Keywords: محلول نمک فیزیولوژیکی; EFS; electrical field stimulation; FOV; field of view; LTCC; L-type Ca2+ channel; NCX; Na+/Ca2+ exchanger; PSS; physiological salt solution; SR; sarcoplasmic reticulum; ROI; region of interest; RyR; ryanodine receptor; Pulmonary vein; Pulmonary vein cardi
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Keywords: محلول نمک فیزیولوژیکی; ECG; Electrocardiogram; PSS; Physiological salt solution; SGOT; Serum glutamic oxaloacetic transaminase; SGPT; Serum glutamic-pyruvic transaminase; Aconite; Acute protection; Borax; Cardiac activity; Neuro-muscular activity; Sub-acute protection;
Keywords: محلول نمک فیزیولوژیکی; Mexiletine; Antiarrhythmics; P-glycoprotein; Inotropism; MW-assisted synthesis; CNS; central nervous system; DMEM; Dulbecco's modified eagle's medium; GPILSM; guinea pig ileum longitudinal smooth muscle; HepG2; human hepatocellular liver carcinoma cel
Keywords: محلول نمک فیزیولوژیکی; prostate; prostatic hyperplasia; muscle; smooth; calcium channels; interstitial cells of Cajal; α-SMA; α-smooth muscle actin; AMP; peak amplitude; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; ICC; interstitial cell of Cajal; [K+]o; ext
Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay
Keywords: محلول نمک فیزیولوژیکی; Calcium signalling; Store-operated calcium entry (SOCE); Pharmacological inhibitors; Pharmacophore modelling; Orai1; Breast cancer; AFU; arbitrary fluorescence units; CPA; cyclopiazonic acid; [Ca2+]CYT; cytosolic free Ca2+; ER; endoplasmic reticulum; FLIP
Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7
Keywords: محلول نمک فیزیولوژیکی; BSA; bovine serum albumin; CHOL; cholesterol; C1P; ceramide-1-phosphate; FLIPRTETRA; fluorescent imaging plate reader; GMT; gating modifier toxin; HBS; HEPES buffered saline; ICK; inhibitory cystine knot; LUV; large unilamellar vesicle; hNaV; human voltag
Reactive oxygen species facilitate the EDH response in arterioles by potentiating intracellular endothelial Ca2+ release
Keywords: محلول نمک فیزیولوژیکی; AACOCF3; arachidonyl trifluoromethyl ketone; AUDA; 12-(3-adamantan-1-yl-ureido)dodecanoic acid; CP85; Na-1-ethylsulfoxide-2-methyl-3-hyroxypyridin-4-one; CP94; 1,2-diethyl-3-hyroxypyridin-4-one; CPA; Cyclopiazonic Acid; DFO; Desferrioxamine; EC; endotheli
Equol increases cerebral blood flow in rats via activation of large-conductance Ca2+-activated K+ channels in vascular smooth muscle cells
Keywords: محلول نمک فیزیولوژیکی; ACh; acetylcholine; 4-AP; 4-aminopyridine; ANOVA; analysis of variance; BaCl2; barium chloride; BK; large-conductance, voltage- and Ca2+ -activated K+ channel; BSA; bovine serum albumin; CASMCs; cerebral artery smooth muscle cells; DBP; diastolic blood pr
Cardiovascular pharmacologyPannexin-1 channels do not regulate α1-adrenoceptor-mediated vasoconstriction in resistance arteries
Keywords: محلول نمک فیزیولوژیکی; Emax; maximum possible effect for the agonist; KPSS; isotonic potassium physiological salt solution; L-NAME; NÏ-nitro-l-arginine methyl ester hydrochloride; NO; nitric oxide; NOS; nitric oxide synthase; PSS; physiological salt solution; Px1; pannexin-1;
Contrasting cardiovascular properties of the µ-opioid agonists morphine and methadone in the rat
Keywords: محلول نمک فیزیولوژیکی; ECG; electrocardiogram; HR; heart rate; KPSS; isotonic potassium physiological salt solution; MAP; mean arterial pressure; NO; nitric oxide; NOS; nitric oxide synthase; pEC50; the negative log10 of agonist concentration that caused 50% of the maximum resp
Vasodilatory effects of the selective GPER agonist G-1 is maximal in arteries of postmenopausal women
Keywords: محلول نمک فیزیولوژیکی; ACh; acetylcholine; BK; bradykinin; CVD; cardiovascular diseases; DAB; 3,3â²-diaminobenzidine; DMEM; Dulbecco's modified Eagle's medium; eNOS; endothelial nitric oxide synthase; ERs; estrogen receptor; ERα; estrogen receptor alpha; ERβ; estrogen recept
Valproic acid increases NO production via the SH-PTP1-CDK5-eNOS-Ser116 signaling cascade in endothelial cells and mice
Keywords: محلول نمک فیزیولوژیکی; eNOS; endothelial nitric oxide synthase; CDK5; cyclin-dependent kinase 5; JNK; c-Jun N-terminal kinase; Abl; Abelson kinase; SH-PTP; SH2 domain-containing protein tyrosine phosphatase; VPA; valproic acid; HDAC; histone deacetylase; HUVEC; human umbilical
Reduced angiotensin II levels cause generalized vascular dysfunction via oxidant stress in hamster cheek pouch arterioles
Keywords: محلول نمک فیزیولوژیکی; ACE; angiotensin converting enzyme; ACh; acetylcholine; ANG II; angiotensin II; ARB; angiotensin receptor blocker; AT1; angiotensin II type 1 receptor; cGMP; cyclic guanosine monophosphate; Cu/Zn SOD; copper zinc (intracellular) superoxide dismutase; DHE;
Erythropoietin has a restorative effect on the contractility of arteries following experimental hypoxia
Keywords: محلول نمک فیزیولوژیکی; Myograph; Microcirculation; Obesity; ACh; acetylcholine; BMI; body mass index; CKD; chronic kidney disease; eNOS; endothelial nitric oxide synthase; EPO; erythropoietin; KPSS; high potassium physiological salt solution; LDL; low density lipoproteins; l-NN
Large conductance Ca2+-activated K+ channels modulate endothelial cell outward currents and nitric oxide release in the intact rat superior mesenteric artery
Keywords: محلول نمک فیزیولوژیکی; CBX; carbenoxolone; Cin; input capacitance; EC; endothelial cells; MEGJ; myoendothelial gap junctions; PSS; physiological salt solution; Rin; input resistance; VSMC; vascular smooth muscle cells; Endothelial cell; Large conductance Ca2+-activated K+ chann
The origin of the skewed amplitude distribution of spontaneous excitatory junction potentials in poorly coupled smooth muscle cells
Keywords: محلول نمک فیزیولوژیکی; calcium imaging; confocal microscopy; neurotransmission; smooth muscle; ATP; sEJP; α-SNAP; α-soluble N-ethylmaleimide-sensitive factor attachment protein; BAPTA-1 AM; 1,2-bis(o-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid-1 acetoxymethyl ester
Effects of the type of dietary fat on acetylcholine-evoked amylase secretion and calcium mobilization in isolated rat pancreatic acinar cells
Keywords: محلول نمک فیزیولوژیکی; ACh; acetylcholine; CCK-8; cholecystokinin-octapeptide; PSS; physiological salt solution; BSA; bovine serum albumin; LDH; lactate dehydrogenase; PMCA; plasma membrane calcium ATPase; SERCA; sarcoplasmic/endoplasmic reticulum calcium ATPase; IP3; inositol
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives
Keywords: محلول نمک فیزیولوژیکی; Muscarinic agonist; Subtype selectivity; Dioxolane derivative; Oxathiolane derivative; Binding studies; Functional studies; CHO; Chinese hamster ovary; hm1-hm5; human muscarinic subtypes; M1-M5; muscarinic subtypes; Ki; inhibitor equilibrium dissociat
Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone
Keywords: محلول نمک فیزیولوژیکی; apoptosis; glutamate receptors; regeneration; stem cells; degeneration; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; BDNF; brain-derived neurotrophic factor; CNM; basal, low insulin containing medium; CNPase; 2â²,3â²-cyclic nucleotide-3