In vitro protein kinase activity measurement by flow cytometry
Keywords: پروتئین کیناز A; Akt; Protein kinase A; Protein kinase C; Flow cytometry; Kinase; Phosphorylation; Detection
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Phosphorylation of cysteine string protein on Serine 10 triggers 14-3-3 protein binding
Keywords: پروتئین کیناز A; Neurodegeneration; Exocytosis; Synapse; Chaperone; Protein kinase A; Akt
Dual regulation of renal Kir7.1 potassium channels by protein Kinase A and protein Kinase C
Keywords: پروتئین کیناز A; Electrophysiology; Potassium channel; Kir7.1; Signal transduction; Renal potassium secretion; Protein kinase A; Protein kinase C; Xenopus oocyte expression system
Effects of sulfonylurea drugs on adiponectin production from 3T3-L1 adipocytes: Implication of different mechanism from pioglitazone
Keywords: پروتئین کیناز A; SU, sulfonylurea; PKA, protein kinase A; PPAR, peroxisome proliferator-activated receptor; RT-PCR, reverse transcription-polymerase chain reactionAdiponectin; Sulfonylurea; Pioglitazone; Protein kinase A; Adipogenesis
The anti-apoptotic activity associated with phosphatidylinositol transfer protein α activates the MAPK and Akt/PKB pathway
Keywords: پروتئین کیناز A; PI-TP; phosphatidylinositol transfer protein; PI; phosphatidylinositol; PC; phosphatidylcholine; PLA; phospholipase A; MAPK; mitogen-activated protein kinase; ERK; extracellular signalling related kinase; IAP; inhibitor of apoptosis protein; PKB; protein
Chronic morphine treatment decreases the Cav1.3 subunit of the L-type calcium channel
Keywords: پروتئین کیناز A; Morphine; Opioid tolerance; Calcium channel; Protein kinase A; Dihydropyridin
Guanylyl cyclase and protein kinase G mediate nitric oxide suppression of 5-lipoxygenase metabolism in rat alveolar macrophages
Keywords: پروتئین کیناز A; AA; arachidonic acid; AK; protein kinase A; AM; alveolar macrophages; ANF; atrial naturetic factor; BSA; bovine serum albumin; EIA; enzyme-linked immunoassay; 5-LO; 5-lipoxygenase; FLAP; 5-lipoxygenase activating protein; GC; guanylyl cyclase; GK; protein
Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide
Keywords: پروتئین کیناز A; Carbon-11; PET; H-89; H-9; Protein kinase A; Signal transduction
Adrenomedullin enhances baroreceptor reflex response via cAMP/PKA signaling in nucleus tractus solitarii of rats
Keywords: پروتئین کیناز A; Adrenomedullin; Protein kinase A; Baroreceptor reflex; Nucleus tractus solitarii; Rat
Effect of GABAA receptor activation on UT-coupled signaling pathways in rat cortical astrocytes
Keywords: پروتئین کیناز A; AC; adenylyl cyclase; [Ca2+]c; cytosolic calcium concentration; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; GABAAR; gamma-aminobutyric acid type A receptor; GFAP; glial fibrillary acidic protein; GPCR; G protein-coupled receptor; HE
The role of loops 3 and 4 in the interdomains and intersubunits communication of E. coli cAMP receptor protein
Keywords: پروتئین کیناز A; PKA; protein kinase A; Epac; exchange protein directly activated by cAMP; CRP; cAMP receptor protein; CNGC; cyclic nucleotide-gated ion channels; CPM; N-{4-[7-(diethylamino)-4-methylcoumarin-3-yl]-phenyl}maieimide; WT; wild type; cAMP; 3â²,5â²-cyclic ad
Modeling and stochastic simulation of the Ras/cAMP/PKA pathway in the yeast Saccharomyces cerevisiae evidences a key regulatory function for intracellular guanine nucleotides pools
Keywords: پروتئین کیناز A; cAMP; Protein kinase A; Tau-leaping; Phosphodiesterase
Pentoxifylline impedes migration in B16F10 melanoma by modulating Rho GTPase activity and actin organisation
Keywords: پروتئین کیناز A; Pentoxifylline; B16F10 melanoma; Migration; Rho GTPase; Actin organisation; Protein Kinase A;
