دانلود مقالات ISI درباره Pka + ترجمه فارسی

Synthesis and evaluation of heteroaryl substituted diazaspirocycles as scaffolds to probe the ATP-binding site of protein kinases

Keywords: AGC; protein kinases A G and C; ATP; adenosine triphosphate; 9-BBN; 9-borabicyclo[3.1.1.]nonane Boc tert-butyloxycarbonyl; CAMK; calcium/calmodulin-dependent kinases; Cbz; benzyloxycarbonyl; DFG; aspartate-phenylalanine-glycine sequence; DIBAL-H; diis

دانلود رایگان متن کامل مقاله ISI 70 صفحه سال انتشار : 2013 سفارش ترجمه

Photo-induced reversible proton dissociation of spirobenzopyran in aqueous systems

Keywords: Spirobenzopyran; Proton dissociation; pKa; Photoisomerization; Aqueous polymer solution

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A theoretical study of factors affecting corrosion in supercritical water reaction vessels

Keywords: Supercritical; Water; pKa; pKb; pKW; Corrosion

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Dietary antioxidants prevent alcohol-induced ciliary dysfunction

Keywords: Alcohol; Ciliary dysfunction; Nitric oxide; PKA; PKG; N-acetylcysteine; Procysteine; Ciliary beat frequency

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Anthocyanins attenuate body weight gain via modulating neuropeptide Y and GABAB1 receptor in rats hypothalamus

Keywords: Obesity; Anthocyanins; Neuropeptide Y; GABAB1 receptor; p-CREB; PKA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of passive samplers with neutral or ion-exchange polymer coatings to determine freely dissolved concentrations of the basic surfactant lauryl diethanolamine: Measurements of acid dissociation constant and organic carbon–water sorption coefficie

Keywords: SPME-fibers; Cationic surfactant; Cation-exchange; pKa; Sorption; Humic acid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Dynamic alterations in the expression and localization of ACTL7a during capacitation in mouse spermatozoa

Keywords: ACTL7a; capacitation; PKA; PKC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Involvement of spinal PKA/CREB signaling pathway in the development of bone cancer pain

Keywords: bone cancer pain; PKA; CREB; signaling pathway

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Interaction of Ubinuclein-1, a nuclear and adhesion junction protein, with the 14-3-3 epsilon protein in epithelial cells: Implication of the PKA pathway

Keywords: TJ, tight junction; NACos, Nuclear and Adhesion junction Complex components; Ubn-1, Ubinuclein-1; PKA, cAMP-dependent protein kinase AEpithelial; Tight junction; Signaling pathway; PKA; 14-3-3ɛ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase

Keywords: GIRK1; GIRK4; PKA; cAMP; Heterologous facilitation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G

Keywords: AGS; activator of G protein-signaling; cAMP; cyclic adenosine monophosphate; CTD; carboxy-terminal domain; DMEM; Dulbecco's modified Eagle's medium; EMEM; Eagle's minimum essential medium; Epac; exchange protein activated by cAMP; ERK; extracellular signa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Temperature and functional plasticity of L-type Ca2+ channels in Drosophila

Keywords: LTCC, L-type calcium channels; BWM, body-wall muscleL-type Ca2+ channels; PKA; Drosophila; Temperature; Facilitation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Amino acid derived quinazolines as Rock/PKA inhibitors

Keywords: Rock; PKA; Quinazoline; Kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

PKA: Lessons learned after twenty years

Keywords: Protein kinase; PKA; Hydrophobic spine

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Physicochemical characterization and in vitro permeation of an indirubin derivative

Keywords: Indirubin; E804; Ionization constant; Lipophilicity; pKa; log P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Quantification of protonation in organic solvents using solution NMR spectroscopy: Implication in salt formation

Keywords: NMR; Chemical shift changes; Protonation; pKa; Salt formation; Counterion; Solvent effect

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacokinetic drivers of toxicity for basic molecules: Strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor

Keywords: pKa; Vd; Kinase inhibitor; Met; Lysosomes; Phosphatidylserine; Basic amines; Phospholipidosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Quercetin inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex

Keywords: Quercetin; Glutamate release; Cerebrocortical nerve terminals; Voltage-dependent Ca2+ channels; PKC; PKA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Determination of acidity constants by the capillary electrophoresis internal standard method. IV. Polyprotic compounds

Keywords: pKa; Acidity constant; Capillary electrophoresis; Internal standard; High throughput method; Polyprotic compounds

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Determination of acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection

Keywords: Thiol; Catalytic cysteine; pKa; Nucleophilicity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Glycogenic activity of R6, a protein phosphatase 1 regulatory subunit, is modulated by the laforin-malin complex

Keywords: AMPK; AMP-activated protein kinase; GAD; Gal4 activating domain; GS; glycogen synthase; LD; Lafora disease; PKA; protein kinase A; Ph; glycogen phosphorylase.; Laforin; Malin; Lafora disease; Protein phosphatase type 1; Glycogen regulation; PPP1R3D;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking

Keywords: Chronic obstructive pulmonary disease; acute lung injury; endothelial barrier; prostaglandins; vascular leakage; neutrophil trafficking; cAMP; Cyclic adenosine monophosphate; ECIS; Electric Cell-substrate Impedance Sensing system; EP; E-type prostanoid; F

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

CB1 cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells

Keywords: 2-AG; 2-arachidonoylglycerol; BSA; bovine serum albumin; CB1; CB1 cannabinoid receptor; Csk; C-terminal Src kinase; DAGL; diacylglycerol lipase; DTT; dithiothreitol; ECM; extracellular matrix; ERK1/2; extracellular signal-regulated kinases 1 and 2; EGFR;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibitors of Bacillus anthracis edema factor

Keywords: Adenylyl cyclase; Calmodulin; Edema factor; Fluorescence spectroscopy; (M)ANT-nucleotides; Molecular modeling; ANT; anthraniloyl; AC; adenylyl cyclase; ACD; adenylyl cyclase domain; EF; edema factor AC toxin from Bacillus anthracis; CaM; calmodulin; FRET;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Novel N-methylsulfonamide and retro-N-methylsulfonamide derivatives as 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) inhibitors with good ADME-related physicochemical parameters

Keywords: 17β-Hydroxysteroid dehydrogenase type 2; Enzyme inhibition; Osteoporosis; N-Methylsulfonamide derivatives; Retro-N-methylsulfonamide derivatives; Structure–activity relationship; Structure–property relationship; ADME properties; pKa; Log P; Aqueous solubi

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Differential striatal spine pathology in Parkinson's disease and cocaine addiction: A key role of dopamine?

Keywords: 6-OHDA; 6-hydroxydopamine; CaM; Calmodulin; cAMP; cyclic AMP; CaN; Calcineurin; Cdk5; cyclin-dependent kinase 5; DA; dopamine; GP; globus pallidus; MEF2; myocyte enhancer factor 2; MSNs; medium spiny neurons; NAc; nucleus accumbens; PD; Parkinson's dise

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Endogenous opiates and behavior: 2012

Keywords: Ach; acetylcholine; ACTH; adrenocorticotrophic hormone; ANG; angiotensin; ATP; adenosine triphosphate; BAM22; bovine adrenal medulla 22; BDNF; brain-derived neurotrophic factor; BEND; beta-endorphin; BFNA; beta-funaltrexamine; BNST; bed nucleus of the str

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2013 سفارش ترجمه

Preferential solvation of perfluorooctanoic acid (PFOA) by methanol in methanol–water mixtures: A potential overestimation of the dissociation constant of PFOA using a Yasuda–Shedlovsky plot

Keywords: Preferential solvation; Perfluorooctanoic acid; PFOA; pKa; Yasuda–Shedlovsky plot

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Neuronal and intracellular signaling pathways mediating GLP-1 energy balance and glycemic effects

Keywords: Leptin; GLP-1; NTS; Hypothalamus; Pancreas; Insulin; PKA; AMPK; MAPK; ERK; CREB; Food intake; Obesity;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Insights into the region responding to ΔpH change in major light harvesting complex

Keywords: Trans-thylakoid ΔpH; pKa; Non-photochemical quenching

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Protein kinase A phosphorylates Down syndrome critical region 1 (RCAN1)

Keywords: RCAN1/DSCR1/Adapt78; Calcineurin; PKA; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Phospholamban mutants compete with wild type for SERCA binding in living cells

Keywords: CFP; cyan fluorescent protein; FRET; fluorescence resonance energy transfer; Kd; dissociation constant; LOF; loss of function; PKA; protein kinase A; PLB; phospholamban; PLBM; PLB mutant; SDS; sodium dodecyl-sulfate; SERCA; sarco-endoplasmic reticulum Ca2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

An ATP analog-sensitive version of the tomato cell death suppressor protein kinase Adi3 for use in substrate identification

Keywords: Adi3; AvrPto-dependent Pto-interacting protein 3; CDK2; cyclin-dependent kinase 2; Gal83; galactose-specific gene 83; MBP; maltose binding protein; NDPK; nucleoside diphosphate kinase; PCD; programmed cell death; PKA; protein kinase A (or cAMP-dependent p

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Histaminergic effects on the frequency of repetitive spike firing in rat insular cortex

Keywords: ACSF; artificial cerebrospinal fluid; AHP; afterhyperpolarization; cAMP; cyclic-3′,5′-adenosine monophosphate; f/I; a plot of the number of spikes versus the amplitude of injected current; IC; insular cortex; PKA; protein kinase A; RAMH; R-α-methylhi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Nociceptin is upregulated by FSH signaling in Sertoli cells in murine testes

Keywords: Nociceptin; FSH; PKA; CREB; Signal transduction; Sertoli cells

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

TPCK inhibits AGC kinases by direct activation loop adduction at phenylalanine-directed cysteine residues

Keywords: TPCK; N-alpha-tosyl-l-phenylalanyl chloromethyl ketone; PDK1; 3-phosphoinositide dependent protein kinase-1; AGC; related to protein kinase A, protein kinase G and protein kinase C; RSK; ribosomal S6 kinase; S6K; S6 kinase; PKA; protein kinase A; ERK; ext

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10

Keywords: Tau; Alternative splicing; 9G8; PKA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The regulatory tandem domains of human phosphodiesterases 1 and 4 regulate a cyanobacterial adenylyl cyclase

Keywords: hPDE; human phosphodiesterase; CyaB1 AC; cyanobacterial adenylyl cyclase from Anabaena sp.; PKA; cAMP-dependent protein kinase; Phosphodiesterase; Signal transduction; Reporter enzyme; Adenylyl cyclase; Calmodulin; Calcium; Cyclic nucleotide;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Pkh1 interacts with and phosphorylates components of the yeast Gcn2/eIF2α system

Keywords: GAAC; general amino acid control; HM; hydrophobic motif; PIF; PDK1-interacting fragment; Yeast; Gcn2; PDK1; Pkh1-3; PKA; Sch9; PKB;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Roles of hinge region, loops 3 and 4 in the activation of Escherichia coli cyclic AMP receptor protein

Keywords: cAMP; 3′,5′-cyclic adenosine monophosphate; PKA; protein kinase A; Epac; exchange protein directly activated by cAMP; CRP; cAMP receptor protein; CNGC; cyclic nucleotide-gated ion channels; WT; wild-type; TEK100; 50 mM Tris 1 mM EDTA and 100 mM KCl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

d-Dopachrome tautomerase promotes IL-6 expression and inhibits adipogenesis in preadipocytes

Keywords: AT; adipose tissue; SVF; stromal vascular fraction; DDT; d-dopachrome tautomerase; MIF; macrophage migration inhibitory factor; PKA; protein kinase A; AMPK; AMP-activated protein kinase; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine seru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Solvent effects on the absorption spectra of arginine-salicylaldimine

Keywords: Arginine-salicylaldimine; Solvent-solute interaction; Density functional calculations; UV/vis spectra; Keto-enol equilibrium; pKa;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Ab initio studies on acidity and tautomeric equilibrium constants of some benzoxa-, benzothia-, benzoselena-zolinone derivatives

Keywords: HF; DFT; pKa; CPCM; Thermodynamic;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Accurate pKa calculations for trimethylaminium ion with a variety of basis sets and methods combined with CPCM continuum solvation methods

Keywords: pKa; DFT; CPCM; Solvation energy; G2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons

Keywords: ALS; amyotrophic lateral sclerosis; CHIP; C-terminus of Hsc70 interacting protein; db-cAMP; dibutyryl-cAMP; DMSO; dimethyl sulfoxide; p62/sqstm1; sequestosome1; PKA; cAMP-dependent protein kinase; PGJ2; prostaglandin J2; Rp-cAMPS; adenosine 3′,5′-cycl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

π-Charge distribution in some (4-R1-phenyl)bis(ethylsulfonyl)methane and (4-R1-phenyl)bis(benzylsulfonyl)methane carbanions in acetonitrile

Keywords: Proton transfer; Carbon acids; Carbanion; Electron density; pKa; Acetonitrile;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

FTIR, FT-Raman, SERS and DFT study on melamine

Keywords: Melamine; IR; Raman; SERS; DFT; pKa

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular modeling of protonic acid doping of emeraldine base polyaniline for chemical sensors

Keywords: Molecular mechanics; Molecular dynamics; pKa; Doping percentage; Emeraldine base polyaniline

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Self-organizing molecular field analysis of NSAIDs: Assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach

Keywords: NSAIDs; Vd; 3D-QSPkR; SOMFA; pKa;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Efficient decarbonation of carbonate-type layered double hydroxide (CO32−LDH) by ammonium salts in alcohol medium

Keywords: LDH; Layered double hydroxide; Deintercalation of carbonate; Ammonium salt; pKa

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه