Keywords: KP; kynurenine pathway; IDO; indoleamine 2,3-dioxygenase; TDO2; tryptophan 2,3 dioxygenase (gene); TDO; tryptophan 2,3 dioxygenase (enzyme); KAT; kynurenine aminotransferase; KMO; kynurenine monooxigenase; Trp; tryptophan; KYN; L-kynurenine; KYNA; kynuren
مقالات ISI (ترجمه نشده)
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Keywords: 1-MT; 1-methyltryptophan; 3-HK; 3-hydroxykynurenine; 5-HT; serotonin; 5-HTP; 5-hydroxy-l-tryptophan; 5-HIAA; 5-hydroxyindoleatic acid; ACTH; adrenocorticotrophic hormone; AADC; aromatic l-amino acid descarboxylase; AA-NAT; aralkylamine N-acetyltransferase
Keywords: 1,2DMI; 1,2-dimethylindole; 2MI; 2-methylindole; AAS; atomic absorption spectroscopy; ABDC; 2-aminobenzene-1,4-dicarboxylate; AFM; atomic force microscope; ASA; p-arsanilic acid; ATR-FTIR; attenuated total reflectance Fourier transformed infrared spectros
Keywords: Depressive disorder; Inflammation; ECT; Immune; Cortisol; ACTH; Adrenocorticotropic hormone; AVP; arginine vasopressin; BDI; Beck Depression Inventory; BL-BT; Bilateral-Bitemporal; BP; Bipolar Disorders; CMI test; serotonin uptake inhibitor clomipramine;
Keywords: 3-HK; 3-hydroxykynurenine; 6-OHDA; 6-hydroxydopamine; A; Amygdala; ACMSD; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; AD; Alzheimer's disease; AD; Anterodorsal nucleus (Thalamus); α-syn; Alpha-synuclein; CCL2; Chemokine (CC motif) ligand 2;
Keywords: 3-HAO; 3-hydroxyanthranilic acid dioxygenase; 3-HK; 3-hydroxykynurenine; 5-HT; serotonin; IDO; indoleamine 2,3-dioxygenase; KATs; kynurenine aminotransferases; KMO; kynurenine 3-monooxygenase; KYNA; kynurenic acid; KYNU; kynureninase; QUIN; quinolinic aci
Keywords: PPI; prepulse inhibition; ISI; interstimulus interval; QUIN; quinpirole; NAc; nucleus accumbens; Neonatal quinpirole; Dopamine D2 receptor; Prepulse inhibition; Sensorimotor gating; Interstimulus interval; Rats;
Keywords: CNS; central nervous system; INS-1; insulin secreting β-cell line originated from a rat insulinoma; GK rat; Goto-Kakizaki rat; NOD mouse; non-obese diabetic mouse; TKP; tryptophan/kynurenine pathway; Trp; tryptophan; KYN; kynurenine; 3HK; 3-OH-kynureni
Keywords: ADX; adrenalectomized; ASD; autism spectrum disorders; BD; bipolar disorder; CSF; cerebrospinal fluid; DAMPs; damage-associated molecular patterns; FS; forced swimming; HDACi; histone deacetylase inhibitor; HSP; heat shock protein; IDO; indoleamine 2,3 di
Keywords: AASA; α-aminoadipic semialdehyde; ANT; adenine nucleotide translocator; Alam; alamethicin; BSA; bovine serum albumin; CAT; catalase; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; CoQ; coenzyme Q10; CP; chlorpromazine; CsA; cyclosporin A; DTT; dithioth
Keywords: α7nACh; α7 nicotinic acetylcholine; ANOVA; analysis of variance; KYNA; kynurenic acid; NMDA; N-methyl-d-aspartate; QUIN; 2,3-pyridinedicarboxylic acid; TRP; tryptophan; stress; kynurenic acid; α7nACh receptor; NMDA receptors; chick;
Keywords: 5-HIAA; 5 hydroxyindoleacetic acid; 5-HT; serotonin; 5-HTT; 5-HT transporter; ACTH; adrenocorticotropic hormone; AIAQ; anger irritability and assault questionnaire; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BCG; bacille Calmette-Gueri
Apelin, a promising target for Alzheimer disease prevention and treatment
Keywords: Alzheimer disease; Apelin; Amyloid beta; Central nervous system; Oxidative stress; AAA; Abdominal aortic aneurysm; ABCA1; ATP-binding cassette transporter A1; ACE; Angiotensin converting enzyme; ACh; Acetylcholine; AChE; Acetyl choline esterase; AD; Alzhe
Linking the biological underpinnings of depression: Role of mitochondria interactions with melatonin, inflammation, sirtuins, tryptophan catabolites, DNA repair and oxidative and nitrosative stress, with consequences for classification and cognition
Keywords: Major depressive disorder; Oxidative and nitrosative stress; Kynurenine; Aryl hydrocarbon; Immune-inflammation; Mitochondria; Pathophysiology; Melatonin; Treatment; Classification; Cognition; 3-OH-ANA; 3-hydroxyanthranillic acid; 3-OH-Kyn; 3-hydroxykynure
Apocynin protects against neurological damage induced by quinolinic acid by an increase in glutathione synthesis and Nrf2 levels
Keywords: APO; Apocynin; ATP; adenosine triphosphate; CDNB; 1-choloro-2,4-dinitrobenzene; EDTA; ethylenediamine tetraacetic acid; GPx; glutathione peroxidase; GSH; glutathione; GST; glutathione-S-transferase; NDA; 2,3-naphthalenedicarboxaldehyde; NOX; NADPH oxidase
Research PaperStrength of cholinergic tone dictates the polarity of dopamine D2 receptor modulation of striatal cholinergic interneuron excitability in DYT1 dystonia
Keywords: ACh; acetylcholine; AChE; acetylcholinesterase; ChI; cholinergic interneurons; D2R; dopamine D2 receptors; mAChR; muscarinic receptors; Oxo; oxotremorine; Quin; quinpirole; Neo; neostigmine; TorA; torsinA; Dystonia; DYT1; Dorsal striatum; Cholinergic inte
Human T cells in silico: Modelling their electrophysiological behaviour in health and disease
Keywords: ASSC; amiloride-sensitive Na+ channel; CRAC; Ca2+-release activated Ca2+ channel; HCN; hyperpolarization-activated, cyclic nucleotide-gated cation channel; I-V; current-voltage relationship; K2P; two pore domain K+ channel; KCa3.1; intermediate conduc
Decrease of neocortical paired-pulse depression in GAERS and possible implication of gap junctions
Keywords: ACSF; artificial cerebrospinal fluid; CBX; carbenoxolone; CNQX; 6cyano-7-nitro-quinoxaline-2,3-dione disodium salt; CPP; 3,3-(2-carboxypiperazine-4-yl)-propylphosphonate; GAERS; Genetic Absence Epilepsy Rat from Strasbourg; GJ; gap junction; GZA; glycyrrh
Abnormal involuntary movement (AIM) expression following D2 dopamine agonist challenge is determined by the nature of prior dopamine receptor stimulation (priming) in 6-hydroxydopamine lesioned rats
Keywords: 6-OHDA; 6-hydroxydopamine; AIMs; abnormal involuntary movements; Apo; apomorphine; i.p.; intraperitoneal; l-Dopa; l-3,4-dihydroxyphenylalanine; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PD; Parkinson's Disease; SKF; SKF38393; TH; tyrosine hydrox
Post-ischemic treatment with L-kynurenine sulfate exacerbates neuronal damage after transient middle cerebral artery occlusion
Keywords: 3-HK; 3-hydroxykynurenine; CNS; central nervous system; dMCA; distal middle cerebral artery; dMCAO; distal middle cerebral artery occlusion; EEG; electroencephalography; I/H; ischemic/hypoxic; KYNA; kynurenic acid; L-KYNs; L-kynurenine sulfate; NDS; norma
A complementary diffusion tensor imaging (DTI)-histological study in a model of Huntington's disease
Keywords: Huntington's disease; Rat model; QUIN; MRI; DTI;
Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: Focus on individual differences
Keywords: UCMS; unpredictable chronic mild stress; TRP; tryptophan; KYN; kynurenine, 5-HT, serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; KP; kynurenine pathway; 3HK; 3-hydroxykynurenine; QUIN; quinolinic acid; KYNA; kynurenic acid; IDO; indoleamine-2,3-dioxygenase
Research reportPeripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression
Keywords: UCMS; unpredictable chronic mild stress; TRP; tryptophan; KYN; kynurenine; 5-HT; serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; KP; kynurenine pathway; 3HK; 3-hydroxykynurenine; QUIN; quinolinic acid; ANA; anthranilic acid; 3-HANA; 3-hydroxyanthranilic ac
Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease
Keywords: 3-HK; 3-hydroxykynurenine; 3-HAD; 3-hydroxyanthranilic acid dioxygenase; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AP5; d-amino-phosphonopentanoic acid; AP7; d-amino-phosphonoheptanoic acid; CNS; central nervous system; HD; Huntington's
Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials
Keywords: Ery A, erythromycin A; MLSB, macrolide-lincosamide-streptogramin B; EDC HCl, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; PyTFA, pyridinium trifluoroacetateKetolides; Macrolide antibiotics; 15-Membered 8a- and 9a-azahomoerythromycins; Quin
Radicals in organic synthesis. Part 1
Keywords: (S,S)-BDPP; (2S,4S)-2,4-bis(diphenylphosphino)pentane; ABCVA; 4,4â²-azobis(4-cyanovaleric acid); ACCN; 1,1â²-azobis(cyclohexanecarbonitrile); AIBN; azobisisobutyronitrile; AMBN; azobismethylisobutyronitrile or 2-(1-cyano-1-methyl-propylazo)-2-methyl-but
Relative contribution of rat cytochrome P450 isoforms to the metabolism of caffeine: The pathway and concentration dependence
Keywords: CYP; P450; cytochrome P450; FMO; flavin-containing monooxygenase; HPLC; high performance liquid chromatography; αNF; α-naphthoflavone; SULF; sulfaphenazole; CIM; cimetidine; QUIN; quinine; trans-DCE; trans-1,2-dichloroethylene; ERY; erythromycin; Km; th
Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: Protective role of iron porphyrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III)
Keywords: excitotoxic damage; peroxynitrite; oxidative/nitrosative stress; NMDA receptor; iron porphyrinate; neuroprotection; ANOVA; analysis of variance; APM; apomorphine; Fe(TPPS); 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III); F.U.; fluorescent
HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations
Keywords: Disorders of the nervous system; Infectious diseases; HIV; human immunodeficiency virus; HIVD; human immunodeficiency virus-dementia; AD; Alzheimer's disease; CSF; cerebrospinal fluid; ROS; reactive oxygen species; HNE; 4-hydroxy-2-nonenal; GSH; glutathio
Cytokines and major depression
Keywords: ACh; acetylcholine; ACTH; adrenocorticotropic hormone; ANS; autonomous nervous system; APP; acute-phase protein; BBB; blood-brain barrier; CAA; competing amino acid; CMS; chronic mild stress; CNS; central nervous system; CRH; corticotropin-releasing hor