Ginsenosides Rg1 and Rb1 enhance glutamate release through activation of protein kinase A in rat cerebrocortical nerve terminals (synaptosomes)
Keywords: پروتئین کیناز A; Ginsenoside; Glutamate exocytosis; Voltage-dependent Ca2+ channel; Protein kinase A; Cerebrocortical synaptosomes
Low doses of cyclic AMP-phosphodiesterase inhibitors rapidly evoke opioid receptor-mediated thermal hyperalgesia in naïve mice which is converted to prominent analgesia by cotreatment with ultra-low-dose naltrexone
Keywords: پروتئین کیناز A; AC; adenylyl cyclase; β-FNA; β-funaltrexamine; cAMP; cyclic AMP; CTX-B; cholera toxin-B subunit; GM1; monosialoganglioside; IBMX; 3-isobutyl-1-methylxanthine; NLX; naloxone; NTX; naltrexone; nor-BNI; nor-binaltorphimine; PDE; phosphodiesterase; PKA; pro
βγ subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced
Keywords: پروتئین کیناز A; BDNF; brain-derived neurotrophic factor; CTX; cholera toxin; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EPAC; exchange protein activated by cAMP; ERK; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; G3
Endogenous hydrogen sulfide is involved in regulation of respiration in medullary slice of neonatal rats
Keywords: پروتئین کیناز A; respiratory regulation; medullary slices; discharge of hypoglossal rootlets; KATP channel; cAMP; AC; adenyl cyclase; ACSF; artificial cerebrospinal fluid; CBS; cystathionine β-synthase; CYS; cysteine; DF; discharge frequency; Gl; glibenclamide; IA; integ
A novel activating effect of the regulatory subunit of protein kinase A on catalytic subunit activity
Keywords: پروتئین کیناز A; Protein kinase A; Peptides; Linker domain I; Substrates; Regulatory subunit; Inhibition; Activation
Characterization of the transduction pathway involved in c-fos and c-jun expression induced by Aggregatibacter actinomycetemcomitans lipopolysaccharides in human gingival fibroblasts
Keywords: پروتئین کیناز A; Periodontal disease; Lipopolysaccharide; Inflammation; Phospholipase C; Protein kinase C; Protein kinase A; ERK 1/2; p38
The role of active zone protein Rab3 interacting molecule 1 alpha in the regulation of norepinephrine release, response to novelty, and sleep
Keywords: پروتئین کیناز A; amygdala; open field; REM; synaptic plasticity; Rim1αKO; ANOVA; analysis of variance; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene-glycol-bis(oxyethylenenitrilo)-tetraacetic acid; Hepes; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; KBH; K
Estrogen induces rapid translocation of estrogen receptor β, but not estrogen receptor α, to the neuronal plasma membrane
Keywords: پروتئین کیناز A; steroid; hormone; neuron; HT22; MAPK; subcellular localization; α; alpha; β; beta; CRE; cyclic AMP response element; DIV; days in vitro; ER; estrogen receptor; ERE; estrogen response element; ERK; extracellular signal related kinase; E18; gestational da
Hydrogen sulfide: Neurochemistry and neurobiology
Keywords: پروتئین کیناز A; AOAA; aminooxyacetate; ATP; adenosine triphosphate; camp; cyclic adenosine monophosphate; [Ca2+]i; intracellular calcium concentration; CBS; cystathionine-β-synthase; β-CNA; β-cyano-l-alanine; CSE; cystathionine-γ-lyase; Cys; l-cysteine; GABA; γ-amin
Overexpression of junctate induces cardiac hypertrophy and arrhythmia via altered calcium handling
Keywords: پروتئین کیناز A; Sarcoplasmic reticulum; Excitation–contraction coupling; Junctin; Transgenic mice; Protein kinase A; Compartmentalization
Oxidative stress and chronological aging in glycogen-phosphorylase-deleted yeast
Keywords: پروتئین کیناز A; SOD; superoxide dismutase; ROS; reactive oxygen species; PKA; protein kinase A; YPD; yeast extract peptone dextrose medium; SC; synthetic complete medium; wt; wild type; RT-PCR; reverse transcription-polymerase chain reaction; SEM; standard error of mea
Tissue-Specific Ablation of Prkar1a Causes Schwannomas by Suppressing Neurofibromatosis Protein Production
Keywords: پروتئین کیناز A; CNC; Carney complex; GAP; GTPase-activating protein; KO; knock (ed) out; NF; neurofibromatosis; PKA; protein kinase A; PNST; peripheral nerve sheath tumor; TEC; tyrosinase-enhanced Cre; TEC3KO; TEC3;Prkar1aloxP/loxP;
Functional characterization of the Aspergillus fumigatusPHO80 homologue
Keywords: پروتئین کیناز A; Aspergillus fumigatus; Inorganic phosphate acquisition; PHO80; Protein kinase A
Cadherin-11 interacts with the FGF receptor and induces neurite outgrowth through associated downstream signalling
Keywords: پروتئین کیناز A; Cad11-Fc or Ncad-Fc; cadherin-11 or N-cadherin extracellular domain fused to the human-Fc fragment of immunoglobulin; N-CAM; Neural Cell Adhesion Molecule; CAM kinase; Calmoduline kinase; DAG lipase; Diacyl glycerol lipase; ERK1/2; extracellular signa
Dexamethasone and GLP-2 administered to rat dams during pregnancy and lactation have late effects on intestinal sugar transport in their postweanling offspring
Keywords: پروتئین کیناز A; Akt/PKB; Protein kinase B; BBM; brush border membrane; BLM; basolateral membrane; DEX; dexamethasone; EGF; epidermal growth factor; GC; glucocorticosteroids; GLP-2; glucagon-like peptide-2; GLUT; glucose transporter; GSK-3; glycogen synthase kinase 3; IGF
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice
Keywords: پروتئین کیناز A; PACAP; Hedgehog; Medulloblastoma; Pathched; Cerebellum; Protein kinase A; Pituitary adenylyl cyclase activating peptide; PKA; cAMP; Brain tumor
Characterization of the hypothalamic proopiomelanocortin gene and β-endorphin expression in the hypothalamic arcuate nucleus of mice elicited by inflammatory pain
Keywords: پروتئین کیناز A; proopiomelanocortin; beta-endorphin; inflammatory pain; hypothalamus; ACTH; adrenocorticotropin; BSA; bovine serum albumin; CaMK-IIα; calmodulin kinase IIα; CRH; corticotropin-releasing hormone; DIG; digoxigenin; i.t.; intrathecal; MAPK; mitogen-activat
Glutamate-mediated spinal reflex potentiation involves ERK 1/2 phosphorylation in anesthetized rats
Keywords: پروتئین کیناز A; Extracellular signal-regulated kinase; Phosphorylation; Protein kinase A; Protein kinase C; GlutamateAMPA, α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionate; BIS7, bisindolylmaleimide VII; CNQX, 6-cyano-7-nitroquinoxaline-2,4-dione; DIS, bladder saline di
Adenosine 3â²,5â²-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors
Keywords: پروتئین کیناز A; Complex I; cAMP; Protein kinase A; NRTI; Superoxide;
cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression
Keywords: پروتئین کیناز A; cAMP signaling; Histone phosphorylation; Cell cycle; Protein kinase A; Cyclin-dependent kinase; Cyclin B
Serotonin delays habituation of leech swim response to touch
Keywords: پروتئین کیناز A; Central pattern generation; Interneurons; Adenylyl cyclase; Protein kinase A
Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk
Keywords: پروتئین کیناز A; Pfmrk; CDK7; Protein kinase A; Malaria; Plasmodium falciparum; Kinase inhibitors; Cyclin dependent protein kinase; Anti-malarials; Drug target; Parasite
A genome-wide assessment of adrenocorticotropin action in the Y1 mouse adrenal tumor cell line
Keywords: پروتئین کیناز A; ACTH; Alternative splicing; cAMP; cDNA microarray; Protein kinase A; Protein kinase C; Y1 mouse adrenocortical tumor cells
Functional interaction between dopamine receptor subtypes for the regulation of c-fos expression
Keywords: پروتئین کیناز A; Dopamine receptor; c-fos; Ral; RGL; Protein kinase A;
DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation
Keywords: پروتئین کیناز A; Cardiomyopathy; Contractility; Calcium regulation; Mutation; Thin filament; Phosphorylation; Troponin; Protein kinase A; Protein kinase C;
A rapid inhibition of NMDA receptor current by corticosterone in cultured hippocampal neurons
Keywords: پروتئین کیناز A; Acute effect; Corticosterone; Protein kinase A; NMDA receptor; hippocampus; Whole-cell patch clamp
Co-localization of p-CREB and p-NR1 in spinothalamic neurons in a chronic muscle pain model
Keywords: پروتئین کیناز A; cAMP pathway; Protein kinase A; Phosphorylation; Nociception
Endothelin-1 reduces mesenteric microvascular hydraulic permeability via cyclic AMP and protein kinase A signal transduction
Keywords: پروتئین کیناز A; Endothelin-1; cAMP; cGMP; Protein kinase A; Microvascular permeability; Hydraulic permeability;
Protein kinase C-dependent antilipolysis by insulin in rat adipocytes
Keywords: پروتئین کیناز A; β-AR; β-adrenergic receptor; α-AR; α-adrenergic receptor; PKA; protein kinase A; PKC; protein kinase C; PKB; protein kinase B; PDK; phosphoinositide-dependent protein kinase; PI3K; phosphatidylinositol 3-kinase; PIP3; phosphatidylinositol 3,4,5-tripho
Trypanosoma cruzi epimastigotes: Regulation of myo-inositol transport by effectors of protein kinases A and C
Keywords: پروتئین کیناز A; Chagas’ disease; myo-Inositol transport; cAMP; Protein kinase A; Protein kinase C; Trypanosoma cruzi; Inositol; PBS, phosphate-buffered saline; dBcAMP, dibutyryl cyclic-adenosine monophosphate; IBMX, isobutyl-methyl-xanthine; PMA, phorbol-12-myristate-13-
Severity of alcohol-induced painful peripheral neuropathy in female rats: Role of estrogen and protein kinase (A and Cε)
Keywords: پروتئین کیناز A; ethanol; hyperalgesia; estrogen; second messenger signaling; CD; control diet; DMSO; dimethyl sulfoxide; ED; ethanol (6.5%, v:v) diet; ERK; extracellular-signal related kinase; IF; gonad-intact female; IM; gonad-intact male; MEK; mitogen and extracellular
Pain signalling pathways: From cytokines to ion channels
Keywords: پروتئین کیناز A; NGF; nerve growth factor; TNFα; tumor necrosis factor α; IL-Iβ; interleukin 1β; PLCβ; phospholipase Cβ; PLA2; phospholipase A2; PKC; protein kinase C; TTX-R; tetrodotoxin-resistant; AA; arachidonic acid; PGE2; prostaglandin E2; COX; cyclooxygenase;
Novel mechanism of cyclic AMP mediated extracellular signal regulated kinase activation in an intestinal cell line
Keywords: پروتئین کیناز A; cAMP; ERK1/2; Protein kinase A; Cell survival; Apoptosis;
Effects of tau phosphorylation on proteasome activity
Keywords: پروتئین کیناز A; AD; Alzheimer's disease; NFT; neurofibrillary tangle; HEK293; human embryonic kidney cell; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide thiazolyl blue; BCA; bicinchoninic acid; PKA; protein kinase A; PP1; protein phosphotase 1; PP2A
The role of ghrelin and some intracellular mechanisms in controlling the secretory activity of chicken ovarian cells
Keywords: پروتئین کیناز A; Ghrelin; Progesterone; Testosterone; Estradiol; Arginine–vasotocin; Protein kinase A; MAP kinase (ERK1, 2); CDC2 kinase (p34)
H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A
Keywords: پروتئین کیناز A; 3T3-L1 cells; Adipogenesis; H-89; Protein kinase A; Rho kinase; Phosphoinositide 3-kinase; Akt; Ras; Extracellular signal-regulated kinase 1/2
Cyclic AMP-dependent modulation of cardiac L-type Ca2+ and transient outward K+ channel activities by epoxyeicosatrienoic acids
Keywords: پروتئین کیناز A; Cytochrome P450; Arachidonic acid; Epoxyeicosatrienoic acid; Ion channel; cAMP; Protein kinase A