Keywords: پلاسمایی قبل از mRNA; U12-type introns; Minor spliceosome; Human diseases; Pre-mRNA splicing; Cryptic splice sites; Exon skipping; Intron retention;
مقالات ISI پلاسمایی قبل از mRNA (ترجمه نشده)
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Keywords: پلاسمایی قبل از mRNA; pre-mRNA splicing; Spliceosome assembly; Hydroxyl radical; Footprinting;
Keywords: پلاسمایی قبل از mRNA; Ca2+ channel; K+ channel; Ca2+-activated Clâ channel; Transcription; Pre-mRNA splicing; Protein degradation; AD; Alzheimer's disease; ADPR; ADP ribose; AITC; allyl isothiocyanate; AKAP; A-kinase anchoring protein; AMPK; 5â² AMP-activated protein kinase
Splicing activator RNPS1 suppresses errors in pre-mRNA splicing: A key factor for mRNA quality control
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; RNPS1; Aurora kinase B; Aberrant splicing; Splicing fidelity; mRNA quality control; ASO; antisense oligoribonucleotides; AURKB; aurora kinase B; CLIP; UV-crosslinking and immunoprecipitation; CPC; chromosome passenger complex; DAPI; 4â
Antisense oligonucleotide therapy rescues disruptions in organization of exploratory movements associated with Usher syndrome type 1C in mice
Keywords: پلاسمایی قبل از mRNA; Vestibular system; Visual system; Dead reckoning; Path integration; Spatial orientation; Home base; Pre-mRNA splicing; Antisense oligonucleotides; Usher syndrome; Harmonin; USH1C; Deafness;
A novel AMELX mutation causes hypoplastic amelogenesis imperfecta
Keywords: پلاسمایی قبل از mRNA; AMELX; Amelogenesis imperfecta; X-linked; Enamel; Pre-mRNA splicing;
Suppression of 5â² splice-sites through multiple exonic motifs by hnRNP L
Keywords: پلاسمایی قبل از mRNA; hnRNP L; 5â² splice-site selection; Pre-mRNA splicing; KLF6;
Ribosomal protein pNO40 mediates nucleolar sequestration of SR family splicing factors and its overexpression impairs mRNA metabolism
Keywords: پلاسمایی قبل از mRNA; pinin; pnn; amino acid; aa; Transgenic mice; Tg mice; SR proteins; serine-arginine proteins; pNO40; Nucleolus; SR family splicing factors; Pre-mRNA splicing; mRNA metabolism;
Trifluoromethyl arylamides with antileukemia effect and intracellular inhibitory activity over serine/arginine-rich protein kinases (SRPKs)
Keywords: پلاسمایی قبل از mRNA; Trifluoromethyl arylamides; SRPK; SRPIN340; Serine/arginine-rich protein kinase; Leukemia; Pre-mRNA splicing;
The Spliceosome: A Protein-Directed Metalloribozyme
Keywords: پلاسمایی قبل از mRNA; pre-mRNA splicing; spliceosome; cryo-EM structure; mechanism; metalloribozyme; snRNA; small nuclear RNA; BS; branch site; 5â²SS; 5â²-splice site; ILS; intron lariat spliceosome; snRNPs; small nuclear ribonucleoprotein particles; 3â²SS; 3â²-splice site
Structural studies of the endogenous spliceosome - The supraspliceosome
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; Supraspliceosome; Electron tomography; Scanning transmission electron microscopy mass measurements; Cryo-electron microscopy; Cryo-electron microscopy single particle reconstruction;
Protein arginine methylation of Npl3 promotes splicing of the SUS1 intron harboring non-consensus 5â² splice site and branch site
Keywords: پلاسمایی قبل از mRNA; Protein arginine methylation; Pre-mRNA splicing; U1 snRNP; Hmt1; Npl3;
CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B
Keywords: پلاسمایی قبل از mRNA; CRIPSR/Cas9; Pladienolide B; Spliceosome; Pre-mRNA splicing; Drug target validation; Drug discovery; SSNs; Site Specific Nucleases; ZFN; Zing Finger Nucleases; TALENs; Transcription Like Effector Nucleases; CRISPR; Clustered Regulatory Interspaced Short P
Long noncoding RNAs: Re-writing dogmas of RNA processing and stability
Keywords: پلاسمایی قبل از mRNA; MALAT1; MEN β; NEAT1; Triple helix; tRNA-like; Sno-lncRNA; Circular RNA; CircRNA; Pre-mRNA splicing; RNA stability; Polyadenylation;
Tip110: Physical properties, primary structure, and biological functions
Keywords: پلاسمایی قبل از mRNA; Tip110; Pre-mRNA splicing; Gene transcription; HIV replication; Development; Stem cell biology; Post-translational modifications
Nuclear phosphoproteomics analysis reveals that CDK1/2 are involved in EGF-regulated constitutive pre-mRNA splicing in MDA-MB-468 cells
Keywords: پلاسمایی قبل از mRNA; EGF; Nuclear phosphoproteomics; MDA-MB-468 cells; Pre-mRNA splicing; CDK1/2;
Human Mpn1 promotes post-transcriptional processing and stability of U6atac
Keywords: پلاسمایی قبل از mRNA; Mpn1; Poikiloderma with neutropenia; U6atac; Pre-mRNA splicing
hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron
Keywords: پلاسمایی قبل از mRNA; hnRNP L; Pre-mRNA splicing; CD44; V10 exon;
Exon 9 skipping of apoptotic caspase-2 pre-mRNA is promoted by SRSF3 through interaction with exon 8
Keywords: پلاسمایی قبل از mRNA; Caspase-2; SRSF3; Apoptotic; Anti-apoptotic; Pre-mRNA splicing; Exon 9
Imaging dynamic interactions between spliceosomal proteins and pre-mRNA in living cells
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; Spliceosome; Live cell imaging; Confocal microscopy; Fluorescence recovery after photobleaching; Photoactivation;
SRSF2 promotes splicing and transcription of exon 11 included isoform in Ron proto-oncogene
Keywords: پلاسمایی قبل از mRNA; Ron; Proto-oncogene; Pre-mRNA splicing; SRSF2; Transcription; Exon 11 inclusion;
The Supraspliceosome — A Multi-Task Machine for Regulated Pre-mRNA Processing in the Cell Nucleus
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; Riponucleoproteins (RNPs); U snRNPs; Alternative splicing; Intronic microRNA biogenesis; Suppression of splicing
Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells
Keywords: پلاسمایی قبل از mRNA; SRSF1; serine/arginine-rich splicing factor 1; PP1; protein phosphatase 1; GCS; glucosylceramide synthase; MBO-asGCS; mixed backbone oligonucleotide against glucosylceramide synthase; PDMP; d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; SMase;
hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7
Keywords: پلاسمایی قبل از mRNA; hnRNP M; Pre-mRNA splicing; Spinal muscular atrophy; SMN2; Exon 7;
The Mpn1 RNA exonuclease: Cellular functions and implication in disease
Keywords: پلاسمایی قبل از mRNA; Mpn1; Poikiloderma with neutropenia; U6 snRNA; Pre-mRNA splicing; RNA stability; RNA quality control;
SRp20: An overview of its role in human diseases
Keywords: پلاسمایی قبل از mRNA; AS; alternative splicing; PTM; post-translational modifications; RBDs; RNA-binding domains; RRM; RNA recognition motif; RS domain; domain rich in arginine and serine; snRNA; small nuclear RNA; snRNP; small nuclear RiboNucleoProtein; SR-proteins; serine/ar
Protein phosphatase 2A family members (PP2A and PP6) associate with U1 snRNP and the spliceosome during pre-mRNA splicing
Keywords: پلاسمایی قبل از mRNA; PP2A; PP6; Phosphatase; snRNPs; Pre-mRNA splicing;
Mechanistic insights into human pre-mRNA splicing of human ultra-short introns: Potential unusual mechanism identifies G-rich introns
Keywords: پلاسمایی قبل از mRNA; SSA; spliceostatin A; PAGE; polyacrylamide gel electrophoresis; ORF; open reading frame; ISE; intronic splicing enhancer; ESE; exonic splicing enhancer; Pre-mRNA splicing; Ultra-short intron; Intronic splicing enhancer; G-rich sequence; U snRNA; Spliceost
Identification of a novel cis-element that regulates alternative splicing of Bcl-x pre-mRNA
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; Bcl-x; Alternative splicing; Apoptosis; Exon inclusion; Exon skipping;
Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease
Keywords: پلاسمایی قبل از mRNA; Alternative splicing; Alzheimer's disease; Apoptosis; Calcium; Endoplasmic reticulum; Mild cognitive impairment; Pre-mRNA splicing; Ryanodine receptor;
G/A polymorphism in intronic sequence affects the processing of MAO-B gene in patients with Parkinson disease
Keywords: پلاسمایی قبل از mRNA; Monoamino oxidase B; Parkinson disease; Single nuclotide polymorphism (SNP); Pre-mRNA splicing; Splicesome; SR protein;
Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression
Keywords: پلاسمایی قبل از mRNA; NTC, nineteen complex; CSC, cell cycle and splicing complexBud31; Yeast; G1–S transition; Budding; Pre-mRNA splicing
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk)
Keywords: پلاسمایی قبل از mRNA; Clk1; Clk2; Clk3; Clk4; Dyrk1A; Dyrk1B; Pre-mRNA splicing; Kinase inhibition; Quinazoline
Potential therapeutic applications of antisense morpholino oligonucleotides in modulation of splicing in primary immunodeficiency diseases
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; Antisense morpholino oligonucleotides; Genetic disorders; Primary immunodeficiency diseases;
Role of the C. elegans U2 snRNP protein MOG-2 in sex determination, meiosis, and splice site selection
Keywords: پلاسمایی قبل از mRNA; MOG-2; Pre-mRNA splicing; Caenorhabditis elegans; Sex determination; Germ line; Meiosis
Knock-out mutations of Arabidopsis SmD3-b induce pleotropic phenotypes through altered transcript splicing
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; SmD3-a; SmD3-b; Knock out mutation; Pleotropic phenotypes
The RB/E2F pathway and regulation of RNA processing
Keywords: پلاسمایی قبل از mRNA; RB; Retinoblastoma tumor suppressor; E2F; RNA processing; Pre-mRNA splicing
Splice-site mutation c.313+1, G>A in intron 3 of the LDL receptor gene results in transcripts with skipping of exon 3 and inclusion of intron 3
Keywords: پلاسمایی قبل از mRNA; Familial hypercholesterolemia; LDL receptor; Mutation; mRNA; Pre-mRNA splicing
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk)
Keywords: پلاسمایی قبل از mRNA; Kinase inhibition; Pre-mRNA splicing; Clk; Dyrk1A
Arabidopsis thaliana PRP40s are RNA polymerase II C-terminal domain-associating proteins
Keywords: پلاسمایی قبل از mRNA; CTD, carboxyl-terminal domain; RNA polymerase II; RNA processing machineries; CTD phosphoarray; PCAPs, phospho-CTD-associated proteins; AtPRP40, arabidopsis thaliana PRE-mRNA-PROCESSING PROTEIN 40; Yeast two-hybrid assay; WW domains; pre-mRNA splicing; In
A mutation in teg-4, which encodes a protein homologous to the SAP130 pre-mRNA splicing factor, disrupts the balance between proliferation and differentiation in the C. elegans germ line
Keywords: پلاسمایی قبل از mRNA; Germline development; Stem cells; Proliferation; Pre-mRNA splicing; Tumor; Meiotic entry; Notch signaling; teg-4; tag-203; SAP130
Identification of a porcine DC-SIGN-related C-type lectin, porcine CLEC4G (LSECtin), and its order of intron removal during splicing: Comparative genomic analyses of the cluster of genes CD23/CLEC4G/DC-SIGN among mammalian species
Keywords: پلاسمایی قبل از mRNA; C-type lectins; CLEC4G (LSECtin); CD23; DC-SIGN (CD209); L-SIGN (CD209L); Pig; MicroRNA; Pre-mRNA splicing; Mammals
A Dentin Sialophosphoprotein Mutation That Partially Disrupts a Splice Acceptor Site Causes Type II Dentin Dysplasia
Keywords: پلاسمایی قبل از mRNA; Dentin; dentin dysplasia type II; dentinogenesis imperfecta; DSPP; pre-mRNA splicing;
Structure of the central RNA recognition motif of human TIA-1 at 1.95 Å resolution
Keywords: پلاسمایی قبل از mRNA; RRM; RNA binding domain; Pre-mRNA splicing; mRNA translation; TIA-1; TIAR
Factors associated with a purine-rich exonic splicing enhancer sequence in Xenopus oocyte nucleus
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; Exonic splicing enhancer; Xenopus oocyte;
Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants
Keywords: پلاسمایی قبل از mRNA; Pre-mRNA splicing; snRNP; snoRNP; Snu13p; Crystal structure
Increased expression of SRp40 affecting CD44 splicing is associated with the clinical outcome of lymph node metastasis in human breast cancer
Keywords: پلاسمایی قبل از mRNA; Breast cancer; Lymph node metastasis; SR; CD44; Pre-mRNA splicing;
Structural Basis for the Bifunctionality of the U5 snRNP 52K Protein (CD2BP2)
Keywords: پلاسمایی قبل از mRNA; U5 snRNP; pre-mRNA splicing; crystal structure; bifunctionality; CD2-receptor binding protein
Human immunodeficiency virus type 1 Vpr interacts with spliceosomal protein SAP145 to mediate cellular pre-mRNA splicing inhibition
Keywords: پلاسمایی قبل از mRNA; Human immunodeficiency virus type 1 Vpr; Pre-mRNA splicing; SAP145
A kinetic-dynamic model for regulatory RNA processing
Keywords: پلاسمایی قبل از mRNA; Kinetic-dynamic model; Pre-mRNA splicing; FCEA; FC_adaptive