Keywords: نشانه Photoafinity; Glycolipid; Photoaffinity labeling; Photoaffinity probes; Benzophenone; Diazirine;
مقالات ISI نشانه Photoafinity (ترجمه نشده)
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Keywords: نشانه Photoafinity; Photoaffinity labeling; Protein–lipid interaction; Proteomics; Imaging; Click chemistry
Design and synthesis of small molecule-conjugated photoaffinity nanoprobes for a streamlined analysis of binding proteins
Keywords: نشانه Photoafinity; Photoaffinity labeling; Small-molecule binding proteins; Gold nanoparticles; Nanoprobes; Water dispersibility;
Design, synthesis and evaluation of photoactivatable derivatives of microtubule (MT)-active [1,2,4]triazolo[1,5-a]pyrimidines
Keywords: نشانه Photoafinity; Triazolopyrimidine; Microtubule stabilization; Photoaffinity labeling; CNS drug discovery;
Clickable photoaffinity ligands for the human serotonin transporter based on the selective serotonin reuptake inhibitor (S)-citalopram
Keywords: نشانه Photoafinity; Citalopram; Selective serotonin reuptake inhibitor; Serotonin transporter; Photoaffinity labeling; Click chemistry;
Development of a novel photoaffinity probe for labeling nocistatin receptor
Keywords: نشانه Photoafinity; Nocistatin; Receptor; Photoaffinity labeling; Pain; Allodynia; Spinal cord;
Photoactivatable oligonucleotide probes to trap single-stranded DNA binding proteins: Updating the potential of 4-thiothymidine from a comparative study
Keywords: نشانه Photoafinity; Photoaffinity labeling; Single-stranded DNA binding proteins; Human replication protein A; 4-thiothymidine; EMSA; electrophoretic mobility shift assays; MALDI-TOF MS; Matrix assisted laser desorption/Ionisation time-of-flight mass spectrometry; ODN; oligo
Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs
Keywords: نشانه Photoafinity; CFT (PubChem CID 105056); Dopamine HCl (PubChem CID 65340); RTI 82 (PubChem CID 132374); G418 (PubChem CID 123865); Cocaine (PubChem CID 446220); Mazindol (PubChem CID 4020); Dopamine transporter; Photoaffinity labeling; Addiction; Cocaine; Computational
Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor
Keywords: نشانه Photoafinity; Cannabinoid receptor; Allosteric modulator; Photoaffinity labeling; Photoactivatable ligands; CB1; Cannabinoid type 1 receptor; GPCR; G-protein coupled receptor; nAChRs; nicotinic acetylcholine receptors; BP; benzophenone; PTFMD; phenyltrifluoromethyldiaz
Structure-assisted ligand-binding analysis using fluorogenic photoaffinity labeling
Keywords: نشانه Photoafinity; Photoaffinity labeling; Diazirine; Fluorogenic; ATP; Glutamate dehydrogenase
Photoaffinity labeling studies of the carbohydrate-binding proteins with different affinities
Keywords: نشانه Photoafinity; Photoaffinity labeling; Photoaffinity probes; Carbohydrate-binding proteins; Carbohydrate-protein interaction; Lectin;
Synthesis of photoreactive ivermectin B1a derivatives and their actions on Haemonchus and Bombyx glutamate-gated chloride channels
Keywords: نشانه Photoafinity; AVM; avermectin; DCC; dicyclohexylcarbodiimide; DIPEA; N,N-diisopropylethylamine; DMAP; 4-(dimethylamino)pyridine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; EDC; 1-ethyl-3-(3-dimethylamino-propyl)carbodiimide; GABA; γ-aminobutyric acid; GABAC
The development of new molecular tools containing a chemically synthesized carbohydrate ligand for the elucidation of carbohydrate roles via photoaffinity labeling: Carbohydrate–protein interactions are affected by the structures of the glycosidic bonds a
Keywords: نشانه Photoafinity; Carbohydrate–lectin interactions; Oligosaccharide synthesis; Molecular tool; Photoaffinity labeling; Different glycosidic bonds
Interaction of Ddc1 and RPA with single-stranded/double-stranded DNA junctions in yeast whole cell extracts: Proteolytic degradation of the large subunit of replication protein A in ddc1Î strains
Keywords: نشانه Photoafinity; Double-stranded/single-stranded DNA junctions; Photoaffinity labeling; Ddc1 checkpoint protein; Replication protein A (RPA); Protein degradation; Proteasome;
Affinity-based fluorogenic labeling of ATP-binding proteins with sequential photoactivatable cross-linkers
Keywords: نشانه Photoafinity; Diazirine; Photoaffinity labeling; ATP; Coumarin; Cinnamate;
Direct demonstration of unique mode of natural peptide binding to the type 2 cholecystokinin receptor using photoaffinity labeling
Keywords: نشانه Photoafinity; Cholecystokinin; Type 2 cholecystokinin receptor; Ligand binding; Photoaffinity labeling; G protein-coupled receptors;
Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182
Keywords: نشانه Photoafinity; MAGI; multinuclear activation of a galactosidase indicator; Anti-HIV agents; PD 404182; Photoaffinity labeling; Pyrimidobenzothiazine;
Microwave-assisted synthesis of substituted fluorophenyl mono- and diazides by SNAr. A fast methodology to prepare photoaffinity labeling and crosslinking reagents
Keywords: نشانه Photoafinity; Fluoroarylazide; Microwave; Photoaffinity labeling; Diazides
Development of clickable active site-directed photoaffinity probes for γ-secretase
Keywords: نشانه Photoafinity; γ-Secretase; Photoaffinity labeling; Click chemistry; Clickable photoprobe; Alzheimer’s disease
Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2
Keywords: نشانه Photoafinity; Benzamides; HDAC 1 and 2; Time-dependent inhibition; Photoaffinity labeling; Diazides
Tandem photoaffinity labeling-bioorthogonal conjugation in medicinal chemistry
Keywords: نشانه Photoafinity; Bioorthogonal conjugation; Click chemistry; Ligand design; Medicinal chemistry; Photoaffinity labeling;
Diazirine based photoaffinity labeling
Keywords: نشانه Photoafinity; Diazirine; Photoaffinity labeling; Photochemistry; Chemical proteomics; Protein profiling;
Synthesis and characterization of photoaffinity probe of acetogenin, a strong inhibitor of mitochondrial complex I
Keywords: نشانه Photoafinity; Acetogenins; Photoaffinity labeling; Radioiodination; Mitochondrial complex I; Respiratory enzyme;
The effect of structural differences in the reducing terminus of sugars on the binding affinity of carbohydrates and proteins analyzed using photoaffinity labeling
Keywords: نشانه Photoafinity; Photoaffinity labeling; Molecular tools; Carbohydrate–protein interaction; Atomic force microscopy (AFM)
Photo-DHEA—A functional photoreactive dehydroepiandrosterone (DHEA) analog
Keywords: نشانه Photoafinity; DHEA; Dehydroepiandrosterone; Photoaffinity labeling; Receptor; G protein-coupled receptor
Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology
Keywords: نشانه Photoafinity; Boc; tert-butyloxycarbonyl; Br-BC5; [(E)-(3-((4-bromo-2-methylbut-2-enyloxy)methyl)phenyl)-(phenyl)methanone]; Br-BC10; [(3-(((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dienyloxy)methyl)-phenyl)(phenyl)methanone]; t-Bu; tert-butyl; CLEAR; cross-linked ethoxylat
A versatile access to new halogenated 7-azidocoumarins for photoaffinity labeling: Synthesis and photophysical properties
Keywords: نشانه Photoafinity; Aryl azides; Coumarins; Pd-catalyzed amination; Photoaffinity labeling; Photochemistry; Pro-fluorescence
Azido-iodo-N-benzyl derivatives of threo-methylphenidate (Ritalin, Concerta): Rational design, synthesis, pharmacological evaluation, and dopamine transporter photoaffinity labeling
Keywords: نشانه Photoafinity; Methylphenidate; Ritalin; Concerta; Photoaffinity labeling; Dopamine transporter; Cocaine; Attention-deficit hyperactivity disorder;
Identification by photoaffinity labeling of the extracellular N-terminal domain of PAC1 receptor as the major binding site for PACAP
Keywords: نشانه Photoafinity; G protein-coupled receptors; Pituitary adenylate cyclase-activating polypeptide; PAC1 receptor; Binding sites; Two-domain model; Photoaffinity labeling; Bip; biphenylalanine; Bpa; p-benzoyl-phenylalanine; CHO; Chinese hamster ovary; CNBr; cyanogen bromide
Photoaffinity labeling of Ras converting enzyme using peptide substrates that incorporate benzoylphenylalanine (Bpa) residues: Improved labeling and structural implications
Keywords: نشانه Photoafinity; Photoaffinity labeling; Benzophenone; Bpa; Rce1; Prenyl protease; Protein prenylation; CAAX processing; Farnesyl;
Ddc1 checkpoint protein and DNA polymerase É interact with nick-containing DNA repair intermediate in cell free extracts of Saccharomyces cerevisiae
Keywords: نشانه Photoafinity; DNA polymerase É; Ddc1 checkpoint protein; DNA single-strand breaks; Photoaffinity labeling;
A diazirine-based photoaffinity etoposide probe for labeling topoisomerase II
Keywords: نشانه Photoafinity; Photoaffinity labeling; Etoposide; Topoisomerase II; Diazirine
Photoaffinity labeling of Ras converting enzyme 1 (Rce1p) using a benzophenone-containing peptide substrate
Keywords: نشانه Photoafinity; Abz; 2-aminobenzoyl; C5BP; 3-methylbenzophenone prenyl ether; CLEAR; crosslinked ethoxylate acrylate resin; Dde; 1-(4,4-dimethyl-2,6-dioxocyclohexylidene) ethyl; DI; deionized; DIEA; diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfox
Why do p-nitro-substituted aryl azides provide unintended dark reactions with proteins?
Keywords: نشانه Photoafinity; Aryl azide; Photoaffinity labeling; Long-lived intermediate; Aromatic nitroso compound; Aromatic hydroxylamine; Modified tryptophan
Stereo-controlled synthesis of novel photoreactive γ-secretase inhibitors
Keywords: نشانه Photoafinity; Aspartyl proteases; Alzheimer disease; Photoaffinity labeling; Secretase; Dipeptide isostere
A novel photoaffinity ligand for the dopamine transporter based on pyrovalerone
Keywords: نشانه Photoafinity; Pyrovalerone; Photoaffinity labeling; Dopamine transporter; Cocaine
Exploring the binding site of acetogenin in the ND1 subunit of bovine mitochondrial complex I
Keywords: نشانه Photoafinity; Mitochondrial complex I; Acetogenin; Respiratory inhibitor; Photoaffinity labeling; ND1 subunit
Facile synthesis of diazido-functionalized biaryl compounds as radioisotope-free photoaffinity probes by Suzuki–Miyaura coupling
Keywords: نشانه Photoafinity; Photoaffinity labeling; Radioisotope-free; Suzuki–Miyaura coupling; Dantrolene
Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site
Keywords: نشانه Photoafinity; CXCR4; T140; GPCR; Photoaffinity labeling; Molecular modeling; Ligand-binding pocket
A versatile photoactivatable probe designed to label the diphosphate binding site of farnesyl diphosphate utilizing enzymes
Keywords: نشانه Photoafinity; Benzophenone; Farnesyltransferase; Farnesyl diphosphate synthase; Sesquiterpene cyclase; Photoaffinity labeling
Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes
Keywords: نشانه Photoafinity; HIV-1 integrase inhibitors; Diketo acids; Photoaffinity labeling; Photoprobes
Demonstration of direct binding of cIAP1 degradation-promoting bestatin analogs to BIR3 domain: Synthesis and application of fluorescent bestatin ester analogs
Keywords: نشانه Photoafinity; Bestatin; cIAP1; BIR3 domain; Fluorescence polarization; Photoaffinity labeling
Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species
Keywords: نشانه Photoafinity; Parthenium argentatum; Guayule; Ficus elastica; Hevea brasiliensis; Photoaffinity labeling; Benzophenone; Allylic pyrophosphate; Farnesyl pyrophosphate; Rubber transferase; Cis-prenyltransferase;
Structural basis of cholecystokinin receptor binding and regulation
Keywords: نشانه Photoafinity; Cholecystokinin; Gastrin; Photoaffinity labeling; GPCR; Molecular modelingBpa, p-benzoyl-l-phenylalanine; CCK, cholecystokinin; ECL, extracellular loop; G protein, guanine nucleotide-binding protein; GPCR, G protein-coupled receptor; pNO2-Phe, p-nitro-phe
Photo-labeling of C60 with 3-trifluoromethyl-3-phenyldiazirine
Keywords: نشانه Photoafinity; C60; 3-Trifluoromethyl-3-phenyldiazirine; Carbene; Photoaffinity labeling;
Cloning, purification, and nucleotide-binding traits of the catalytic subunit A of the V1VO ATPase from Aedes albopictus
Keywords: نشانه Photoafinity; Vacuolar-type ATPase; V1VO ATPase; V1 ATPase; Subunit A; Photoaffinity labeling; Fluorescence correlation spectroscopy; Mosquito;
Mapping of cytochrome P450 2B4 substrate binding sites by photolabile probe 3-azidiamantane: Identification of putative substrate access regions
Keywords: نشانه Photoafinity; CYP2B4; Photoaffinity labeling; Diamantane; Access channel; Enzyme structure
A photoaffinity, non-steroidal, ecdysone agonist, bisacylhydrazine compound, RH-131039: Characterization of binding and functional activity
Keywords: نشانه Photoafinity; Photoaffinity labeling; Limited proteolysis; Ecdysteroid receptor; Non-steroidal ecdysone agonist; Photoaffinity ecdysone agonist; Dipteran EcR; Lepidopteran EcR
Catalytic implications of the higher plant ADP-glucose pyrophosphorylase large subunit
Keywords: نشانه Photoafinity; Potato tuber AGPase; ADP-glucose pyrophosphorylase; Large subunit; Allosteric regulation; Catalytic roles; In vitro mutagenesis; Photoaffinity labeling;
Characterization of the Munc13-calmodulin interaction by photoaffinity labeling
Keywords: نشانه Photoafinity; Vesicle priming; Munc13; Calmodulin; Short-term plasticity; Ca2+ sensitivity; Photoaffinity labeling