Keywords: PZQ; Liver echotexture; Portal vein; Splenic vein; ANOVA; analysis of variance; PV; portal vein; PZQ; praziquantel; SD; standard deviation; SV; splenic vein; US; ultrasound;
مقالات ISI (ترجمه نشده)
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Keywords: Praziquantel; Mechanochemistry; Solid-state reactions; Polymorphism; Solubility; Bioactivity; Crystal structure solution; DFT-D calculations; Neglected tropical diseases; ASU; Asymmetric Unit; ATR-FTIR; Attenuated Total Reflectance Fourier Transform Infra
Keywords: SM; sphingomyelin; nSMase; neutral sphingomyelinase; ARA; arachidonic acid; IF; indirect membrane immunofluorescence; MBCD; methyl-β-cyclodextrin; PUFA; polyunsaturated fatty acid; EINS; elastic incoherent neutron scattering; QENS; quasi-elastic neutron
Keywords: PZQ; praziquantel; ART; artemether; NTD; neglected tropical disease; DALYs; disability adjusted life years; EPG; eggs per gram; WHO; World Health Organization; MDA; mass drug administration; MOHP; the Egyptian Ministry of Health and Population; UNDP; Unit
Keywords: BDD; boron-doped diamond; CFU; colony-forming units; CNFs; carbon nanofibres; COD; chemical oxygen demand; CT; computed tomography; EIS; electrochemical impedance spectroscopy; EF; electro-Fenton; EtAQ; 2-ethyl-9,10-anthraquinone; FTIR; Fourier transform
Keywords: Schistosomiasis; School-aged children; Diagnosis; Treatment; School-based actions; Community-based actions; AEs; adverse events; BMI; body mass index; CDC; Center of Disease Control; GCP; Good Clinical Practice; CONSORT; Consolidated Standards of Reportin
Keywords: CNS; central nervous system; DAT; dopamine transporter; GABA; gamma-aminobutyric acid; GAT; gamma-aminobutyric acid (GABA) transporter; GLT; glutamate transporter; iDAT; invertebrate dopamine transporter; NAT; noradrenaline transporter; NTT; neurotransmit
Evaluation of a novel micro-sampling device, Mitraâ¢, in comparison to dried blood spots, for analysis of praziquantel in Schistosoma haematobium-infected children in rural Côte d'Ivoire
Keywords: Cmax; maximal blood concentration; Tmax; time needed to reach maximal blood concentration; T1/2; half life of the drug; AUC; area under the concentration-time curve; DBS; dried blood spots; PZQ; praziquantel; PK; pharmacokinetics; SAC; school-aged childre
Calmodulins from Schistosoma mansoni: Biochemical analysis and interaction with IQ-motifs from voltage-gated calcium channels
Keywords: ANS; anilinonaphthalene-8-sulfonate; BS3; bis(sulfosuccinimidyl)suberate; CPZ; chlorpromazine; PZQ; praziquantel; rmsd; root mean square deviation; SmCaM1; one of the two calmodulins from S. mansoni; SmCaM2; one of the two calmodulins from S. mansoni; TFP
Sesquiterpenes effects on DNA of Schistosoma mansoni after in vivo treatment
Keywords: dpi; days post-infection; EO; essential oils; PZQ; praziquantel; RAPD; Random Amplified Polymorphic DNA; T-CP; trans-caryophyllene; α-HL; alpha-humulene; Genetic polymorphisms; RAPD-PCR; Sesquiterpenes; Schistosoma mansoni; Treatment;
In vitro schistosomicidal activity of the crude extract, fractions and Primin, the major active benzoquinone constituent from the leaves of Miconia willdenowii (Melastomaceae)
Keywords: COX-1 and COX-2; cyclooxygenases-1 and 2; NSAIDs; nonsteroidal anti-inflammatory drugs; NTDs; neglected tropical diseases; OCC; open column chromatography; PZQ; praziquantel; ROS; reactive oxygen species; TLC; thin layer chromatography; Miconia willdenowi
Simvastatin exerts antifibrotic effect and potentiates the antischistosomal effects of praziquantel in a murine model: Role of IL10
Keywords: IL-10; interleukin 10; PZQ; praziquantel; SIM; simvastatin; ALT; alanine amino transferase; Schistosoma mansoni; Simvastatin; Praziquantel; IL-10;
Initiating NTD programs targeting schistosomiasis and soil-transmitted helminthiasis in two provinces of the Democratic Republic of the Congo: Establishment of baseline prevalence for mass drug administration
Keywords: ALB; albendazole; CDC; centers for diseases control; DRC; Democratic Republic of the Congo; HRA; high risk adults; HZ; health zone; MDA; mass drug administration; NTD; neglected tropical diseases; POC-CCA; point of care circulating cathodic antigen; PZQ;
In vitro schistosomicidal and antiviral activities of Arctium lappa L. (Asteraceae) against Schistosoma mansoni and Herpes simplex virus-1
Keywords: AL; Arctium lappa extract; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; FBS; fetal bovine serum; HSV-1; Herpes simplex virus type 1; PZQ; praziquantel; RPMI 1640; Roswell Park Memorial Institute; UPLC-ESI-QTOF-MS; ultra high pres
Comparison of apoptosis between adult worms of Schistosoma japonicum from susceptible (BALB/c mice) and less-susceptible (Wistar rats) hosts
Keywords: S. japonicum; Schistosoma japonicum; TEM; transmission electron microscopy; TUNEL; fluorometric terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling; FCM; flow cytometry; RT-PCR; real-time polymerase chain reaction; PZQ; praziquantel; PBS
Unexpected solvent impact in the crystallinity of praziquantel/poly(vinylpyrrolidone) formulations. A solubility, DSC and solid-state NMR study
Keywords: Praziquantel (PubChem CID: 4891); PZQ; praziquantel; PVP; poly(vinylpyrrolidone); NMR; nuclear magnetic resonance; DSC; differential scanning calorimetry; SEM; scanning electron microscopy; PMs; physical mixtures; SDs; solid dispersions; Praziquantel; Pol
Nanoencapsulated curcumin and praziquantel treatment reduces periductal fibrosis and attenuates bile canalicular abnormalities in Opisthorchis viverrini-infected hamsters
Keywords: OV; Opisthorchis viverrini; CCA; cholangiocarcinoma; NEC; nanoencapsulated curcumin; PZQ; praziquantel; PDF; periductal fibrosis; BC; bile canaliculi; Cur; curcumin; ALT; alanine transaminase; MMP; matrix metalloproteinases; TIMP; tissue inhibitors of MMP
Evaluation of Echinostoma liei worm, metacercaria and redia antigens for schistosomiasis control
Keywords: Schistosomiasis; PZQ; Echinostoma liei; Worm burden; Oogram; Immunoglobulins;
Cardamonin, a schistosomicidal chalcone from Piper aduncum L. (Piperaceae) that inhibits Schistosoma mansoni ATP diphosphohydrolase
Keywords: Cardamom; Chalcone; SmATPDases; Piper aduncum; Apyrase; Schistosomicidal activity; PZQ; praziquantel; PaI; crude dichloromethane extract from inflorescences of P. aduncum; PaI-H; hexane fraction of the crude extract of P. aduncum; PaI-C; chloroform fracti
Elucidating the guest-host interactions and complex formation of praziquantel and cyclodextrin derivatives by 13C and 15N solid-state NMR spectroscopy
Keywords: PZQ; praziquantel; CD; cyclodextrin; β -CD; β -cyclodextrin; Me-β-CD; methyl-β-cyclodextrin; HP-β-CD; hydroxypropyl-β-cyclodextrin; XRPD; X-ray powder diffraction; CP/MA; Scross polarization/magic-angle spinning; TOSS; total suppression of spinning
Praziquantel efficacy against Brachylaima sp. metacercariae (Trematoda: Brachylaimidae) parasitizing the edible landsnail Cornu aspersum and its HPLC-MS/MS residue determination
Keywords: Brachylaima; Cornu aspersum; Praziquantel; Efficacy; HPLC-MS/MS; Brachylaimiasis; ADI; acceptable daily intake; CI; confidence intervals; CV; coefficient of variation; CVMP; Committee for Veterinary Medicinal Products; EMA; European Medicines Agency; HPLC
Mushroom lectin enhanced immunogenicity of HBV DNA vaccine in C57BL/6 and HBsAg-transgenic mice
Keywords: HBV; hepatitis B virus; POL; lectin purified from pleurotus ostreatus; HBVsAg-Tg; HBV surface antigen transgenic; DTH; delayed-type hypersensitivity; HBVsAb; HBV surface protein antibody; PZQ; praziquantel; rHBVsAg; recombinant HBV surface antigen; MTT; 3
LC-MS/MS method for the simultaneous quantitation of three active components derived from a novel prodrug against schistosome infection
Keywords: ARS; artesunate; DHA; dihydroartemisinin; ATM; artemether; PZQ; praziquantel; 10-OHPZQ; 10-hydroxypraziquantel; Prodrug; Artesunate; Dihydroartemisinin; 10-Hydroxypraziquantel; Pharmacokinetics;
Urine heme dipsticks are useful in monitoring the impact of Praziquantel treatment on Schistosoma haematobium in sentinel communities of Delta State, Nigeria
Keywords: SH; Schistosoma haematobium; DALY; disability adjusted life year; PZQ; praziquantel; MDA; mass drug administration; LGA; Local Government Area; CDD; community directed distributor; NVD; nurse visual diagnosis; Schistosomiasis; Praziquantel; Mass treatment
Thioredoxin glutathione reductase: Its role in redox biology and potential as a target for drugs against neglected diseases
Keywords: FAD; flavin adenine dinucleotide; Grx; glutaredoxin; GSH; glutathione; GSSG; glutathione disulfide; GR; glutathione disulfide reductase; PZQ; praziquantel; Sec; selenocysteine; SECIS; Sec insertion sequence; Trx; thioredoxin; TrxR; thioredoxin reductase;
Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility
Keywords: PZQ; praziquantel; Pgp; P-glycoprotein; ABC; ATP-binding-cassette; Schistosoma mansoni; P-glycoprotein; Multidrug resistance; Praziquantel; ABC transporter;