دانلود مقالات ISI درباره Pka + ترجمه فارسی

Herbs to curb cyclic nucleotide phosphodiesterase and their potential role in Alzheimer's disease

Keywords: cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; AD; Alzheimer's disease; PDE; phosphodiesterases; Aβ; amyloid beta; NFTs; neurofibrillary tangles; FAD; familial Alzheimer's disease; SAD; sporadic Alzheimer's disease; APP

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

Keywords: 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3′,5′-cyclic adenosine monophosphate;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin

Keywords: AKAP; A-kinase anchoring proteins; Bcl-2; B-cell lymphoma 2 anti-apoptotic protein; BSA; bovine serum albumin; C and R; catalytic and regulatory regions; cAMP; adenosine 3′,5′-cyclic monophosphate; Cav-1; caveolin-1; CREB; cAMP response element bindin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Presynaptic cell type-dependent regulation of GABAergic synaptic transmission by nitric oxide in rat insular cortex

Keywords: ACSF; artificial cerebrospinal fluid; BSA; bovine serum albumin; cGMP; cyclic guanosine monophosphate; CTA; conditioned taste aversion; DAB; 3-3′-diaminobenzidine; EGTA; ethylene glycol tetraacetic acid; FS; fast-spiking interneuron; GC; guanylyl cyclas

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy

Keywords: PDEs; phosphodiesterases; AKAP; A-kinase anchoring protein; cAMP; 3′,5′-cyclic monophosphate; Epac; exchange protein directly activated by cAMP; PKA; protein kinase A; PKC; protein kinase C; PKD; protein kinase D; UCR; upstream conserved region; β-AR

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y11 receptor in rat cardiac myofibroblasts

Keywords: [Ca2+]i; intracellular calcium; ADPRC; ADP-ribosylcyclase; ATP; adenosine 5′-triphosphate sodium salt; ATPγS; adenosine 5′-[γ-thio]triphosphate tetralithium salt; 2-APB; 2-aminoethoxydiphenylborane; BSA; bovine serum albumin; cADPR; cyclic adenosine

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Glutamatergic synapse protein composition of wild-type mice is sensitive to in utero MTHFR genotype and the timing of neonatal vigabatrin exposure

Keywords: AED; antiepileptic drugs; AMPA; a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CaMKII; Calcium/calmodulin-dependent kinase II; Dab1; Disabled-1; EPM; elevated plus maze; FMRP; Fragile X mental retardation 1 protein; GluR1; AMPA receptor subunit 1;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

The integrated role of ACh, ERK and mTOR in the mechanisms of hippocampal inhibitory avoidance memory

Keywords: 4E-BPs; 4E binding proteins; ACh; acetylcholine; AD; Alzheimer's Disease; APP; amyloid precursor protein; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CREB; cAMP response element-binding protein; DG; dentate gyrus; eEF1A; eukaryotic Elongation F

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

The Notch intracellular domain represses CRE-dependent transcription

Keywords: CREB; NICD; PKA; Alzheimer's disease; Memory;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

DFT study on the tautomerism of organic linker 1H-imidazole-4,5-tetrazole (HIT)

Keywords: Tautomerism; Imidazole; Tetrazole; NMR; Redox potential; pKa;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Heterodimerization of human orexin receptor 1 and kappa opioid receptor promotes protein kinase A/cAMP-response element binding protein signaling via a Gαs-mediated mechanism

Keywords: GPCR; G-protein-coupled receptor; OX1R; orexin (hypocretin) receptor 1; KOR; kappa opioid receptor; BRET; bioluminescence resonance energy transfer; FRET; fluorescence resonance energy transfer; CREB; cAMP-response element binding protein; PKA; protein ki

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2015 سفارش ترجمه

Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells

Keywords: AC; adenylyl cyclases; AKAR; A-kinase activity receptor 3; AP; action potential; β-AR; β-adrenergic receptor; CaMKII; Ca2 +/calmodulin-dependent protein kinase II; ISO; isoproterenol; M; membrane; PDE; phosphodiesterase; PKA; protein kinase A; PLB; pho

