دانلود مقالات ISI درباره فسفینوزیتید 3-کیناز + ترجمه فارسی

Targeting autophagy as a potential therapeutic approach for melanoma therapy

Keywords: فسفینوزیتید 3-کیناز; 5-ALA; 5-aminolevulinic acid; AMBRA1; autophagy/Beclin 1 regulator 1; APC; antigen-presenting cell; ASS; argininosuccinate synthetase; ATG; autophagy-related; ATM; Ataxia telangiectasia mutated; BafA1; bafilomycin A1; Bif-1; endophilin B1; BN; benign nevi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery and optimization of a series of 2-aminothiazole-oxazoles as potent phosphoinositide 3-kinase γ inhibitors

Keywords: فسفینوزیتید 3-کیناز; Phosphoinositide 3-kinase; PI3Kγ inhibitor; 2-Aminothiazole-oxazoles;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress

Keywords: فسفینوزیتید 3-کیناز; CoCl2; cobalt chloride; DIC; differential interference contrast; DiI; 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; GSK-3; glycogen synthase kinase 3; HIF-1; hypoxia-inducible factor-1; LPS; lipopolysaccharide; Mal; MyD88 adapt

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

(−)-Epigallocatechin-3-gallate stimulates both AMP-activated protein kinase and nuclear factor-kappa B signaling pathways

Keywords: فسفینوزیتید 3-کیناز; EGCG; (−)-epigallocatechin-3-gallate; SHARP; enhancer of split- and hairy-related protein; PEPCK; phosphoenolpyruvate carboxykinase; PI 3-K; phosphoinositide 3-kinase; aPKCλ; atypical protein kinase C lambda; AMPK; AMP-activated protein kinase; NF-κB;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of 4-morpholino-pyrimidin-6-one and 4-morpholino-pyrimidin-2-one-containing Phosphoinositide 3-kinase (PI3K) p110β isoform inhibitors through structure-based fragment optimisation

Keywords: فسفینوزیتید 3-کیناز; Fragment-based; Phosphoinositide 3-kinase; PI3K; p110β; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery of phosphoinositide 3-kinases (PI3K) p110β isoform inhibitor 4-[2-hydroxyethyl(1-naphthylmethyl)amino]-6-[(2S)-2-methylmorpholin-4-yl]-1H-pyrimidin-2-one, an effective antithrombotic agent without associated bleeding and insulin resistance

Keywords: فسفینوزیتید 3-کیناز; Fragment-based; Phosphoinositide 3-kinase; PI3K; p110β; Inhibitor; Thromboembolism; Anti-thrombotic agent; Insulin resistance;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Receptor fusion proteins for the inhibition of cytokines

Keywords: فسفینوزیتید 3-کیناز; Akt; a serine-threonine protein kinase; Bcr-Abl; fusion of the breakpoint cluster region (bcr) gene and a cellular Abelson murine leukemia viral oncogene homolog; CAPS; cryopyrin-associated periodic syndromes; CBM; cytokine binding module; CLC; cardiotr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Cyclic AMP-specific phosphodiesterase, PDE8A1, is activated by protein kinase A-mediated phosphorylation

Keywords: فسفینوزیتید 3-کیناز; PDE8; phosphodiesterase 8; PKA; protein kinase A; cAMP; cyclic-AMP; PI3K; phosphoinositide 3-kinase; DNAPK; DNA_dependent protein kinase; FSK; forskolin; EPAC; exchange protein directly activated by cAMP; cGMP; cyclic guanine monophosphate; PDE8; PKA; cAM

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Functional significance of glycogen synthase kinase-3 regulation by serotonin

Keywords: فسفینوزیتید 3-کیناز; FST; forced swim test; GSK3; glycogen synthase kinase-3; 5-HT1A; serotonin type 1A receptors; i.p.; intraperitoneal; KI; knock-in; PI3K; phosphoinositide 3-kinase; PKA; protein kinase A; PKC; protein kinase C; WT; wild type; Serotonin; 5-HT1A; Fluoxetine;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Insulin-like growth factor-1 (IGF-1) inhibits the basolateral Cl channels in the thick ascending limb of the rat kidney

Keywords: فسفینوزیتید 3-کیناز; Phosphoinositide 3-kinase; PKD; AKT; mTOR; Cl transport;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold

Keywords: فسفینوزیتید 3-کیناز; Phosphoinositide 3-kinase; Mammalian target of rapamycin; PI3K; mTOR; Sulfonamide; Triazine; Oncology;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Analysis of regulatory mechanisms of an insulin-inducible SHARP-2 gene by (S)-Equol

Keywords: فسفینوزیتید 3-کیناز; SHARP-2; Transcription factor; Insulin; (S)-Equol; Phosphoinositide 3-kinase; Protein kinase C

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleHO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: Regulation of TLR4 innate responses through PI3K/PTEN signaling

Keywords: فسفینوزیتید 3-کیناز; Ad-HO-1; recombinant adenovirus encoding hemeoxygenase-1; Ad-β-gal; recombinant adenovirus β-galactosidase reporter gene; BMMs; bone marrow derived-macrophages; IRI; ischemia/reperfusion injury; MPO; myeloperoxidase; PI3K; phosphoinositide 3-kinase; PTE

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Scaffold protein Homer 1: Implications for neurological diseases

Keywords: فسفینوزیتید 3-کیناز; EVH1; Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) homology 1; IEG; immediate-early gene; P motif; proline-containing motif; mGluR; metabotropic glutamate receptor; IP3R; inositol 1,4,5-trisphosphate receptor; TRPC; transient receptor potentia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Negative regulation of human U6 snRNA promoter by p38 kinase through Oct-1

Keywords: فسفینوزیتید 3-کیناز; PMA; phorbol 12-myristate 13-acetate; snRNA; small nuclear RNA; RNA Pol III; RNA polymerase III; PSE; proximal sequence element; DSE; distal sequence element; SNAPc; snRNA activating-protein complex; MAPK; mitogen-activated protein kinase; ERKs; extracell

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

A high-selenium diet induces insulin resistance in gestating rats and their offspring

Keywords: فسفینوزیتید 3-کیناز; Akt2; serine/threonine protein kinase 2; BD; basal diet; FPG; fasting plasma glucose; FPI; fasting plasma insulin; FoxO1; forkhead box O1; Gapdh; glyceraldehyde-3-phosphate dehydrogenase; GDM; gestational diabetes mellitus; Gpx; glutathione peroxidase; HO

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Eucommia ulmoides Oliv. Bark. protects against hydrogen peroxide-induced neuronal cell death in SH-SY5Y cells

Keywords: فسفینوزیتید 3-کیناز; EUE; Eucommia ulmoides Oliv. Bark.; H2O2; Hydrogen peroxide; HLC; High-performance liquid chromatography; ROS; Reactive oxygen species; MMP; Mitochondria membrane potential; PARP; Poly-ADP-ribose polymerase; JNK; C-Jun N-terminal kinase; MAPK; Mitogen-act

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Schizandrin prevents damage of murine mesangial cells via blocking NADPH oxidase-induced ROS signaling in high glucose

Keywords: فسفینوزیتید 3-کیناز; DN; diabetic nephropathy; DCF; 2′,7′-dichlorofluorescein; DMEM; Dulbecco's modified Eagle's medium; DPI; diphenylene iodonium; ECM; extracellular matrix; Erk1/2; extracellular signal-regulated kinase 1/2; HG; high glucose; HM; high mannitol; MAPK;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death

Keywords: فسفینوزیتید 3-کیناز; PD; Parkinson's disease; GSK3β; glycogen synthase kinase-3β; PI3K; phosphoinositide 3-kinase; SN; Substantia Nigra; ROS; reactive oxidative species; MPP+; 1-methyl-4-phenylpyridinium iodide; Puerarin; PI3K/Akt pathway; p53; Caspase-3;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The catalytic phosphoinositol 3-kinase isoform p110δ is required for glioma cell migration and invasion

Keywords: فسفینوزیتید 3-کیناز; Phosphoinositide 3-kinase; p110δ; Glioma; Migration; Invasion

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The Drosophila larva as a tool to study gut-associated macrophages: PI3K regulates a discrete hemocyte population at the proventriculus

