دانلود مقالات ISI درباره PTX، سموم سوراخ دار + ترجمه فارسی

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Systemic ocular antigen immunization leads only to a minor secondary immune response

Keywords: PTX، سموم سوراخ دار; ONA, Optic nerve homogenate antigen; Co, Control; RGCs, Retinal ganglion cells; FA, Freund's Adjuvants; PTx, Pertussis toxin; IgG, Immunoglobulin G; CNS, Central nervous system; cLN, Cervical lymph nodesGlaucoma; Retina degeneration; Lymphocytes; Granuloc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of microglial P2Y12 receptor is required for outward potassium currents in response to neuronal injury

Keywords: PTX، سموم سوراخ دار; 4-AP, 4-aminopyridine; ACSF, artificial cerebrospinal fluid; CNS, central nervous system; P2Y12 KO, P2Y12R knockout; P2Y12R, P2Y12 receptors; PI3K, phosphoinositide 3-kinase; PTX, pertussis toxin; TEA, tetraethylammoniummicroglia; P2Y12 receptor; ATP; K+

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

In vitro comparison of duration of action of melatonin agonists on melatonin MT1 receptor: Possible link between duration of action and dissociation rate from receptor

Keywords: PTX، سموم سوراخ دار; CHO, Chinese hamster ovary; CHO-hMT1, CHO cells stably expressing human melatonin MT1 receptor; FBS, fetal bovine serum; mHBSS, modified Hanks׳ balanced salt solution; PTX, pertussis toxin; PBS, phosphate-buffered saline; SCN, suprachiasmatic nucleus2-Iod

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Forskolin-free cAMP assay for Gi-coupled receptors

Keywords: PTX، سموم سوراخ دار; AC, adenylate cyclase; AUC, area under the curve; cAMP, cyclic adenosine monophosphate; ERK, extracellular signal regulated kinases; FSK, forskolin; GPCRs, G-protein coupled receptors; PTX, pertussis toxin; SA, succinic acidGPCR; SUCNR1; cAMP; Forskolin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE

Keywords: PTX، سموم سوراخ دار; Mast cells; Neutrophils; EAE; MS; Meningeal inflammationCFA, complete Freund's adjuvant; PTX, pertussis toxin; DC, dendritic cell; BMMC, bone marrow mast cells; BBB, blood brain barrier; CSF, cerebral spinal fluid; CNS, central nervous system; MS, multipl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of TRPC4β by Gαi subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron

Keywords: PTX، سموم سوراخ دار; TRPC, transient receptor potential canonical; GPCR, G-protein-coupled receptor; EGFP, enhanced GFP; GTPγS, guanosine5′-3-O-(thio)triphosphate; PTX, pertussis toxin; PIP2, phosphatidylinositol 4,5-bisphosphate; CaMK, Ca2+/calmodulin-dependent protein kinas

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

N-arachidonoyl glycine induces macrophage apoptosis via GPR18

Keywords: PTX، سموم سوراخ دار; NAGly, N-arachidonoyl glycine; AEA, N-arachidonoyl ethanol amide; CCK-8, cell counting kit-8; PTX, pertussis toxin; M1, classically activated macrophages; M2, alternatively activated macrophages; MEK, MAPK/ERK kinaseN-arachidonoyl glycine; Macrophage; Apo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Chronic treatment with the opioid antagonist naltrexone favours the coupling of spinal cord μ-opioid receptors to Gαz protein subunits

Keywords: PTX، سموم سوراخ دار; Opioid antagonist; Opioid receptors; G-protein; Adenylyl cyclase; Constitutive activity; Inverse agonismAC, Adenylyl cyclase; DAMGO, Tyr-d-Ala-Gly-Me-Fe-Gly-ol-enkephalin; FK, Forskolin; ODN, oligodeoxyribonucleotides; PTX, Pertussis toxin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibitors of diacylglycerol metabolism reduce time to the onset of glutamate release potentation by mGlu7 receptors

Keywords: PTX، سموم سوراخ دار; BSA, bovine serum albumin; [Ca2+]c, cytosolic free Ca concentration; HBM, HEPES buffer medium; DAG, diacylglycerol; PLC, phospholipase C; PTx, pertussis toxin; mGlu7 receptor, metabotropic glutamate receptor 7; PKA, cAMP-dependent protein kinase; PKC, pro

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin

Keywords: PTX، سموم سوراخ دار; PTX, Pertussis toxin; GrB, Granzyme B; APC, antigen presenting cellPertussis toxin; T cell expansion; Cytokines; Costimulatory molecules

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Heterotrimeric Gαi proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis

Keywords: PTX، سموم سوراخ دار; ANOVA, analysis of variance; CLP, cecal ligation and puncture; FCS, fetal calf serum; GPCR, G protein coupled receptors; IL, interleukin; LPS, lipopolysaccharide; MP-7, Mastoparan; MPO, myeloperoxidase; PTx, pertussis toxin; TLR, Toll-like receptor; TNF,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

A method of generating antibodies against exogenously administered self-antigen by manipulating CD4+CD25+ regulatory T cells

Keywords: PTX، سموم سوراخ دار; Treg, regulatory T cells; mAb, monoclonal antibody; PE, phycoerythrin; FITC, fluorescein-isothiocyanate; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; PTX, pertussis toxin; ELISA, enzyme-linked immunosorbent assay; HRP, horseradish

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells

Keywords: PTX، سموم سوراخ دار; ROS, reactive oxygen species; FPRL1, formyl peptide receptor-like 1; ERK, extracellular-signal-regulated kinase; PTX, pertussis toxin; EGFR, epidermal growth factor receptor; STAT, signal transducer and activator of transcriptionNADPH oxidase; Reactive ox

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Activation of human monocytes by a formyl peptide receptor 2-derived pepducin

Keywords: PTX، سموم سوراخ دار; FPR2, formyl peptide receptor 2; SAA, serum amyloid A; GPCR, G-protein coupled receptor; PTX, pertussis toxin; MAPKs, mitogen activated protein kinases; [Ca2+]i, intracellular calcium concentration; HPF, high-power fields; WRW4, WRWWWW; PLC, phospholipase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori

Keywords: PTX، سموم سوراخ دار; GPCR, G protein-coupled receptor; AKH, adipokinetic hormone; Hez-HrTH, Heliothis zea hypertrehalosaemic hormone; MAPK, mitogen-activated protein kinase; ERK1/2, extracellular signal-regulated kinase1/2; PTX, pertussis toxin; CTX, cholera toxinAdipokinetic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Distinct modes of molecular regulation of CCL3 induced calcium flux in monocytic cells

Keywords: PTX، سموم سوراخ دار; CHO cells, Chinese hamster ovary cells; FCS, foetal calf serum; FITC, fluorescein isothiocyanate; HEK, human embryonic kidney; InsP3, inositol 1,4,5-trisphosphate receptor; MCD, methyl-β-cyclodextrin; PBS, phosphate buffered saline; PTX, pertussis toxin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Ultra-low dose naloxone restores the antinociceptive effect of morphine in pertussis toxin-treated rats by reversing the coupling of μ-opioid receptors from Gs-protein to coupling to Gi-protein

Keywords: PTX، سموم سوراخ دار; intrathecal injection; G-protein; ADP-ribosylate; immunoprecipitation; neuropathic pain; opioidEGFR, epidermal growth factor receptor; G-protein, guanine nucleotide-binding protein; PBS, phosphate-buffered saline; PTX, pertussis toxin; RT-PCR, reverse tra

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Sphingosine 1-phosphate induces Mcl-1 upregulation and protects multiple myeloma cells against apoptosis

Keywords: PTX، سموم سوراخ دار; S1P, sphingosine-1-phosphate; MM, multiple myeloma; S1PR, S1P receptor; PTX, pertussis toxin; MAPK, mitogen-activated protein kinase; PI3K, Phosphoinositide-3 kinase; SPK, sphingosine kinaseMultiple myeloma; Sphingosine1-phosphate; Mcl-1; Apoptosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Cyclic phosphatidic acid — A unique bioactive phospholipid

Keywords: PTX، سموم سوراخ دار; CPA, cyclic phosphatidic acid; GPCR, G-protein coupled receptors; LPA, lysophosphatidic acid; CCPA, carba-CPA; PLD, phospholipase D; LPC, lysophosphatidyl choline; ATX, autotaxin; PTX, pertussis toxin; cAMP, cyclic AMP; EDG, endothelial differentiation ge

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

F2L, a peptide derived from heme-binding protein, inhibits LL-37-induced cell proliferation and tube formation in human umbilical vein endothelial cells

Keywords: PTX، سموم سوراخ دار; FPR, formyl peptide receptor; FPRL, FPR-like; PTX, pertussis toxin; WKYMVm, Trp-Lys-Tyr-Met-Val-D-Met; F2L, Ac-MLGMIKNSLFGSVETWPWQVL; HUVECs, human umbilical vein endothelial cells; EBM, endothelial basal medium; WRW4, WRWWWW; FBS, fetal bovine serum; S1P

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

CCR5 internalisation and signalling have different dependence on membrane lipid raft integrity

Keywords: PTX، سموم سوراخ دار; CHO cells, Chinese hamster ovary cells; FCS, foetal calf serum; FITC, fluorescein isothiocyanate; HEK, human embryonic kidney; MCD, methyl-β-cyclodextrin; PBS, phosphate buffered saline; PTX, Pertussis toxin; TRITC, tetramethyl rhodamine isothiocyanateChe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Requirement of Gαi in thymic homing and early T cell development

Keywords: PTX، سموم سوراخ دار; CMJ, corticomeduallary junction; DN cells, CD4−CD8− cells; DP, CD4+CD8+ cells; Gαi, G protein inhibitory subunit α; KO, knockout; lin− cells, lineage-negative cells; mAb, monoclonal antibody; PTX, pertussis toxin; SP cells, CD4+ or CD8+ cells; WT, wild ty

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis

Keywords: PTX، سموم سوراخ دار; GH, growth hormone; GHS-R, growth hormone secretagogue-receptor; mRNA, messenger ribonucleic acid; PTX, pertussis toxin; [Ca2+]i, cytosolic Ca2+ concentration; ACh, acetylcholine; KATP channel, ATP-sensitive K+ channel; Kv channel, delayed rectifier K+ ch

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

PKC-δ/c-Src-mediated EGF receptor transactivation regulates thrombin-induced COX-2 expression and PGE2 production in rat vascular smooth muscle cells

Keywords: PTX، سموم سوراخ دار; PAR, proteinase-activated receptor; GPCR, G protein-coupled receptor; PTX, pertussis toxin; COX-2, cyclooxygeanse-2; PGE2, prostaglandin E2; PKC, protein kinase C; VSMC, vascular smooth muscle cell; EGFR, epidermal growth factor receptor; MAPK, mitogen ac

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia

Keywords: PTX، سموم سوراخ دار; ATX, autotaxin; LPA, lysophosphatidic acid; PLC-γ1, phospholipase C-γ1; PTX, pertussis toxin; VIL/FL, full-length human villin; VIL/AYFM, tyrosine phosphorylation site mutant of human villin; DOX, doxycycline; S1P1, sphingosine 1 phosphate 1; SEYFP, super

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Lysophosphatidylethanolamine stimulates chemotactic migration and cellular invasion in SK-OV3 human ovarian cancer cells: Involvement of pertussis toxin-sensitive G-protein coupled receptor

Keywords: PTX، سموم سوراخ دار; LPA, lysophosphatidic acid; LPS, lysophosphatidylserine; LPG, lysophosphatidylglycerol; GPCR, G-protein coupled receptor; LPE, lysophosphatidylethanolamine; fura-2/AM, fura-2 pentaacetoxymethylester; PTX, pertussis toxin; ERK, extracellular signal regulat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Expression and functional role of formyl peptide receptor in human bone marrow-derived mesenchymal stem cells

Keywords: PTX، سموم سوراخ دار; MSCs, mesenchymal stem cells; FPR, formyl peptide receptor; fMLF, N-formyl-met-leu-phe; CsH, cyclosporine H; PTX, pertussis toxin; LY294002, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; Fura-2/AM, fura-2 pentaacetoxymethylester; BAPTA/AM, 1,2-bis(o-a

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Novel neurotrophic effects of sphingosylphosphorylcholine in cerebellar granule neurons and in PC12 cells

Keywords: PTX، سموم سوراخ دار; CGNs, cerebellar granule neurons; HK, high potassium; FCS, fetal calf serum; GPCR, G protein-coupled receptor; LK, low potassium; LPA, lysophosphatidic acid; LPC, lysophosphatidylcholine; NGF, nerve growth factor; PTX, pertussis toxin; S-1-P, sphingosine-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of lysophosphatidylglycerol on several signaling molecules in OVCAR-3 human ovarian cancer cells: Involvement of pertussis toxin-sensitive G-protein coupled receptor

Keywords: PTX، سموم سوراخ دار; LPA, lysophosphatidic acid; GPCR, G-protein coupled receptor; LPG, lysophosphatidylglycerol; fura-2/AM, fura-2 pentaacetoxymethylester; PTX, pertussis toxin; ERK, extracellular signal regulated protein kinase; [Ca2+]i, intracellular calcium concentration;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

More than chemotaxis: A new anti-tumor DC vaccine modified by rAAV2-SLC

Keywords: PTX، سموم سوراخ دار; SLC, secondary lymphoid tissue chemokine; HCC, hepatocellular carcinoma; BMDC, bone marrow derived dendritic cell; rAAV2, adeno-associated virus serotype 2; PTX, pertussis toxin; HEV, high endothelial venules; p.i., postinfection; PI, proliferation index;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line

Keywords: PTX، سموم سوراخ دار; SCFAs, short-chain fatty acids; PTX, pertussis toxin; MAPK, mitogen-activated protein kinase; HSP27, heat shock protein 27; PMNC, polymorphonuclear cells; GPCR, G protein coupled receptors; PI3K, phosphatidylinositol 3-kinase; JNK, c-jun N-terminal kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Antiproliferative effect of sphingosylphosphorylcholine in thyroid FRO cancer cells mediated by cell cycle arrest in the G2/M phase

Keywords: PTX، سموم سوراخ دار; SPC, sphingosylphosphorylcholine; S1P, sphingosine-1-phosphate; Ptx, pertussis toxin; PLC, phospholipase C; PKC, protein kinase C; PKB, protein kinase B; MAPK, mitogen-activated protein kinase; FBS, foetal bovine serum; MTT, 3-(4,5 dimethylthiazol-2yl) 2-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Molecular aspects of the histamine H3 receptor

Keywords: PTX، سموم سوراخ دار; H3R, histamine H3 receptor; hH3R, human histamine H3 receptor; PLA2, phospholipase A2; TM, transmembrane domain; GPCR, G-protein coupled receptor; NHE, Na+/H+-exchanger; PI3K, phospho-inositol-3-kinase; PTX, pertussis toxin; PKA, protein kinase KHistamine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Chronic morphine treatment up-regulates mu opioid receptor binding in cells lacking filamin A

Keywords: PTX، سموم سوراخ دار; GPCR, G-protein-coupled receptor; PTX, pertussis toxin; MOP, mu opioid receptor; DAMGO, [d-Ala2,N-MePhe4-Gly-ol5]enkephalinMu opioid receptor; Up-regulation; Filamin A; Melanoma cells; Morphine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Arthropod D2 receptors positively couple with cAMP through the Gi/o protein family

Keywords: PTX، سموم سوراخ دار; CPG, central pattern generator; GPCR, G protein coupled receptor; DA, dopamine; DAR, dopamine receptor; PKA, protein kinase A; PP2A, protein phosphatase 2A; PTX, pertussis toxin; Et-18-OCH3, 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphorylcholine; IBMX,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Sphingosylphosphorylcholine enhances calcium entry in thyroid FRO cells by a mechanism dependent on protein kinase C

Keywords: PTX، سموم سوراخ دار; SPC, sphingosylphosphorylcholine; S1P, sphingosine-1-phosphate; PTX, pertussis toxin; PKC, protein kinase C; PMA, phorbol 12-myristate-13-acetate; DAG, diacylglycerol; OAG, 1-oleoyl-2-acetyl-sn-glycerol; [Ca2+]i, intracellular free calcium concentration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Lysophospholipids elevate [Ca2+]i and trigger exocytosis in bovine chromaffin cells

Keywords: PTX، سموم سوراخ دار; Lysophospholipid; Intracellular Ca2+ stores; Exocytosis; Ca2+ current; CapacitanceCICR, calcium-induced calcium release; LPA, lysophosphatidic acid; LPL, lysophospholipid; PLC, phospholipase C; Ptx, pertussis toxin; S1P, sphingosine 1-phosphate; Tg, thaps

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Activation of muscarinic M4 receptor augments NGF-induced pro-survival Akt signaling in PC12 cells

Keywords: PTX، سموم سوراخ دار; mAChR, muscarinic acetylcholine receptor; GPCR, G protein-coupled receptor; NGF, nerve growth factor; RTK, receptor tyrosine kinase; CCh, carbachol; PTX, pertussis toxin; PI3K, phosphatidylinositol 3-kinase; PDGF, platelet-derived growth factor; EGF, epid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Involvement of G-protein βγ subunits on the influence of inhibitory α2-autoreceptors on the angiotensin AT1-receptor modulation of noradrenaline release in the rat vas deferens

Keywords: PTX، سموم سوراخ دار; AC, adenylyl cyclase; Rp-cAMPS, Rp-adenosine-3′,5′-cyclic-monophosphorothioate triethylammonium; 9-CP-Ade, 9-(cyclopentyl)-adenine; DPCPX, 8-cyclopentyl-1,3-dipropylxanthine; PTX, pertussis toxin; PMA, phorbol 12-myristate 13-acetate; 4-M-PMA, phorbol-12-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Different receptors mediate the electrophysiological and growth cone responses of an identified neuron to applied dopamine

Keywords: PTX، سموم سوراخ دار; G-protein; cell culture; dopamine receptors; neurite outgrowth; Lymnaea stagnalisCM, conditioned medium; CTX, cholera toxin; GDP-β-S, guanosine 5′-o-(2-thiobiphosphate); PeA, pedal A; PTX, pertussis toxin; RMP, resting membrane potential; RPA, right parie

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes

Keywords: PTX، سموم سوراخ دار; 2-AG, 2-arachidonoylglycerol; DMSO, dimethyl sulfoxide; FBS, fetal bovine serum; HBSS, Hanks’ balanced salt solution; mAb, monoclonal antibody; MAP kinase, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; PTX, pertussis toxin; TPA, 1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه