Keywords: پلامباگین; Hydroxynaphthoquinone; Naphthoquinone; Lawsone; Plumbagin; Lapachol; Bis-lawsone;
مقالات ISI پلامباگین (ترجمه نشده)
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Keywords: پلامباگین; AtKAPAS; Herbicide; Toxicity; Plumbagin; Bioisostere; Virtual screening
Keywords: پلامباگین; CUMS, chronic unpredictable mild stress; MAO, monoamine oxidase; MDA, malondialdehyde; TST, tail suspension testAntidepressant; Corticosterone; Depression; Chronic unpredictable mild stress; Plumbagin
Keywords: پلامباگین; Plumbagin; Thioredoxin reductase; Glutathione reductase; Reactive oxygen species; Anticancer;
Keywords: پلامباگین; Plumbagin; Breast cancer; NF-κB; Molecular docking;
Keywords: پلامباگین; PL; plumbagin; DCs; dendritic cells; TLRs; toll like receptors; iDCs; immature dendritic cells; mDCs; mature dendritic cells; CNS; central nervous system; PBMCs; peripheral blood mononuclear cells; GM-CSF; granulocyte-macrophage colony-stimulating factor;
Keywords: پلامباگین; RifR; rifampicin resistant; his; histidine; PL; plumbagin; JU; juglone; ME; menadione; AP; antimutagenic potential; SR; spontaneous reversion; SPC; standard plate count; aRNA; amplified RNA; cfu; colony-forming units; WT; wild type.; Naphthoquinones; Anti
Plumbagin suppresses the human large cell lung cancer cell lines by inhibiting IL-6/STAT3 signaling in vitro
Keywords: پلامباگین; Plumbagin; Proliferation; Invasion; IL-6; STAT3; Large cell lung cancer;
Novel anticancer hybrids from diazen-1-ium-1,2-diolate nitric oxide donor and ROS inducer plumbagin: Design, synthesis and biological evaluations
Keywords: پلامباگین; Nitric oxide; Reactive oxygen species; Plumbagin; Cytotoxicity; Selectivity;
Plumbagin ameliorates memory dysfunction in streptozotocin induced Alzheimer's disease via activation of Nrf2/ARE pathway and inhibition of β-secretase
Keywords: پلامباگین; Plumbagin; GFAP; Astrocytes; Trigonelline; β-secretase; Alzheimer's disease;
Plumbagin inhibits neuronal apoptosis, intimal hyperplasia and also suppresses TNF-α/NF-κB pathway induced inflammation and matrix metalloproteinase-2/9 expression in rat cerebral ischemia
Keywords: پلامباگین; Apoptosis; Cerebral infarction; Inflammation; Matrix metalloproteinases; Nuclear factor-kappa B; Plumbagin;
Isolation and characterization of plumbagin (5- hydroxyl- 2- methylnaptalene-1,4-dione) producing endophytic fungi Cladosporium delicatulum from endemic medicinal plants
Keywords: پلامباگین; Endophytic fungi; Cladosporium delicatulum; Structural characterization; Plumbagin; Biological activities;
Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites
Keywords: پلامباگین; CYP4A11; Reaction phenotyping; HET0016; Plumbagin; Lauric acid metabolism; HLM; human liver microsomes; CYP; cytochrome P450; 20-HETE; 20-hydroxyeicosatetraenoic acids; LC-MS/MS; liquid chromatography-tandem mass spectrometry; IC50; the half maximal inh
Original articleNrf2 and NF-κB modulation by Plumbagin attenuates functional, behavioural and biochemical deficits in rat model of neuropathic pain
Keywords: پلامباگین; Chronic constriction injury; Plumbagin; Neuroinflammation; Oxidative stress; Neuropathic pain;
Original ArticleSynergistic inhibitory effects of Celecoxib and Plumbagin on melanoma tumor growth
Keywords: پلامباگین; Celecoxib; Plumbagin; Synergy; COX-2; STAT3; Tumor development;
The attenuating effects of plumbagin on pro-inflammatory cytokine expression in LPS-activated BV-2 microglial cells
Keywords: پلامباگین; Plumbagin; Cytokines; Nitric oxide; Microglial cells; Neuroprotection; Anti-inflammatory;
Targeting thioredoxin reductase by plumbagin contributes to inducing apoptosis of HL-60Â cells
Keywords: پلامباگین; Plumbagin; Thioredoxin reductase; Oxidative stress; Apoptosis; Anticancer; BSO; l-buthionine-(S,R)-sulfoximine; DCFH-DA; 2â², 7'-dichlorfluorescein diacetate; DHE; dihydroethidium; DTNB; 5, 5'-dithiobis-2-nitrobenzoic acid; GR; glutathione reductase;
In situ determination of potential-driven structural changes in a redox-active plumbagin polymer film on a glassy carbon electrode using PM IRRAS under electrochemical control
Keywords: پلامباگین; Redox-active polymer; Plumbagin; Quinone redox reaction; In situ spectroelectrochemistry;
Chitosan elicitation and sequential Diaion® HP-20 addition a powerful approach for enhanced plumbagin production in Plumbago indica root cultures
Keywords: پلامباگین; Chitosan; Elicitation; Diaion® HP-20; In situ adsorption; Plumbagin; Plumbago rosea;
Novel NO-releasing plumbagin derivatives: Design, synthesis and evaluation of antiproliferative activity
Keywords: پلامباگین; Plumbagin; NO-Releasing; Cytotoxicity; Selectivity; Stability;
Novel juglone and plumbagin 5-O derivatives and their in vitro growth inhibitory activity against apoptosis-resistant cancer cells
Keywords: پلامباگین; Juglone; Plumbagin; In vitro growth inhibition; Cancer; 1,4-Naphthoquinones;
Application of SPECT/CT imaging system and radiochemical analysis for investigation of blood kinetics and tissue distribution of radiolabeled plumbagin in healthy and Plasmodium berghei-infected mice
Keywords: پلامباگین; Plumbagin; Technetium-99m; Biodistribution; SPECT/CT imaging system
Potential mode of action of a novel plumbagin as a mosquito repellent against the malarial vector Anopheles stephensi, (Culicidae: Diptera)
Keywords: پلامباگین; Malarial vector; Plumbagin; FT-IR; NMR; Enzyme; Histology;
Ruthenium(II) p-cymene complexes of naphthoquinone derivatives as antitumor agents: A structureâactivity relationship study
Keywords: پلامباگین; Ru(II) complex; Naphthoquinone; Cytotoxicity; Hypoxia; Apoptosis; Lap; lapachol; Plum; plumbagin; Law; lawsone; Jug; juglone; PTA; 1,3,5-triaza-7-phosphaadamantane; LDH; Lactate Dehydrogenase; PBS; phosphate-buffered saline; IC50; half maximal inhibitory
Plumbagin triggers DNA damage response, telomere dysfunction and genome instability of human breast cancer cells
Keywords: پلامباگین; Plumbagin; DNA damage; Cell death; Telomeres; Telomerase; Breast Cancer Cells
Oxidative stress modulates the cytokine response of differentiated Th17 and Th1 cells
Keywords: پلامباگین; PB; Plumbagin; IFN-γ; Interferon-Gamma; IL-17; Interleukin-17; ROS; Reactive Oxygen Species; O2.â; Super oxide; H2O2; Hydrogen peroxide; TF; Transcription factor; Th2; T helper 2; Th17; T helper 17; PMA/Ion; Phorbol 12-myristate 13-acetate/Ionomycin; N
In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes
Keywords: پلامباگین; Metabolism; Human liver microsomes; Plumbagin; Cytochrome P450; Enzyme inhibition
Plumbagin inhibits growth of gliomas in vivo via suppression of FOXM1 expression
Keywords: پلامباگین; Glioma; Plumbagin; Proliferation; Apoptosis; FOXM1
Radiosensitizing potential of Plumbagin in B16F1 melanoma tumor cells through mitochondrial mediated programmed cell death
Keywords: پلامباگین; DCFH-DA; 2â²,7â²-dicholorofluorescein diacetate; Ψm; mitochondrial membrane potential; PARP; poly (ADP-ribose) polymerase; PI; propidium iodide; PLB; Plumbagin; RIPA; radioimmunoprecipitation assay; ROS; reactive oxygen species; RT; radiation; SER; sen
Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells
Keywords: پلامباگین; Plumbagin; DNA damage; Cell death; Telomeres and telomerase; Cancer therapeutics;
Folate-functionalized human serum albumin carrier for anticancer copper(II) complexes derived from natural plumbagin
Keywords: پلامباگین; Copper(II) complex; Human serum albumin; Plumbagin; Folate; Drug carrier;
Plumbagin as colorimetric and ratiometric sensor for arginine
Keywords: پلامباگین; Plumbagin; Colorimetric and ratiometric sensor; Arginine; Intramolecular proton transfer; DFT calculations;
Synthesis, characterization, molecular docking and anti-tubercular activity of Plumbagin-Isoniazid Analog and its β-cyclodextrin conjugate
Keywords: پلامباگین; Plumbagin; Plumbagin-Isoniazid Analog; β-Cyclodextrin; Inclusion complex; Antitubercular activity; Molecular docking;
Synthesis and anticancer activity of some novel 5,6-fused hybrids of juglone based 1,4-naphthoquinones
Keywords: پلامباگین; Juglone; Plumbagin; Anticancer activity; Apoptosis; Cell cycle arrest
Assessment of genotoxicity of catecholics using impedimetric DNA-biosensor
Keywords: پلامباگین; Catechol; DNA damage; Electrochemical impedance spectroscopy; DNA based biosensor; Plumbagin; Glutathione
Ferrocene and (arene)ruthenium(II) complexes of the natural anticancer naphthoquinone plumbagin with enhanced efficacy against resistant cancer cells and a genuine mode of action
Keywords: پلامباگین; Plumbagin; Ruthenium; Ferrocene; Anticancer drugs; Multi-drug resistance;
The in vitro anthelmintic effects of plumbagin on newly excysted and 4-weeks-old juvenile parasites of Fasciola gigantica
Keywords: پلامباگین; DMSO, dimethyl sulphoxide; TCZ, triclabendazole; PB, 5-hydroxy-2-methyl-1,4-naphthoquinone; NEJ, newly excysted juvenileFasciola gigantica; Anthelmintic; Plumbagin; Juvenile
Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells
Keywords: پلامباگین; Plumbagin; Non-small-cell lung cancer; Apoptosis; Autophagy; PI3K/Akt/mTOR
Anti-inflammatory, antimicrobial and antioxidant activities of Diospyros bipindensis (Gürke) extracts and its main constituents
Keywords: پلامباگین; Diospyros bipindensis; Respiratory disorders; Plumbagin; Ismailin; Anti-inflammatory; Antioxidant;
Anticancer activity and SAR studies of substituted 1,4-naphthoquinones
Keywords: پلامباگین; 1,4-Naphthoquinone; Plumbagin; Juglone; LLL12.1; Menadione; STAT3;
Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasis
Keywords: پلامباگین; Plumbagin; Sanguinarine; Chemotherapy; Schistosomiasis
The anthelmintic effect of plumbagin on Schistosoma mansoni
Keywords: پلامباگین; DMSO, dimethyl sulphoxide; PB, 5-hydroxy-2-methyl-1,4-naphthoquinone; PZQ, praziquantelSchistosoma mansoni; Plumbagin; Anthelmintic; Motility; Survival; Tegument
Plumbagin, a medicinal plant (Plumbago zeylanica)-derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model
Keywords: پلامباگین; Plumbagin; Prostate cancer; Orthotopic xenograft modelPL, plumbagin; PCa, prostate cancer; PKCε, protein kinase C epsilon; Stat3, signal transducers and activators of transcription 3
Possible mechanism of superoxide formation through redox cycling of plumbagin in pig heart
Keywords: پلامباگین; Plumbagin; Superoxide formation; Tetrameric carbonyl reductase; Pig heart;
Plumbagin as a new natural herbicide candidate for Sicyon angulatus control agent with the target 8-amino-7-oxononanoate synthase
Keywords: پلامباگین; 8-Amino-7-oxononanoate synthase; Plumbagin; Plumbago auriculata; Sicyos angulatus
Rapid method for isolation of plumbagin, an alternative medicine from roots of Plumbago zeylanica
Keywords: پلامباگین; Plumbago zeylanica; Cold maceration; Plumbagin
Synthesis, characterization and preliminary cytotoxicity evaluation of five Lanthanide(III)–Plumbagin complexes
Keywords: پلامباگین; Plumbagin; Lanthanide(III) complex; Cytotoxicity; DNA binding
Immune responses to novel allergens and modulation of inflammation by vitamin K3 analogue: A ROS dependent mechanism
Keywords: پلامباگین; BAL; Bronchoalveolar Lavage; IL; Interleukin; IFN; Interferon; TNF; Tumor Necrosis Factor; SPT; Skin Prick Test; PHA; Phytohemagglutinin; ConA; Concanavalin A; PBMC; Peripheral Blood Mononuclear Cells; CHSS; Contributory Health Service Scheme; ROS; Reacti
Plumbagin induces ROS-mediated apoptosis in human promyelocytic leukemia cells in vivo
Keywords: پلامباگین; Plumbagin; Apoptosis; Leukemia; Reactive oxygen species; Xenograft
Plumbagin activates ERK1/2 and Akt via superoxide, Src and PI3-kinase in 3T3-L1 Cells
Keywords: پلامباگین; Plumbagin; NADPH oxidase; Extracellular signal-regulated kinase (ERK1/2); Akt; Src tyrosine kinase