The impact of ion-pairing reagents on the selectivity and sensitivity in the analysis of modified oligonucleotides in serum samples by liquid chromatography coupled with tandem mass spectrometry
Keywords: oligonucleotides فسفروتیوات; Phosphorothioate oligonucleotides; Ion pair reversed phase chromatography; Separation; Tandem mass spectrometry; Amine ion-pairing reagent; Serum;