دانلود مقالات ISI درباره Retinoid X Receptor Α + ترجمه فارسی

مکانیزم های آلوستریک گیرنده های هسته ای: بینش از شبیه سازی های محاسباتی

Allosteric mechanisms of nuclear receptors: insights from computational simulations

Keywords: AF-2; activation function 2; AP; alternative pocket; AR; androgen receptor; BF-3; binding function 3; DBD; DNA-binding domain; ER; estrogen receptor; GP; genomic pocket; GR; glucocorticoid receptor; H12; helix 12; HDX; hydrogen/deuterium exchange; LBD; li

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2014 سفارش ترجمه

انسداد گیرنده پروژسترون به طور موثر زنده ماندن سلول بتای جزیره پانکراس را محافظت می کند

Blockage of progesterone receptor effectively protects pancreatic islet beta cell viability

Keywords: PR; progesterone receptor; PIC; pro-inflammatory cytokines; P4; progesterone; Erk; extracellular-signal-regulated kinase 1/2; p53; protein 53; AKT; protein kinase B; TRAF2; tumor necrosis factor receptor-associated factor 2; PR-KO; PR knockout; Mif; mifep

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

گیرنده های هورمون تیروئید و سرطان

Thyroid hormone receptors and cancer

Keywords: BM; basement membrane; ECM; extracellular membrane; EMT; epithelial mesenchymal transition; FAK; focal adhesion kinase; MAPK; mitogen-activated protein kinase; LOH; loss of heterozygosity; NCOR1; nuclear receptor co-repressor 1; MMP; matrix metalloprotein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

PDZ domain containing protein 1 (PDZK1), a modulator of membrane proteins, is regulated by the nuclear receptor THRβ

Keywords: Thyroid hormones; Scaffold protein; PDZ-domain; Gene regulation; Thyroid hormone receptors; 5-HT2A; Serotonin 2A receptor; ABC; ATP-binding cassette transporter; AhR; Transcription factor aryl hydrocarbon receptor; BCRP; Breast cancer resistance protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice

Keywords: 3αHSD; 3alpha-hydroxysteroid reductase; ABCA1; ATP-binding cassette sub-family A member 1; ABCG1; 4, 5 or 8, ATP-binding cassette sub-family G member 1,4, 5 or 8; ACAT2; acetyl-CoA acetyltransferase (Soat2 gene); ACC1; acetyl-CoA carboxylase (Acaca gene)

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Development of a highly sensitive in vitro system to detect and discriminate between vitamin D receptor agonists and antagonists based on split-luciferase technique

Keywords: CYP27B1; 25-hydroxyvitamin D3 1α-hydroxylase; VDR; vitamin D receptor; LBD; ligand binding domain; LucN; N-terminal domain of luciferase; LucC; C-terminal domain of luciferase; SRC-1; steroid receptor coactivating factor 1; RXRα; retinoid X receptor α;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists

Keywords: FXR; farnesoid X receptor; CDCA; chenodeoxycholic acid; CYP7A1; cholesterol 7α-hydroxylase; SHP; small heterodimer partner; RXRα; retinoid X receptor α; 9-cis-RA; 9-cis-retinoic acid; LBD; ligand binding domain; TR-FRET; time-resolved fluorescence reso

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor

Keywords: VDR; vitamin D receptor; RXRα; retinoid X receptor α; LBD; ligand binding domain; VDRE; vitamin D responsive element; LucN; N-terminal domain of luciferase; LucC; C-terminal domain of luciferase; Vitamin D receptor; Bioluminescent sensor; Split lucifera

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of farnesoid X receptor induces RECK expression in mouse liver

Keywords: FXR; farnesoid X receptor; RXRα; retinoid X receptor α; SHP; small heterodimer partner; SREBP-1c; sterol regulatory element-binding protein-1c; PEPCK; phosphoenolpyruvate carboxykinase; RECK; reversion-inducing cysteine rich protein with Kazal motifs; M

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease

Keywords: FXR; farnesoid X receptor; ALD; alcoholic liver disease; SHP; small heterodimer partner; BSEP; bile salt export pump; CYP7A1; cholesterol 7α-hydroxylase; CYP8B1; sterol 12α-hydroxylase; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; CYP2E1; c

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleImpaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-binding domain

Keywords: RXRα; Retinoid X Receptor α; NR; Nuclear Receptors; DBD; DNA-Binding Domain; CA; cholic acid; BA; bile acids; Bile acids; Liver injury; Nuclear receptors; Retinoid x receptor; Apoptosis; DDC; Biliary fibrosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Sex-different effects of tributyltin on brain aromatase, estrogen receptor and retinoid X receptor gene expression in rockfish (Sebastiscus marmoratus)

Keywords: Organotins; Sebastiscus marmoratus; Retinoid X receptor α; Estrogen receptor; Brain; Effects-fish; Environmental toxicology;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation

Keywords: 15d-PGJ2; 15-deoxy-Δ12,14-PGJ2; AA; arachidonic acid; PPARγ; peroxisome proliferator-activated receptor γ; FXR; farnesoid X receptor; SPR; surface plasmon resonance; FQ; fluorescence quenching; HTRF; homo time-resolved fluorescence; BSEP; bile-salt exp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-1 and microRNA-206 suppress LXRα-induced lipogenesis in hepatocytes

Keywords: LXRα/β; Liver X receptor α/β; miRs; MicroRNAs; SREBP-1c; sterol-regulatory element binding protein 1c; FAS; fatty acid synthase; ChREBP; carbohydrate responsive element-binding protein; ACC1; acetyl-CoA carboxylase 1; RXRα; retinoid X receptor α; LX

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Cow's milk increases the activities of human nuclear receptors peroxisome proliferator-activated receptors α and δ and retinoid X receptor α involved in the regulation of energy homeostasis, obesity, and inflammation

Keywords: milk; peroxisome proliferator-activated receptor α; peroxisome proliferator-activated receptor δ; retinoid X receptor α;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of RXRα gene silencing on the porcine adipocyte differentiation in vitro

Keywords: Porcine; Small interfering RNA; Retinoid X receptor α; RXRα; PPARγ; C/EBPα; Preadipocytes; Adipocyte differentiation; In vitro;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR)

Keywords: AR; androgen receptor; β-Gal; β-galactosidase; CYP3A; cytochrome P4503A; DMEM; Dulbecco's modified Eagle medium; DMSO; dimethyl sulfoxide; DR3; direct repeat with 3 nucleotide spacer; EC50; effective concentration for half-maximal response; ER; estrogen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه