Keywords: PPARA; PPARalpha; Intermittent fasting; Every-other-day fasting; Steatosis; Adaptive fasting response;
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Keywords: CVD; cardiovascular disease; FA; fatty acid; ECHA; trifunctional enzyme subunit alpha; ECHB; trifunctional enzyme subunit beta; THIM; 3-ketoacyl-CoA thiolase; ER; estrogen receptor; PPARA; peroxisome proliferator-activated receptor alpha; PRGC1; peroxisom
Keywords: 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ
Keywords: ABCG5; ATP-binding cassette, sub-family G (WHITE), member 5; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACSL4; acyl-coa synthetase long-chain family member 4; AKT1; V-akt murine thymoma viral oncogene homolog 1; AXIN1; axin 1; Control; C
Keywords: Genetic variability; Postnatal development; Brown adipocytes; Inguinal white fat; Interscapular brown fat; Reduced ambient temperature; Thermoneutrality; Gut microbiota; Bile acids; AMPK; AMP-activated protein kinase; BA; bile acid; BAP; brown adipocyte p
Keywords: Muscle mass; Glycine; Nutrition; Calorie restriction; Fat mass; ALA; alanine; Atf4; activating transcription factor 4; AUC; area under the curve; Bnip3; BCL2/adenovirus E1B interacting protein 3; Ccl2; chemokine(C-C motif) ligand 2; Ccl5; chemokine(C-
Keywords: Glycosaminoglycans; Weight loss; Fat loss; White adipose tissue; Oxidative metabolism; B2m; beta-2 microglobulin; BAT; brown adipose tissue; CCK; cholecystokinin; Cox5a; cytochrome c oxidase subunit Va; Cpt1a; carnitine palmitoyltransferase 1a (liver isof
Keywords: PAPS; 3â²-Phosphoadenosine 5â²-phosphosulfate; DTNB; 5,5â²-Dithiobis(2-nitrobenzoic acid); APAP; Acetaminophen; ALT; Alanine aminotrasferase; BSA; Bovine serum albumin; CCl4; Carbon tetrachloride; Ccr2; C-C chemokine receptor 2; CFB; Clofibrate; CD;
Keywords: Acaca; Acetyl-Coenzyme A carboxylase 1; Acly; ATP citrate lyase; Actb; Beta-actin; ANOVA; Analysis of variance; AUC; Area under the curve; Bax; Bcl2-associated X protein; Bcl2; B cell leukemia/lymphoma 2; Bscl2; Berardinelli-Seip congenital lipodystroph
Roles of microRNA in prostate cancer cell metabolism
Keywords: AMPK; adenosine monophosphate-activated protein kinase; HIF-1α; hypoxia-inducible factor 1-alpha; mTOR; mammalian target of rapamycin; PI3K/AKT; phosphatidylinositol 3-kinase; ATP; adenosine triphosphate; TCA cycle; tricarboxylic acid cycle; GLUTs; gluco
The reciprocal link between EVI1 and miRNAs in human malignancies
Keywords: EVI1; ecotropic virus integration site-1; MiR; microRNA; 3â²-UTR; 3â²-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m
Part B: Morphometric and transcriptomic responses to sub-chronic exposure to the polycyclic aromatic hydrocarbon phenanthrene in the fathead minnow (Pimephales promelas)
Keywords: PNPLA2; patatin-like phospholipase domain containing 2; APOE; apolipoprotein E; NPC1; Niemann-Pick disease, type C1; LCAT; lecithin-cholesterol acyltransferase; DGAT1; diacylglycerol O-acyltransferase 1; LRP1; low density lipoprotein-related protein 1 (al
Vacuolar protein sorting 13C is a novel lipid droplet protein that inhibits lipolysis in brown adipocytes
Keywords: Brown adipose tissue; Thermogenesis; Free fatty acids; ATGL; Perilipin 1; Oxidative genes; VPS13C; Vacuolar Protein Sorting 13C; BAT; brown adipose tissue; BAs; brown adipocytes; LDs; lipid droplets; ATGL; adipose triglyceride lipase; ABHD5; α-β hydrola
Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver
Keywords: GDF15; growth differentiation factor 15; UPR; unfolded protein response; IRE1α; inositol requiring enzyme 1 alpha; XBP1; x-box binding protein 1; STZ; streptozotocin; ChIP; chromatin immunoprecipitation; ERSE; ER stress-response element; Ppara; peroxisom
LAZ3 protects cardiac remodeling in diabetic cardiomyopathy via regulating miR-21/PPARa signaling
Keywords: LAZ3; Cardiac remodeling; Diabetes; miR-21; PPARa;
SP and KLF Transcription Factors in Digestive Physiology and Diseases
Keywords: Specificity Protein; Krüppel-Like Factor; Digestive System; Cancer; Stem Cells; Proliferation; Differentiation; Development; Apoptosis; Cell Cycle; APC; adenomatous polyposis coli; BAX; B-cell lymphoma 2-like protein 4; BCL2; B-cell lymphoma 2; COX2; c
Original ResearchFull Report: Clinical-LiverElafibranor, an Agonist of the Peroxisome ProliferatorâActivated Receptorâα and âδ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening
Keywords: PPARA; PPARD; NAFLD; fatty liver; bNAS; baseline NAS; CI; confidence interval; HDL; high-density lipoprotein; HOMA-IR; Homeostasis Model Assessment IndexâInsulin Resistance; ITT; intention to treat; NAFLD; nonalcoholic fatty liver disease; NAS; nonalcoh
Applied nutritional investigationA genetic variant of PPARA modulates cardiovascular risk biomarkers after milk consumption
Keywords: Milk; Nutrigenetics; PPARA; Lipid profile; rs135549;
1,25-Dihydroxyvitamin D3 modulates lipid metabolism in prostate cancer cells through miRNA mediated regulation of PPARA
Keywords: Androgen; Vitamin D; miRNA; PPARA; Lipogenesis; Prostate cancer;
Ellagic acid improves hepatic steatosis and serum lipid composition through reduction of serum resistin levels and transcriptional activation of hepatic ppara in obese, diabetic KK-Ay mice
Keywords: Ellagic acid; Resistin; ppara; Adipocytokine; Metabolic syndrome; Obese;
Different effects of PPARA, PPARG and ApoE SNPs on serum lipids in patients with coronary heart disease based on the presence of diabetes
Keywords: PPARA; peroxisome proliferator activated receptor-alpha; PPARG; peroxisome proliferator activated receptor-gamma; APOE; apolipoprotein e; CHD; coronary heart disease; TC; total-cholesterol; TG; triglyceride; LDL-C; LDL-cholesterol; HDL-C; HDL-cholesterol;
Transcriptomic and metabolomic signatures of an n-3 polyunsaturated fatty acids supplementation in a normolipidemic/normocholesterolemic Caucasian population
Keywords: AC; acylcarnitines; CRP; C-reactive protein; DHA; docosahexaenoic; ELISA; enzyme-linked immunosorbent assay; EPA; eicosapentaenoic; FA; fatty acid; FC; fold change; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; glyPC; glycerophosphatidylcholine; HDL-C;
Investigation of endocannabinoid system genes suggests association between peroxisome proliferator activator receptor-α gene (PPARA) and schizophrenia
Keywords: Schizophrenia; Cannabinoid system; PPARA; CNR1; NAPE-PLD; FAAH;
Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes
Keywords: Perfluoroalkyl acids; PPARA; Metabolic regulation; Species specificity; CAR; PXR; LXR;
Identification and characterization of a novel mouse peroxisome proliferator-activated receptor a-regulated and starvation-induced gene, Ppsig
Keywords: Fasting; mRNA differential display; PPARa; PPRE; Ppsig
The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: The Veterans Affairs HDL Intervention Trial (VA-HIT)
Keywords: Fibrate; HDL; Insulin resistance; PPARA; Polymorphism
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates
Keywords: Cholesterol; Hyperlipidemia; Microarray; Non-alcoholic steatohepatitis; PPARa; Triglyceride; APOE; Steatosis; Inflammation; Western diet
Contemporaneous carrier-state of two or three “proatherosclerotic” variants of APOE, ICAM1, PPARA and PAI-1 genes differentiate CAD patients from healthy individuals
Keywords: ACE; angiotensin converting enzyme; APOE; apolipoprotein E; BMI; body mass index; CAD; coronary artery disease; HDL; high density lipoprotein; ICAM1; intercellular adhesion molecule-1; LRP; LDL-related receptor; ox-LDL; oxidized low density lipoprotein; P