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium

Keywords: cAMP; cyclic adenosine monophosphate; Epac; cAMP-activated guanine nucleotide exchange factor; ERK; extracellular signal-regulated kinase; GLP-1R; glucagon-like peptide-1 receptor; GLUT-1/4; glucose transporter 1/4; PKA; protein kinase A; PLB; phospholamb

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2015 سفارش ترجمه

The adrenergic-regulated CRTC1 and CRTC2 phosphorylation and cellular distribution is independent of endogenous SIK1 in the male rat pinealocyte

Keywords: CREB-regulated transcription coactivators; Salt-inducible kinase; Pineal; Norepinephrine; AA-NAT; arylalkylamine-N-acetyltransferase; Cal-C; Calphostin C; CRE; cAMP response element; CREB; cAMP-response element binding protein; CRTC; cAMP-regulated transc

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications

Keywords: Ac; acetylated; AMPK; Adenosine Monophosphate-activated Protein Kinase; BrS; Brugada syndrome; CaMKII; Ca2 +/Calmodulin-dependent Kinase II; INa; cardiac voltage-gated Na+ current; INaL; cardiac voltage-gated late Na+ current; LQTS; long QT syndrome; Me;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology

Keywords: AAV; adeno-associated virus; AON; antisense oligonucleotide; bp; base pair; Ca2+;  calcium; CaMKII; Ca2+/calmodulin-dependent kinase II; Chr; chromosome; CK2; casein kinase 2; CMH4; hypertrophic cardiomyopathy, locus 4; cMyBP-C; cardiac myosin-binding pr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Regulatory function of the C-terminal segment of guanylate cyclase-activating protein 2

Keywords: CNDPK; cyclic nucleotide-dependent protein kinase; GCAP; guanylate cyclase-activating protein; GR; GCAP2-recoverin C-terminal chimeric protein; GRK1; G-protein-coupled receptor kinase 1 synonymous to rhodopsin kinase; GST-N-RK; fusion protein of glutathio

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Synapse-specific compartmentalization of signaling cascades for LTP induction in CA3 interneurons

Keywords: AC; adenylyl cyclase; ACSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; CaMKII; calcium/calmodulin-dependent protein kinase II; CI-AMPAR; calcium-impermeable AMPAR; CP-AMPAR; calcium permeable AMPAR; DCG-IV; (2S,2′R,3′R)-2-(2′,3′-

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2015 سفارش ترجمه

β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis

Keywords: WNT; β-Catenin; E-Cadherin; Liver Fibrosis; NASH; HCC; Liver Tumors; AJ; adherens junction; APC; adenomatous polyposis coli gene product; FNH; focal nodular hyperplasia; FOXO; forkhead box protein O; GS; glutathione synthetase; GSK3β; glycogen synthase

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2015 سفارش ترجمه

Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes

Keywords: NF1; neurofibromatosis type 1; MEN2; Multiple Endocrine Neoplasia type 2; MTC; medullary thyroid carcinoma; CCH; C-cell hyperplasia; C-cells; parafollicular cells; CT; calcitonin; PKA; protein kinase A; Neurofibromatosis type 1; NF1 gene; RET gene; Thyroi

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Development of ratiometric fluorescent pH sensors based on chromenoquinoline derivatives with tunable pKa values for bioimaging

Keywords: Chromenoquinoline; pH; Ratiometric; pKa; Sensor;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

The effect of pKa on pyrimidine/pyridine-derived histamine H4 ligands

Keywords: Histamine H4; H4; pKa; Pyrimidine; Pyridine; Aminopyrimidine;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Short communicationNMDA receptor activation and PKC but not PKA lead to the modification of the long-term potentiation in the insular cortex induced by conditioned taste aversion: Differential role of kinases in metaplasticity

Keywords: LTP; CTA; PKA; PKC; NMDAR; Metaplasticity;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Faster photodegradation rate and higher dioxin yield of triclosan induced by cationic surfactant CTAB

Keywords: Triclosan; Surfactants; CTAB; pKa; Anionic speciation, Dioxin yield;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondria: A kinase anchoring protein 1, a signaling platform for mitochondrial form and function

Keywords: AKAP; A kinase anchoring protein; BAD; Bcl-2-associated death promoter; cAMP; cyclic AMP; CaN; calcineurin; Casp; caspase; Drp1; dynamin-related protein 1; Fo-f; ATP synthase Fo complex; HIF-1a; hypoxia induced factor 1a; KH; K homology; LPL; lipoprotein

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

The novel transferrin E592A variant impairs the diagnostics of congenital disorders of glycosylation

Keywords: CDG; congenital disorders of glycosylation; Tf; transferrin; CDT; carbohydrate-deficient transferrin; HPLC; high-performance liquid chromatography; IEF; isoelectric focusing; ESI-TOF MS; electrospray ionization time of flight mass spectrometry; pKa; acid

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Determination of pKavalues of a triptolide derivative and its impurities by pressure-assisted capillary electrophoresis

Keywords: Capillary electrophoresis; External pressure; pKa; Triptolide derivative; Impurities; Potentiometric titration;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of TNF-α converting enzyme promotes adipose tissue inflammation and fibrosis induced by high fat diet

Keywords: ADAM; a disintegrin and metalloproteinase; CD; control diet; ELISA; enzyme-linked immunosorbent assay; HE; hematoxylin and eosin; HFD; high fat diet; MCP-1; macrophage chemotactic protein-1; PKA; protein kinase A; PMA; phorbol myristate acetate; SD; stand

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

RFP tags for labeling secretory pathway proteins

Keywords: Red fluorescent proteins; Artificial puncta; Kd; Evaluation method; pKa;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

The complex understanding of Annexin A1 phosphorylation

Keywords: Annexin A1; ANXA1; Phosphorylation; PKC; EGFR; PKA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

PSII manganese cluster: Protonation of W2, O5, O4 and His337 in the S1 state explored by combined quantum chemical and electrostatic energy computations

Keywords: PSII; Mn-cluster; Protonation of the OEC; Redox states; pKa;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Glutamate transporter type 3 regulates mouse hippocampal GluR1 trafficking

Keywords: ACSF; artificial cerebrospinal fluid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; DMSO; dimethyl sulfoxide; EAAT; excitatory amino acid transporter; PKA; protein kinase A; PP2A; protein phosphatase 2A; α-Amino-3-hydroxy-5-methy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of adipogenesis and leptin production in 3T3-L1 adipocytes by a derivative of meridianin C

Keywords: Meridianin C derivative; Adipogenesis; PPAR-γ; C/EBP-α; STAT-3/5; cAMP; adenosine 3′,5′-cyclic monophosphate; C/EBP-α; CCAAT/enhancer-binding protein-α; ERK-1/2; extracellular signal-regulated protein kinase-1/2; FAS; fatty acid synthase; JAK-2; j

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The glucagon-like peptide 1 receptor agonist enhances intrinsic peroxisome proliferator-activated receptor γ activity in endothelial cells

Keywords: GLP-1; glucagon-like peptide-1; HUVECs; human umbilical vein endothelial cells; PKA; protein kinase A; IRS-1; insulin receptor substrate-1; JNK; c-Jun N-terminal kinase; NF-κB; nuclear factor-kappa B; TNFα; tumor necrosis factor α; ICAM-1; intercellula

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

cNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects

Keywords: AM; acetoxymethylester; cAMP; adenosine 3′,5′-cyclic monophosphate; cGMP; guanosine 3′,5′-cyclic monophosphate; cCMP; cytidine 3′,5′-cyclic monophosphate; cNMP; 3′,5′-cyclic nucleoside monophosphate; cUMP; uridine 3′,5′-cyclic monophos

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

PDE7A1 hydrolyzes cCMP

Keywords: A549; human lung carcinoma cell line; AMP; adenosine 5′-monophosphate; cAMP; adenosine 3′,5′-cyclic monophosphate; B103; rat neuroblastoma cells; CMP; cytidine 5′-monophosphate; cCMP; cytidine 3′,5′-cyclic monophosphate; CyaA; Bordetella pertu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Cyclopropenimine as a hydrogen bond acceptor-towards the strongest non-phosphorus superbases

Keywords: Organic superbase; Hydrogen bonds; DFT calculations; Proton affinity; pKa;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Dissociation ability of humic acids: Spectroscopic determination of pKa and comparison with multi-step mechanism

Keywords: Humic acids; pKa; Dissociation; Functional group; Solubility;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Centrally formed acetaldehyde mediates ethanol-induced brain PKA activation

Keywords: Acetaldehyde; PKA; Ethanol;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Reprint of PSII Manganese Cluster: Protonation of W2, O5, O4 and His337 in the S1 state explored by combined quantum chemical and electrostatic energy computations

Keywords: PSII; Mn-cluster; Protonation of the OEC; Redox states; pKa;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The role of cAMP dependent protein kinase in modulating spontaneous intracellular Ca2+ waves in interstitial cells of Cajal from the rabbit urethra

Keywords: Urethra; ICC; Ca2+ waves; PKA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms that underlie the internalization and extracellular signal regulated kinase 1/2 activation by PKR2 receptor

Keywords: AT1AR; angiotensin type 1A receptor; ConA; Concanavalin A; DN-GRK; dominant-negative G-protein-coupled receptor kinase 2; EGFP; enhanced green fluorescent protein; ERK; extracellular signal regulated kinase; GPCR; G-protein-coupled receptors; GRK; GPCR ki

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Melatonin counteracts BMP-6 regulation of steroidogenesis by rat granulosa cells

Keywords: ALK; activin receptor-like kinase; ActRI; activin type-I receptor; ActRII; activin type-II receptor; BMP; bone morphogenetic protein; BMPRI; BMP type-I receptor; BMPRII; BMP type-II receptor; FSH; follicle-stimulating hormone; FSHR; FSH receptor; GDF; gro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic reticulum-mitochondria coupling

Keywords: GLP-1; VSMC; Mitochondrial metabolism; ER-mitochondria coupling; PKA; Mitofusin-2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

An interplay between 2 signaling pathways: Melatonin-cAMP and IP3-Ca2+ signaling pathways control intraerythrocytic development of the malaria parasite Plasmodium falciparum

Keywords: 2-APB; 2-aminoethyl diphenylborinate; IP3; inositol 1,4,5-trisphosphate; LZ; luzindole; PLC; phospholipase C; AC; adenylyl cyclase; PKA; protein kinase A; MDL; MDL12330A; IBMX; 3-isobutyl-1-methylxanthine; Plasmodium falciparum; Signaling pathway; Ca2+ os

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacological options to protect the aged heart from ischemia and reperfusion injury by targeting the PKA-BKCa signaling pathway

Keywords: BKCa; large-conductance calcium-sensitive potassium channel; NS1619; 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one; PKA; protein kinase A; Cx43; connexin43; TIM23; translocase of the inner membrane 23 kDa;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Enhancement of the p38 MAPK and PKA signaling pathways is associated with the pro-melanogenic activity of Interleukin 33 in primary melanocytes

Keywords: IL-33; NHEM; Melanogenesis; p38 MAPK; PKA; CREB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of PKA, PKC, CAMK-II and MEK1/2 in the acute antidepressant-like effect of creatine in mice

Keywords: CaMKII; Ca2+/calmodulin protein kinase II; CREB; cyclic adenosine monophosphate response element binding protein; ERK1/2; extracellular signal-regulated kinases; MEK1/2; mitogen-activated protein kinase kinase 1/2; PKA; protein kinase A; PKC; protein kina

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The differential proliferative response of fetal and adult human skin fibroblasts to TGF-β is retained when cultured in the presence of fibronectin or collagen

Keywords: TGF-β; Human skin fibroblast; Fetal; Adult; Fibronectin; Collagen gel; Proliferation; Smad; ERK; PKA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A transitional hydrolase to glycosynthase mutant by Glu to Asp substitution at the catalytic nucleophile in a retaining glycosidase

Keywords: Glycosynthase; β-Glucanase; Bacillus licheniformis; Hydrolase; β-1,3-1,4-Glucans; pKa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه