Keywords: مهار پروتئازوم; Carfilzomib; Proteasome inhibition; Cardiotoxicity; Endothelial dysfunction;
مقالات ISI مهار پروتئازوم (ترجمه نشده)
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Keywords: مهار پروتئازوم; Multiple myeloma; Proteasome inhibition; PTH receptor;
Keywords: مهار پروتئازوم; Desensitization; Plasma cell; Donor specific antibody; Solid organ transplantation; Bortezomib; Proteasome inhibition;
Keywords: مهار پروتئازوم; Bortezomib; Peripheral neuropathy; Proteasome inhibition; Neurotoxicity; Nuclear factor kappa b; Sensory neurons
6-Shogaol induces caspase-independent paraptosis in cancer cells via proteasomal inhibition
Keywords: مهار پروتئازوم; 6S; 6-Shogaol; 6G; 6-Gingerol; MTT; 3-(4, 5-dimethylthiazol-2-yl)â2, 5-diphenyltetrazolium bromide; ER stress; Endoplasmic reticulum stress; UPR; Unfolded protein response; CHX; Cycloheximide; 3MA; 3 Methyl adenine; CQ; Chloroquine di phosphate; HBSS; H
A phase I pharmacokinetic study of intraperitoneal bortezomib and carboplatin in patients with persistent or recurrent ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study
Keywords: مهار پروتئازوم; Intraperitoneal; Ovarian cancer; Proteasome inhibition; Platinum;
Pharmacokinetics-directed Intravenous Busulfan Combined With High-dose Melphalan and Bortezomib as a Conditioning Regimen for Patients With Multiple Myeloma
Keywords: مهار پروتئازوم; Autologous stem cell transplant; High-dose chemotherapy; Personalized medicine; Proteasome inhibition; Targeted therapy;
The proteasome - victim or culprit in autoimmunity
Keywords: مهار پروتئازوم; Ubiquitin proteasome system; Proteasome-associated autoinflammatory syndromes; Interferonopathy; Autoimmune diseases; Proteasome inhibition;
Structural characterization, ROS-inductive and proteasome inhibitory properties of ternary and binary copper(II) complexes of N2- and N2O2-ligands
Keywords: مهار پروتئازوم; Copper complexes; Spin-spin interaction; Reactive oxygen species; Proteasome inhibition; Trypsin-like site selective inhibitor
Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload
Keywords: مهار پروتئازوم; CHF; congestive heart failure; PsmI; proteasome inhibition; CR-PsmI; cardiomyocyte-restricted PsmI; LV; left ventricle; NTG; non-transgenic; PFI; proteasome functional insufficiency; PQC; protein quality control; TAC; transverse aortic constriction; TG; t
Role of iron in UPS impairment model of Parkinson's disease
Keywords: مهار پروتئازوم; Iron homeostasis; UPS; Proteasome inhibition; Dopamine neuron degeneration; Parkinson's disease
Bortezomib for Refractory Autoimmunity in Pediatrics
Keywords: مهار پروتئازوم; Refractory autoimmunity; Autoimmune cytopenias; Bortezomib; Proteasome inhibition
A Phase II Study of Bortezomib Plus Prednisone for Initial Therapy of Chronic Graft-versus-Host Disease
Keywords: مهار پروتئازوم; Chronic graft-versus-host disease; Hematopoietic stem cell transplantation; Graft-versus-host disease; Proteasome inhibition
Baicalein attenuates proteasome inhibition-induced apoptosis by suppressing the activation of the mitochondrial pathway and the caspase-8- and Bid-dependent pathways
Keywords: مهار پروتئازوم; Baicalein (EMD-Calbiochem Pubchem CID 5281605); MG132 (Sigma-Aldrich Inc. CID 462382); MG115 (Sigma-Aldrich Inc. CID 9868928); TiterTACS⢠colorimetric apoptosis detection kit (TrevigenInc.); Assay kit for rat/mouse cytochrome c (R&D systems); Assay kits
The role of Src protein in the process formation of PC12 cells induced by the proteasome inhibitor MG-132
Keywords: مهار پروتئازوم; Cy3; Â a fluorophor cyanin dye; DMEM; Â Dulbecco's Modified Eagle's Medium; DMSO; Â dimethyl-sulfoxyde; EDTA; Â ethylenediaminetetraacetic acid; EGTA; Â ethylene glycol tetraacetic acid; ERK1/2; Â extracellular signal-regulated kinase 1 and 2; H-Ras;
Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway
Keywords: مهار پروتئازوم; Programmed cell death; Oxidative stress; Epoxomicin; Retinoic acid; SH-SY5Y cells; Ubiquitin; Proteasome inhibition; AKT;
Proteasome inhibition by bortezomib: Effect on HLA-antibody levels and specificity in sensitized patients awaiting renal allograft transplantation
Keywords: مهار پروتئازوم; AMR; antibody mediated rejection; ATG; antithymocyte globulin; CDC; complement-dependent lymphocytotoxic; HLA; human leucocyte antigen; Ig; immunoglobulin; IL; interleukin; IVIG; intravenous immunoglobulin; MFI; mean fluorescence intensity; PRA; panel rea
Probing chemical reduction in a cobalt(III) complex as a viable route for the inhibition of the 20S proteasome
Keywords: مهار پروتئازوم; HL1; 2,4-diiodo-6-((pyridine-2-ylmethylamino)methyl)phenol; CT; chymotrypsin; AA; ascorbic acid; HR-(+)-ESI-MS; high resolution electrospray ionization mass spectrometry in the positive mode; DFT; density functional theory; TD-DFT; time-dependent density
Proteasome inhibitor-based therapy for antibody-mediated rejection
Keywords: مهار پروتئازوم; antibody-mediated rejection; bortezomib; proteasome inhibition
Implication of Nrf2 and ATF4 in differential induction of CHOP by proteasome inhibition in thyroid cancer cells
Keywords: مهار پروتئازوم; Proteasome inhibition; CHOP; ATF4; Nrf2
Nuclear speckles are involved in nuclear aggregation of PABPN1 and in the pathophysiology of oculopharyngeal muscular dystrophy
Keywords: مهار پروتئازوم; Oculopharyngeal muscular dystrophy; Skeletal myofibers; Intranuclear inclusions; Nuclear speckles; Pre-mRNA processing; Poly(A)-binding protein nuclear 1; Nuclear body biogenesis; Proteasome inhibition
Randomized Phase II Trial of Concurrent Versus Sequential Bortezomib Plus Docetaxel in Advanced Non–Small-Cell Lung Cancer: A California Cancer Consortium Trial
Keywords: مهار پروتئازوم; Bortezomib; Docetaxel; Proteasome inhibition
Bortezomib for Patients with Advanced-Stage Bronchioloalveolar Carcinoma: A California Cancer Consortium Phase II Study (NCI 7003)
Keywords: مهار پروتئازوم; Bortezomib; Proteasome inhibition; BAC; Bronchioloalveolar carcinoma; NSCLC
Effects of tethered ligands and of metal oxidation state on the interactions of cobalt complexes with the 26S proteasome
Keywords: مهار پروتئازوم; Proteasome inhibition; Cobalt complexes; NMR spectroscopy; Cell apoptosis;
Prevention of diabetic nephropathy in rats through enhanced renal antioxidative capacity by inhibition of the proteasome
Keywords: مهار پروتئازوم; Proteasome inhibition; Oxidative stress; Antioxidant; Diabetic nephropathy
Antiatherogenic effect of quercetin is mediated by proteasome inhibition in the aorta and circulating leukocytes
Keywords: مهار پروتئازوم; bismethylspermine; multi-organ injury; proteasome inhibition; atherosclerosis; flavonoids;
A novel gallium compound synergistically enhances bortezomib-induced apoptosis in mantle cell lymphoma cells
Keywords: مهار پروتئازوم; Mantle cell lymphoma; Bortezomib; Gallium maltolate; Chemotherapy; Drug synergy; Proteasome inhibition; Apoptosis
A new tick Kunitz type inhibitor, Amblyomin-X, induces tumor cell death by modulating genes related to the cell cycle and targeting the ubiquitin-proteasome system
Keywords: مهار پروتئازوم; Apoptosis; Proteasome inhibition; Amblyomin-X; Tick; Amblyomma cajennense
Proteasome inhibition prevents experimentally-induced endothelial dysfunction
Keywords: مهار پروتئازوم; Endothelial dysfunction; Proteasome inhibition; Reactive oxygen species
Proteasome inhibition enhances antitumour effects of gemcitabine in experimental pancreatic cancer
Keywords: مهار پروتئازوم; pancreatic cancer; experimental therapy; proteasome inhibition; bortezomib combination therapy;
N-Terminal-prolonged vinyl ester-based peptides as selective proteasome β1 subunit inhibitors
Keywords: مهار پروتئازوم; Synthesis; Pseudopeptides; Proteasome inhibition; Post-acidic activity
Endoplasmic reticulum stress and autophagy as targets for cancer therapy
Keywords: مهار پروتئازوم; GRP78; BiP; CHOP; GADD153; SERCA; Misfolded proteins; Proteasome inhibition; Calcium imbalance; SERCA inhibition; HIV protease inhibitors; HDAC inhibitors; Bortezomib; Nelfinavir; Celecoxib; ER stress; Autophagy; Apoptosis; Combination therapy
Metals in anticancer therapy: Copper(II) complexes as inhibitors of the 20S proteasome
Keywords: مهار پروتئازوم; Proteasome inhibition; Anticancer therapy; Copper(II); Metallodrugs; Bioinorganic
Transcriptional upregulation of BAG3 upon proteasome inhibition
Keywords: مهار پروتئازوم; BAG3; Proteasome inhibition; Transcription; Apoptosis
Proteasome affects the expression of aryl hydrocarbon receptor-regulated proteins
Keywords: مهار پروتئازوم; Aryl hydrocarbon receptor; N-Acetyl-leucyl-leucyl-norleucinal; Proteasome inhibition; Down-regulation; Dioxin; T47D cell
Proteasomal inhibition stabilizes topoisomerase IIα protein and reverses resistance to the topoisomerase II poison ethonafide (AMP-53, 6-ethoxyazonafide)
Keywords: مهار پروتئازوم; Topoisomerase IIα; Proteasome inhibition; Multiple myeloma; Combination therapy;
Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IκBα
Keywords: مهار پروتئازوم; Proteasome inhibition; IκBα; Nuclear translocation; Prostate cancer; NFκB; Apoptosis
C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors
Keywords: مهار پروتئازوم; Constrained phenylalanine analogues; Synthesis; Pseudopeptides; Proteasome inhibition
TMC-95A–D and analogues: Chemistry and biology
Keywords: مهار پروتئازوم; Anticancer agents; Proteasome Inhibition; TMC-95; Macrocyclic Peptides; Natural Product Synthesis; Natural Product AnaloguesAnticancéreux; Inhibition du Protéasome; TMC-95; Peptides Macrocycliques; Synthèse de Produits Naturels; Analogues de Produits Natu
Proteasomal inhibition in intracerebral hemorrhage: Neuroprotective and anti-inflammatory effects of bortezomib
Keywords: مهار پروتئازوم; Bortezomib; Proteasome inhibition; Ubiquitin-proteasome system (UPS); Intracerebral hemorrhage; Apoptosis; Inflammation
Hsp70-GlcNAc-binding activity is released by stress, proteasome inhibition, and protein misfolding
Keywords: مهار پروتئازوم; Hsp70; Stress; O-GlcNAc; UDP-GlcNAc; Energy charge; Proteasome inhibition; Amino-acid analogue;
Adaptive modification and flexibility of the proteasome system in response to proteasome inhibition
Keywords: مهار پروتئازوم; Proteasome; Proteasome inhibition; Proteasome inhibitor; Tripeptidyl peptidase II; Adaptive modification; Apoptosis resistance
Dendritic Cell Maturation Stage Determines Susceptibility to the Proteasome Inhibitor Bortezomib
Keywords: مهار پروتئازوم; Dendritic cells; maturation; proteasome inhibition; NF-κB
Endoplasmic reticulum stress induces myostatin precursor protein and NF-κB in cultured human muscle fibers: Relevance to inclusion body myositis
Keywords: مهار پروتئازوم; Myostatin precursor protein; Myostatin; Endoplasmic reticulum stress; Inclusion body myositis; Nuclear factor-κB; Cultured human muscle fibers; Proteasome inhibition
Negative growth control of osteosarcoma cell by Bowman–Birk protease inhibitor from soybean; involvement of connexin 43
Keywords: مهار پروتئازوم; Bowman–Birk protease inhibitor; Cancer prevention; Connexin 43; Proteasome inhibition; Osteosarcoma cell
The proteasome inhibitor VELCADE® reduces infarction in rat models of focal cerebral ischemia
Keywords: مهار پروتئازوم; Embolic stroke; MCAO; Neuroprotection; Proteasome inhibition; Suture model;
Bortezomib (PS-341) in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer: A Southwest Oncology Group Phase II Trial (S0327)
Keywords: مهار پروتئازوم; Small cell lung cancer; Proteasome inhibition; Bortezomib; Bcl-2;
CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
Keywords: مهار پروتئازوم; Proteasome inhibition; Oxidative stress; 4-Hydroxynonenal; Alcoholic liver disease; Cytokeratin aggresome formation; Mallory bodies;
Bortezomib-Based Combinations in the Treatment of Non-Small-Cell Lung Cancer
Keywords: مهار پروتئازوم; Nuclear factor-κB; Proteasome inhibition; Sequential therapy; Thrombocytopenia;
Proteasome inhibition and Tau proteolysis: an unexpected regulation
Keywords: مهار پروتئازوم; AD; Alzheimer's disease; GSK3β; glycogen synthase kinase 3 beta; PARP; poly-(ADP-ribose)-polymerase; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; Tau protein; Proteolysis; Phosphorylation; Proteasome inhibition;