Keywords: تخریب پروتئازوما; Glycoprotein folding; Endoplasmic reticulum; Chaperones; Calnexin; Calreticulin; Glucosyltransferase; Proteasomal degradation;
مقالات ISI تخریب پروتئازوما (ترجمه نشده)
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Keywords: تخریب پروتئازوما; Ataxin-2; Cdk5; SCA2; Phosphorylation; Proteasomal degradation; PolyQALS, amyotrophic lateral sclerosis; Cdk5, cyclin-dependent kinase 5; HD, Huntington's disease; htt, huntingtin; SCA, spinocerebellar ataxia; SDS-PAGE, sodium dodecyl sulfate polyacrylami
Keywords: تخریب پروتئازوما; bHLH; basic Helix-Loop-Helix; Ngn2; Neurogenin 2; UPS; Ubiquitin-Proteasome System; Ub; ubiquitin; ANOVA; analysis of variance; UD; unfolded domain; Xenopus; Ubiquitylation; Neurogenesis; Proneural; Proteasomal degradation;
Discovery of bicyclo[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors
Keywords: تخریب پروتئازوما; Hypoxia inducible factor (HIF)-1α; Inhibitor; Transcriptional activity; Proteasomal degradation;
E3 ubiquitin ligase HECW2 mediates the proteasomal degradation of HP1 isoforms
Keywords: تخریب پروتئازوما; E3 ligase HECW2; HP1α, β and γ; Ubiquitination; Proteasomal degradation; Lamins; Laminopathies;
CRL4BRBBP7 targets HUWE1 for ubiquitination and proteasomal degradation
Keywords: تخریب پروتئازوما; HUWE1; CUL4B; RBBP7; Proteasomal degradation; Ubiquitination;
Regulating the regulators: Epigenetic, transcriptional, and post-translational regulation of RGS proteins
Keywords: تخریب پروتئازوما; Regulator of G protein signaling; RGS; Epigenetics; Transcription factors; Post-translational modification; MicroRNA; Proteasomal degradation; Therapeutics;
Methyl-2-acetylamino-3-(4-hydroxyl-3,5-dimethoxybenzoylthio)propanoate suppresses melanogenesis through ERK signaling pathway mediated MITF proteasomal degradation
Keywords: تخریب پروتئازوما; Microphthalmia-associated transcription factor; ERK signaling pathway; Depigmentation; A reconstructed human skin tissue; Proteasomal degradation;
HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction
Keywords: تخریب پروتئازوما; HIV-1; Type 1 IFNs; JAK/STAT; Viral immune evasion; Proteasomal degradation; ISG;
E3 ubiquitin ligase HECW2 targets PCNA and lamin B1
Keywords: تخریب پروتئازوما; E3 ligase HECW2; Lamin A/C; Lamin B1; PCNA; Ubiquitination; Proteasomal degradation; Laminopathies;
Testin and filamin-C downregulation by acetylated Siah2 increases invasiveness of Helicobacter pylori-infected gastric cancer cells
Keywords: تخریب پروتئازوما; ac-lys; acetylated lysine; ac-Siah2; acetylated Siah2; ac-K139 Siah2; acetylated K139 Siah2; ASB2; a suppressor of cytokine signalling box 2 gene; cag; cytotoxin-associated gene; CHIP; C-terminus of Hsc70 interacting protein; DAPI; 4',6-Diamidino-2-phenyl
BCL11B is frequently downregulated in HTLV-1-infected T-cells through Tax-mediated proteasomal degradation
Keywords: تخریب پروتئازوما; B-cell leukemia/lymphoma 11B (BCL11B); Human T-cell leukemia virus type 1 (HTLV-1); Tax; Proteasomal degradation;
Parkin promotes proteasomal degradation of synaptotagmin IV by accelerating polyubiquitination
Keywords: تخریب پروتئازوما; Parkinson's disease; Syt IV; Proteasomal degradation; Polyubiquitination; Evoked exocytosis regulator;
Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation
Keywords: تخریب پروتئازوما; MCM7; Cep68; Centrosome splitting; Proteasomal degradation; Ubiquitination;
Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5
Keywords: تخریب پروتئازوما; Protein ubiquitination; Proteasomal degradation; E3 ligase; Smurf1; USP5;
USP15 stabilizes the transcription factor Nrf1 in the nucleus, promoting the proteasome gene expression
Keywords: تخریب پروتئازوما; Ubiquitination; Deubiquitination; Proteasomal degradation; Transcription factor; Gene regulation; ARE; antioxidant response element; CNC; Cap'n'Collar; DUB; deubiquitinating enzyme; ER; endoplasmic reticulum; NHB1; N-terminal homology box 1; Nrf1; NF-
Characterization of a mutant form of human apolipoprotein B (Thr26_Tyr27del) associated with familial hypobetalipoproteinemia
Keywords: تخریب پروتئازوما; Apo; apolipoprotein; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; FHBL; familial hypobetalipoproteinemia; HDL; high density lipoprotein; LDL; low density lipoprotein; PS; penicillin-streptomycin; VLDL; ve
Cdx2 represses Oct4 function via inducing its proteasome-dependent degradation in early porcine embryos
Keywords: تخریب پروتئازوما; Pig; Early embryo; Cdx2; Oct4; Molecular interaction; Proteasomal degradation;
F-box protein Fbxo3 targets Smurf1 ubiquitin ligase for ubiquitination and degradation
Keywords: تخریب پروتئازوما; Protein ubiquitination; Proteasomal degradation; Ubiquitin ligase; Fbxo3; Smurf1;
The E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stability
Keywords: تخریب پروتئازوما; Ubiquitination; Proteasomal degradation; WW domain; PPXY motif; Apoptosis
A Fas associated factor negatively regulates anti-bacterial immunity by promoting Relish degradation in Bombyx mori
Keywords: تخریب پروتئازوما; BmFAF; Negative regulation; Relish; Proteasomal degradation; Bombyx mori;
Inhibition of mTOR affects protein stability of OGT
Keywords: تخریب پروتئازوما; O-GlcNAc; OGT; Protein stability; Autophagy; mTOR inhibitor; Proteasomal degradation;
Dimethyl fumarate inhibits the expression and function of hypoxia-inducible factor-1α (HIF-1α)
Keywords: تخریب پروتئازوما; Hypoxia; Hypoxia-inducible factor-1α (HIF-1α); Heat shock protein 90 (Hsp90); The receptor of activated protein kinase C (RACK1); Proteasomal degradation
Transport of c-MYC by Kinesin-1 for proteasomal degradation in the cytoplasm
Keywords: تخریب پروتئازوما; RBL; rose bengal lactone; EHNA; erythro-9-[3-(2-hydroxynonyl)] adenine; LMB; leptomycin B; KLC1; Kinesin Light Chain 1; DMSO; dimethyl sulfoxide; HMWS; high molecular-weight species; DAPI; 4â²,6-diamidino-2-phenylindole; c-MYC; Kinesin-1; Trafficking; Pr
UCH-L1 induces podocyte hypertrophy in membranous nephropathy by protein accumulation
Keywords: تخریب پروتئازوما; Membranous nephropathy; Passive Heymann nephritis; Ubiquitin C-terminal hydrolase-L1; Proteasomal degradation; Hypertrophy; p27Kip1;
Critical lysine residues of Klf4 required for protein stabilization and degradation
Keywords: تخریب پروتئازوما; Oncogene; Proteasomal degradation; Tumor suppressor; Ubiquitin; Ubiquitination;
An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19
Keywords: تخریب پروتئازوما; USP19; SIAH1 ligase; SIAH degron; Proteasomal degradation;
Identification of ubiquitin-modified lysine residues and novel phosphorylation sites on eukaryotic initiation factor 2B epsilon
Keywords: تخریب پروتئازوما; DMEM; Dulbecco's modified Eagle's medium; eIF; eukaryotic initiation factor; HECT; homologous to E5-AP carboxyl terminus; LC; liquid chromatography; MS/MS; tandem mass spectrometry; NEDD4; neural precursor cell expressed, developmentally down-regulate
SIRT1 negatively regulates the protein stability of HIPK2
Keywords: تخریب پروتئازوما; SIRT1; HIPK2; Deacetylation; Ubiquitination; Proteasomal degradation;
Erythrocyte-based analgesic peptides
Keywords: تخریب پروتئازوما; Erythrocrine; Analgesic peptide; Erythrocyte; Hemoglobin; Proteasomal degradation; Hemorphin;
PTK6 promotes degradation of c-Cbl through PTK6-mediated phosphorylation
Keywords: تخریب پروتئازوما; c-Cbl; Oncoprotein; Phosphorylation; Proteasomal degradation; PTK6; UbiquitinBrk, breast tumor kinase; EGF, epidermal growth factor; HGF, hepatocyte growth factor; PDGF, platelet-derived growth factor; PR, proline-rich; PTK, protein tyrosine kinase; RTK,
Differential regulation of PML-RARα stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1
Keywords: تخریب پروتئازوما; APL; acute promyelocytic leukemia; ATRA; all-trans retinoic acid; HDACi; histone deacetylase inhibitor; PML-RARα; promyelocytic leukemia-retinoic acid receptor α; SIAH; seven in absentia homolog; TRIAD1; two RING fingers and DRIL (double RING finger
HIV-2 viral protein X (Vpx) ubiquitination is dispensable for ubiquitin ligase interaction and effects on macrophage infection
Keywords: تخریب پروتئازوما; Viral protein X; Vpx; Ubiquitination; Macrophage infection; Localization; HIV packaging; DCAF1; Proteasomal degradation
Janus kinase 2 - A novel negative regulator of estrogen receptor α function
Keywords: تخریب پروتئازوما; CA; constitutive active; CDK2; Cyclin dependent kinase 2; CDK7; Cyclin dependent kinase 7; CK2; Casein kinase 2; DCC; dextran-coated charcoal-treated; DNA-PK; DNA-dependent protein kinase; E2; 17β-estradiol; EGFR; Epidermal growth factor receptor; ER; es
RhoBTB3 interacts with the 5-HT7a receptor and inhibits its proteasomal degradation
Keywords: تخریب پروتئازوما; 5-HT7 receptor; RhoBTB3; Proteasomal degradation; Depression; Impulsive behavior;
Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma
Keywords: تخریب پروتئازوما; Skin Cancer; p53; Tumor suppressor; Proteasomal degradation; Ubiquitination; Proteasomal inhibitor MG132
Smurf1 ubiquitin ligase targets Kruppel-like factor KLF2 for ubiquitination and degradation in human lung cancer H1299 cells
Keywords: تخریب پروتئازوما; Protein ubiquitination; Proteasomal degradation; Ubiquitin ligase; KLF2; Smurf1
The C-terminus of Hsp70-Interacting Protein Promotes Met Receptor Degradation
Keywords: تخریب پروتئازوما; C-terminus of Hsp70-Interacting Protein (CHIP); Met; Proteasomal degradation; Ubiquitination
Interaction and co-localization of JC virus large T antigen and the F-box protein β-transducin-repeat containing protein
Keywords: تخریب پروتئازوما; JCV T antigen; βTrCP; β-catenin; Oncogenic potential; Proteasomal degradation;
Elongin C is a mediator of Notch4 activity in human renal tubule cells
Keywords: تخریب پروتئازوما; Notch signaling; TGF-beta; Proteasomal degradation; Ubiquitin ligase; Proteomics; Mass spectrometry;
Developmental downregulation of Xenopus cyclin E is phosphorylation and nuclear import dependent and is mediated by ubiquitination
Keywords: تخریب پروتئازوما; Xenopus laevis; Cyclin E; Midblastula transition; Phosphorylation; Proteasomal degradation; Ubiquitination
Homeodomain-interacting protein kinase 2 (HIPK2) targets β-catenin for phosphorylation and proteasomal degradation
Keywords: تخریب پروتئازوما; HIPK2; β-Catenin phosphorylation; Proteasomal degradation
Determinants of CREB degradation and KChIP2 gene transcription in cardiac memory
Keywords: تخریب پروتئازوما; Cardiac memory; cAMP response element binding protein; Angiotensin II; Reactive oxygen species; Ubiquitination; Proteasomal degradation; CREB; cyclic adenosine monophosphate response element binding protein; LA; left atrium/atrial; LAD; left anterior desc
Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis
Keywords: تخریب پروتئازوما; Rb; Human papillomavirus (HPV); E7; Proteasomal degradation; E2-25K; Ubiquitination; Cell cycle regulation;
NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
Keywords: تخریب پروتئازوما; Antioxidant response element (ARE); Benzene toxicity; Estrogen quinone; Keap1; Microtubule stability; Nrf2; Oxidative stress; p53; Proteasomal degradation
Small-molecule inhibitors of MDM2 as new anticancer therapeutics
Keywords: تخریب پروتئازوما; Cancer therapy; Drug discovery and development; MDM2 inhibitor; MDMX; Nongenotoxic p53 activation; Protein–protein interaction; E3 ubiquitin ligase inhibitor; Proteasomal degradation; Nutlin; Benzodiazepinedione; Spiro-oxindole
Intrinsic AhR function underlies cross-talk of dioxins with sex hormone signalings
Keywords: تخریب پروتئازوما; Dioxin receptor; AhR; Sex hormone receptor; Estrogen; Cross-talk; Transcription; Ubiquitin ligase; Proteasomal degradation
Cyclic stretch decreases TRPC4 protein and capacitative calcium entry in rat vascular smooth muscle cells
Keywords: تخریب پروتئازوما; Calcium; Capacitative calcium entry; Store-operated; Mechanical strain; Cyclic stretch; TRPC; Receptor-operated calcium entry; Proteasomal degradation
Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer
Keywords: تخریب پروتئازوما; APC, Adenomatous polyposis coli; GSK3β, glycogen synthase kinase 3βAtoh1; Hath1; Proteasomal degradation; Differentiation; Wnt; GSK3β; Colon cancer
Ubiquitin-dependent and -independent proteasomal degradation of hepatitis B virus X protein
Keywords: تخریب پروتئازوما; HBV; HBX; Proteasomal degradation; Ub-dependent; Ub-independent