Keywords: فسفینوزیتید 3-کیناز; Haemocyte; Gut; Intestine; Innate immunity; Insect; Migration; Phagocytosis; PV; proventriculus; L3W; L3 wandering larvae; DH31; diuretic hormone 31; PI3K; phosphoinositide 3-kinase; DN; dominant negative; CA; constitutively active;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Sphingosine 1-phosphate-mediated α1B-adrenoceptor desensitization and phosphorylation. Direct and paracrine/autocrine actions

Keywords: فسفینوزیتید 3-کیناز; NA; noradrenaline; AR; adrenergic receptor; PKC; protein kinase C; PI3K; phosphoinositide 3-kinase; S1P; sphingosine 1-phosphate; SPHK-1; sphingosine kinase-1; eGFP; enhanced green fluorescent protein; α1B-Adrenoceptor; α1B-Adrenergic receptor; Sphingos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Staurosporine-induced apoptosis presents with unexpected cholinergic effects in a differentiated neuroblastoma cell line

Keywords: فسفینوزیتید 3-کیناز; AChE; acetylcholinesterase; AChE-T; tailed AChE; AChE-R; readthrough AChE; AMP-PNP; adenosine 5′-(β,γ-imido)triphosphate; AV; Annexin V-FITC; ChAT; choline acetyltransferase; FBS; fetal bovine serum; HACU; high affinity choline uptake; HC-3; hemicholi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Bcl-w promotes cell invasion by blocking the invasion-suppressing action of Bax

Keywords: فسفینوزیتید 3-کیناز; DCF; 2′,7′-dichlorofluorescein; MEF; mouse embryonic fibroblasts; MMP-2; matrix metalloproteinase-2; NAC; N-acetyl-cysteine; PI3K; phosphoinositide 3-kinase; ROS; reactive oxygen species; Bcl-2 family; Cell death; Cell invasion;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The role of amino acid transporters in GSH synthesis in the blood-brain barrier and central nervous system

Keywords: فسفینوزیتید 3-کیناز; AA; amino acid; AARE; amino acids response elements; ApN; aminopeptidase N; ARE; antioxidant response element; BBB; blood-brain barrier; BEC; brain endothelial cell; CNS; central nervous system; CSF; cerebrospinal fluid; EC; endothelial cell; ERK; extra

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The phosphoinositide 3-kinase inhibitor LY294002, decreases aminoacyl-tRNA synthetases, chaperones and glycolytic enzymes in human HT-29 colorectal cancer cells

Keywords: فسفینوزیتید 3-کیناز; CRC; colorectal cancer; DMSO; dimethyl sulfoxide; ECL; enhanced chemiluminescence; ESI; electrospray ionization; FCS; fetal calf serum; HRP; horse-radish peroxidase; IC50; half maximal inhibitory concentration; IEF; isoelectric focusing; IPG; immobilized

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of persistent activation of phosphoinositide 3-kinase on heart

Keywords: فسفینوزیتید 3-کیناز; Insulin; Phosphoinositide 3-kinase; Gene expression; Aging;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Activation of Akt/FoxO and inactivation of MEK/ERK pathways contribute to induction of neuroprotection against transient global cerebral ischemia by delayed hypoxic postconditioning in adult rats

Keywords: فسفینوزیتید 3-کیناز; Cerebral ischemia; Hypoxia; Neuroprotection; Postconditioning; Signal pathways; IT; Ischemic tolerance; I/R; ischemia and reperfusion; IPC; ischemic postconditioning; HPC; hypoxic postconditioning; OGD; oxygen glucose deprivation; tGCI; transient global c

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

IL-13 dampens human airway epithelial innate immunity through induction of IL-1 receptor-associated kinase M

Keywords: فسفینوزیتید 3-کیناز; IL-13; IL-1 receptor-associated kinase M; Toll-like receptor 2; airway epithelial cells; ALI; Air-liquid interface; AP-1; Activator protein 1; BEGM; Bronchial epithelial cell growth medium; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; hBD2; Human β

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)

Keywords: فسفینوزیتید 3-کیناز; ARE; Antioxidant response element; DCF; 2′,7′-dichlorofluorescein; DDC; 2′,3′-dihydroxy-4′,6′-dimethoxychalcone; DHE; Dihydroethidium; DMSO; Dimethyl sulfoxide; EI; Electron impact; ETH; Ethidium; γ-GCS; ⁎γ-glutamylcysteine synthetase; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

Keywords: فسفینوزیتید 3-کیناز; AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Sp1 is involved in regulation of cystathionine γ-lyase gene expression and biological function by PI3K/Akt pathway in human hepatocellular carcinoma cell lines

Keywords: فسفینوزیتید 3-کیناز; CSE; cystathionine γ-lyase; PLP; pyridoxal-5′-phosphate; PI3K; phosphoinositide 3-kinase; Myr-Akt2; myristylated variants of Akt2; IGF-1; insulin-like growth factor-1; PTEN; phosphatase and tensing homolog; CHX; cycloheximide; MEF; mouse embryonic fibr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Perspectives des thérapies ciblées dans le cancer du sein métastatique

Keywords: فسفینوزیتید 3-کیناز; thérapie ciblée; cancer du sein métastatique; HER-2; anti-angiogénèse; étude clinique; targeted therapy; metatstatic breast cancer; HER-2; anti-agiogenesis; clinical trial; ADCC; cytotoxicité à médiation cellulaire anticorps-dépendante; Akt; pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

IL-33 induces innate lymphoid cell-mediated airway inflammation by activating mammalian target of rapamycin

Keywords: فسفینوزیتید 3-کیناز; IL-33; TH2; innate lymphoid cells; asthma; mammalian target of rapamycin; rapamycin; AHR; Airway hyperresponsiveness; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; Lin; Lineage-specific marker;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Campylobacter jejuni Induces Colitis Through Activation of Mammalian Target of Rapamycin Signaling

Keywords: فسفینوزیتید 3-کیناز; Crypt Abscesses; Imaging; Mouse Model; Immune Response; Signal Transduction; CFU; colony-forming unit; EGFP; enhanced green fluorescent protein; FISH; fluorescence in situ hybridization; IL; interleukin; MLN; mesenteric lymph node; mTOR; mammalian target

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Using mice to unveil the genetics of cancer resistance

Keywords: فسفینوزیتید 3-کیناز; AC; adenocarcinoma; AOM; azoxymethane; APC; antigen-presenting cells; BH; BCL2 homology; CCl4; carbon tetrachloride; cM; centimorgan; COX; cyclo-oxygenase; CTLA-4; cytotoxic T-lymphocyte antigen 4; DC; dendritic cells; DEN; diethylnitrosamine; DMBA; 7,12-

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Concanavalin A: A potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics

Keywords: فسفینوزیتید 3-کیناز; BHA; butylated hydroxyanisole; BNIP3; adenovirus E1B 19 kDa-interacting protein 3; ConA; Concanavalin A; COX-2; cyclooxygenase-2; Cyto c; cytochrome c; DAPK; dual-specificity protein kinase; ERK; extracellular signal-regulated kinase; MAPK; mitogen-activ

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Genes that integrate multiple adipogenic signaling pathways in human mesenchymal stem cells

Keywords: فسفینوزیتید 3-کیناز; Functional genomics; Adipogenesis; Human mesenchymal stem cell; Gene screening; Multiple pathway communication; hMSCs; human mesenchymal stem cells; Dex; dexamethasone; IBMX; 3-isobutyl-1-methylxanthine; C/EBP; CCAAT/enhancer-binding protein; PPARγ; pero

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Receptor mediated endocytosis 8 is a novel PI(3)P binding protein regulated by myotubularin-related 2

Keywords: فسفینوزیتید 3-کیناز; MALDI-MS; matrix-assisted laser desorption ionization-mass spectrometry; TOF; time of flight; PTP; protein tyrosine phosphatase; RME-8; receptor mediated endocytosis 8; Hsc70; heat shock cognate 70; MTMR2; myotubularin related protein 2; PIP; phosphatidyl

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Prevention of the wortmannin-induced inhibition of phosphoinositide 3-kinase by sulfhydryl reducing agents

Keywords: فسفینوزیتید 3-کیناز; wortmannin; sulfhydryl reducing agent; phosphoinositide 3-kinase; PI3K; 2-mercaptoethanol; dithiothreitol

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Sensitizing effect of 3-methyladenine on radiation-induced cytotoxicity in radio-resistant HepG2 cells in vitro and in tumor xenografts

Keywords: فسفینوزیتید 3-کیناز; Liver cancer; Radio-resistance; Autophagy; 3-MA; 3-methyladenine; AO; acridine orange; AVOs; acidic vesicular organelles; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HCC; hepatocellular carcinoma; IR; ionizing radiation; mTOR; mammalian target of rap

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

iNOS/NO signaling regulates apoptosis induced by glycochenodeoxycholate in hepatocytes

Keywords: فسفینوزیتید 3-کیناز; iNOS; inducible nitric oxide synthase; NO; nitric oxide; GCDC; glycochenodeoxycholate; SNAP; S-nitroso-N-acetyl-penicillamine; SNP; sodium nitroprusside; PI3K; Phosphoinositide 3-kinase; NF-κB; nuclear factor kappaB; p38MAPK; P38 mitogen-activated protei

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The localisation of PtdIns3P in Drosophila fat responds to nutrients but not insulin: a role for Class III but not Class II phosphoinositide 3-kinases

Keywords: فسفینوزیتید 3-کیناز; AEL; after egg lay; eL3; early third larval instar; hVps15; mammalian vacuolar protein sorting 15 homologue; hVps34; mammalian vacuolar protein sorting 34 homologue; L3; third larval instar; MTM; myotubularin; PI3K; phosphoinositide 3-kinase; S6K1; S6 kin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

TH17 cytokines induce human airway smooth muscle cell migration

Keywords: فسفینوزیتید 3-کیناز; Asthma; airway remodeling; TH17; airway smooth muscle cells; migration; ASM; Airway smooth muscle; ASMC; Airway smooth muscle cell; IκBα; Nuclear factor of κ light polypeptide gene enhancer in B-cells inhibitor, α; MAPK; Mitogen-activated protein kina

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Tumor necrosis factor-α increases angiopoietin-like protein 2 gene expression by activating Foxo1 in 3T3-L1 adipocytes

Keywords: فسفینوزیتید 3-کیناز; TNF-α; tumor necrosis factor-α; IRE; insulin response element; FBE; Fox binging element; Foxo1; forkhead box o1; C/EBP; CCAAT/enhancer binding protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; RACE; rapid amplification of cDNA ends; shRNA; short

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Nuclear β-adrenergic receptors modulate gene expression in adult rat heart

Keywords: فسفینوزیتید 3-کیناز; AC; adenylyl cyclase; ATP; adenosine triphosphate; βAR; β-adrenergic receptor; CAMKII; Ca2+/calmodulin-dependent protein kinase II; DNA; deoxyribonucleic acid; DTT; dithiothreitol; ET-1; endothelin 1; ERK; extracellular signal-regulated kinase; GPCR; G

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1

Keywords: فسفینوزیتید 3-کیناز; AMPK; AMP-activated protein kinase; HEK293; human embryo kidney 293 cells; IIS; insulin/insulin-like signaling; IRS; insulin receptor substrate; MAPK; mitogen activated protein kinase; PGC-1α; PPARγ general co-activator 1α; PI3K; phosphoinositide 3-kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting autophagy during cancer therapy to improve clinical outcomes

Keywords: فسفینوزیتید 3-کیناز; AMPK; AMP activated protein kinase; ATG; autophagy-related genes; Bif-1; endophilin B1; BNIP3; Bcl-2/adenovirus E1B 19 kDa-interacting protein; CML; chronic myeloid leukemia; CQ; chloroquine; DAP1; death-associated protein 1; HCQ; hydroxychloroquine; HDA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting PI3K Signaling as a Therapeutic Approach for Colorectal Cancer

Keywords: فسفینوزیتید 3-کیناز; Colon Cancer; Neoplasm; Signal Transduction; Genetics; Tumor; CRC; colorectal cancer; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; GPCR; G-protein-coupled receptor; IRS1; insulin receptor substrate 1; MEF; murine embryonic fibro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting phosphoinositide 3-kinase signalling in lung cancer

Keywords: فسفینوزیتید 3-کیناز; Non-small cell lung cancer; Small cell lung cancer; Phosphoinositide 3-kinase; Akt; Mammalian target of rapamycin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه