دانلود مقالات ISI درباره Pkm2 + ترجمه فارسی

Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics

Keywords: 3D lrECM; three-dimensional cultures of laminin-rich extracellular matrix; ACs; adenylyl cyclases; AKAP; A-kinase anchoring protein; ATP; adenosine triphosphate; β-AR; β adrenergic receptor; β-arr2; β-arrestin 2; BnT; benzylthio group; cAB; cAMP-bindi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells

Keywords: Gem; gemictabine; PKM2; pyruvate kinase isoenzymes muscle type 2; CASP3/7; caspase 3 & 7; c. PARP; cleaved poly ADP ribose polymerase; BAX; BCL2-associated X protein; CDKN1A; cyclin-dependent kinase inhibitor 1A; BAK1; BCL2-antagonist; Bcl-xL; BCL2-like 1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells

Keywords: ACO; aconitase; ASK1; apoptosis signal-regulating kinase 1; Bcl-2; B-cell lymphoma 2; CaM; calmodulin; CD95; cluster of differentiation 95; DTNB; 5,5-dithio-bis-2-nitrobenzoic acid; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Pyruvate kinase M2 interacts with DNA damage-binding protein 2 and reduces cell survival upon UV irradiation

Keywords: PKM2; DDB2; UV; Cell survival; Tumorigenesis;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy

Keywords: GBM; glioblastoma multiforme; let-7a; lethal-7a; miRNA; microRNA; TCGA; The Cancer Genome Atlas; GLUT; glucose transporter; PKM2; pyruvate kinase M2; PDK; pyruvate dehydrogenase kinase; MGMT; O6-methylguanine-DNA methyltransferase; GSK3β; glycogen syntha

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Pyruvate kinase M2 and cancer: an updated assessment

Keywords: PKM2; Cancer metabolism; Warburg effect;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling

Keywords: Colorectal cancer; PKM1; PKM2; Migration; Adhesion;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PARP and other prospective targets for poisoning cancer cell metabolism

Keywords: ATP; adenosine 5′-triphosphate; 3-BrPA; 3-bromopyruvate; EGFR; epidermal growth factor receptor; FDA; food and drug administration; GSH; glutathione; GSSG; oxidized GSH; GST; glutathione S-transferase; HDAC; histone deacetylase; HIF1; hypoxia inducible

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2014 سفارش ترجمه

6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met

Keywords: 6PGD; 6-phosphogluconate; PPP; pentose phosphate pathway; PKM2; pyruvate kinase M2; LDHA; lactate dehydrogenase A; FBS; fetal bovine serum; HGF; human hepatocyte growth factor; 6-Phosphogluconate dehydrogenase; Glucose metabolism; Glycolytic tumors; c-Met

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of proteomic signatures associated with lung cancer and COPD

Keywords: 2D-PAGE; Two dimensional electrophoresis; AKR1B10; Aldo-keto reductase family 1, member B10; AKR1C3; Aldo-keto reductase family 1, member C3; ALDH3A1; Aldehyde dehydrogenase 3 family, member A1; ALDOA; Aldolase A; AMY1A; Alpha 1 amylase; AMY2A; Alpha 2 am

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of the mitochondrial Hsp90 chaperone network: A novel, efficient treatment strategy for cancer?

Keywords: 17-AAG; 17-N-Allylamino-17-demethoxygeldanamycin; AMPK; AMP-activated kinase; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; CsA; Cyclosporin A; CyD; Cyclophilin-D; G-G4; Gamitrinib(s), Geldanamycin (GA), mitochondrial matrix inhibitors - Gamitrinib â€

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators

Keywords: M2 isoform of pyruvate kinase; PKM2; PKM2 activator; PKM2 activation; PKM1; Cancer metabolism; Warburg effect; Anti-tumor; Anti-cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation and function of pyruvate kinase M2 in cancer

Keywords: PKM2; The Warburg effect; Gene expression

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Pyruvate kinase M2 promotes the growth of gastric cancer cells via regulation of Bcl-xL expression at transcriptional level

Keywords: PKM2; NF-κB; Bcl-xL; Gastric cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer

Keywords: cancer; pyruvate kinase; PKM2; cancer metabolism; cancer therapeutics

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

1-(sulfonyl)-5-(arylsulfonyl)indoline as activators of the tumor cell specific M2 isoform of pyruvate kinase

Keywords: PKM2; Pyruvate kinase; Cellular metabolism; Anti-cancer strategies; Small molecule activators

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase

Keywords: PKM2; Pyruvate kinase; Cellular metabolism; Anti-cancer strategies; Small molecule activators

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Thyroid hormone differentially modulates Warburg phenotype in breast cancer cells

Keywords: T3; triiodothyronine; T4; thyroxine; 2NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diaxol-4-yl)amino]-2-deoxyglucose; DCFDA; 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester; TMRM; tetramethyl rhodamine methyl ester; ROS; reactive

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Investigation of candidate genes for glycolytic potential of porcine skeletal muscle: Association with meat quality and production traits in Italian Large White pigs

Keywords: Candidate genes; PRKAG3; PGAM2; PKM2; Meat quality and production traits

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

Keywords: Oct-4; PKM2; Embryonic stem cell; Self-renewal; Protein–protein interaction; Transactivation; Coactivator

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Profiling molecular targets of TGF-β1 in prostate fibroblast-to-myofibroblast transdifferentiation

Keywords: Actg2; actin, gamma 2, smooth muscle; bFGF; basic fibroblast growth factor; Cdk; cycline-dependent kinase; Cks1; Cdc28 protein kinase 1; Comp; cartilage oligomeric matrix protein; Ctgf; connective tissue growth factor; Dkk3; dickkopf3; Elf1a; elongation f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه