Prostaglandin D2 induces the production of human β-defensin-3 in human keratinocytes
Keywords: پروستاگلاندین D2; Prostaglandin D2; CRTH2; Human β-defensin-3; Keratinocyte; c-Fos
مقالات ISI پروستاگلاندین D2 (ترجمه نشده)
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CD203c expression on human basophils is associated with asthma exacerbation
Keywords: پروستاگلاندین D2; Airway inflammation; asthma exacerbation; basophil activation; basophil surface marker; biomarker; CD203c; ENO; Exhaled nitric oxide; MFI; Mean fluorescence intensity; PEF; Peak expiratory flow; PGD2; Prostaglandin D2; 15R-MePGD2; 15(R)-methyl prostagland
Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer
Keywords: پروستاگلاندین D2; 17β-Hydroxysteroid dehydrogenase; Prostaglandin F synthase; Prostaglandin D2; Estrogen receptor; Peroxisome proliferator activated receptor γ
Complement C5a stimulates food intake via a prostaglandin D2- and neuropeptide Y-dependent mechanism in mice
Keywords: پروستاگلاندین D2; Complement C5a; COX-2; Prostaglandin D2; DP1 receptor; Neuropeptide Y (NPY); Y1 receptor; Food intake; Central nervous system
Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells
Keywords: پروستاگلاندین D2; Osteoblasts; Inorganic phosphate transport; Prostaglandin D2
Induction of lipocalin-type prostaglandin D synthase in mouse heart under hypoxemia
Keywords: پروستاگلاندین D2; Prostaglandin D synthase; Heme oxygenase; Hypoxia; Prostaglandin D2; Lung; Heart; Pulmonary venous myocardium;
7-Azaindole-3-acetic acid derivatives: Potent and selective CRTh2 receptor antagonists
Keywords: پروستاگلاندین D2; CRTh2; Prostaglandin D2; Azaindole; Eosinophils; Allergic diseases
Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitis
Keywords: پروستاگلاندین D2; CRTH2; DP2; Prostaglandin D2; Antagonist; Allergic rhinitis; Mouse sneeze; Binding; Eosinophil; Shape change; Azaindole
Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia
Keywords: پروستاگلاندین D2; cerebral ischemia; middle cerebral artery occlusion; mouse; prostaglandins; PGD2; CBF; cerebral blood flow; COX; cyclooxygenase; H-PGDS; hematopoietic prostaglandin D synthase; L-PGDS; lipocalin-type prostaglandin D synthases; MABP; mean arterial blood pr
Secreted phospholipases A2: A proinflammatory connection between macrophages and mast cells in the human lung
Keywords: پروستاگلاندین D2; AA; arachidonic acid; Akt; protein kinase B; BA; bronchial asthma; BAL; bronchoalveolar lavage; BBMCs; bone marrow-derived mast cells; COPD; chronic obstructive pulmonary disease; ERK1/2; extracellular-regulated kinase 1/2; HSPG; heparan sulfate proteogly
Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis
Keywords: پروستاگلاندین D2; Prostaglandin D receptor gene promoter; asthma susceptibility; airway disease; montelukast; AE; Adverse experience; AR; Allergic rhinitis; CRTH2; Chemoattractant receptor-homologous molecule on T-helper type 2 cells, also known as DP2; DASS; Daytime Asthm
Central prostaglandins in food intake regulation
Keywords: پروستاگلاندین D2; Food intake; Prostaglandin E2; EP4 receptor; Prostaglandin D2; DP1 receptor; Neuropeptide;
Pharmacokinetics of recombinant human lipocalin-type prostaglandin D synthase/β-trace in canine
Keywords: پروستاگلاندین D2; Prostaglandin D2; Intrathecal injection; Intravenous injection; Serum; Cerebrospinal fluid; Urinary excretion rate;
Prostaglandin D2 induces heme oxygenase-1 mRNA expression through the DP2 receptor
Keywords: پروستاگلاندین D2; Cadmium; DP2 receptor; Heme oxygenase; Macular degeneration; Malaria; Prostaglandin D2; Retina; Stress
Prostaglandin D2 induces contraction via thromboxane A2 receptor in rat liver myofibroblasts
Keywords: پروستاگلاندین D2; Liver myofibroblast; Prostaglandin D2; Contraction; Thromboxane A2 receptor
Prostaglandin D2 induces heme oxygenase-1 in human retinal pigment epithelial cells
Keywords: پروستاگلاندین D2; Brain; Erythrocyte; Heme; Heme oxygenase; Iron; Malaria; Plasmodium falciparum; Prostaglandin D2; Retina;
Lipocalin-type prostaglandin D synthase is a powerful biomarker for severity of stable coronary artery disease
Keywords: پروستاگلاندین D2; Lipocalin-type prostaglandin D synthase; Prostaglandin D2; Coronary artery disease; Atherosclerosis; Biomarker
Inhibition of FcεRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement
Keywords: پروستاگلاندین D2; Siglec; mast cell; immunoreceptor tyrosine-based inhibitory motif; histamine; prostaglandin D2; IgE receptor; IRS; Inhibitory receptor superfamily; ITIM; Immunoreceptor tyrosine-based inhibitory motif; PGD2; Prostaglandin D2; SHP; src homology domain 2-
Exogenous nitric oxide regulates cyclooxygenase-2 expression and prostaglandin D2 generation through p38 MAPK in mouse bone marrow-derived mast cells
Keywords: پروستاگلاندین D2; Mast cells; Nitric oxide; Lipid mediators; Cyclooxygenase-1; Cyclooxygenase-2; Prostaglandin D2; Interleukin-6Act D, actinomycin D; ARE, AU-rich element; BMMC, mouse bone marrow-derived mast cell; cAMP, cyclic AMP; COX, cyclooxygenase; CREB, cAMP response
7β-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes
Keywords: پروستاگلاندین D2; Inflammation; Prostaglandin E2; Prostaglandin D2; 15-deoxy-prostaglandin-Δ12,14-J2; DHEA; PPAR-γ
Pharmacological and Functional Characterization of Novel EP and DP Receptor Agonists: DP1 Receptor Mediates Penile Erection in Multiple Species
Keywords: پروستاگلاندین D2; Prostaglandin D2; Prostaglandin E1; Organ Bath;
Extended-Release Niacin/Laropiprant: Reducing Niacin-Induced Flushing to Better Realize the Benefit of Niacin in Improving Cardiovascular Risk Factors
Keywords: پروستاگلاندین D2; Cardiovascular risk; Extended-release niacin; Flushing; Laropiprant; Prostaglandin D2
2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists
Keywords: پروستاگلاندین D2; CRTh2; Prostaglandin D2; Phenoxyacetic acid; Eosinophils; Allergic diseases
Synthesis and in vitro evaluation of a selective antagonist and the corresponding radioligand for the prostaglandin D2 receptor CRTH2
Keywords: پروستاگلاندین D2; CRTH2; DP2; Prostaglandin D2; 7TM receptor; GPCR; Antagonist; Radioligand
Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats
Keywords: پروستاگلاندین D2; Nasal symptom; Sneezing; Nasal rubbing; Histamine; Prostaglandin D2; CRTH2 (chemoattractant receptor-homologous molecule expressed on TH2 cells); Chlorpheniramine; Cyproheptadine; BW A868C; Ramatroban
Nicotinic acid induces secretion of prostaglandin D2 in human macrophages: An in vitro model of the niacin flush
Keywords: پروستاگلاندین D2; Nicotinic acid; Niacin; Flush; Prostaglandin D2; Dyslipidemia
Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains
Keywords: پروستاگلاندین D2; Hypoxic-ischemic encephalopathy; Neonate; Prostaglandin D2; Lipocalin-type prostaglandin D synthase; Apoptosis
Involvement of chemical mediators in nasal allergic responses of HDC-KO mice
Keywords: پروستاگلاندین D2; Nasal allergic response; Sneezing; Nasal rubbing; Histamine; Prostaglandin D2; Chlorpheniramine; L-733,060; BW A868C; HDC (histidine decarboxylase) knockout mice; C57BL/6
The anti-pruritic efficacy of TS-022, a prostanoid DP1 receptor agonist, is dependent on the endogenous prostaglandin D2 level in the skin of NC/Nga mice
Keywords: پروستاگلاندین D2; Atopic dermatitis; TS-022; NC/Nga mouse; Prostaglandin D2; Scratching
Focal cerebral ischemia/reperfusion injury in mice induces hematopoietic prostaglandin D synthase in microglia and macrophages
Keywords: پروستاگلاندین D2; PGD2; PGDS; microglia/macrophage; inflammation; ischemic stroke; tissue repair; COX; cyclooxygenase; EGFP; enhanced green fluorescent protein; GFAP; glial fibrillary acidic protein; GST-Ï; glutathione S-transferase-pi; H-PGDS; hematopoietic prostaglandin
Cooperative activation of lipocalin-type prostaglandin D synthase gene expression by activator protein-2β in proximal promoter and upstream stimulatory factor 1 within intron 4 in human brain-derived TE671 cells
Keywords: پروستاگلاندین D2; PG; prostaglandin; L-PGDS; lipocalin-type PGD synthase; AP; activator protein; USF; upstream stimulatory factor; UTR; untranslated region; EMSA; electrophoretic mobility shift assay; ChIP; chromatin immunoprecipitation; siRNA; small interference RNA; N.C.
Expression and biological role of the prostaglandin D synthase/SOX9 pathway in human ovarian cancer cells
Keywords: پروستاگلاندین D2; SOX9; Prostaglandin D2; Ovarian tumor; Proliferation; Apoptosis
Modulation of Macrophage Nitric Oxide Production by Prostaglandin D2
Keywords: پروستاگلاندین D2; prostaglandin D2; nitric oxide; sepsis; macrophages
Profiling of prostanoids in zebrafish embryonic development
Keywords: پروستاگلاندین D2; PG; prostanoid; COX; cyclooxygenase; PGD2; prostaglandin D2; PGE2; prostaglandin E2; PGF2α; prostaglandin F2α; PGI2; prostacyclin; TXA2; thromboxnae A2; hpf; hour post-fertilization; dpf; day post-fertilization; RT-PCR reverse transcription-polymerase cha
Successful treatment of eosinophilic otitis media using ramatroban: Report of two cases
Keywords: پروستاگلاندین D2; Eosinophilic otitis media; Nasal polyp; Aspirin-induced asthma; IL-5; Prostaglandin D2; 11-Dehydro-thromboxane B2;
Identification of an indole series of prostaglandin D2 receptor antagonists
Keywords: پروستاگلاندین D2; Prostaglandin D2; PGD2; DP receptor antagonist; Indole
Functional characterization of human mast cells cultured from adult peripheral blood
Keywords: پروستاگلاندین D2; Anti-asthmatics; Peripheral blood; Cultured mast cells; Histamine; Prostaglandin D2; Cysteinyl-leukotrienes
Lipocalin-type prostaglandin D synthase as a melanocyte marker regulated by MITF
Keywords: پروستاگلاندین D2; Lipocalin-type prostaglandin D synthase; Melanocyte; Melanoma; Microphthalmia-associated transcription factor; Prostaglandin D2; skin
Strategies for targeting T-cells in allergic diseases and asthma
Keywords: پروستاگلاندین D2; AHR; airway hyperreactivity; AP; activator protein; APC; antigen-presenting cell; BAL; bronchoalveolar lavage; cAMP; cyclic adenosine monophosphate; CBP; CREB-binding protein; CpG DNA; CpG-containing immunostimulatory deoxyribonucleic acid; CsA; cyclospor
Synthesis of 15R-PGD2: a potential DP2 receptor agonist
Keywords: پروستاگلاندین D2; Prostaglandin D2; 15R-PGD2; 15R-PGE2; DP2 receptor; Eosinophils;
Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists
Keywords: پروستاگلاندین D2; CRTH-2; Prostaglandin D2; Ramatroban; Asthma;
Endogenous prostaglandin D2 synthesis decreases vascular cell adhesion molecule-1 expression in human umbilical vein endothelial cells
Keywords: پروستاگلاندین D2; Prostaglandin D2; Prostaglandin D2 synthase; Vascular cell adhesion molecule-1; Gene transfer;
Links between the innate immune system and sleep
Keywords: پروستاگلاندین D2; Sleep; infection; innate immunity; virus; bacteria; toll-like receptors; cytokines; circadian rhythms; stress; asthma; APR; Acute-phase response; dsRNA; Double-stranded RNA; EEG; Electroencephalographic; GHRH; Growth hormone-releasing hormone; NK cells;
The endogenous somnogen adenosine excites a subset of sleep-promoting neurons via A2A receptors in the ventrolateral preoptic nucleus
Keywords: پروستاگلاندین D2; rat; VLPO; arousal; sleep factor; serotonin; A1R; A1 adenosine receptors; A2AR; A2A adenosine receptors; ACSF; artificial cerebrospinal fluid; AHP; afterhyperpolarization; CGS21680; 2-[p-(carboxyethyl)-phenylethylamino]-5â²-N-ethylcarboxyamidoadenosine;
Î12-Prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes
Keywords: پروستاگلاندین D2; CRTH2; chemoattractant receptor-homologous molecule expressed on Th2 cells; Dk-PGD2; 13,14-dihydro-15-keto-PGD2; DP; D prostanoid receptor; GPCR; G protein-coupled receptor; 15d-PGD2; 15-deoxy-Î12,14PGD2; PGD2; prostaglandin D2; PTX; Bordella pertussis t