Keywords: مرگ سلولی برنامه ریزی شده 1; APC; allophycocyanin; aMEM; medium eagle alpha modification; ANOVA; one-way analysis of variance; BALF; bronchoalveolar lavage fluid; bFGF; basic fibroblast growth factor; BM-MSC; bone marrow-derived mesenchymal stem cell; Ccl; chemokine (C-C motif) ligan
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Keywords: مرگ سلولی برنامه ریزی شده 1; Small molecules; biologics; adverse effects mouth; BP; Bisphosphonates; EGFR; Epidermal growth factor receptor; FDA; Food and Drug Administration; HER2; Human epidermal growth factor receptor 2; HNSCC; Head and neck squamous cell carcinoma; mAbs; Monoclon
Keywords: مرگ سلولی برنامه ریزی شده 1; APC; Antigen presenting cells; CIMP; CpG island methylator phenotype; CIN; chromosomal instability; CRC; colorectal cancer; CTLA-4; cytotoxic T lymphocyte-associated protein 4; DAMPs; danger-associated molecular patterns; FDA; US Food and Drug Administr
Keywords: مرگ سلولی برنامه ریزی شده 1; DC; dendritic cell; tolDCs; tolerogenic dendritic cells; PD-1; programmed cell death 1; PD-L1/PD-L2; programmed cell death ligand 1/2; 17XNL; nonlethal 17X strains; BCG; Mycobacterium bovis Bacillus Calmette Guérin; BMDCs; bone marrow-derived dendritic c
Keywords: مرگ سلولی برنامه ریزی شده 1; programmed cell death 1; immunohistochemistry; harmonization; nivolumab;
Keywords: مرگ سلولی برنامه ریزی شده 1; AP-1; activating protein 1; APC; antigen presenting cell; CAR; chimeric antigen receptors; Cbl-b; casitas B-lineage lymphoma; DAG; diacylglycerol; cSMAC; central supramolecular activation cluster; CTLA4; cytotoxic T lymphocyte antigen 4; dSMAC; distal sup
Keywords: مرگ سلولی برنامه ریزی شده 1; NSCLC; non-small cell lung cancer; irAE; immune-related adverse events; IIP; idiopathic interstitial pneumonia; UIP; usual interstitial pneumonia; PD-1; programmed cell death 1; ILD; interstitial lung disease; AE-IIP; acute exacerbation of idiopathic inte
Keywords: مرگ سلولی برنامه ریزی شده 1; EMG; electromyographic examination; IV; intravenous; MRI; magnetic resonance imaging; NCS; nerve conduction study; PD-1; programmed cell death 1; PD-L1; programmed cell death ligand 1; PET; positron emission tomography;
Keywords: مرگ سلولی برنامه ریزی شده 1; CTLA-4; cytotoxic T-lymphocyte-associated protein 4; ICI; immune checkpoint inhibitor; irAE; immune-related adverse event; mRSS; modified Rodnan skin score; PD-1; programmed cell death 1; PD-L1; programmed cell death ligand 1; RNAP3; RNA polymerase III;
Keywords: مرگ سلولی برنامه ریزی شده 1; immune therapy; metastatic melanoma; targeted therapy; APC; antigen presenting cells; BRAF; v-RAF murine sarcoma viral oncogene; CRR; complete response rate; CTLA-4; cytotoxic T-lymphocyte-associated antigen 4; irAEs; immune related adverse events; KA;
Keywords: مرگ سلولی برنامه ریزی شده 1; TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: مرگ سلولی برنامه ریزی شده 1; Immune checkpoint inhibitors; Immunotherapy; Programmed cell death 1; Programmed cell death receptor ligand 1; Cytotoxic T lymphocyte-associated protein 4; Urothelial cell cancer; Renal cell cancer; Prostate cancer; Urological cancer;
Keywords: مرگ سلولی برنامه ریزی شده 1; Programmed cell death 1; PD-1; PDCD1; anti-PD-1 antibody; PD-1 inhibitor; nivolumab; pembrolizumab; acute interstitial nephritis (AIN); acute kidney injury (AKI); non-small cell lung cancer (NSCLC); advanced melanoma; ipilimumab; immune checkpoint inhib
Keywords: مرگ سلولی برنامه ریزی شده 1; CRC; colorectal cancer; SNP; single nucleotide polymorphism; CNV; copy number variant; GWAS; genome-wide association studies; GO; gene ontology; BP; biological process; CAM; cell adhesion molecule; CIN; chromosomal instability; MSI; microsatellite instabi
Keywords: مرگ سلولی برنامه ریزی شده 1; Melanoma; Liquid biopsy; Circulating tumor cells; Cell-free circulating tumor DNA; Cell-free DNA; Cell-free microRNA; Ab; antibody; AIM1; absent in melanoma-1; AJCC; American Joint Committee on Cancer; BRAF; B-Raf proto-oncogene, serine/threonine kinase;
Keywords: مرگ سلولی برنامه ریزی شده 1; Epigenetic dynamics; Immune system; Autoimmune diseases; DNA methylation; Histone modifications; DNMT; DNA methyltransferase; TET; ten-eleven translocation; AID/AICDA; activation-induced cytidine deaminase; APOBEC; Apolipoprotein B mRNA editing enzyme; BE
Keywords: مرگ سلولی برنامه ریزی شده 1; AA; abiraterone acetate; ADT; androgen deprivation therapy; AR; androgen receptor; AR-V; AR splice variant; CRPC; castration-resistant prostate cancer; CTC; circulating tumor cell; CYP; cytochrome P450; FDA; Food and Drug Administration; LBD; ligand-bindi
Keywords: مرگ سلولی برنامه ریزی شده 1; Radiation; Immunotherapy; Dose; Fractionation; MHC-I; major histocompatibility class I; ICAM-1; intercellular adhesion molecules-1; CEA; carcinoembryonic antigen; CTL; cytotoxic T cells; CTLA-4; cytotoxic T-lymphocyte-associated antigen 4; gp 100; glycopr
A novel mouse model for tracking the fate of CXCR5-expressing T cells
Keywords: مرگ سلولی برنامه ریزی شده 1; Follicular helper T cells; CXCR5; Memory T cells; Humoral immunity; GC; Germinal center; Tfh; Follicular helper T; OVA; Ovalbumin; CXC-R5; C-X-C chemokine receptor type 5; CCR7; C-C chemokine receptor type 7; ICOS; Inducible costimulator; PD-1; Programmed
Expression of programmed cell death 1/programmed cell death ligand 1 in the tumor microenvironments of primary gastrointestinal diffuse large B cell lymphomas
Keywords: مرگ سلولی برنامه ریزی شده 1; Programmed cell death 1; Programmed cell death ligand 1; Expression; Gastrointestinal diffuse large B cell lymphoma;
Recent Developments in Oncology Immunotherapy, Implications for NPs Part 1
Keywords: مرگ سلولی برنامه ریزی شده 1; cytotoxic T-lymphocyte antigen 4; immune checkpoint inhibitor; immune-related adverse event; immunotherapy; nurse practitioner; programmed cell death 1; programmed death-ligand 1;
Docetaxel Down-Regulates PD-1 Expression via STAT3 in T Lymphocytes
Keywords: مرگ سلولی برنامه ریزی شده 1; Chemotherapy; Immune inhibition; Lung adenocarcinoma; Programmed cell death 1; Signal transduction and activator of transcription 3;
Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?
Keywords: مرگ سلولی برنامه ریزی شده 1; Cyclophosphamide (PubChem CID: 2907); DTIC (Dacarbazine) (PubChem CID: 5353562); GPI 15427 (PubChem CID: 11739525); Lomeguatrib (PubChem CID: 3025944); NU 1025 (PubChem CID: 63306); Temozolomide (PubChem CID: 5394); BER; base excision repair; CD2F1; hybri
HDAC inhibitors as epigenetic regulators for cancer immunotherapy
Keywords: مرگ سلولی برنامه ریزی شده 1; AICD; activation-induced cell death; AML; acute myeloid leukemia; APC; antigen-presenting cells; CAR; coxsackie- and adenovirus receptor; CDKs; cyclin-dependent kinases; CG; cancer germline; DCs; dendritic cells; HAT; histone acetyltransferase; HDAC; hist
DNA mismatch repair in cancer
Keywords: مرگ سلولی برنامه ریزی شده 1; 5-FU; 5-fluorouracil; bMMRD; Biallelic mismatch repair deficiency; CD28; cluster of differentiation 28; CIN; Chromosomal instable; CR; complete response; CRC; colorectal cancer; CTL; cytotoxic T-lymphocytes; CTLA-4; cytotoxic T lymphocyte antigen-4; DFS;
Hypoxia and HIF pathway in cancer and the placenta
Keywords: مرگ سلولی برنامه ریزی شده 1; Oxygen; Hypoxia-inducible factor; Placenta; Trophoblast; Cancer; CCRCC; clear cell renal cell carcinoma; FasL; Fas ligand; FIH; factor inhibiting HIF; FLT1; fms-related tyrosine kinase 1; HIF; hypoxia-inducible factor; HLA; human leukocyte antigen; MHC; m
Mini-reviewThe microbiome and hepatobiliary-pancreatic cancers
Keywords: مرگ سلولی برنامه ریزی شده 1; Bacteria; Cholangiocarcinoma; Gut-liver axis; Hepatocellular carcinoma; Pancreatic adenocarcinoma; HCC; hepatocellular carcinoma; NASH; non-alcoholic steatohepatitis; PDCD1; programmed cell death 1; ROS; reactive oxygen species; RYGB; Roux-en-Y gastric
Achaete-scute complex homologue 2 accelerates the development of Sjögren's syndrome-like disease in the NOD/ShiLtJ mouse
Keywords: مرگ سلولی برنامه ریزی شده 1; SS; Sjögren's syndrome; Ascl2; achaete-scute complex homologue 2; TFH; Follicular helper T cell; CXCR; C-X-C chemokine receptor; IL; interleukin; TNF; tumor necrosis factor; PD-1; programmed cell death 1; ICOS; inducible T-cell costimulator; BAFF; B-ce
Smoking activates cytotoxic CD8+ T cells and causes survivin release in rheumatoid arthritis
Keywords: مرگ سلولی برنامه ریزی شده 1; Rheumatoid arthritis; Survivin; Smoking; CD8+ T cells; Programmed cell death 1; Interleukin-7 receptor;
Management of Muscle-Invasive Urothelial Cancer and the Emerging Role of Immunotherapy in Advanced Urothelial Cancer
Keywords: مرگ سلولی برنامه ریزی شده 1; AKT; AKT serine/threonine kinase 1; BCG; bacillus Calmette-Guérin; CTLA4; cytotoxic T-lymphocyte-associated protein 4; EGFR; epidermal growth factor receptor; FDA; Food and Drug Administration; FGFR; fibroblast growth factor receptor; GC; gemcitabine p
Polymorphism in programmed cell death 1 gene is strongly associated with lung and kidney allograft survival in recipients from CMV-positive donors
Keywords: مرگ سلولی برنامه ریزی شده 1; cytomegalovirus; kidney transplantation; lung transplantation; programmed cell death 1; polymorphism; graft survival; clonal exhaustion;
Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas
Keywords: مرگ سلولی برنامه ریزی شده 1; Immunotherapy; GPC3; MAGEC2; Galectin 9; APC; antigen-presenting cells; BTLA; BÂ and T lymphocyte attenuator; CFSE; carboxyfluorescein diacetate succinimidyl ester; CTL; cytotoxic T cells; CTLA4; cytotoxic T-lymphocyte associated protein 4; GAL-9; galecti
PD-L1 expression is associated with epithelial-to-mesenchymal transition in adenocarcinoma of the lung
Keywords: مرگ سلولی برنامه ریزی شده 1; Programmed cell death 1; Programmed cell death 1 ligand 1; Epithelial-mesenchymal transition; Adenocarcinoma of the lung; Immune checkpoint; Cancer immunotherapy
Interleukin (IL)-24 transforms the tumor microenvironment and induces anticancer immunity in a murine model of colon cancer
Keywords: مرگ سلولی برنامه ریزی شده 1; IL-24; interleukin-24; PBMCs; peripheral blood mononuclear cells; MDA; melanoma differentiation-associated gene; IFN-γ; interferon-α; CTLA4; cytotoxic T-lymphocyte-associated protein 4; PD1; programmed cell death 1; TILs; tumor infiltrating lymphocytes;
Research ArticleEffector T cell function rather than survival determines extent and duration of hepatitis in mice
Keywords: مرگ سلولی برنامه ریزی شده 1; Alb; albumin; B6; C57BL/6; CFSE; carboxyfluorescein succinimidyl ester; CTL; cytotoxic T lymphocyte; LN; lymph node(s); Met; metallothionein; PD-1; programmed cell death 1; PD-L1; programmed cell death-ligand 1; RAG; recombination-activating genes; SOCS-1
Antitumor dendritic cell-based vaccines: lessons from 20Â years of clinical trials and future perspectives
Keywords: مرگ سلولی برنامه ریزی شده 1; APCs; antigen-presenting cells; cDCs; classical DCs; CTLs; cytotoxic T cells; CTLA-4; cytotoxic T-lymphocyte-associated antigen 4; DC; dendritic cell; Dex; dendritic cell-derived exosomes; EMA; European Medicines Agency; FDA; Food and Drug Administratio
Mechanisms of allergy and clinical immunologyHuman B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures
Keywords: مرگ سلولی برنامه ریزی شده 1; B cell; T-cell plasticity; IL-21; IFN-γ; coexpression; T-bet; Bcl-6; antibody response; crosstalk; Bcl-6; B cell lymphoma 6; DC; Dendritic cell; DP; Double positive; ICOS; Inducible costimulator; LN; Lymph node; PD-1; Programmed cell death 1; PE; Phycoer
Clinicopathological analysis of PD-L1 and PD-L2 expression in pulmonary squamous cell carcinoma: Comparison with tumor-infiltrating T cells and the status of oncogenic drivers
Keywords: مرگ سلولی برنامه ریزی شده 1; CD274; Programmed cell death 1 ligand 2; Programmed cell death 1; Squamous cell carcinoma of the lung; MET; Immunotherapy;
Skin dendritic cells induce follicular helper T cells and protective humoral immune responses
Keywords: مرگ سلولی برنامه ریزی شده 1; Steady-state conditions; skin dendritic cells; T follicular helper cells; protective humoral immune responses; CFA; Complete Freund adjuvant; CFSE; Carboxyfluorescein succinimidyl ester; DC; Dendritic cell; EAE; Experimental autoimmune encephalomyelitis;
The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma
Keywords: مرگ سلولی برنامه ریزی شده 1; melanoma; MPDL3280A; nivolumab; PD-1; PD-L1; pembrolizumab; pidilizumab; programmed cell death 1;
Epithelial CaSR deficiency alters intestinal integrity and promotes proinflammatory immune responses
Keywords: مرگ سلولی برنامه ریزی شده 1; CaSR; calcium-sensing receptor; IBD; inflammatory bowel disease; DCs; dendritic cells; TJ; tight junction; AJ; adherens junction; PRRs; pattern recognition receptors; GI; gastrointestinal; DSS; dextran sulfate sodium; TEER; transepithelial electrical resi
Programmed cell death 1 (PD-1) regulates the effector function of CD8 T cells via PD-L1 expressed on target keratinocytes
Keywords: مرگ سلولی برنامه ریزی شده 1; Programmed cell death 1; Programmed cell death ligand 1; Fas; Keratinocyte; CD8 T cell; Graft-versus-host-diseaseK14-mOVA mouse, keratin 14 promoter-membrane ovalbumin-transgenic mouse; GVHD, graft-versus-host disease; DTg mouse, K14-mOVA/OT-I double tran
Tolerogenic signaling by pulmonary CD1c+ dendritic cells induces regulatory T cells in patients with chronic obstructive pulmonary disease by IL-27/IL-10/inducible costimulator ligand
Keywords: مرگ سلولی برنامه ریزی شده 1; Chronic obstructive pulmonary disease; dendritic cells; regulatory T cells; IL-27; IL-10; inducible costimulator ligand; AHR; Aryl hydrocarbon receptor; APC; Antigen-presenting cell; BAL; Bronchoalveolar lavage; CD1c+DCCOPD; CD1c+ DCs from lung samples ob
Dysregulated Generation of Follicular Helper T Cells in the Spleen Triggers Fatal Autoimmune Hepatitis in Mice
Keywords: مرگ سلولی برنامه ریزی شده 1; Autoimmune Liver Disease; Pathogenesis; Follicular Helper T Cells; AIH; autoimmune hepatitis; ANA; antinuclear antibody; APC; allo-phycocyanin; CXCR; CXC chemokine receptor; EAE; experimental autoimmune encephalomyelitis; GC; germinal center; ICOS; induci