دانلود مقالات ISI درباره بیمار + ترجمه فارسی

Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms

Keywords: بیمار; IpLITRs; Ictalurus punctatus leukocyte immune-type receptors; SH2; Src homology 2; SHP; Src homology 2 domain-containing cytoplasmic phosphatase; Csk; C-terminal Src kinase; ITAM; immune receptor tyrosine-based activation motif; SFK; Src-family protein ty

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

The safety and efficacy of sublingual and oral immunotherapy for milk allergy

Keywords: بیمار; Food allergy; immunotherapy; milk allergy; basophil; spontaneous histamine release; BEC; Basophil-enriched mononuclear cell; DBPCFC; Double-blind, placebo-controlled food challenge; CM; Cow's milk; HR; Histamine release; IRR; Incidence rate ratio; MFI;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Immune response modifiers in the treatment of asthma: A PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

Keywords: بیمار; Immune response modifiers; monoclonal antibodies; asthma; allergic diseases; APC; Antigen-presenting cell; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells (also known as DP2); FDA; US Food and Drug Administration; Feno; Fraction

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

The Syk/CARD9-coupled receptor Dectin-1 is not required for host resistance to Mycobacterium tuberculosis in mice

Keywords: بیمار; C-type lectin receptors; Syk; CARD9; Dectin-1; Pulmonary disease; Inflammation;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

The microenvironment in mantle cell lymphoma: Cellular and molecular pathways and emerging targeted therapies

Keywords: بیمار; Mantle cell lymphoma (MCL); Microenvironment; CXCR4; CXCR5; BTK; SYK; PI3 K;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibitory effects of flavonoid glycosides isolated from the peel of Japanese persimmon (Diospyros kaki Fuyu) on antigen-stimulated degranulation in rat basophilic leukaemia RBL-2H3 cells

Keywords: بیمار; Ag; antigen; BSA; bovine serum albumin; CM-H2DCF-DA; 5-(and-6-)-carboxy-2′,7′-dichlorodihydrofluorescein diacetat; DNP; dinitrophenol; DPPH; 1,1-diphenyl-2-picrylhydrazyl; DPI; diphenyleneiodonium chloride; EGCG; (−)-epigallocatechin gallate; ERK; e

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of BCAR-1 as a new substrate of Syk tyrosine kinase through a determination of amino acid sequence preferences surrounding the substrate tyrosine residue

Keywords: بیمار; Syk; Tyrosine kinase; Signal transduction; BCAR-1; In vitro kinase assay

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

4-Chlorotetrazolo[1,5-a]quinoxaline inhibits activation of Syk kinase to suppress mast cells in vitro and mast cell-mediated passive cutaneous anaphylaxis in mice

Keywords: بیمار; 4-Chlorotetrazolo[1,5-a]quinoxaline; Mast cells; Syk; Allergy; Passive cutaneous anaphylaxis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

MiR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4

Keywords: بیمار; miRNAs; microRNAs; oxLDL; oxidized low-density lipoprotein; TLR2; toll-like receptor 2; TLR3; toll-like receptor 3; TLR4; toll-like receptor 4; TLRs; toll-like receptors; IL-6; interleukin 6; IL-8; interleukin 8; MCP-1; chemokine (C-C motif) ligand 2; M

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor

Keywords: بیمار; Spleen; Tyrosine; Kinase; Inhibitor; Herg; SYK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways

Keywords: بیمار; Psoralidin; LPS; Syk; PI3K; IKK; NF-κB; iNOS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Ethyl acetate extract of Psidium guajava inhibits IgE-mediated allergic responses by blocking FcεRI signaling

Keywords: بیمار; Psidium guajava; Anti-allergic activity; Mast cells; IL-4; NF-κB; Syk;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans

Keywords: بیمار; Pa-EE; ethanol extract of Phaseolus angularis; LPS; lipopolysaccharide; NO; nitric oxide; PG; prostaglandin; iNOS; inducible NO synthase; COX; cyclooxy-genase; IL; interleukin; IKK; I (B) kinase; Akt; protein kinase B; PDK; phosphoinositide-dependent kina

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Mast cell signaling: The role of protein tyrosine kinase Syk, its activation and screening methods for new pathway participants

Keywords: بیمار; Mast cell; FcεRI signal transduction; Syk; Fyn; Gab2; Phosphatase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Syk and Zap-70 function redundantly to promote angioblast migration

Keywords: بیمار; Syk; Zap-70; Vegf; Intersegmental vessel; Thoracic duct; Migration; Angioblast; Zebrafish;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The Src, Syk, and Tec family kinases: Distinct types of molecular switches

Keywords: بیمار; Syk; Zap-70; Btk; Itk; Kinase; Switch

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Anti-inflammatory actions of Syk inhibitors in macrophages involve non-specific inhibition of toll-like receptors-mediated JNK signaling pathway

Keywords: بیمار; Innate immunity; TLR; Syk; Syk inhibitors; Inflammatory cytokines

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Food allergy herbal formula 2 protection against peanut anaphylactic reaction is via inhibition of mast cells and basophils

Keywords: بیمار; Peanut anaphylaxis; Chinese herbal medicine; mast cells/basophils; FcεRI; CT; Cholera toxin; DMEM; Dulbecco modified Eagle medium; FAHF-2; Food allergy herbal formula 2; FITC; Fluorescein isothiocyanate; MFI; Mean fluorescent intensity; PBLC; Peripheral

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

A Multitude of Kinases-Which are the Best Targets in Treating Rheumatoid Arthritis?

Keywords: بیمار; MAPKs; Tyrosine kinases; IKK; Jak; Syk; Small-molecule inhibitors;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Characterization of an early signaling defect following FcɛRI activation in the canine mastocytoma cell line, C2

Keywords: بیمار; BSA; bovine serum albumin; C2; canine mastocytoma cell line; cFcɛRIα; canine IgE high-affinity receptor alpha subunit; DMEM; Dulbecco's modified Eagle's medium; DNP-HSA; dinitrophenol coupled to human serum albumin; FBS; fetal bovine serum; FcR-γ; Fc r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

ZAP-70 and Syk expression in canine lymphoid cells and preliminary results on leukaemia cases

Keywords: بیمار; Dog; ZAP-70; Syk; Real-time PCR; Leukocyte; Leukaemia

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibitory mechanism of saponins derived from roots of Platycodon grandiflorum on anaphylactic reaction and IgE-mediated allergic response in mast cells

Keywords: بیمار; Platycodon grandiflorum; Anti-allergic activity; Mast cells; Passive cutaneous anaphylaxis; Syk; NF-κB;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Association between reduced levels of total serum IgE and FcεRI expression in non-releaser basophils

Keywords: بیمار; Basophils; Histamine non-releasers; IgE; FcεRI; Lyn; Syk

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Conformational rearrangements upon Syk auto-phosphorylation

Keywords: بیمار; Single-particle electron microscopy; EM; Syk; ZAP-70; Tyrosine kinase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Houttuynia cordata water extract suppresses anaphylactic reaction and IgE-mediated allergic response by inhibiting multiple steps of FcεRI signaling in mast cells

Keywords: بیمار; Houttuynia cordata; Anti-allergic activity; Mast cells; Passive cutaneous anaphylaxis; Syk; NF-κB

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Characterization of clathrin and Syk interaction upon Shiga toxin binding

Keywords: بیمار; Shiga toxin; Clathrin; Endocytosis; Syk; Lymphocyte

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Steroid effects on ZAP-70 and SYK in relation to apoptosis in poor prognosis chronic lymphocytic leukemia

Keywords: بیمار; Chronic lymphocytic leukemia; ZAP-70; SYK; Glucocorticoids; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling

Keywords: بیمار; Epstein–Barr virus (EBV); Latent membrane protein 2A (LMP2A); c-Cbl; Lyn; Syk; Ubiquitin; Lytic replication

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Endosomal trafficking of the ligated FcɛRI receptor

Keywords: بیمار; FcɛRI; Endosomes; Co-localization; Syk

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Dectin-1 is required for human dendritic cells to initiate immune response to Candida albicans through Syk activation

Keywords: بیمار; Dectin-1; Dendritic cells; C. albicans; Syk; Cytokine; Immune response

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Structure–activity relationship studies of 5-benzylaminoimidazo[1,2-c]pyrimidine-8-carboxamide derivatives as potent, highly selective ZAP-70 kinase inhibitors

Keywords: بیمار; Syk family kinase; Syk; ZAP-70; T cell immunoresponse; Immunosuppressant; Selective ZAP-70 inhibitor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Distinct role of spleen tyrosine kinase in the early phosphorylation of inhibitor of κBα via activation of the phosphoinositide-3-kinase and Akt pathways

Keywords: بیمار; LPS-induced inflammatory response; Non-receptor type protein tyrosine kinases; IκBα; Syk; Macrophages;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Kinetic assay for characterization of spleen tyrosine kinase activity and inhibition with recombinant kinase and crude cell lysates

Keywords: بیمار; Tyrosine kinase; Fluorescent assay; Kinetics; Syk; RAMOS cells

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Syk and pTyr'd: Signaling through the B cell antigen receptor

Keywords: بیمار; Syk; B cell activation; Antigen receptor; Protein-tyrosine kinase; Protein phosphorylation; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

Expression of RAC2 in endothelial cells is required for the postnatal neovascular response

Keywords: بیمار; BMEC, bone marrow derived endothelial cells; EC, endothelial cells; MEF, mouse embryo fibroblasts; VN, vitronectin; FN, fibronectin; LDPI, Laser Doppler Perfusion ImagingEndothelial cells; RAC2; SYK; Integrin; Angiogenesis

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)

Keywords: بیمار; SYK; Spleen tyrosine kinase; Asthma

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

The microtubule-associated protein tau is phosphorylated by Syk

Keywords: بیمار; Tau; Tyrosine phosphorylation; Syk; Tauopathy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Evaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets

Keywords: بیمار; OXSI-2; Syk; Src; GPVI signaling; PAR and Piceatannol;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

A photoswitchable ITAM peptidomimetic: Synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis–trans isomerization on binding

Keywords: بیمار; FcεRI; Syk; ITAM; SH2; Azobenzene; Conformational photoswitch; Surface plasmon resonance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Syk inhibitors as treatment for allergic rhinitis

Keywords: بیمار; Allergic rhinitis; Syk; Kinase inhibitor; Mast cells; IgE receptor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally

Keywords: بیمار; Allergy and inflammation; anaphylactic shock; degranulation; druglike compound; mast cells/basophils; tyrosine kinase; Syk; BMMC; Bone marrow-derived mast cell; C-13; Compound 13; ITAM; Immunoreceptor tyrosine-based activation motif; LAT; Linker for act

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk

Keywords: بیمار; CFU, colony forming unit; MAPK, mitogen-activated protein kinase; MOI, multiplicity of infection; PI3K, phosphatidylinositol 3 kinaseFrancisella; Syk; PI3K/Akt; Erk; Phagocytosis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Kit- and FcɛRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cells

Keywords: بیمار; Mast cells; FcɛRI; Kit; NTAL; Lyn; Syk; Signaling; Adaptor molecules;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

A novel Syk family kinase inhibitor: Design, synthesis, and structure–activity relationship of 1,2,4-triazolo[4,3-c]pyrimidine and 1,2,4-triazolo[1,5-c]pyrimidine derivatives

Keywords: بیمار; Protein tyrosine kinases (PTKs); Syk; ZAP-70; Syk and/or ZAP-70 kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Inducing an anergic state in mast cells and basophils without secretion

Keywords: بیمار; Desensitization; spleen tyrosine kinase; phosphatidyl-inositol 3′ kinase; HSA; Human serum albumin; LT; Leukotriene; PI3K; Phosphatidyl inositol 3′ kinase; SHIP; Src homology domain 2-containing inositol phosphatase; syk; Spleen tyrosine kinase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

A mouse Fcγ-Fcε protein that inhibits mast cells through activation of FcγRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases

Keywords: بیمار; FcγRIIB; mast cell inhibition; FcεRI signaling; BMMC; Bone marrow-derived mast cells; DNP; Dinitrophenyl; ERK; Extracellular signal-regulated kinase; hGE2; Human GE2; ITIM; Immunoreceptor tyrosine-based inhibitory motif; mGE; Mouse homolog of human GE

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Structure–activity relationship studies of imidazo[1,2-c]pyrimidine derivatives as potent and orally effective Syk family kinases inhibitors

Keywords: بیمار; Protein tyrosine kinases (PTKs); Syk family kinases; Syk; ZAP-70; Autoimmune diseases; Syk and/or ZAP-70 kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

New Drugs for the Treatment of Lymphoma

Keywords: بیمار; New drugs; Bcl-2; Lymphoma; Syk; Pralatrexate;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2008 سفارش ترجمه

Infections, B cell receptor activation and autoimmunity: Different check-point impairments lead to autoimmunity, clonal B cell expansion and fibrosis in different immunological settings

Keywords: بیمار; B cell receptor; Inhibiting kinases; Activating kinases; Lyn; Syk; Chronic lymphocytic leukaemia; Hepatitis C; SLE; RA; SSc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Evidence of LAT as a dual substrate for Lck and Syk in T lymphocytes

Keywords: بیمار; LAT; Lck; Syk; Zap70; T lymphocytes

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه