Keywords: رانولازین; Atrial fibrillation; Cardiac surgery; Metaanalysis; Ranolazine; Post-operative atrial fibrillation;
مقالات ISI رانولازین (ترجمه نشده)
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Keywords: رانولازین; Ranolazine; Angina; Diabetes; Atrial fibrillation; Pulmonary arterial hypertension; Diastolic dysfunction;
Keywords: رانولازین; Ranolazine; Late sodium current; Atrial fibrillation; Meta-analysis;
Keywords: رانولازین; Angina; Cost-effectiveness; Cost-utility; Economic evaluation; Ranolazine; Review
Keywords: رانولازین; alginate; hydroxypropylcellulose; ranolazine; polymeric pellets; enteric coating;
Keywords: رانولازین; ACh; acetylcholine; AF; atrial fibrillation; AP; action potential; APD; action potential duration; [Ca2Â +]i; intracellular Ca2Â + concentration; CaMKII; Ca2Â +/calmodulin-dependent protein kinase II; DAD; delayed afterdepolarization; EAD; early afterdepo
Keywords: رانولازین; Isquemia-reperfusión; Cardioprotección; Ca2+; Ranolazina; Ischemia-reperfusion; Cardioprotection Ca2+; Ranolazine; INaL; corriente de Na+ tardÃa; IR; isquemia-reperfusión; NCX; intercambiador de Na+/Ca2+;
Keywords: رانولازین; Heart failure with preserved ejection fraction; Ranolazine; Diastolic dysfunction; Dahl salt-sensitive rats;
Keywords: رانولازین; Atrial fibrillation; Heart failure; Anti-arrhythmic therapy; Ranolazine; Dronedarone; Electrophysiology;
Keywords: رانولازین; Antiarrhythmic drug therapy; Atrial fibrillation; Late sodium current channel blocker; Ranolazine; Ventricular arrhythmias;
Keywords: رانولازین; Cardiovascular effects; Non-anginal; Ranolazine; Randomized trials;
Keywords: رانولازین; Ranolazine; Microvascular dysfunction; Primary microvascular angina; Cardiac X syndrome;
Keywords: رانولازین; Celecoxib; Indomethacin; Atrial fibrillation; Pulmonary vein; Atrium; Ranolazine;
Keywords: رانولازین; AERP; atrial effective refractory period; AF; atrial fibrillation; AFL; atrial flutter; BB; Bachmann bundle; CL; cycle length; CT; conduction time; ECG; electrocardiographic; IKr; rapidly activating delayed rectifier potassium current; INa; sodium current
Keywords: رانولازین; Type 2 diabetes mellitus; Endothelial function; Ranolazine;
Keywords: رانولازین; Heart failure; Hypertrophy; Arrhythmias; INaL; CaMKII; Ranolazine;
Differential regulation of tefluthrin and telmisartan on the gating charges of INa activation and inactivation as well as on resurgent and persistent INa in a pituitary cell line (GH3)
Keywords: رانولازین; AP; action potential; HEK; human embryonic kidney; I-V; current versus voltage; INa; voltage-gated Na+ current; INa(P); persistent INa; INa(R); resurgent INa; λ; rate constant; LIM; d-limonene; NaV channel; voltage-gated Na+ channel; Ran; ranolazine; S
Eleclazine exhibits enhanced selectivity for long QT syndrome type 3-associated late Na+ current
Keywords: رانولازین; Sodium channel; Eleclazine; Ranolazine; Long QT syndrome; Brugada syndrome;
Diffuse reflectance infrared fourier transform spectroscopy (DRIFTS) application in pharmaceutical analysis: Method for quantification of ranolazine in tablet dosage form
Keywords: رانولازین; DRIFTS; Ranolazine; Analytical method development; Quantitative analysis; Tablet dosage form; Pharmaceutical analysis;
Complexity of ranolazine and phenytoin use in an infant with long QT syndrome type 3
Keywords: رانولازین; Long QT; Ranolazine; Sodium channel; Pharmacology; Phenytoin; Torsades de pointes;
Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial
Keywords: رانولازین; chest pain; emergency department; microvascular angina; PET; randomized controlled trial; ranolazine;
Impact of ranolazine on coronary microvascular dysfunction (MICRO) study
Keywords: رانولازین; Coronary; Microvascular; Dysfunction; Ranolazine;
Development of ethosomal gel of ranolazine for improved topical delivery: In vitro and ex vivo evaluation
Keywords: رانولازین; Ranolazine; Ethosome; Gel; Permeation;
Discovery of triazolopyridine GS-458967, a late sodium current inhibitor (Late INai) of the cardiac NaV 1.5 channel with improved efficacy and potency relative to ranolazine
Keywords: رانولازین; Late INa current inhibitor; GS-458967; Anti-arrhythmic; Ranolazine; Ventricular arrhythmia
Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazine
Keywords: رانولازین; Late INa current inhibitor; GS-462808; Anti-ischemic; Ranolazine; Angina
Gene expression profiling reveals Nef induced deregulation of lipid metabolism in HIV-1 infected T cells
Keywords: رانولازین; HIV-1; Nef; Microarray; Gene expression; Lipid metabolism; Atorvastatin; Ranolazine;
Ranolazine reduces angina frequency and severity and improves quality of life: Observational study in patients with chronic angina under ranolazine treatment in Greece (OSCAR-GR)
Keywords: رانولازین; Chronic stable angina; Observational study; Ranolazine; Quality of life
Ranolazine vs phenytoin: greater effect of ranolazine on the transient Na+ current than on the persistent Na+ current in central neurons
Keywords: رانولازین; Ranolazine; Phenytoin; Voltage-gated Na+ channels; Persistent current; Antiepileptic drugs; Patch-clamp; AEDs; antiepileptic drugs; INaT; transient sodium current; INaP; persistent sodium current; INaP_STEP; INaP measured with step protocol; INaW; window
Inhibition of late sodium current attenuates ionic arrhythmia mechanism in ventricular myocytes expressing LaminA-N195K mutation
Keywords: رانولازین; Lamin A/C mutation; Cardiac arrhythmia; Late sodium current; Ventricular myocyte; Ranolazine;
Ranolazine improves oxidative stress and mitochondrial function in the atrium of acetylcholine-CaCl2 induced atrial fibrillation rats
Keywords: رانولازین; Ranolazine; Atrial fibrillation; Mitochondrial function; Akt/mTOR;
Antiarrhythmic properties of ranolazine: A review of the current evidence
Keywords: رانولازین; Atrial fibrillation; Late sodium current; Peak sodium current; Ranolazine; Ventricular tachycardia;
Cardiac late Na+ current: Proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress
Keywords: رانولازین; AP; action potential; APD; action potential duration; ATX-II; anemone toxin II; [Ca2+]i; intracellular calcium concentration; CaMKII; Ca2+/calmodulin-dependent protein kinase II; DAD; delayed afterdepolarization; EAD; early afterdepolarization; ICa-L; L-t
Synergistic antiarrhythmic effect of combining inhibition of Ca2+-activated K+ (SK) channels and voltage-gated Na+ channels in an isolated heart model of atrial fibrillation
Keywords: رانولازین; ACh; acetylcholine; aERP; atrial effective refractory period; AF; atrial fibrillation; APD; action potential duration; ICA; N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine; MAP; monophasic action potential; SK; small conductance Ca2+-activated K+; STV; s
Ranolazine in the treatment of atrial fibrillation: Results of the dose-ranging RAFFAELLO (Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion) study
Keywords: رانولازین; AF; atrial fibrillation; CI; confidence interval; ECV; electrical cardioversion; INa; sodium current; ITT; intention to treat; TESS; treatment emergent signs and symptoms; TT-ECG; transtelephonic electrocardiogram; Antiarrhythmic drug; Atrial fibrillation
Ranolazine inhibition of hERG potassium channels: Drug-pore interactions and reduced potency against inactivation mutants
Keywords: رانولازین; Antiarrhythmic; Docking; hERG; Lidocaine; QT interval; Ranolazine;
The late Na current as a therapeutic target: Where are we?
Keywords: رانولازین; INa,late; Ischemia; Angina; Heart failure; Arrhythmias; Ranolazine;
Evaluation of Ranolazine in Patients With Type 2 Diabetes Mellitus and Chronic Stable Angina: Results From the TERISA Randomized Clinical Trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina)
Keywords: رانولازین; clinical trial; coronary artery disease; diabetes; ranolazine; stable angina; CAD; coronary artery disease; late INa; late sodium current; SF-36; Medical Outcomes Short Form-36; SL NTG; sublingual nitroglycerin; T2DM; type 2 diabetes mellitus;
The potential contribution of ranolazine to Torsade de Pointe
Keywords: رانولازین; Ranolazine; Prolonged QT interval; Torsade de Pointes;
Ranolazine for the treatment of refractory angina in a veterans population
Keywords: رانولازین; Ranolazine; Refractory angina; Drug therapy; Veterans Affairs;
Long-term nerve excitability changes by persistent Na+ current blocker ranolazine
Keywords: رانولازین; I/V; current-threshold relationship; Nap; persistent Na+ current; RC; recovery cycle; SDTC; strength-duration time constant; SNAP; sensory nerve action potential; TE; threshold electrotonus; Axonal excitability; Sensory nerve; Persistent Na+ current; Ra
Cardiovascular PharmacologyEffect of ranolazine on rat intrarenal arteries in vitro
Keywords: رانولازین; Ranolazine; Intrarenal artery; Vasoconstriction; Adrenoceptor; L-type Ca2Â + current;
Development and validation of a sensitive U-HPLC–MS/MS method with electrospray ionization for quantitation of ranolazine in human plasma: Application to a clinical pharmacokinetic study
Keywords: رانولازین; Ranolazine; U-HPLC–ESI-MS/MS; Human plasma; Pharmacokinetics
Development and validation of a sensitive LC–MS/MS assay for simultaneous quantitation of ranolazine and its three metabolites in human plasma
Keywords: رانولازین; Liquid chromatography–tandem mass spectrometry; Ranolazine; Metabolites; Pharmacokinetics
Ranolazine stabilizes cardiac ryanodine receptors: A novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2
Keywords: رانولازین; Ranolazine; Action potential durations; Cycle length; Early afterdepolarizations; Torsades de pointes; Long QT type 2; Intracellular free calcium; Sarcoplasmic reticulum; Cardiac ryanodine receptor; Open probability; Shannon-Puglisi model; Mahajan UCLA mo
Damage to mitochondrial complex I during cardiac ischemia reperfusion injury is reduced indirectly by anti-anginal drug ranolazine
Keywords: رانولازین; Complex I; Mitochondrion; IR injury; Ranolazine; EPR; Heart
Pathophysiology of the cardiac late Na current and its potential as a drug target
Keywords: رانولازین; ATX-II; anemonia sulcata toxin; AP-A,Q; anthopleurin A, Q; hERG; human Ether-a-go-go Related Gene, KV11.1; INaT; transient (T) Na+ current; INaL; late (L) Na+ current; LQT(3); Long QT syndrome (variant 3); STX; saxitoxin; TTX; tetrodotoxin; Late Na curren
Role of ranolazine in angina, heart failure, arrhythmias, and diabetes
Keywords: رانولازین; Ranolazine; Late Na current; Ca overload; Ischemia; Angina; Atrial fibrillation; Heart failure; Arrhythmias; Diabetes
Antifibrillatory effect of ranolazine during severe coronary stenosis in the intact porcine model
Keywords: رانولازین; Antiarrhythmic agents; Myocardial ischemia; Sodium; T-wave alternans; Ranolazine; Ventricular fibrillation thresholdAPD, action potential duration; LAD, left anterior descending; MMA, modified moving average; TWA, T-wave alternans; VF, ventricular fibrill
Preparation and Evaluation of Mixture of Eudragit and Ethylcellulose Microparticles Loaded with Ranolazine for Controlled Release
Keywords: رانولازین; Ethyl cellulose; eudragit; kinetic drug release; microparticles; ranolazine;
Cardiovascular PharmacologyClass I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations
Keywords: رانولازین; Ranolazine; Action potential; Sodium channel; Electrophysiology; Dog and human cardiac preparations; M-cell;