatory responses in dendritic cells
Keywords: بیمار; Syk; Toll-like receptor 4; Interferon-β; IL-10; PI3K; GSK3β;
Fifty years later: Emerging functions of IgE antibodies in host defense, immune regulation, and allergic diseases
Keywords: بیمار; IgE; mast cells; anaphylaxis; ADAM; A disintegrin and metalloproteinase; AID; Activation-induced cytidine deaminase; APC; Antigen-presenting cell; BAFF; BÂ cell-activating factor of the TNF family; CSR; Class-switch recombination; DC; Dendritic cell; DS
Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7
Keywords: بیمار; AKT/PKB; SYK; BLNK; Importin 7; 14-3-3; PHLPP; Nuclear translocation;
Spleen Tyrosine Kinase Mediates EGFR Signaling to Regulate Keratinocyte Terminal Differentiation
Keywords: بیمار; ITAM; immunoreceptor tyrosine-based activation motif; NHEK; normal human epidermal keratinocytes; PMA; phorbol 12-myristate 13-acetate; siRNA; small interfering RNA; Syk; spleen tyrosine kinase; TGase; transglutaminase;
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment
Keywords: بیمار; APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas
C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits
Keywords: بیمار; Spleen Tyrosine Kinase; DNA Methylation; Tumor Suppressor; Inflammatory Homeostasis; CES; composite expression score; CLEC2; C-type lectin-like receptor 2; EMT; epithelial to mesenchymal transition; GSK3; glycogen synthase kinase 3; IHC; immunohistochemis
Therapeutic effects of resveratrol in a mouse model of HDM-induced allergic asthma
Keywords: بیمار; Syk; spleen tyrosine kinase; HDM; house dust mite; FcεR; Fcε receptor; DEX; dexamethasone; BAY; BAY 61-3606; BALF; bronchoalveolar lavage fluid; DMSO; dimethyl sulfoxide; RBL-2H3; rat basophilic leukemia cell; PBS; phosphate buffered physiological salin
SYK expression endows human ZAP70-deficient CD8 T cells with residual TCR signaling
Keywords: بیمار; CID; ZAP70; SYK; TCR signaling; TREC newborn screening; Live vaccine adverse event;
Development and pharmacological validation of novel methods of B cell activation in rat whole blood
Keywords: بیمار; B cell; BTK; Dextran-coupled anti-IgD; Methods; PI3Kδ; Rat; Synergy; SYK; TLR9; Whole blood;