دانلود مقالات ISI درباره اسید کینولینیک + ترجمه فارسی

Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues

Keywords: اسید کینولینیک; ADPR; ADP ribose; ARTs; ADP ribose transferases; ARTD1; poly-(ADP ribose) polymerase 1; NAADP; nicotinic acid adenine dinucleotide phosphate; CR; calorie restriction; PAR; poly-(ADP ribose); PGC-1; peroxisome proliferator-activated receptor-γ coactivator

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

BDNF in quinolinic acid lesioned rats after bone marrow cells transplant

Keywords: اسید کینولینیک; Brain-derived neurotrophic factor (BDNF); Bone marrow stem cells (BMC); Huntington's disease (HD); Quinolinic acid; Transplant;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Reduced microglial immunoreactivity for endogenous NMDA receptor agonist quinolinic acid in the hippocampus of schizophrenia patients

Keywords: اسید کینولینیک; Schizophrenia; Microglia; Quinolinic acid; Glutamate; Hippocampal formation; Hippocampus;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The absence of indoleamine 2,3-dioxygenase expression protects against NMDA receptor-mediated excitotoxicity in mouse brain

Keywords: اسید کینولینیک; HD; Huntington's disease; Ido1; indoleamine 2,3-dioxygenase (gene); Tdo2; tryptophan 2,3-dioxygenase (gene); Ido2; indoleamine 2,3-dioxygenase 2 (gene); KP; kynurenine pathway; SP; serotonin pathway; Kyn; kynurenine; LC-MS/MS; liquid chromatography tandem

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The lateral neostriatum is necessary for compensatory ingestive behaviour after intravascular dehydration in female rats

Keywords: اسید کینولینیک; HD; Huntington's disease; QA; quinolinic acid; PEG; poly-ethylene glycol; NADPHd; nicotinamide adenine dinucleotide phosphate diaphorase; NaCl; sodium chloride; Striatum; Intracellular dehydration; Intravascular dehydration; Huntington's disease; Poly

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Mutant huntingtin affects endocytosis in striatal cells by altering the binding of AP-2 to membranes

Keywords: اسید کینولینیک; AP-2; adaptor complex-2; CCVs; clathrin coated vesicles; CME; clathrin-mediated endocytosis; HIP-1; huntingtin interacting protein-1; htt; huntingtin; mHtt; mutated huntingtin; QA; quinolinic acid; Endocytosis; Clathrin coated vesicles; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Post-ischemic treatment with L-kynurenine sulfate exacerbates neuronal damage after transient middle cerebral artery occlusion

Keywords: اسید کینولینیک; 3-HK; 3-hydroxykynurenine; CNS; central nervous system; dMCA; distal middle cerebral artery; dMCAO; distal middle cerebral artery occlusion; EEG; electroencephalography; I/H; ischemic/hypoxic; KYNA; kynurenic acid; L-KYNs; L-kynurenine sulfate; NDS; norma

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2013 سفارش ترجمه

Lesions of the dorsomedial striatum impair formation of attentional set in rats

Keywords: اسید کینولینیک; Behavioural flexibility; Striatum; Set shifting; Reversal learning; Quinolinic acid

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of acetylcholinesterase activities and some pro-oxidant induced lipid peroxidation in rat brain by two varieties of ginger (Zingiber officinale)

Keywords: اسید کینولینیک; Red ginger; White ginger; Alzheimer's disease; Acetylcholinesterase; Sodium nitroprusside; Quinolinic acid; Rat; Brain

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Social isolation rearing in rats alters plasma tryptophan metabolism and is reversed by sub-chronic clozapine treatment

Keywords: اسید کینولینیک; Tryptophan metabolism; Social isolation rearing; Clozapine; Schizophrenia; Quinolinic acid; Kynurenic acid; Anti-inflammatory; AntioxidantSIR, social isolation rearing; DA, dopamine; ROS, reactive oxygen species; KYNA, kynurenic acid; QA, quinolinic acid;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Gas chromatography/tandem mass spectrometry detection of extracellular kynurenine and related metabolites in normal and lesioned rat brain

Keywords: اسید کینولینیک; 3-Hydroxykynurenine; Microdialysis; Quinolinic acid; Selective reaction monitoring; Tandem mass spectrometry; Tryptophan;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Regular ArticleSignaling mechanisms downstream of quinolinic acid targeting the cytoskeleton of rat striatal neurons and astrocytes

Keywords: اسید کینولینیک; Quinolinic acid; Hyperphosphorylation; Intermediate filaments; Cell signaling; Calcium; Glutamate receptors; Cyclin-dependent kinase 5;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis

Keywords: اسید کینولینیک; Human NaPRT; Enzyme kinetics; Homology modeling; Molecular docking; Site-directed mutagenesis; DHAP; dihydroxyacetone phosphate; G3P; glyceraldehyde 3-phosphate; IPTG; isopropyl β-d-1-thiogalactopyranoside; Na; nicotinic acid; Nam; nicotinamide; NamR; ni

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Research reportNMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways

Keywords: اسید کینولینیک; NMDA preconditioning; Signaling pathways; PI3K; PKA; Neuroprotection; Quinolinic acid;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

MinireviewCell signaling in NMDA preconditioning and neuroprotection in convulsions induced by quinolinic acid

Keywords: اسید کینولینیک; Preconditioning; N-methyl-d-aspartate; Neuroprotection; Glutamatergic excitotoxicity; Quinolinic acid; NMDA receptor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats

Keywords: اسید کینولینیک; Excitotoxicity; Mitochondrial dysfunction; Huntington's disease; Oxidative stress; Quinolinic acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: Focus on individual differences

Keywords: اسید کینولینیک; UCMS; unpredictable chronic mild stress; TRP; tryptophan; KYN; kynurenine, 5-HT, serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; KP; kynurenine pathway; 3HK; 3-hydroxykynurenine; QUIN; quinolinic acid; KYNA; kynurenic acid; IDO; indoleamine-2,3-dioxygenase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Licofelone attenuates quinolinic acid induced Huntington like symptoms: Possible behavioral, biochemical and cellular alterations

Keywords: اسید کینولینیک; COX; cyclo-oxygenase; LOX; lipoxygenase; HD; Huntington disease; PG; Prostaglandin; QA; Quinolinic acid; SOD; Super oxide dismutase; SDH; Succinate dehydrogenase; TNF; Tumor necrosis factor; Antioxidant; Licofelone; Mitochondrial dysfunction; Neurotoxicit

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Inflammation-associated depression: From serotonin to kynurenine

Keywords: اسید کینولینیک; Depression; Inflammation; Interferon-alpha; Indoleamine 2,3-dioxygenase; Tryptophane; Kynurenine; Quinolinic acid; Kynurenic acid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Research ReportAttenuation of proinflammatory cytokines and apoptotic process by verapamil and diltiazem against quinolinic acid induced Huntington like alterations in rats

Keywords: اسید کینولینیک; Calcium channel blockers; Inflammatory cytokines; Motor dysfunction; Oxidative stress; Quinolinic acid;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

The unsolved puzzle of neuropathogenesis in glutaric aciduria type I

Keywords: اسید کینولینیک; 3-OHGA; 3-hydroxyglutaric acid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APV; D-2-amino-5-phophonovalerate; BBB; blood-brain barrier; BCB; blood-cerebrospinal fluid barrier; CAT; catalase; CHO; Chinese hamster ovary; CK; creatine k

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

An analytical method for the measurement of acid metabolites of tryptophan-NAD pathway and related acids in urine

Keywords: اسید کینولینیک; Quinolinic acid; Piconilic acid; Nicotinic acid; Pyridylacetic acid; Urine; Mixed-mode SPE; LC/MS

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

On the early toxic effect of quinolinic acid: Involvement of RAGE

Keywords: اسید کینولینیک; Receptor-for-advanced-glycation-end-products; Neurotoxicity; Quinolinic acid; NF-κB; Oxidative stress; Neurodegeneration; Huntington's disease;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells

Keywords: اسید کینولینیک; Quinolinic acid; PK11195; Glucose metabolism; Glial cell; Rat brain

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Differential involvement of prefrontal cortex, striatum, and hippocampus in DRL performance in mice

Keywords: اسید کینولینیک; Time estimation; Behavioral inhibition; Decision making; Executive function; Ibotenic acid; Quinolinic acid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Research reportPeripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression

Keywords: اسید کینولینیک; UCMS; unpredictable chronic mild stress; TRP; tryptophan; KYN; kynurenine; 5-HT; serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; KP; kynurenine pathway; 3HK; 3-hydroxykynurenine; QUIN; quinolinic acid; ANA; anthranilic acid; 3-HANA; 3-hydroxyanthranilic ac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Kynurenine and its metabolites in Alzheimer's disease patients

Keywords: اسید کینولینیک; Alzheimer's disease; tryptophan; kynurenine; kynurenic acid; quinolinic acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats

Keywords: اسید کینولینیک; Quinolinic acid; Intermediate filaments; Excitotoxicity; Oxidative stress; PhosphoNFLSer55

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Neuroprotective effects of (−)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition

Keywords: اسید کینولینیک; Apoptosis; EGCG; GSK-3β; Nitric oxide; PI3K; Quinolinic acid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats

Keywords: اسید کینولینیک; COX, cyclooxygenase; LPO, lipid peroxidation; NMDAr, N-methyl-d-aspartate receptors; QA, quinolinic acid; ROS, reactive oxygen speciesCyclooxygenase; Mitochondria; Nimesulide; Oxidative stress; Quinolinic acid; Rofecoxib

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease

Keywords: اسید کینولینیک; 3-HK; 3-hydroxykynurenine; 3-HAD; 3-hydroxyanthranilic acid dioxygenase; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AP5; d-amino-phosphonopentanoic acid; AP7; d-amino-phosphonoheptanoic acid; CNS; central nervous system; HD; Huntington's

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Kynurenine, quinolinic acid—The new factors linked to carotid atherosclerosis in patients with end-stage renal disease

Keywords: اسید کینولینیک; Carotid atherosclerosis; End-stage renal disease; Kynurenine; Kynurenic acid; Quinolinic acid; Inflammation; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Spermine improves recognition memory deficit in a rodent model of Huntington’s disease

Keywords: اسید کینولینیک; Spermine; Quinolinic acid; Striatum; Huntington’s disease; Memory; Object discrimination; Astrocytes

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Impact of co administration of selenium and quinolinic acid in the rat's brain

Keywords: اسید کینولینیک; Selenium; Quinolinic acid; Acetyl cholinesterase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria

Keywords: اسید کینولینیک; Cerebral malaria; Indoleamine 2,3-dioxygenase; Kynurenic acid; Kynurenine pathway; Picolinic acid; Quinolinic acid; Tryptophan metabolism

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Thalidomide inhibition of vascular remodeling and inflammatory reactivity in the quinolinic acid–injected rat striatum

Keywords: اسید کینولینیک; vascular remodeling; excitotoxicity; quinolinic acid; thalidomide; microgliosisAD, Alzheimer's disease; BBB, blood–brain barrier; CMC, carboxymethylcellulose; GFAP, glial fibrillary acidic protein; IL, interleukin; ir, immunoreactivity; NeuN, neuronal nuc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: Role in excitotoxicity

Keywords: اسید کینولینیک; Calcineurin A; Calcineurin B; Conditional mouse model; Huntingtin; Quinolinic acid; R6/1; Striatum

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

AAV-mediated expression of Bcl-xL or XIAP fails to induce neuronal resistance against quinolinic acid-induced striatal lesioning

Keywords: اسید کینولینیک; Anti-apoptotic proteins; Bcl-xL; XIAP; AAV-vectors; Quinolinic acid; Neuroprotection; Motor function; Striatum

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions

Keywords: اسید کینولینیک; CB1; BDNF; Huntington’s disease; quinolinic acid; confocal microscopy; ratBDNF, brain-derived neurotrophic factor; CB1, type-1 cannabinoid receptor; CLSM, confocal laser scanning microscope; EDTA, ethylenediamine tetraacetic acid; ELISA, enzyme-linked imm

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Intact intracortical microstimulation (ICMS) representations of rostral and caudal forelimb areas in rats with quinolinic acid lesions of the medial or lateral caudate-putamen in an animal model of Huntington's disease

Keywords: اسید کینولینیک; Caudate-putamen; Striatum; Huntington's model; Intracortical microstimulation (ICMS); Quinolinic acid; Motor cortex; Motor map; Rat; Caudal forelimb area (CFA); Rostral forelimb area (RFA)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Changes in pyridine metabolism profile during growth of trigonelline-forming Lotus japonicus cell cultures

Keywords: اسید کینولینیک; NaAD; nicotinate adenine nucleotide; NaMN; nicotinate mononucleotide; NaPRT; nicotinate phosphoribosyltransferase; Na-riboside; nicotinate riboside; NMN; nicotinamide mononucleotide; N-riboside; nicotinamide riboside; Lotus japonicus; Leguminosae; Biosynt

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Research reportEffect of quinolinic acid-induced lesions of the subthalamic nucleus on performance on a progressive-ratio schedule of reinforcement: A quantitative analysis

Keywords: اسید کینولینیک; Subthalamic nucleus; Lesion; Quinolinic acid; Progressive-ratio schedule; Reinforcer efficacy; Rat;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Measurement of the 14N nuclear quadrupole resonance frequencies by the solid effect

Keywords: اسید کینولینیک; N-14; Quadrupole resonance; Double resonance; Histamine; Quinolinic acid;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Microglial activation, macrophage infiltration, and evidence of cell death in the fetal brain after uteroplacental administration of lipopolysaccharide in sheep in late gestation

Keywords: اسید کینولینیک; fetal sheep brain; macrophage; microglia; quinolinic acid; uteroplacental circulation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

Keywords: اسید کینولینیک; Brain-derived neurotrophic factor; Excitotoxicity; Postsynaptic density; Quinolinic acid; Synaptic dysfunction; Huntington’s disease

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions

Keywords: اسید کینولینیک; Huntington's disease; Embryonic stem cells; Quinolinic acid; Transplantation; Neuronal precursor

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Characterization of tryptophan-niacin metabolism in rats fed with an excessive tryptophan diet

Keywords: اسید کینولینیک; Quinolinic acid; N1-methylnicotinamide; N1-methyl-2-pyridone-5-carboxamide; Tryptophan; Niacin; N1-methyl-4-pyridone-3-carboxamide;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Mass spectrometric detection of quinolinic acid in microdissected Alzheimer's disease plaques

Keywords: اسید کینولینیک; Quinolinic acid; Alzheimer's disease; Senile plaques; Hippocampus; Laser capture microdissection; Neuroinflammation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Effect of quinolinic acid on gene expression in human astrocytes: Implications for Alzheimer's disease

Keywords: اسید کینولینیک; Alzheimer's disease; Inflammation; Quinolinic acid; Human adult astrocytes; Kynurenine pathway; IL1β; IL-6; S100β; GFAP; GS; TNFα; IFNγ

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

High throughput analysis of tryptophan metabolites in a complex matrix using capillary electrophoresis coupled to time-of-flight mass spectrometry

Keywords: اسید کینولینیک; Tryptophan; Kynurenine; Kynurenic acid; Quinolinic acid; Picolinic acid; Capillary electrophoresis; Mass spectrometry; Time-of-flight; Complex matrix; Cerebrospinal fluid

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه