دانلود مقالات ISI درباره PTM، اصلاح post-translational + ترجمه فارسی

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Prediction of sumoylation sites in proteins using linear discriminant analysis

Keywords: PTM، اصلاح post-translational; PTM, post-translational modification; LDA, linear discriminant analysis; PSSM, position specific scoring matrix; PSPM, position-specific propensity matrices; CKSAAP, the composition of k-space amino acid pair; F-score, feature scoreF-score; Post-translati

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Structural basis of the lack of endo-glucanase inhibitory activity of Lupinus albus γ-conglutin

Keywords: PTM، اصلاح post-translational; Seed proteins; Enzyme inhibitors; Mutagenesis; Plant defenceDLS, dynamic light scattering; GH, glycosyl hydrolase; PTM, post-translational modification; s.i., sequence identity; γ-c, seed-extracted γ-conglutin; rγc, recombinant γ-conglutin; rγcMu, recombi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Lysine acetylation stabilizes SP2 protein in the silkworm Bombyx mori

Keywords: PTM، اصلاح post-translational; TSA, Trichostatin A; MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; PTM, post-translational modification; p300, histone acetyltransferases p300; CREB, cAMP-response element binding protein; CBP, CREB binding protein; PCAF, p300/CB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of post-translational modifications in full-length human BMP-1 confirms the presence of a rare vicinal disulfide linkage in the catalytic domain and highlights novel features of the EGF domain

Keywords: PTM، اصلاح post-translational; AEBSF, 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride; BMP-1, bone morphogenetic protein 1; DTT, dithiothreitol; NEM, N-ethylmaleimide; PTM, post-translational modification; LC, liquid chromatography; ETD, electron transfer dissociation; CID, col

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The Nutrient-Dependent O-GlcNAc Modification Controls the Expression of Liver Fatty Acid Synthase

Keywords: PTM، اصلاح post-translational; HCD, high-carbohydrate diet; FAS, fatty acid synthase; HBP, hexosamine biosynthesis pathway; PTM, post-translational modification; OGT, O-GlcNAc transferase; OGA, O-GlcNAcase; ChREBP, carbohydrate responsive element-binding protein; LXR, liver X receptor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

A SUMO-acetyl switch in PXR biology

Keywords: PTM، اصلاح post-translational; PXR, pregnane X receptor; TSA, trichostatin A; HDAC3, histone de-acetylase 3; SMRT, silencing mediator of retinoic acid and thyroid hormone receptor; PTM, post-translational modification; LC–MS/MS, liquid chromatography–tandem mass spectrometry; PIAS1, pr

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity

Keywords: PTM، اصلاح post-translational; LC–MS/MS, liquid chromatography coupled to mass spectrometry; PTM, post-translational modification; DR, direct repeats; ER, everted repeats; NR, nuclear receptor; IP, immunoprecipitation; FLAG, FLAG octapeptide; Ac-CoA, acetyl coenzyme A; AcK, acetyllysin

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Histone H3 Ser57 and Thr58 phosphorylation in the brain of 5XFAD mice

Keywords: PTM، اصلاح post-translational; Aβ, amyloid-β; APP, amyloid precursor protein; MRM, multiple reaction monitoring; PTM, post-translational modification; S57, serine-57; T58, threonine-58Phosphorylation; Histone; 5XFAD; Alzheimer’s disease; Multiple reaction monitoring

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

HSFs, Stress Sensors and Sculptors of Transcription Compartments and Epigenetic Landscapes

Keywords: PTM، اصلاح post-translational; HSF, heat shock factor; TF, transcription factor; HS, heat shock; HSE, heat shock element; HSP, heat shock protein; HSR, heat shock response; DBD, DNA-binding domain; PTM, post-translational modification; HAT, histone acetyltransferase; HDAC, histone deac

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

Methylation of yeast ribosomal protein S2 is elevated during stationary phase growth conditions

Keywords: PTM، اصلاح post-translational; PTM, post-translational modification; RPS1B, ribosomal protein S1B; RPS2, ribosomal protein S2; BCA, bicinchoninic acid; HPLC, high-performance liquid chromatography; ESI, electrospray ionization; m/z, mass-to-charge ratio; HCD, higher-energy collisional

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Neuronal process structure and growth proteins are targets of heavy PTM regulation during brain development

Keywords: PTM، اصلاح post-translational; HMP, Heavily modified protein; MARCKS, Myristolated alanine-rich c-kinase substrate; MAP, Microtubule-associated protein; NCAM, Neural cell adhesion molecule; NFH, Neurofilament heavy polypeptide; NP, Neuronal process; PTM, Post-translational modification

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Extended bottom-up proteomics with secreted aspartic protease Sap9

Keywords: PTM، اصلاح post-translational; AGC, automatic gain control; ETD, electron transfer dissociation; FTMS, Fourier transform mass spectrometer/mass spectrometry; HCD, higher energy collision dissociation; IAA, iodoacetamide; MeOH, methanol; PTM, post-translational modification; RFU, relati

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative evaluation of two cell-free protein synthesis systems derived from Escherichia coli for genetic code reprogramming

Keywords: PTM، اصلاح post-translational; CFPS, cell-free protein synthesis; NAA, non-proteinogenic amino acid; PTM, post-translational modification; acK, acetyllysine; meK, methyllysine; 4-nt codon, 4 nucleotide codonGenetic code reprogramming; Cell-free protein synthesis; Flexizyme; Methyllysin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Role of antisense RNAs in evolution of yeast regulatory complexity

Keywords: PTM، اصلاح post-translational; RNAi, RNA interference; PTM, post-translational modification; TFBS, transcription factor binding site; PPI, protein–protein interactions; IDR, intrinsically disordered region; SAL/SRL, the ratio of sense–antisense overlapping length to sense transcript le

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Analysis of human serum phosphopeptidome by a focused database searching strategy

Keywords: PTM، اصلاح post-translational; PTM, post-translational modification; CID, collision-induced dissociation; ETD, electron-transfer dissociation; MSA, multi-stage activation; FDR, false discovery rate; HuSPep, human serum pro-peptidome target/decoy database; PPD, Plasma Proteome Database;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Ubiquitin: Molecular modeling and simulations

Keywords: PTM، اصلاح post-translational; Computer simulations; Molecular dynamics; Molecular modeling; UbiquitinAFM, atomic force microscopy; DUB, deubiquitinating enzyme; MD, molecular dynamics; PTM, post-translational modification; RDC, residual dipolar coupling; Ub, ubiquitin; UBC, Ub-conjuga

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenomic regulation of bile acid metabolism: Emerging role of transcriptional cofactors

Keywords: PTM، اصلاح post-translational; FXR, farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptor; DBD, DNA binding domain; LBD, ligand binding domain; GPCR, G-protein coupled receptor; GLP-1, glucagon-like peptide 1; ChIP, chromatin immunoprecipitation; Cyp7a1, chol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Tyrosine phosphorylation plays a role in increasing maspin protein levels and its cytoplasmic accumulation

Keywords: PTM، اصلاح post-translational; DTT, dithiothreitol; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IEF, isoelectric focalization; PTM, post-translational modification; serpin, serine protease inhibitor; 2D-SDS-PAGE, two-dimensional sodium dodecyl sulfate polyacrylamide gel electropho

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Substrate targeting by the ubiquitin–proteasome system in mitosis

Keywords: PTM، اصلاح post-translational; APC/C, Anaphase-Promoting Complex/Cyclosome; CDK, cyclin-dependent kinase; CP, core particle (20S proteasome); D-box, destruction box (degron); DUB, deubiquitinase; KEN box, K-E-N motif (degron); PTM, post-translational modification; RP, regulatory partic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate

Keywords: PTM، اصلاح post-translational; DUB, deubiquitylase; MS, mass spectrometry; PTM, post-translational modification; ATP, adenosine triphosphate; K48, the forty-eighth amino acid of ubiquitin, a lysine; K63, the sixty-third amino acid of ubiquitin, a lysine; TUBEs, tandem ubiquitin binding

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Assessing ubiquitination of viral proteins: Lessons from flavivirus NS5

Keywords: PTM، اصلاح post-translational; AP, affinity purification; R, arginine; DUB, deubiquitinase; FFU, focus forming units; LGTV, Langat virus; IP, immunoprecipitation; IFN, interferon; K, lysine; NEM, N-ethylmaleimide; NS5, nonstructural protein 5; PTM, post-translational modification; RIPA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications

Keywords: PTM، اصلاح post-translational; FXR, Farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptors; AF-1, activation function 1; AF-2, activation function 2; DBD, DNA binding domain; LBD, ligand binding domain; CDCA, chenodeoxycholic acid; FXRE, FXR response element;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Osteoclast migration on phosphorylated osteopontin is regulated by endogenous tartrate-resistant acid phosphatase

Keywords: PTM، اصلاح post-translational; OPN, osteopontin; bmOPN, bovine milk osteopontin; hrOPN, human recombinant osteopontin; hmOPN, human milk osteopontin; PTM, post-translational modification; TRAP, tartrate-resistant acid phosphatase; RGD, Arg-Gly-Asp; pNPP, p-nitrophenyl phosphate, 4-nitr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Proteomics application of crops in the context of climatic changes

Keywords: PTM، اصلاح post-translational; ABA, abscisic acid; ADH, alcohol dehydrogenase; APX, ascorbate peroxidase; GSH, glutathione; GST, glutathione S-transferase; HSP, heat shock protein; MudPIT, multidimensional protein identification technology; PTM, post-translational modification; PR, pat

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

The α-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC

Keywords: PTM، اصلاح post-translational; eEF-2, eukaryotic elongation factor-2; LC-MS/MS, nanoliquid chromatography–tandem mass spectrometry; PTM, post-translational modification; WT, wild-typeα-Kinase; TRPM6; TRPM7; Myosin II; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

TTLL10 is a protein polyglycylase that can modify nucleosome assembly protein 1

Keywords: PTM، اصلاح post-translational; PTM, post-translational modification; NAP, nucleosome assembly protein; TTLL, tubulin tyrosine ligase-like; R-polygly, anti-poly-glycine polyclonal antibody; mAb, monoclonal antibody; cDNA, complementary DNA; PCR, polymerase chain reactionGlycylation; Gly

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Modulation of lysine acetylation-stimulated repressive activity by Erk2-mediated phosphorylation of RIP140 in adipocyte differentiation

Keywords: PTM، اصلاح post-translational; ERK1/2, extracellular-signal-related kinase 1/2; HAT, histone acetyltransferase; HDAC, histone deacetylase; MAPK, mitogen-activated protein kinase; MS, mass spectrometry; PLP, pyridoxal 5′-phosphate; PTM, post-translational modification; RIP140, receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Cardiovascular Proteomics: Tools to Develop Novel Biomarkers and Potential Applications

Keywords: PTM، اصلاح post-translational; ELISA, enzyme-linked immunoadsorbent assay; HUPO, Human Proteomic Organisation; PTM, post-translational modification

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه