دانلود مقالات ISI درباره Pka + ترجمه فارسی

The role of TRPV4 in fibrosis

Keywords: α-SMA; α-smooth muscle actin; aa; amino acids; AHF; alcohol/high fat diet; AIP4; atrophin-interacting protein 4; ANK; ankyrin; ARS-L; arachidonate-like recognition sequence; ASL; airway surface liquid; BKCa; Ca2 +-dependent K+; [Ca2 +]i; intracellular

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

PKA phosphorylation of Cav1.2 channel modulates the interaction of calmodulin with the C terminal tail of the channel

Keywords: Ca2+ channels; Cav1.2; Calmodulin; PKA; Phosphorylation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

G protein-coupled receptor kinases: Past, present and future

Keywords: αN-helix; N-terminal α-helical domain; α2AAR; α2A-adrenergic receptor; AST; active site tether; βAR; β-adrenergic receptor; β2AR; β2-adrenergic receptor; βARK; β-adrenergic receptor kinase; CLBD; C-terminal lipid binding domain; EM; electron mic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Activated mitochondrial apoptosis in hESCs after dissociation involving the PKA/p-p53/Bax signaling pathway

Keywords: Human embryonic stem cells; Dissociation; Mitochondrial apoptosis pathway; PKA; P-p53;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Microcystin-leucine arginine inhibits gonadotropin-releasing hormone synthesis in mice hypothalamus

Keywords: AAV; Adeno-associated virus; cAMP; Cyclic adenosine monophosphate; ChIP; Chromatin immunoprecipitation; Co-IP; Coimmunoprecipitation; CREB; cAMP response element-binding protein; FBS; Fetal bovine serum; GnRH; Gonadotropin-releasing hormone; MC-LR; Microc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Influence of pKa on solvent performance of MAPA promoted tertiary amines

Keywords: Amine solvents; CO2 absorption; Cyclic capacity; Absorption rate; pKa;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Expression and localization of phosphodiesterase 2A in the submandibular gland of mice

Keywords: cAMP; cyclic AMP; cGMP; cyclic GMP; PDE2A; phosphodiesterase 2A; NGF; nerve growth factor; PKA; protein kinase A; PKG; protein kinase G; PKG1; protein kinase G1; RT; PCR, reverse transcription-polymerase chain reaction; Serpinb6a; serine (or cysteine) pep

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting histone deacetylation for recovery of maternal deprivation-induced changes in BDNF and AKAP150 expression in the VTA

Keywords: A-kinase anchoring protein (AKAP); Dopamine; Histone deacetylase (HDAC); Histone deacetylase inhibitor (HDAC inhibitor); Brain derived neurotrophic factor (BDNF); Ventral tegmental area (VTA); Early life stress; Maternal deprivation (MD); Epigenetics; His

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes

Keywords: Gluconeogenesis; E2F1; Liver metabolism; Hyperglycemia; Diabetes; Cell cycle regulators; PCK1; Phosphoenolpyruvate carboxykinase 1; G6PC; glucose-6-phosphatase G6PC; PTT; Pyruvate tolerance test; CDK4; cyclin-cyclin-dependent kinase 4; PKA; protein kina

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Pb2 + modulates ryanodine receptors from the endoplasmic reticulum in rat brain

Keywords: Bmax; the maximal number of ryanodine-binding site; Ca2 +;  calcium ion; cADPR; cyclic ADP-ribose; ER; endoplasmic reticulum; GSH; reduced glutathione; Kd; the equilibrium binding constant; Mg2 +;  magnesium ion; Pb2 +;  lead ion; PKA; cAMP-dependen

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

5-HT1B receptor agonist CGS12066 presynaptically inhibits glutamate release in rat hippocampus

Keywords: CGS12066; 7-trifluoromethyl-4-(4-methyl-1-piperaziny)pyrrolo-[1,2-a]quinoxaline; 5-HT1B receptors; 5-hydroxytryptamine 1B receptors; 4-AP; 4-aminopyridine; GPCR; G protein-coupled receptor; AC; adenylate cyclase; PKA; protein kinase A; VGLUT1; vesicular t

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

HFpEF, a Disease of the Vasculature: A Closer Look at the Other Half

Keywords: cAMP; cyclic adenosine 3′,5′-monophosphate; cGMP; cyclic guanosine monophosphate; EF; ejection fraction; HFpEF; heart failure with preserved ejection fraction; HFrEF; heart failure with reduced ejection fraction; KO; knockout; LV; left ventricular; LZ

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Schwann cells protect against CaMKII- and PKA-dependent Acrylamide-induced Synapsin I phosphorylation

Keywords: Acrylamide; Synapsin I; CaMKII; PKA; MAPK-Erk;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanism of noradrenaline-induced α1-adrenoceptor mediated regulation of Na-K ATPase subunit expression in Neuro-2a cells

Keywords: Brain excitability; cAMP; PKA; Ca++; Prazosin; Propranolol; REM sleep; Transcriptional regulation.;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Involvement of the NO/sGC/cGMP/K+ channels pathway in vascular relaxation evoked by two non-quinazoline α1-adrenoceptor antagonists

Keywords: 4-AP; 4-amynopiridine; AC; adenylyl cyclase; BPH; benign prostatic hyperplasia; COX; cyclooxygenase; DAG; diacylglycerol; EDHF; endothelium-derived hyperpolarizing factor; eNOS; endothelial NO synthase; GLI; glibenclamide; HAEC; human aortic endothelial c

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

The multifaceted role of glutathione S-transferases in cancer

Keywords: Glutathione-S transferase; Carcinogenesis; Biomarkers; Drug resistance; Tumor suppressor; AD; Aricaidine; AP-1; Activator protein 1; ASK1; Apoptosis signal-regulating kinase; CSC; cancer stem cells; EGFR; Epidermal growth factor receptor; GSH; glutathione

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Mitochondrial cAMP-PKA signaling: What do we really know?

Keywords: Mitochondria; cAMP; PKA; AKAP; Phosphorylation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

Keywords: AOPs; Adverse Outcome Pathways; FSANZ; Food Standards Australia New Zealand; HTE; High Throughput Exposure; HTS; high throughput screening; ILSI; International Life Sciences Institute; HESI; Health and Environmental Sciences Institute; RISK21; Risk Assess

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation

Keywords: Tri-agonist; Signaling cascade; Pancreatic islets; Insulin secretion; G proteins; TRP channels; AC; Adenylyl cyclase; cAMP; Cyclic adenosine monophosphate; ECL; Extracellular loop; EPAC; Exchange protein directly activated by cAMP; FCS; Fetal calf serum;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Anoctamin 9/TMEM16J is a cation channel activated by cAMP/PKA signal

Keywords: Anoctamins; PKA; cAMP; Cation channel; Calcium;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

HSP70 Facilitates Memory Consolidation of Fear Conditioning through MAPK Pathway in the Hippocampus

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CAMK; Ca2+/calmodulin-dependent protein kinase; CFC; Contextual Fear Conditioning; CNS; central nervous system; CREB; cAMP responsive element-binding protein; ERK; extracellular signal-regulated

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Lrp6 is a target of the PTH-activated αNAC transcriptional coregulator

Keywords: αNAC; α chain of nascent polypeptide associated complex; PTH; Parathyroid Hormone; PKA; protein kinase A; ChIP; chromatin immunoprecipitation; ChIP-Seq; ChIP-sequencing; LRP6; Low density lipoprotein receptor-Related Protein 6; iPTH; intermittent PTH; P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Hybrid DFT study on non-covalent interactions and their influence on pKa's of magnesium-carboxylate complexes

Keywords: Solvation; SMD; pKa; ELF; AIM;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Selective inhibition of histamine-evoked Ca2+ signals by compartmentalized cAMP in human bronchial airway smooth muscle cells

Keywords: AC; adenylyl cyclase; 2-APB; 2-aminoethoxyphenylborane; ASM; airway smooth muscle; cAMP; 3',5'-cyclic AMP; COPD; chronic obstructive pulmonary disease; [Ca2+]i; intracellular free Ca2+ concentration; DMSO; dimethyl sulfoxide; EC50 (IC50); half-maximally e

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

β-Adrenergic regulation of cardiac type 2A protein phosphatase through phosphorylation of regulatory subunit B56δ at S573

Keywords: ARVM; adult rat ventricular myocytes; CaMKII; calcium/calmodulin-dependent kinase II; cMyBP-C; cardiac myosin binding protein-C; cTnI; cardiac troponin I; I-1; inhibitor of protein phosphatase-1; ISO; isoprenaline; KO; knock out; MOI; multiplicity of infe

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22 Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration

Keywords: Gene Regulation; Mouse Model; Ulcerative Colitis; Tissue Repair; cAMP; adenosine 3′,5′-cyclic monophosphate; DSS; dextran sulfate sodium; GI; growth inhibitory; IL; interleukin; lncRNA; long noncoding RNA; LPS; lipopolysaccharide; MIR675; microRNA 675

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Prostaglandin E2 as a Regulator of Immunity to Pathogens

Keywords: AA; Arachidonic Acid; BMT; Bone marrow transplant; cAMP; Cyclic adenosine monophosphate; COX; Cyclooxygenase; EP; E-type prostanoid; EPAC; Exchange protein directly activated by cAMP; ERK; Extracellular signal-regulated kinases; GSK-3; Glycogen synthase k

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Sex-specific effects of CB1 receptor antagonism and stress in adolescence on anxiety, corticosterone concentrations, and contextual fear in adulthood in rats

Keywords: CB1; cannabinoid receptor type-1; PFC; prefrontal cortex; DH; dorsal hippocampus; PND; postnatal day; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; CORT; corticosterone; GAD67; glutamic acid decarboxyla

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Review of recent developments and persistent challenges in stability of perovskite solar cells

Keywords: PSC; perovskite solar cells; UV; ultraviolet; PV; photovoltaic; MA; methylammonium; XRD; X ray diffraction; RH; Relative humidity; XPS; X-ray photoelectron spectroscopy; Spiro-OMeTAD; N2,N2,N2′,N2′,N7,N7,N7′,N7′-octakis(4-methoxyphenyl)− 9,9â€

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Selectively targeting prostanoid E (EP) receptor-mediated cell signalling pathways: Implications for lung health and disease

Keywords: ASM; airway smooth muscle; BAL; bronchoalveolar; CHO; Chinese hamster ovary; COX; cyclooxygenase; EP; prostanoid E; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptors; GSK-3; glucogen synthase kinase-3; HMLC; human lung mast cel

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Sustained β-AR stimulation induces synthesis and secretion of growth factors in cardiac myocytes that affect on cardiac fibroblast activation

Keywords: α-SMA; α-smooth muscle actin; AC; adenylate cyclase; 6-Bnz-cAMP; N6-benzoyladenosine-3′,5′-cyclic monophosphate; cAMP; cyclic adenosine monophosphate; COL1A1; collagen type I alpha1; COL1A2; collagen type I alpha2; CTGF; connective tissue growth fac

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells

Keywords: G-protein coupled receptors; Interleukin-1β; C-Jun N-terminal kinase; Purinergic receptors; Inflammation; YM-254890 (PubChem CID: 9919454); H-89 (PubChem CID: 449241); NF340 (PubChem CID: 73755007); MRS2179 (PubChem CID: 24867852); ZM241385 (PubChem CID:

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Dually modified transmembrane proteoglycans in development and disease

Keywords: ActR; activin type receptor; ALK; activin receptor like kinase; AV; atrioventricular cushion; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; C1; conserved domain 1; C2; conserved domain 2; Cdc42; control protein 42 homolog; CS

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation

Keywords: DNMT1; DNA-methyltransferase 1; FOXO; Forkhead box O transcription factors; GST; glutathione S-transferase; HBP1; HMG-box protein 1; HEK; human embryonic kidney; HMG; high mobility group; HPLC; high performance liquid chromatography; KD; kinase dead; MS;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

The origin of GSKIP, a multifaceted regulatory factor in the mammalian Wnt pathway

Keywords: Bioinformatics; DUF727; GSKIP; PKA; GSK3β; Wnt pathway;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular and functional characterization of tumor-induced factor (TIF): Hamster homolog of CXCL3 (GROγ) displays tumor suppressive activity

Keywords: CXCL1; CXCL3; CXCR2; GRO; IL-8; MAS; Tumor-induced factor; Chemokine; Ab; antibody; CHO-K1; Chinese hamster ovary-K1; CNV; copy number variation; CXCR2; CXC chemokine receptor 2; CRE; cAMP-response elements; DCIP1; dendritic cell inflammatory protein 1; D

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A

Keywords: AC; adenylyl cyclase; AD; Alzheimer's disease; Akt; protein kinase B; Aβ; beta-amyloid; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin, CRE, cyclic AMP response element; CREB; CRE-binding protein; GABA; γ-aminobutyric acid; GFAF; glial

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Cyclic 3′,5′-adenosine monophosphate (cAMP) signaling in the anterior pituitary gland in health and disease

Keywords: cAMP; PKA; Pituitary gland; Second messenger; Somatotropinoma; Pituitary adenoma;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Focusing on claudin-5: A promising candidate in the regulation of BBB to treat ischemic stroke

Keywords: 5α-DHP; 5α-dihydroprogestrone; ABC; ATP-binding cassette; AF6; ALL-1-fused gene from chromosome 6; ALL; acute lymphoblastic leukemia; AMPAR; amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor; Ang-1; angiopoietin-1; AP-1; activator protein-1; BBB;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

A conjugate of decyltriphenylphosphonium with plastoquinone can carry cyclic adenosine monophosphate, but not cyclic guanosine monophosphate, across artificial and natural membranes

Keywords: cAMP; adenosine 3′,5′-cyclic monophosphate; cGMP; guanosine 3′,5′-cyclic monophosphate; 8-Br-cAMP; 8-bromoadenosine 3′,5′-cyclic monophosphate; 8-Br-cGMP; 8-bromoguanosine 3′,5′-cyclic monophosphate; PKA; protein kinase A; PKG; protein kin

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

А theoretical study on ionization of sartans in aqueous media and on interactions with surfactant micelles

Keywords: AT1 receptor antagonists; pKa; Ampholytes; DFT study; Molecular descriptors; B3LYP method;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Suitability of the AUC Ratio as an Indicator of the Pharmacokinetic Advantage in HIPEC

Keywords: Clinical pharmacokinetics; Simulations; Cancer chemotherapy; Absorption; Mathematical models; Clearance; HIPEC; hyperthermic intraoperative peritoneal chemotherapy; iv; intravenous; PKA; pharmacokinetic advantage; ka; absorption rate constant; ka_app; app

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Acute epileptiform activity induced by gabazine involves proteasomal rather than lysosomal degradation of KCa2.2 channels

Keywords: Gabazine; Epilepsy; KCa2.2; UCL1684; PKA;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

The importance of pKa in an analysis of the interaction of compounds with DNA

Keywords: pKa; Alizarin; Purpurin; Contribution of species; K0; K−; pH;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Epigallocatechin-3-gallate protects against 1,3-dichloro-2-propanol-induced lipid accumulation in C57BL/6J mice

Keywords: EGCG; 1,3-DCP; Lipid accumulation; In vivo; AMPK; PKA;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Post-translational modifications at the ATP-positioning G-loop that regulate protein kinase activity

Keywords: cAbl; abelson murine leukemia virus proto-oncogene; BCR; breakpoint cluster region; CDK; cyclin-dependent kinase; CML; chronic myeloid leukemia; IR; insulin receptor; O-GlcNAc; O-linked β-N-acetyl glucosamine; PKA; protein kinase A; PKC; protein kinase C

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Odor-taste learning in Drosophila larvae

Keywords: MB; mushroom body; KC; Kenyon cell; CS; conditioned stimulus; US; unconditioned stimulus; ORN; olfactory receptor neuron; LN; local neuron; PN; projection neuron; GRN; gustatory receptor neurons; SEZ; subesophageal zone; DA; dopamine; OA; octopamine; Syn;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Translating in vitro ligand bias into in vivo efficacy

Keywords: BRET; bioluminescence resonance energy transfer; DPD; deoxypyridinoline; GPCR; G protein-coupled receptor; RAi; intrinsic relative activity; NHERF2; Na+/H+ exchanger regulatory factor 2; PKA; protein kinase A; PKC; protein kinase C; PTH; parathyroid hormo

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion

Keywords: Bax; Bcl-2 associated x protein; Bcl-2; B-cell lymphoma-2; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; CREB; cAMP-response element binding protein; GFAP; glial fibrillary acidic protein; H&E; haematoxylin and eosin; Iba-1; ionized c

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Cardiotonic actions of quercetin and its metabolite tamarixetin through a digitalis-like enhancement of Ca2+ transients

Keywords: Quercetin; Tamarixetin; Digitalis; Inotropic action; Cardiomyocyte; Ca2+ transient; bmp; beats per minute; CaT; Ca2+ transients; COMT; catechol-O-methyl transferase; cTnI; cardiac troponin I; cTnT; cardiac troponin T; DCM; dilated cardiomyopathy; DIG; dig

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه